메뉴 건너뛰기




Volumn 113, Issue 52, 2016, Pages E8379-E8386

Molecular profiling of single circulating tumor cells from lung cancer patients

(23)  Park, Seung Min a   Wong, Dawson J b   Ooi, Chin Chun b   Kurtz, David M a,b   Vermesh, Ophir a   Aalipour, Amin a   Suh, Susie c   Pian, Kelsey L b   Chabon, Jacob J a   Lee, Sang Hun d   Jamali, Mehran a   Say, Carmen a   Carter, Justin N a   Lee, Luke P d   Kuschner, Ware G a,e   Schwartz, Erich J a   Shrager, Joseph B a   Neal, Joel W a,f   Wakelee, Heather A a,f   Diehn, Maximilian a,f   more..


Author keywords

Circulating tumor cells; Microfluidics; Rare cell sorting; Reverse transcription PCR; Single cell analysis

Indexed keywords

ALDEHYDE DEHYDROGENASE; DEOXYRIBONUCLEASE I; GENOMIC DNA; MAGNETIC NANOPARTICLE; SCATTER FACTOR RECEPTOR; TELOMERASE REVERSE TRANSCRIPTASE; VASCULOTROPIN; VIMENTIN; PTPRC PROTEIN, HUMAN; RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASE C; TUMOR MARKER;

EID: 85007494746     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1608461113     Document Type: Article
Times cited : (90)

References (56)
  • 1
    • 79952415252 scopus 로고    scopus 로고
    • Emerging molecular biomarkers-bloodbased strategies to detect and monitor cancer
    • Hanash SM, Baik CS, Kallioniemi O (2011) Emerging molecular biomarkers-bloodbased strategies to detect and monitor cancer. Nat Rev Clin Oncol 8(3):142-150.
    • (2011) Nat Rev Clin Oncol , vol.8 , Issue.3 , pp. 142-150
    • Hanash, S.M.1    Baik, C.S.2    Kallioniemi, O.3
  • 2
    • 84896713649 scopus 로고    scopus 로고
    • Molecular analysis of circulating tumour cells-biology and biomarkers
    • Krebs MG, et al. (2014) Molecular analysis of circulating tumour cells-biology and biomarkers. Nat Rev Clin Oncol 11(3):129-144.
    • (2014) Nat Rev Clin Oncol , vol.11 , Issue.3 , pp. 129-144
    • Krebs, M.G.1
  • 3
    • 0032804666 scopus 로고    scopus 로고
    • Optical tracking and detection of immunomagnetically selected and aligned cells
    • Tibbe AG, et al. (1999) Optical tracking and detection of immunomagnetically selected and aligned cells. Nat Biotechnol 17(12):1210-1213.
    • (1999) Nat Biotechnol , vol.17 , Issue.12 , pp. 1210-1213
    • Tibbe, A.G.1
  • 4
    • 37549002543 scopus 로고    scopus 로고
    • Isolation of rare circulating tumour cells in cancer patients by microchip technology
    • Nagrath S, et al. (2007) Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature 450(7173):1235-1239.
    • (2007) Nature , vol.450 , Issue.7173 , pp. 1235-1239
    • Nagrath, S.1
  • 5
    • 78649872067 scopus 로고    scopus 로고
    • Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
    • Stott SL, et al. (2010) Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc Natl Acad Sci USA 107(43):18392-18397.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.43 , pp. 18392-18397
    • Stott, S.L.1
  • 6
    • 84888990964 scopus 로고    scopus 로고
    • Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells
    • Castro CM, et al. (2014) Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells. Lab Chip 14(1):14-23.
    • (2014) Lab Chip , vol.14 , Issue.1 , pp. 14-23
    • Castro, C.M.1
  • 7
    • 62649158232 scopus 로고    scopus 로고
    • Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device
    • Talasaz AH, et al. (2009) Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device. Proc Natl Acad Sci USA 106(10):3970-3975.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.10 , pp. 3970-3975
    • Talasaz, A.H.1
  • 8
    • 84889019347 scopus 로고    scopus 로고
    • Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips
    • Earhart CM, et al. (2014) Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips. Lab Chip 14(1):78-88.
    • (2014) Lab Chip , vol.14 , Issue.1 , pp. 78-88
    • Earhart, C.M.1
  • 9
    • 84934437818 scopus 로고    scopus 로고
    • A microfluidic device for label-free, physical capture of circulating tumor cell clusters
    • Sarioglu AF, et al. (2015) A microfluidic device for label-free, physical capture of circulating tumor cell clusters. Nat Methods 12(7):685-691.
    • (2015) Nat Methods , vol.12 , Issue.7 , pp. 685-691
    • Sarioglu, A.F.1
  • 10
    • 84858335921 scopus 로고    scopus 로고
    • Analysis of circulating tumor cells in patients with non-small cell lung cancer using epithelial marker-dependent and-independent approaches
    • Krebs MG, et al. (2012) Analysis of circulating tumor cells in patients with non-small cell lung cancer using epithelial marker-dependent and-independent approaches. J Thorac Oncol 7(2):306-315.
    • (2012) J Thorac Oncol , vol.7 , Issue.2 , pp. 306-315
    • Krebs, M.G.1
  • 11
    • 84889067161 scopus 로고    scopus 로고
    • Size-selective collection of circulating tumor cells using Vortex technology
    • Sollier E, et al. (2014) Size-selective collection of circulating tumor cells using Vortex technology. Lab Chip 14(1):63-77.
    • (2014) Lab Chip , vol.14 , Issue.1 , pp. 63-77
    • Sollier, E.1
  • 12
    • 84875970076 scopus 로고    scopus 로고
    • Inertial focusing for tumor antigen-dependent and-independent sorting of rare circulating tumor cells
    • Ozkumur E, et al. (2013) Inertial focusing for tumor antigen-dependent and-independent sorting of rare circulating tumor cells. Sci Transl Med 5(179):179ra47.
    • (2013) Sci Transl Med , vol.5 , Issue.179 , pp. 179ra47
    • Ozkumur, E.1
  • 13
    • 84937402029 scopus 로고    scopus 로고
    • Biodegradable nano-films for capture and non-invasive release of circulating tumor cells
    • Li W, et al. (2015) Biodegradable nano-films for capture and non-invasive release of circulating tumor cells. Biomaterials 65:93-102.
    • (2015) Biomaterials , vol.65 , pp. 93-102
    • Li, W.1
  • 14
    • 84908115631 scopus 로고    scopus 로고
    • Nanostructure embedded microchips for detection, isolation, and characterization of circulating tumor cells
    • Lin M, et al. (2014) Nanostructure embedded microchips for detection, isolation, and characterization of circulating tumor cells. Acc Chem Res 47(10):2941-2950.
    • (2014) Acc Chem Res , vol.47 , Issue.10 , pp. 2941-2950
    • Lin, M.1
  • 15
    • 84885482664 scopus 로고    scopus 로고
    • Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets
    • Yoon HJ, et al. (2013) Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets. Nat Nanotechnol 8(10):735-741.
    • (2013) Nat Nanotechnol , vol.8 , Issue.10 , pp. 735-741
    • Yoon, H.J.1
  • 16
    • 84856948211 scopus 로고    scopus 로고
    • Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers
    • Marrinucci D, et al. (2012) Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers. Phys Biol 9(1):016003.
    • (2012) Phys Biol , vol.9 , Issue.1 , pp. 016003
    • Marrinucci, D.1
  • 17
    • 47949114668 scopus 로고    scopus 로고
    • Detection of mutations in EGFR in circulating lung-cancer cells
    • Maheswaran S, et al. (2008) Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med 359(4):366-377.
    • (2008) N Engl J Med , vol.359 , Issue.4 , pp. 366-377
    • Maheswaran, S.1
  • 18
    • 84855439050 scopus 로고    scopus 로고
    • Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis
    • Devriese LA, et al. (2012) Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis. Lung Cancer 75(2):242-247.
    • (2012) Lung Cancer , vol.75 , Issue.2 , pp. 242-247
    • Devriese, L.A.1
  • 19
    • 70449598075 scopus 로고    scopus 로고
    • Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR
    • Sieuwerts AM, et al. (2009) Molecular characterization of circulating tumor cells in large quantities of contaminating leukocytes by a multiplex real-time PCR. Breast Cancer Res Treat 118(3):455-468.
    • (2009) Breast Cancer Res Treat , vol.118 , Issue.3 , pp. 455-468
    • Sieuwerts, A.M.1
  • 20
    • 84904061727 scopus 로고    scopus 로고
    • Blood-based analyses of cancer: Circulating tumor cells and circulating tumor DNA
    • Haber DA, Velculescu VE (2014) Blood-based analyses of cancer: Circulating tumor cells and circulating tumor DNA. Cancer Discov 4(6):650-661.
    • (2014) Cancer Discov , vol.4 , Issue.6 , pp. 650-661
    • Haber, D.A.1    Velculescu, V.E.2
  • 21
    • 84860601923 scopus 로고    scopus 로고
    • Single cell profiling of circulating tumor cells: Transcriptional heterogeneity and diversity from breast cancer cell lines
    • Powell AA, et al. (2012) Single cell profiling of circulating tumor cells: Transcriptional heterogeneity and diversity from breast cancer cell lines. PLoS One 7(5):e33788.
    • (2012) PLoS One , vol.7 , Issue.5 , pp. e33788
    • Powell, A.A.1
  • 22
    • 84876948946 scopus 로고    scopus 로고
    • Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer
    • Chen CL, et al. (2013) Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer. Prostate 73(8):813-826.
    • (2013) Prostate , vol.73 , Issue.8 , pp. 813-826
    • Chen, C.L.1
  • 23
    • 79952232216 scopus 로고    scopus 로고
    • Global cancer statistics
    • Jemal A, et al. (2011) Global cancer statistics. CA Cancer J Clin 61(2):69-90.
    • (2011) CA Cancer J Clin , vol.61 , Issue.2 , pp. 69-90
    • Jemal, A.1
  • 24
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • National Cancer Institute of Canada Clinical Trials Group
    • Shepherd FA, et al.; National Cancer Institute of Canada Clinical Trials Group (2005) Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 353(2):123-132.
    • (2005) N Engl J Med , vol.353 , Issue.2 , pp. 123-132
    • Shepherd, F.A.1
  • 25
    • 84918804764 scopus 로고    scopus 로고
    • First-line crizotinib versus chemotherapy in ALK-positive lung cancer
    • PROFILE 1014 Investigators
    • Solomon BJ, et al.; PROFILE 1014 Investigators (2014) First-line crizotinib versus chemotherapy in ALK-positive lung cancer. N Engl J Med 371(23):2167-2177.
    • (2014) N Engl J Med , vol.371 , Issue.23 , pp. 2167-2177
    • Solomon, B.J.1
  • 26
    • 84897077889 scopus 로고    scopus 로고
    • Discriminating cellular heterogeneity using microwell-based RNA cytometry
    • Dimov IK, et al. (2014) Discriminating cellular heterogeneity using microwell-based RNA cytometry. Nat Commun 5:3451.
    • (2014) Nat Commun , vol.5 , pp. 3451
    • Dimov, I.K.1
  • 27
    • 84988826306 scopus 로고    scopus 로고
    • Dual transcript and protein quantification in a massive single cell array
    • Park SM, et al. (2016) Dual transcript and protein quantification in a massive single cell array. Lab Chip 16(19):3682-3688.
    • (2016) Lab Chip , vol.16 , Issue.19 , pp. 3682-3688
    • Park, S.M.1
  • 28
    • 0035126283 scopus 로고    scopus 로고
    • Purification and characterization of PCR-inhibitory components in blood cells
    • Al-Soud WA, Radström P (2001) Purification and characterization of PCR-inhibitory components in blood cells. J Clin Microbiol 39(2):485-493.
    • (2001) J Clin Microbiol , vol.39 , Issue.2 , pp. 485-493
    • Al-Soud, W.A.1    Radström, P.2
  • 29
    • 84891354380 scopus 로고    scopus 로고
    • Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients
    • Ni X, et al. (2013) Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients. Proc Natl Acad Sci USA 110(52):21083-21088.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.52 , pp. 21083-21088
    • Ni, X.1
  • 30
    • 0642311916 scopus 로고    scopus 로고
    • Quantification of free circulating DNA as a diagnostic marker in lung cancer
    • Sozzi G, et al. (2003) Quantification of free circulating DNA as a diagnostic marker in lung cancer. J Clin Oncol 21(21):3902-3908.
    • (2003) J Clin Oncol , vol.21 , Issue.21 , pp. 3902-3908
    • Sozzi, G.1
  • 31
    • 62449250134 scopus 로고    scopus 로고
    • MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors
    • Kubo T, et al. (2009) MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors. Int J Cancer 124(8):1778-1784.
    • (2009) Int J Cancer , vol.124 , Issue.8 , pp. 1778-1784
    • Kubo, T.1
  • 32
    • 0027633237 scopus 로고
    • Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells
    • Tsao M-S, et al. (1993) Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells. Cell Growth Differ 4(7):571-579.
    • (1993) Cell Growth Differ , vol.4 , Issue.7 , pp. 571-579
    • Tsao, M.-S.1
  • 33
    • 77958198161 scopus 로고    scopus 로고
    • Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: Immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations
    • Kato Y, et al. (2010) Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: Immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations. J Thorac Oncol 5(10):1551-1558.
    • (2010) J Thorac Oncol , vol.5 , Issue.10 , pp. 1551-1558
    • Kato, Y.1
  • 34
    • 84896498173 scopus 로고    scopus 로고
    • Universal marker and detection tool for human sarcoma circulating tumor cells
    • Satelli A, et al. (2014) Universal marker and detection tool for human sarcoma circulating tumor cells. Cancer Res 74(6):1645-1650.
    • (2014) Cancer Res , vol.74 , Issue.6 , pp. 1645-1650
    • Satelli, A.1
  • 35
    • 79955045007 scopus 로고    scopus 로고
    • Evaluation and prognostic significance of circulating tumor cells in patients with non-small-cell lung cancer
    • Krebs MG, et al. (2011) Evaluation and prognostic significance of circulating tumor cells in patients with non-small-cell lung cancer. J Clin Oncol 29(12):1556-1563.
    • (2011) J Clin Oncol , vol.29 , Issue.12 , pp. 1556-1563
    • Krebs, M.G.1
  • 36
    • 55249109939 scopus 로고    scopus 로고
    • The prognostic impact of NF-kappaB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer
    • Al-Saad S, et al. (2008) The prognostic impact of NF-kappaB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer. Br J Cancer 99(9):1476-1483.
    • (2008) Br J Cancer , vol.99 , Issue.9 , pp. 1476-1483
    • Al-Saad, S.1
  • 37
    • 62549152644 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer
    • Jiang F, et al. (2009) Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer. Mol Cancer Res 7(3):330-338.
    • (2009) Mol Cancer Res , vol.7 , Issue.3 , pp. 330-338
    • Jiang, F.1
  • 38
    • 84899673997 scopus 로고    scopus 로고
    • Toward integrated molecular diagnostic system (iMDx): Principles and applications
    • Park SM, Sabour AF, Son JH, Lee SH, Lee LP (2014) Toward integrated molecular diagnostic system (iMDx): Principles and applications. IEEE Trans Biomed Eng 61(5):1506-1521.
    • (2014) IEEE Trans Biomed Eng , vol.61 , Issue.5 , pp. 1506-1521
    • Park, S.M.1    Sabour, A.F.2    Son, J.H.3    Lee, S.H.4    Lee, L.P.5
  • 39
    • 13844317894 scopus 로고    scopus 로고
    • EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
    • Kobayashi S, et al. (2005) EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 352(8):786-792.
    • (2005) N Engl J Med , vol.352 , Issue.8 , pp. 786-792
    • Kobayashi, S.1
  • 40
    • 84962222188 scopus 로고    scopus 로고
    • Detection of T790M, the acquired resistance EGFR mutation, by tumor biopsy versus noninvasive blood-based analyses
    • Sundaresan TK, et al. (2016) Detection of T790M, the acquired resistance EGFR mutation, by tumor biopsy versus noninvasive blood-based analyses. Clin Cancer Res 22(5):1103-1110.
    • (2016) Clin Cancer Res , vol.22 , Issue.5 , pp. 1103-1110
    • Sundaresan, T.K.1
  • 41
    • 84903218109 scopus 로고    scopus 로고
    • An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
    • Newman AM, et al. (2014) An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nat Med 20(5):548-554.
    • (2014) Nat Med , vol.20 , Issue.5 , pp. 548-554
    • Newman, A.M.1
  • 42
    • 84864880991 scopus 로고    scopus 로고
    • Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
    • Ramsköld D, et al. (2012) Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells. Nat Biotechnol 30(8):777-782.
    • (2012) Nat Biotechnol , vol.30 , Issue.8 , pp. 777-782
    • Ramsköld, D.1
  • 43
    • 84900333051 scopus 로고    scopus 로고
    • Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
    • Lohr JG, et al. (2014) Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nat Biotechnol 32(5):479-484.
    • (2014) Nat Biotechnol , vol.32 , Issue.5 , pp. 479-484
    • Lohr, J.G.1
  • 44
    • 27544487984 scopus 로고    scopus 로고
    • Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer
    • Miyazu YM, et al. (2005) Telomerase expression in noncancerous bronchial epithelia is a possible marker of early development of lung cancer. Cancer Res 65(21):9623-9627.
    • (2005) Cancer Res , vol.65 , Issue.21 , pp. 9623-9627
    • Miyazu, Y.M.1
  • 45
    • 11144356221 scopus 로고    scopus 로고
    • Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
    • Lantuejoul S, et al. (2004) Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours. Br J Cancer 90(6):1222-1229.
    • (2004) Br J Cancer , vol.90 , Issue.6 , pp. 1222-1229
    • Lantuejoul, S.1
  • 46
    • 33646851581 scopus 로고    scopus 로고
    • Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer
    • Zhu CQ, et al. (2006) Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. Br J Cancer 94(10):1452-1459.
    • (2006) Br J Cancer , vol.94 , Issue.10 , pp. 1452-1459
    • Zhu, C.Q.1
  • 47
    • 0041386273 scopus 로고    scopus 로고
    • The diagnostic and prognostic relevance of human telomerase reverse transcriptase mRNA expression detected in situ in patients with nonsmall cell lung carcinoma
    • Fujita Y, et al. (2003) The diagnostic and prognostic relevance of human telomerase reverse transcriptase mRNA expression detected in situ in patients with nonsmall cell lung carcinoma. Cancer 98(5):1008-1013.
    • (2003) Cancer , vol.98 , Issue.5 , pp. 1008-1013
    • Fujita, Y.1
  • 48
    • 33750283181 scopus 로고    scopus 로고
    • Clinical usefulness of serum telomerase reverse transcriptase (hTERT) mRNA and epidermal growth factor receptor (EGFR) mRNA as a novel tumor marker for lung cancer
    • Miura N, et al. (2006) Clinical usefulness of serum telomerase reverse transcriptase (hTERT) mRNA and epidermal growth factor receptor (EGFR) mRNA as a novel tumor marker for lung cancer. Cancer Sci 97(12):1366-1373.
    • (2006) Cancer Sci , vol.97 , Issue.12 , pp. 1366-1373
    • Miura, N.1
  • 49
    • 0031667559 scopus 로고    scopus 로고
    • Differential expression of Met/hepatocyte growth factor receptor in subtypes of non-small cell lung cancers
    • Tsao M-S, et al. (1998) Differential expression of Met/hepatocyte growth factor receptor in subtypes of non-small cell lung cancers. Lung Cancer 20(1):1-16.
    • (1998) Lung Cancer , vol.20 , Issue.1 , pp. 1-16
    • Tsao, M.-S.1
  • 50
    • 84997909291 scopus 로고    scopus 로고
    • C-MET as a potential therapeutic target and biomarker in cancer
    • Sierra JR, Tsao M-S (2011) c-MET as a potential therapeutic target and biomarker in cancer. Ther Adv Med Oncol 3(1, Suppl):S21-S35.
    • (2011) Ther Adv Med Oncol , vol.3 , Issue.1 , pp. S21-S35
    • Sierra, J.R.1    Tsao, M.-S.2
  • 51
    • 33746647733 scopus 로고    scopus 로고
    • Combined detection of CEA, CK-19 and c-met mRNAs in peripheral blood: A highly sensitive panel for potential molecular diagnosis of non-small cell lung cancer
    • Sheu C-C, et al. (2006) Combined detection of CEA, CK-19 and c-met mRNAs in peripheral blood: A highly sensitive panel for potential molecular diagnosis of non-small cell lung cancer. Oncology 70(3):203-211.
    • (2006) Oncology , vol.70 , Issue.3 , pp. 203-211
    • Sheu, C.-C.1
  • 52
    • 24944468127 scopus 로고    scopus 로고
    • Overexpression of circulating c-met messenger RNA is significantly correlated with nodal stage and early recurrence in non-small cell lung cancer
    • Cheng T-L, et al. (2005) Overexpression of circulating c-met messenger RNA is significantly correlated with nodal stage and early recurrence in non-small cell lung cancer. Chest 128(3):1453-1460.
    • (2005) Chest , vol.128 , Issue.3 , pp. 1453-1460
    • Cheng, T.-L.1
  • 54
    • 64249106622 scopus 로고    scopus 로고
    • Microfabricated magnetic sifter for high-throughput and high-gradient magnetic separation
    • Earhart CM, Wilson RJ, White RL, Pourmand N, Wang SX (2009) Microfabricated magnetic sifter for high-throughput and high-gradient magnetic separation. J Magn Magn Mater 321(10):1436-1439.
    • (2009) J Magn Magn Mater , vol.321 , Issue.10 , pp. 1436-1439
    • Earhart, C.M.1    Wilson, R.J.2    White, R.L.3    Pourmand, N.4    Wang, S.X.5
  • 55
    • 84864285223 scopus 로고    scopus 로고
    • RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis
    • Yu M, et al. (2012) RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature 487(7408):510-513.
    • (2012) Nature , vol.487 , Issue.7408 , pp. 510-513
    • Yu, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.