Harnessing food-based bioactive compounds to reduce the effects of ultraviolet radiation: a review exploring the link between food and human health

International Journal of Food Science and Technology

Volumn 52, Issue 3, 2017, Pages 595-607

  Ye, Yuhui ^a   Sun Waterhouse, Dongxiao ^a   You, Lijun ^a   Abbasi, Arshad Mehmood ^a,b  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^b Department of Electrical Computer Engineering   (Pakistan)

Author keywords

Flavones; peptides; photoageing; photoprotection; polysaccharides; terpenoids; ultraviolet radiation

Indexed keywords

BIOLOGY; FLAVONOIDS; HEALTH; HEALTH RISKS; LIPIDS; OZONE LAYER; PEPTIDES; POLYSACCHARIDES; RADIATION; ULTRAVIOLET RADIATION;

BIOACTIVE COMPOUNDS; FLAVONES; PHOTO-AGEING; PHOTOPROTECTION; RADIATION INDUCED DAMAGE; SOLAR UV RADIATION; STRATOSPHERIC OZONE; TERPENOIDS;

RADIATION EFFECTS;

EID: 85007579311     PISSN: 09505423     EISSN: 13652621     Source Type: Journal    
DOI: 10.1111/ijfs.13344     Document Type: Review

References (139)

1. ACS (2015). Cancer Facts & Figures 2015. Pp. 4–18. USA: American Cancer Society.
2. Agati, G., Azzarello, E., Pollastri, S. & Tattini, M. (2012). Flavonoids as antioxidants in plants: location and functional significance. Plant Science, 196, 67–76.
3. Agrawal, R. & Kaur, I.P. (2010). Inhibitory effect of encapsulated curcumin on ultraviolet-induced photoaging in mice. Rejuvenation Research, 13, 397–410.
4. Ahene, A., Saxena, S. & Nacht, S. (1994). Photoprotection of solubilized and microdispersed melanin particles. Journal of Investigative Dermatology, 102, 255–269.
5. Ali, M.B., Hahn, E.J. & Paek, K.Y. (2005). Effects of temperature on oxidative stress defense systems, lipid peroxidation and lipoxygenase activity in Phalaenopsis. Plant Physiology and Biochemistry, 43, 213–223.
6. Allan, A.C. & Fluhr, R. (1997). Two distinct sources of elicited reactive oxygen species in tobacco epidermal cells. The Plant Cell, 9, 1559–1572.
7. Antognoni, F., Zheng, S., Pagnucco, C., Baraldi, R., Poli, F. & Biondi, S. (2007). Induction of flavonoid production by UV-B radiation in Passiflora quadrangularis callus cultures. Fitoterapia, 78, 345–352.
8. Arts, I.C. & Hollman, P.C. (2005). Polyphenols and disease risk in epidemiologic studies. The American Journal of Clinical Nutrition, 81, 317–325.
9. Aylon, Y. & Oren, M. (2007). Living with p53, dying of p53. Cell, 130, 597–600.
10. Bae, J.Y., Lim, S.S., Kim, S.J. et al. (2009). Bog blueberry anthocyanins alleviate photoaging in ultraviolet-B irradiation-induced human dermal fibroblasts. Molecular Nutrition & Food Research, 53, 726–738.
11. Barta, C., Kálai, T., Hideg, K., Vass, I. & Hideg, É. (2004). Differences in the ROS-generating efficacy of various ultraviolet wavelengths in detached spinach leaves. Functional Plant Biology, 31, 23–28.
12. Blanding, C.R., Simmons, S.J., Casati, P., Walbot, V. & Stapleton, A.E. (2007). Coordinated regulation of maize genes during increasing exposure to ultraviolet radiation: identification of ultraviolet-responsive genes, functional processes and associated potential promoter motifs. Plant Biotechnology Journal, 5, 677–695.
13. Booij-James, I.S., Dube, S.K., Jansen, M.A., Edelman, M. & Mattoo, A.K. (2000). Ultraviolet-B radiation impacts light-mediated turnover of the photosystem II reaction center heterodimer in Arabidopsis mutants altered in phenolic metabolism. Plant Physiology, 124, 1275–1284.
14. Bracco, U., Löliger, J. & Viret, J.L. (1981). Production and use of natural antioxidants. Journal of the American Oil Chemists’ Society, 58, 686–690.
15. Brosche, M. & Strid, Å. (2003). Molecular events following perception of ultraviolet-B radiation by plants. Physiologia Plantarum, 117, 1–10.
16. Brown, L. & Benchimol, S. (2006). The Involvement of MAPK signaling pathways in determining the cellular response to p53 activation cell cycle arrest or apoptosis. Journal of Biological Chemistry, 281, 3832–3840.
17. Cao, C. & Wan, Y. (2009). Parameters of protection against ultraviolet radiation-induced skin cell damage. Journal of Cellular Physiology, 220, 277–284.
18. Chen, C.H. (2007). Study of anti-tumor effect of Acanthopanax trifoliatus; understand of knowledge and attitude of Chinese herb between nurses and society in eastern Taiwan. Ph.D Thesis. Taiwan: Tzu Chi University.
19. Chen, H., Zhang, M., Qu, Z. & Xie, B. (2008). Antioxidant activities of different fractions of polysaccharide conjugates from green tea (Camellia Sinensis). Food Chemistry, 106, 559–563.
20. Chiang, H.M., Lin, J.W., Hsiao, P.L., Tsai, S.Y. & Wen, K.C. (2011). Hydrolysates of citrus plants stimulate melanogenesis protecting against UV-induced dermal damage. Phytotherapy Research, 25, 569–576.
21. Cho, S., Won, C.H., Lee, D.H. et al. (2009). Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin: a randomized, double-blind, placebo-controlled study. Journal of Medicinal Food, 12, 1252–1259.
22. Cook, N. & Samman, S. (1996). Flavonoids—chemistry, metabolism, cardioprotective effects, and dietary sources. The Journal of Nutritional Biochemistry, 7, 66–76.
23. Copolovici, L.O., Filella, I., Llusià, J., Niinemets, Ü. & Peñuelas, J. (2005). The capacity for thermal protection of photosynthetic electron transport varies for different monoterpenes in Quercus ilex. Plant Physiology, 139, 485–496.
24. Costa, D., Galvão, A.M., Di Paolo, R.E. et al. (2015). Photochemistry of the hemiketal form of anthocyanins and its potential role in plant protection from UV-B radiation. Tetrahedron, 71, 3157–3162.
25. Dai, J., Ma, H., Fan, J. et al. (2011). Crude polysaccharide from an anti-UVB cell clone of Bupleurum scorzonerifolium protect HaCaT cells against UVB-induced oxidative stress. Cytotechnology, 63, 599–607.
26. Dargitz, C., Russell, A., Bingham, M., Achay, Z., Jimenez-Flores, R. & Laiho, L.H. (2012). Milk phospholipid's protective effects against UV damage in skin equivalent models. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues X, 8825, 1–9.
27. De Lima-Bessa, K.M., Armelini, M.G., Chiganças, V. et al. (2008). CPDs and 6-4PPs play different roles in UV-induced cell death in normal and NER-deficient human cells. DNA Repair, 7, 303–312.
28. Delfine, S., Csiky, O., Seufert, G. & Loreto, F. (2000). Fumigation with exogenous monoterpenes of a non-isoprenoid-emitting oak (Quercus suber): Monoterpene acquisition, translocation, and effect on the photosynthetic properties at high temperatures. New Phytologist, 146, 27–36.
29. Dornelas, M.C. & Mazzafera, P. (2007). A genomic approach to characterization of the Citrus terpene synthase gene family. Genetics and Molecular Biology, 30, 832–840.
30. Dorr, R.T., Ertl, G., Levine, N. et al. (2004). Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers. Archives of Dermatology, 140, 827–835.
31. Eller, M.S., Hadshiew, I.M. & Gilchrest, B.A. (2002). The role of DNA damage in melanogenesis: Potential role for telomeres. In: Biologic Effects of Light 2001 (edited by M.F. Holick). Pp. 91–101. Boston: Springer US.
32. Falcone Ferreyra, M.L., Rius, S., Emiliani, J. et al. (2010). Cloning and characterization of a UV-B-inducible maize flavonol synthase. The Plant Journal, 62, 77–91.
33. Fernandez, E., Rodriguez, G., Cocera, M. et al. (2015). Advanced lipid systems containing beta-carotene: stability under UV-vis radiation and application on porcine skin in vitro. Physical Chemistry Chemical Physics, 17, 18710–18721.
34. Ferreira da Silva, P., Paulo, L., Barbafina, A., Elisei, F., Quina, F.H. & Maçanita, A.L. (2012). Photoprotection and the photophysics of acylated anthocyanins. Chemistry-A European Journal, 18, 3736–3744.
35. Filip, A., Daicoviciu, D., Clichici, S. et al. (2011). The effects of grape seeds polyphenols on SKH-1 mice skin irradiated with multiple doses of UV-B. Journal of Photochemistry and Photobiology B-Biology, 105, 133–142.
36. Fujii, T., Okuda, T., Yasui, N., Wakaizumi, M., Ikami, T. & Ikeda, K. (2013). Effects of amla extract and collagen peptide on UVB-induced photoaging in hairless mice. Journal of Functional Foods, 5, 451–459.
37. Gao, Y., Liu, W., Zhou, B., Li, W. & Luo, D. (2010). Ginsenoside-Rg1 protects human dermal fibroblasts against 8-methoxypsoralen plus ultraviolet A-induced photoaging through p53-dependent signaling pathways. Chinese Pharmacological Bulletin, 26, 383–387.
38. Gil, M., Pontin, M., Berli, F., Bottini, R. & Piccoli, P. (2012). Metabolism of terpenes in the response of grape (Vitis vinifera L.) leaf tissues to UV-B radiation. Phytochemistry, 77, 89–98.
39. Gil, M., Bottini, R., Berli, F., Pontin, M., Silva, M.F. & Piccoli, P. (2013). Volatile organic compounds characterized from grapevine (Vitis vinifera L. cv. Malbec) berries increase at pre-harvest and in response to UV-B radiation. Phytochemistry, 96, 148–157.
40. Gitz, D.C., Liu, L. & McClure, J.W. (1998). Phenolic metabolism, growth, and uv–b tolerance in phenylalanine ammonia-lyase-inhibited red cabbage seedlings. Phytochemistry, 49, 377–386.
41. González, S., Fernández-Lorente, M. & Gilaberte-Calzada, Y. (2008). The latest on skin photoprotection. Clinics in Dermatology, 26, 614–626.
42. Goswami, S. & Haldar, C. (2015). Melatonin as a possible antidote to UV radiation induced cutaneous damages and immune-suppression: an overview. Journal of Photochemistry and Photobiology B-Biology, 153, 281–288.
43. Halliwell, B. & Gutteridge, J.M. (2015). Free Radicals in Biology and Medicine. Pp. 173–179. USA: Oxford University Press.
44. Havaux, M. (1998). Carotenoids as membrane stabilizers in chloroplasts. Trends in Plant Science, 3, 147–151.
45. Heim, K.E., Tagliaferro, A.R. & Bobilya, D.J. (2002). Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. The Journal of Nutritional Biochemistry, 13, 572–584.
46. Herce, H.D., Deng, W., Helma, J., Leonhardt, H. & Cardoso, M.C. (2013). Visualization and targeted disruption of protein interactions in living cells. Nature Communications, 4, 1–11.
47. Hideg, É., Barta, C., Kálai, T., Vass, I., Hideg, K. & Asada, K. (2002). Detection of singlet oxygen and superoxide with fluorescent sensors in leaves under stress by photoinhibition or UV radiation. Plant and Cell Physiology, 43, 1154–1164.
48. Hideg, É., Jansen, M.A. & Strid, Å. (2013). UV-B exposure, ROS, and stress: inseparable companions or loosely linked associates? Trends in Plant Science, 18, 107–115.
49. Hiraku, Y., Ito, K., Hirakawa, K. & Kawanishi, S. (2007). Photosensitized DNA damage and its protection via a novel mechanism. Photochemistry and Photobiology, 83, 205–212.
50. Hou, H., Li, B., Zhao, X. et al. (2009). The effect of pacific cod (Gadus macrocephalus) skin gelatin polypeptides on UV radiation-induced skin photoaging in ICR mice. Food Chemistry, 115, 945–950.
51. Houghton, P. (2007). Ethnopharmacology of medicinal plants: Asia and the Pacific. British Journal of Clinical Pharmacology, 64, 248.
52. Jenkins, G.I. & Brown, B.A. (2007). UV-B perception and signal transduction. Light and Plant Development, 30, 155–182.
53. Jintang, S., Alei, F., Yun, Z. et al. (2010). Fucoidan increases TNF-α-induced MMP-9 secretion in monocytic cell line U937. Inflammation Research, 59, 271–276.
54. Julkunen-Tiitto, R., Häggman, H., Aphalo, P.J., Lavola, A., Tegelberg, R. & Veteli, T. (2005). Growth and defense in deciduous trees and shrubs under UV-B. Environmental Pollution, 137, 404–414.
55. Keeling, C.I. & Bohlmann, J. (2006). Genes, enzymes and chemicals of terpenoid diversity in the constitutive and induced defence of conifers against insects and pathogens. New Phytologist, 170, 657–675.
56. Kielbassa, C., Roza, L. & Epe, B. (1997). Wavelength dependence of oxidative DNA damage induced by UV and visible light. Carcinogenesis, 18, 811–816.
57. Kilian, J., Whitehead, D., Horak, J. et al. (2007). The AtGenExpress global stress expression data set: protocols, evaluation and model data analysis of UV-B light, drought and cold stress responses. The Plant Journal, 50, 347–363.
58. Kim, S.J., Sancheti, S.A., Sancheti, S.S., Um, B.H., Yu, S.M. & Seo, S.Y. (2010). Effect of 1, 2, 3, 4, 6-penta-O-galloyl-beta-D-glucose on elastase and hyaluronidase activities and its type II collagen expression. Acta Poloniae Pharmaceutica, 67, 145–150.
59. Kim, J., Lee, C.W., Kim, E.K. et al. (2011). Inhibition effect of Gynura procumbens extract on UV-B-induced matrix-metalloproteinase expression in human dermal fibroblasts. Journal of Ethnopharmacology, 137, 427–433.
60. Kimura, Y., Sumiyoshi, M. & Kobayashi, T. (2014). Whey peptides prevent chronic ultraviolet B radiation–induced skin aging in melanin-possessing male hairless mice. The Journal of Nutrition, 144, 27–32.
61. Lee, T.K., Poon, R.T., Wo, J.Y. et al. (2007). Lupeol suppresses cisplatin-induced nuclear factor-κB activation in head and neck squamous cell carcinoma and inhibits local invasion and nodal metastasis in an orthotopic nude mouse model. Cancer Research, 67, 8800–8809.
62. Lee, S.H., Matsushima, K., Miyamoto, K. & Oe, T. (2016). UV irradiation-induced methionine oxidation in human skin keratins: mass spectrometry-based non-invasive proteomic analysis. Journal of Proteomics, 133, 54–56.
63. Li, J., Ou Lee, T.M., Raba, R., Amundson, R.G. & Last, R.L. (1993). Arabidopsis flavonoid mutants are hypersensitive to UV-B irradiation. The Plant Cell, 5, 171–179.
64. Lichtenthaler, H.K., Schwender, J., Disch, A. & Rohmer, M. (1997). Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate-independent pathway. FEBS Letters, 400, 271–274.
65. Liu, M., Li, X., Liu, Y. & Cao, B. (2013). Regulation of flavanone 3-hydroxylase gene involved in the flavonoid biosynthesis pathway in response to UV-B radiation and drought stress in the desert plant, Reaumuria soongorica. Plant Physiology and Biochemistry, 73, 161–167.
66. Llorens, L., Badenes-Pérez, F.R., Julkunen-Tiitto, R., Zidorn, C., Fereres, A. & Jansen, M.A.K. (2015). The role of UV-B radiation in plant sexual reproduction. Perspectives in Plant Ecology, Evolution and Systematics, 17, 243–254.
67. Logemann, E., Tavernaro, A., Schulz, W., Somssich, I.E. & Hahlbrock, K. (2000). UV light selectively coinduces supply pathways from primary metabolism and flavonoid secondary product formation in parsley. Proceedings of the National Academy of Sciences, 97, 1903–1907.
68. Loreto, F. & Velikova, V. (2001). Isoprene produced by leaves protects the photosynthetic apparatus against ozone damage, quenches ozone products, and reduces lipid peroxidation of cellular membranes. Plant Physiology, 127, 1781–1787.
69. Loreto, F., Förster, A., Dürr, M., Csiky, O. & Seufert, G. (1998). On the monoterpene emission under heat stress and on the increased thermotolerance of leaves of Quercus ilex L. fumigated with selected monoterpenes. Plant, Cell & Environment, 21, 101–107.
70. Maity, N., Nema, N.K., Abedy, M.K., Sarkar, B.K. & Mukherjee, P.K. (2011). Exploring Tagetes erecta Linn flower for the elastase, hyaluronidase and MMP-1 inhibitory activity. Journal of Ethnopharmacology, 137, 1300–1305.
71. Mateos Aparicio, I., Mateos Peinado, C., Jiménez Escrig, A. & Rupérez, P. (2010). Multifunctional antioxidant activity of polysaccharide fractions from the soybean byproduct okara. Carbohydrate Polymers, 82, 245–250.
72. Mayer, U.M., Muller, Y. & Bluthner, K. (2001). The vitamins C and E protect cultures of bovine lens epithelia from light toxicity (blue light 430 nm, UV-A-light 300-400 nm). Klinische Monatsblatter Fur Augenheilkunde, 218, 116–120.
73. Middleton, E. Jr. (1998). Effect of plant flavonoids on immune and inflammatory cell function. In: Flavonoids in the Living System (edited by M. Buslig) Pp. 175–182 New York: Springer.
74. Moon, H.J., Lee, S.H., Ku, M.J. et al. (2009a). Fucoidan inhibits UVB-induced MMP-1 promoter expression and down regulation of type I procollagen synthesis in human skin fibroblasts. European Journal of Dermatology, 19, 129–134.
75. Moon, H.J., Park, K.S., Ku, M.J. et al. (2009b). Effect of Costaria costata fucoidan on expression of matrix metalloproteinase-1 promoter, mRNA, and protein. Journal of Natural Products, 72, 1731–1734.
76. Morley, N., Clifford, T., Salter, L., Campbell, S., Gould, D. & Curnow, A. (2005). The green tea polyphenol (−)-epigallocatechin gallate and green tea can protect human cellular DNA from ultraviolet and visible radiation-induced damage. Photodermatology, Photoimmunology & Photomedicine, 21, 15–22.
77. Murakami, H. & Kobayashi, H. (2010). Amino acid composition promoting collagen synthesis. Google Patents US7645796 B2.
78. Murphy, T.M. (1997). Resistance of plants to the effects of ultraviolet radiation. Mechanisms of Environmental Stress Resistence in Plants, 1, 151–190.
79. Nagaraj, M., Sunitha, S. & Varalakshmi, P. (2000). Effect of lupeol, a pentacyclic triterpene, on the lipid peroxidation and antioxidant status in rat kidney after chronic cadmium exposure. Journal of Applied Toxicology, 20, 413–417.
80. Neely, W., Martin, J. & Barker, S. (1988). Products and relative reaction rates of the oxidation of tocopherols with singlet molecular oxygen. Photochemistry and Photobiology, 48, 423–428.
81. Offord, E.A., Gautier, J.C., Avanti, O. et al. (2002). Photoprotective potential of lycopene, β-carotene, vitamin E, vitamin C and carnosic acid in UVA-irradiated human skin fibroblasts. Free Radical Biology and Medicine, 32, 1293–1303.
82. Parihar, P., Singh, S., Singh, R., Singh, V.P. & Prasad, S.M. (2015). Changing scenario in plant UV-B research: UV-B from a generic stressor to a specific regulator. Journal of Photochemistry and Photobiology B-Biology, 153, 334–343.
83. Park, H.Y. & Yaar, M. (2001). Biology of melanocytes. Science, 292, 1718–1722.
84. Pawelek, J., Bolognia, J., McLane, J., Murray, M., Osber, M. & Slominski, A. (1988). A possible role for melanin precursors in regulating both pigmentation and proliferation of melanocytes. Progress in Clinical and Biological Research, 256, 143–154.
85. Pontin, M.A., Piccoli, P.N., Francisco, R., Bottini, R., Martinez-Zapater, J.M. & Lijavetzky, D. (2010). Transcriptome changes in grapevine (Vitis vinifera L.) cv. Malbec leaves induced by ultraviolet-B radiation. BMC Plant Biology, 10, 224.
86. Pourmorad, F., Hosseinimehr, S. & Shahabimajd, N. (2006). Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. African Journal of Biotechnology, 5, 1142–1145.
87. Prota, G. (1995). The chemistry of melanins and melanogenesis. In: Fortschritte der Chemie organischer Naturstoffe/Progress in the Chemistry of Organic Natural Products (edited by W. Herz, G.W. Kirby, R.E. Moore, W. Steglich & C. Tamm). Pp. 93–148. Vienna: Springer.
88. Prota, G. (2012). Melanins and Melanogenesis. Pp. 5–7. USA: Academic Press.
89. Rass, K. & Reichrath, J. (2008). UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer. In: Sunlight, Vitamin D and Skin Cancer (edited by J. Reichrath) Pp. 162–178 Germany: Springer.
90. Rice Evans, C.A., Miller, N.J. & Paganga, G. (1996). Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biology and Medicine, 20, 933–956.
91. Ries, G., Heller, W., Puchta, H., Sandermann, H., Seidlitz, H.K. & Hohn, B. (2000). Elevated UV-B radiation reduces genome stability in plants. Nature, 406, 98–101.
92. Riou, L., Eveno, E., van Hoffen, A., van Zeeland, A.A., Sarasin, A. & Mullenders, L.H. (2004). Differential repair of the two major UV-induced photolesions in trichothiodystrophy fibroblasts. Cancer Research, 64, 889–894.
93. Rogers, H.W., Weinstock, M.A., Feldman, S.R. & Coldiron, B.M. (2015). Incidence estimate of nonmelanoma skin cancer (keratinocyte carcinomas) in the US population, 2012. JAMA Dermatology, 151, 1081–1086.
94. Ross, J.A. & Kasum, C.M. (2002). Dietary flavonoids: bioavailability, metabolic effects, and safety. Annual review of Nutrition, 22, 19–34.
95. Rozema, J., van de Staaij, J., Björn, L.O. & Caldwell, M. (1997). UV-B as an environmental factor in plant life: stress and regulation. Trends in Ecology & Evolution, 12, 22–28.
96. Ryan, K.G., Swinny, E.E., Winefield, C. & Markham, K.R. (2001). Flavonoids and UV photoprotection in Arabidopsis mutants. Zeitschrift für Naturforschung C, 56, 745–754.
97. Saewan, N. & Jimtaisong, A. (2015). Natural products as photoprotection. Journal of Cosmetic Dermatology, 14, 47–63.
98. Saleem, M., Alam, A., Arifin, S., Shah, M.S., Ahmed, B. & Sultana, S. (2001). Lupeol, a triterpene, inhibits early responses of tumor promotion induced by benzoyl peroxide in murine skin. Pharmacological Research, 43, 127–134.
99. Saleem, M., Afaq, F., Adhami, V.M. & Mukhtar, H. (2004). Lupeol modulates NF-κB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene, 23, 5203–5214.
100. Saleem, M., Maddodi, N., Zaid, M.A. et al. (2008). Lupeol inhibits growth of highly aggressive human metastatic melanoma cells in vitro and in vivo by inducing apoptosis. Clinical Cancer Research, 14, 2119–2127.
101. Saradhi, P.P., AliaArora, S. & Prasad, K. (1995). Proline accumulates in plants exposed to UV radiation and protects them against UV-induced peroxidation. Biochemical and Biophysical Research Communications, 209, 1–5.
102. Schallreuter, K.U., Lemke, K.R., Hill, H.Z. & Wood, J.M. (1994). Thioredoxin reductase induction coincides with melanin biosynthesis in brown and black guinea pigs and in murine melanoma cells. Journal of Investigative Dermatology, 103, 820–824.
103. Sevgi, K., Tepe, B. & Sarikurkcu, C. (2015). Antioxidant and DNA damage protection potentials of selected phenolic acids. Food and Chemical Toxicology, 77, 12–21.
104. Sharkey, T.D. (1995). Why plants emit isoprene. Nature, 374, 769.
105. Sharkey, T.D. (1996). Isoprene synthesis by plants and animals. Endeavour, 20, 74–78.
106. Shih, M.F. & Cherng, J.Y. (2012). Protective effects of Chlorella-derived peptide against UVC-induced cytotoxicity through inhibition of caspase-3 activity and reduction of the expression of phosphorylated FADD and cleaved PARP-1 in skin fibroblasts. Molecules, 17, 9116–9128.
107. Silva, A., Seidl, C., Furusho, A., Boeno, M., Dieamant, G. & Weffort-Santos, A. (2013). In vitro evaluation of the efficacy of commercial green tea extracts in UV protection. International Journal of Cosmetic Science, 35, 69–77.
108. Singh, M., Kaur, M. & Silakari, O. (2014). Flavones: an important scaffold for medicinal chemistry. European Journal of Medicinal Chemistry, 84, 206–239.
109. Singsaas, E.L., Lerdau, M., Winter, K. & Sharkey, T.D. (1997). Isoprene increases thermotolerance of isoprene-emitting species. Plant Physiology, 115, 1413–1420.
110. Steele, C.L., Crock, J., Bohlmann, J. & Croteau, R. (1998). Sesquiterpene synthases from grand fir (Abies grandis) comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase. Journal of Biological Chemistry, 273, 2078–2089.
111. Stewart, B. & Wild, C.P. (2015). World Cancer Report 2014. Pp. 723–737. France: International Agency for Research on Cancer.
112. Stiefel, C. & Schwack, W. (2015). Photoprotection in changing times - UV filter efficacy and safety, sensitization processes and regulatory aspects. International Journal of Cosmetic Science, 37, 2–30.
113. Stochmal, A. & Oleszek, W. (2007). Effect of acylation of flavones with hydroxycinnamic acids on their spectral characteristics. Natural Product Communications, 2, 571–574.
114. Strid, Å., Chow, W.S. & Anderson, J.M. (1994). UV-B damage and protection at the molecular level in plants. Photosynthesis Research, 39, 475–489.
115. Sun, L., Zhang, Y. & Zhuang, Y. (2013). Antiphotoaging effect and purification of an antioxidant peptide from tilapia (Oreochromis niloticus) gelatin peptides. Journal of Functional Foods, 5, 154–162.
116. Sunitha, S., Nagaraj, M. & Varalakshmi, P. (2001). Hepatoprotective effect of lupeol and lupeol linoleate on tissue antioxidant defence system in cadmium-induced hepatotoxicity in rats. Fitoterapia, 72, 516–523.
117. Sun-Waterhouse, D. (2011). The development of fruit-based functional foods targeting the health and wellness market: a review. International Journal of Food Science & Technology, 46, 899–920.
118. Taylor, R.P., Lalvani, K.S. & Lalvani, A. (2015). Composition useful for protecting skin against effects of winter, comprises bio-marine collagen, grape seed extract, pine bark extract, green tea extract, lycopene, blackcurrant seed oil, alpha lipoic acid and co-enzyme Q10. Patent WO2015062615-A1.
119. Tiraravesit, N., Yakaew, S., Rukchay, R. et al. (2015). Artocarpus altilis heartwood extract protects skin against UVB in vitro and in vivo. Journal of Ethnopharmacology, 175, 153–162.
120. Trapp, S. & Croteau, R. (2001). Defensive resin biosynthesis in conifers. Annual Review of Plant Biology, 52, 689–724.
121. Villareal, M.O., Han, J., Ikuta, K. & Isoda, H. (2011). Daphnane diterpene hirsein B downregulates melanogenesis in B16 murine melanoma cells by cAMP pathway inhibition. BMC proceedings, 5, 68.
122. Vorob'eva, L., Khodzhaev, E.Y. & Vustin, M. (2011). Antistress cross-protection of UV-irradiated yeast cells with participation of extracellular peptide factors. Applied Biochemistry and Microbiology, 47, 264–269.
123. Wan, H., Yuan, J., Shan, X., Wu, Q. & Shi, N. (2011). Structure and bio-properties of extracellular polysaccharide from Bacillus sp. strain LBP32 Isolated from LUOBOPO desert. Biotechnology and Bioprocess Engineering, 16, 761–768.
124. Wang, S.Y., Wu, J.H., Shyur, L.F., Kuo, Y.H. & Chang, S.T. (2002). Antioxidant activity of abietane-type diterpenes from heartwood of Taiwania cryptomerioides Hayata. Holzforschung, 56, 487–492.
125. Wang, H., Jiang, X., Mu, H., Liang, X. & Guan, H. (2007). Structure and protective effect of exopolysaccharide from P. agglomerans strain KFS-9 against UV radiation. Microbiological Research, 162, 124–129.
126. Wang, J., Zhang, Q., Zhang, Z., Song, H. & Li, P. (2010). Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica. International Journal of Biological Macromolecules, 46, 6–12.
127. Wei, X., Liu, Y., Xiao, J. & Wang, Y. (2009). Protective effects of tea polysaccharides and polyphenols on skin. Journal of Agricultural and Food Chemistry, 57, 7757–7762.
128. Wen, L., Gao, Q., Ma, C. et al. (2016). Effect of polysaccharides from Tremella fuciformis on UV-induced photoaging. Journal of Functional Foods, 20, 400–410.
129. WHO (2016). How common is skin cancer? Available at: http://www.who.int/uv/faq/skincancer/en/index1.html. Accessed 4 February 2016.
130. Williams, J.Z., Abumrad, N. & Barbul, A. (2002). Effect of a specialized amino acid mixture on human collagen deposition. Annals of Surgery, 236, 369–375.
131. Williams, S., Tamburic, S. & Lally, C. (2009). Eating chocolate can significantly protect the skin from UV light. Journal of Cosmetic Dermatology, 8, 169–173.
132. Wolf, L., Rizzini, L., Stracke, R., Ulm, R. & Rensing, S.A. (2010). The molecular and physiological responses of Physcomitrella patens to ultraviolet-B radiation. Plant Physiology, 153, 1123–1134.
133. Wong, W., Wu, J. & Benzie, I. (2011). Photoprotective potential of Cordyceps polysaccharides against ultraviolet B radiation-induced DNA damage to human skin cells. British Journal of Dermatology, 164, 980–986.
134. Wu, Y., Tian, Q., Li, L. et al. (2013). Inhibitory effect of antioxidant peptides derived from Pinctada fucata protein on ultraviolet-induced photoaging in mice. Journal of Functional Foods, 5, 527–538.
135. Yang, B., Wang, J., Zhao, M., Liu, Y., Wang, W. & Jiang, Y. (2006). Identification of polysaccharides from pericarp tissues of litchi (Litchi chinensis Sonn.) fruit in relation to their antioxidant activities. Carbohydrate Research, 341, 634–638.
136. Yang, B., Zhao, M., Shi, J., Yang, N. & Jiang, Y. (2008). Effect of ultrasonic treatment on the recovery and DPPH radical scavenging activity of polysaccharides from longan fruit pericarp. Food Chemistry, 106, 685–690.
137. Zhang, H., Wang, Z.Y., Yang, L., Yang, X., Wang, X. & Zhang, Z. (2011). In vitro antioxidant activities of sulfated derivatives of polysaccharides extracted from Auricularia auricular. International Journal of Molecular Sciences, 12, 3288–3302.
138. Zhou, X., Gong, Z., Su, Y., Lin, J. & Tang, K. (2009). Cordyceps fungi: natural products, pharmacological functions and developmental products. Journal of Pharmacy and Pharmacology, 61, 279–291.
139. Zhuang, Y., Hou, H., Zhao, X., Zhang, Z. & Li, B. (2009). Effects of collagen and collagen hydrolysate from jellyfish (Rhopilema esculentum) on mice skin photoaging induced by UV irradiation. Journal of Food Science, 74, 183–188.