Nanostructure embedded microchips for detection, isolation, and characterization of circulating tumor cells

Accounts of Chemical Research

Volumn 47, Issue 10, 2014, Pages 2941-2950

  Lin, Millicent ^a,b   Chen, Jie Fu ^b   Lu, Yi Tsung ^b   Zhang, Yang ^b   Song, Jinzhao ^b   Hou, Shuang ^b   Ke, Zunfu ^a   Tseng, Hsian Rong ^b  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOMATERIAL;

CELL SEPARATION; CHEMISTRY; DEVICES; HUMAN; MICROFLUIDIC ANALYSIS; PATHOLOGY; PROCEDURES; TUMOR EMBOLISM;

CELL SEPARATION; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; NANOSTRUCTURES; NEOPLASTIC CELLS, CIRCULATING;

EID: 84908115631     PISSN: 00014842     EISSN: 15204898     Source Type: Journal    
DOI: 10.1021/ar5001617     Document Type: Article

References (47)

1. Kaiser, J. Cancer"s circulation problem Science 2010, 327, 1072-1074
2. Criscitiello, C.; Sotiriou, C.; Ignatiadis, M. Circulating tumor cells and emerging blood biomarkers in breast cancer Curr. Opin. Oncol. 2010, 22, 552-558
3. van de Stolpe, A.; Pantel, K.; Sleijfer, S.; Terstappen, L. W.; den Toonder, J. M. Circulating tumor cell isolation and diagnostics: Toward routine clinical use Cancer Res. 2011, 71, 5955-5960
4. Cristofanilli, M.; Budd, G. T.; Ellis, M. J.; Stopeck, A.; Matera, J.; Miller, M. C.; Reuben, J. M.; Doyle, G. V.; Allard, W. J.; Terstappen, L. W.; Hayes, D. F. Circulating tumor cells, disease progression, and survival in metastatic breast cancer N. Engl. J. Med. 2004, 351, 781-791
5. Shaffer, D. R.; Leversha, M. A.; Danila, D. C.; Lin, O.; Gonzalez-Espinoza, R.; Gu, B.; Anand, A.; Smith, K.; Maslak, P.; Doyle, G. V.; Terstappen, L. W.; Lilja, H.; Heller, G.; Fleisher, M.; Scher, H. I. Circulating tumor cell analysis in patients with progressive castration-resistant prostate cancer Clin. Cancer Res. 2007, 13, 2023-2029
6. Talasaz, A. H.; Powell, A. A.; Huber, D. E.; Berbee, J. G.; Roh, K. H.; Yu, W.; Xiao, W. Z.; Davis, M. M.; Pease, R. F.; Mindrinos, M. N.; Jeffrey, S. S.; Davis, R. W. Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device Proc. Natl. Acad. Sci. U.S.A. 2009, 106, 3970-3975
7. Harb, W.; Fan, A.; Tran, T.; Danila, D. C.; Keys, D.; Schwartz, M.; Ionescu-Zanetti, C. Mutational analysis of circulating tumor cells using a novel microfluidic collection device and qPCR assay Transl. Oncol. 2013, 6, 528
8. Casavant, B. P.; Guckenberger, D. J.; Berry, S. M.; Tokar, J. T.; Lang, J. M.; Beebe, D. J. The VerIFAST: An integrated method for cell isolation and extracellular/intracellular staining Lab Chip 2013, 13, 391-396
9. Ozkumur, E.; Shah, A. M.; Ciciliano, J. C.; Emmink, B. L.; Miyamoto, D. T.; Brachtel, E.; Yu, M.; Chen, P. I.; Morgan, B.; Trautwein, J.; Kimura, A.; Sengupta, S.; Stott, S. L.; Karabacak, N. M.; Barber, T. A.; Walsh, J. R.; Smith, K.; Spuhler, P. S.; Sullivan, J. P.; Lee, R. J.; Ting, D. T.; Luo, X.; Shaw, A. T.; Bardia, A.; Sequist, L. V.; Louis, D. N.; Maheswaran, S.; Kapur, R.; Haber, D. A.; Toner, M. Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells Sci. Transl. Med. 2013, 5 179ra47
10. He, W.; Wang, H.; Hartmann, L. C.; Cheng, J. X.; Low, P. S. In vivo quantitation of rare circulating tumor cells by multiphoton intravital flow cytometry Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 11760-11765
11. Zhao, M.; Schiro, P. G.; Kuo, J. S.; Koehler, K. M.; Sabath, D. E.; Popov, V.; Feng, Q.; Chiu, D. T. An automated high-throughput counting method for screening circulating tumor cells in peripheral blood Anal. Chem. 2013, 85, 2465-2471
12. Nagrath, S.; Sequist, L. V.; Maheswaran, S.; Bell, D. W.; Irimia, D.; Ulkus, L.; Smith, M. R.; Kwak, E. L.; Digumarthy, S.; Muzikansky, A.; Ryan, P.; Balis, U. J.; Tompkins, R. G.; Haber, D. A.; Toner, M. Isolation of rare circulating tumour cells in cancer patients by microchip technology Nature 2007, 450, 1235-1239
13. Adams, A. A.; Okagbare, P. I.; Feng, J.; Hupert, M. L.; Patterson, D.; Gottert, J.; McCarley, R. L.; Nikitopoulos, D.; Murphy, M. C.; Soper, S. A. Highly efficient circulating tumor cell isolation from whole blood and label-free enumeration using polymer-based microfluidics with an integrated conductivity sensor J. Am. Chem. Soc. 2008, 130, 8633-8641
14. Stott, S. L.; Hsu, C. H.; Tsukrov, D. I.; Yu, M.; Miyamoto, D. T.; Waltman, B. A.; Rothenberg, S. M.; Shah, A. M.; Smas, M. E.; Korir, G. K.; Floyd, F. P., Jr.; Gilman, A. J.; Lord, J. B.; Winokur, D.; Springer, S.; Irimia, D.; Nagrath, S.; Sequist, L. V.; Lee, R. J.; Isselbacher, K. J.; Maheswaran, S.; Haber, D. A.; Toner, M. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 18392-18397
15. Tan, S. J.; Yobas, L.; Lee, G. Y.; Ong, C. N.; Lim, C. T. Microdevice for the isolation and enumeration of cancer cells from blood Biomed. Microdevices 2009, 11, 883-892
16. Lecharpentier, A.; Vielh, P.; Perez-Moreno, P.; Planchard, D.; Soria, J. C.; Farace, F. Detection of circulating tumour cells with a hybrid (epithelial/mesenchymal) phenotype in patients with metastatic non-small cell lung cancer Br. J. Cancer 2011, 105, 1338-1341
17. Pantel, K.; Brakenhoff, R. H.; Brandt, B. Detection, clinical relevance and specific biological properties of disseminating tumour cells Nat. Rev. Cancer 2008, 8, 329-340
18. Fan, Z. H.; Beebe, D. J. Lab on a chip and circulating tumor cells Lab Chip 2014, 14, 12-13
19. Yu, M.; Bardia, A.; Aceto, N.; Bersani, F.; Madden, M. W.; Donaldson, M. C.; Desai, R.; Zhu, H.; Comaills, V.; Zheng, Z.; Wittner, B. S.; Stojanov, P.; Brachtel, E.; Sgroi, D.; Kapur, R.; Shioda, T.; Ting, D. T.; Ramaswamy, S.; Getz, G.; Iafrate, A. J.; Benes, C.; Toner, M.; Maheswaran, S.; Haber, D. A. Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility Science 2014, 345, 216-220
20. Lohr, J. G.; Adalsteinsson, V. A.; Cibulskis, K.; Choudhury, A. D.; Rosenberg, M.; Cruz-Gordillo, P.; Francis, J. M.; Zhang, C. Z.; Shalek, A. K.; Satija, R.; Trombetta, J. J.; Lu, D.; Tallapragada, N.; Tahirova, N.; Kim, S.; Blumenstiel, B.; Sougnez, C.; Lowe, A.; Wong, B.; Auclair, D.; Van Allen, E. M.; Nakabayashi, M.; Lis, R. T.; Lee, G. S.; Li, T.; Chabot, M. S.; Ly, A.; Taplin, M. E.; Clancy, T. E.; Loda, M.; Regev, A.; Meyerson, M.; Hahn, W. C.; Kantoff, P. W.; Golub, T. R.; Getz, G.; Boehm, J. S.; Love, J. C. Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer Nat. Biotechnol. 2014, 32, 479-484
21. Wang, S.; Wang, H.; Jiao, J.; Chen, K. J.; Owens, G. E.; Kamei, K.; Sun, J.; Sherman, D. J.; Behrenbruch, C. P.; Wu, H.; Tseng, H. R. Three-dimensional nanostructured substrates toward efficient capture of circulating tumor cells Angew. Chem., Int. Ed. 2009, 48, 8970-8973
22. Sekine, J.; Luo, S. C.; Wang, S.; Zhu, B.; Tseng, H. R.; Yu, H. H. Functionalized conducting polymer nanodots for enhanced cell capturing: the synergistic effect of capture agents and nanostructures Adv. Mater. 2011, 23, 4788-4792
23. 2 nanofiber-based cell capture assay for detecting circulating tumor cells from colorectal and gastric cancer patients Adv. Mater. 2012, 24, 2756-2760
24. Hsiao, Y.-S.; Luo, S.-C.; Hou, S.; Zhu, B.; Sekine, J.; Kuo, C.-W.; Chueh, D.-Y.; Yu, H.-h.; Tseng, H.-R.; Chen, P. 3D bioelectronic interface: Capturing circulating tumor cells onto conducting polymer-based micro/nanorod arrays with chemical and topographical control Small 2014, 10, 3012-3017
25. Wang, S.; Liu, K.; Liu, J.; Yu, Z. T.; Xu, X.; Zhao, L.; Lee, T.; Lee, E. K.; Reiss, J.; Lee, Y. K.; Chung, L. W.; Huang, J.; Rettig, M.; Seligson, D.; Duraiswamy, K. N.; Shen, C. K.; Tseng, H. R. Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers Angew. Chem., Int. Ed. 2011, 50, 3084-3088
26. Lu, Y. T.; Zhao, L.; Shen, Q.; Garcia, M. A.; Wu, D.; Hou, S.; Song, M.; Xu, X.; Ouyang, W. H.; Ouyang, W. W.; Lichterman, J.; Luo, Z.; Xuan, X.; Huang, J.; Chung, L. W.; Rettig, M.; Tseng, H. R.; Shao, C.; Posadas, E. M. NanoVelcro chip for CTC enumeration in prostate cancer patients Methods 2013, 64, 144-152
27. Shen, Q.; Xu, L.; Zhao, L.; Wu, D.; Fan, Y.; Zhou, Y.; Ouyang, W. H.; Xu, X.; Zhang, Z.; Song, M.; Lee, T.; Garcia, M. A.; Xiong, B.; Hou, S.; Tseng, H. R.; Fang, X. Specific capture and release of circulating tumor cells using aptamer-modified nanosubstrates Adv. Mater. 2013, 25, 2368-2373
28. Hou, S.; Zhao, L.; Shen, Q.; Yu, J.; Ng, C.; Kong, X.; Wu, D.; Song, M.; Shi, X.; Xu, X.; OuYang, W. H.; He, R.; Zhao, X. Z.; Lee, T.; Brunicardi, F. C.; Garcia, M. A.; Ribas, A.; Lo, R. S.; Tseng, H. R. Polymer nanofiber-embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells Angew. Chem., Int. Ed. 2013, 52, 3379-3383
29. Zhao, L.; Lu, Y. T.; Li, F.; Wu, K.; Hou, S.; Yu, J.; Shen, Q.; Wu, D.; Song, M.; Ouyang, W. H.; Luo, Z.; Lee, T.; Fang, X.; Shao, C.; Xu, X.; Garcia, M. A.; Chung, L. W.; Rettig, M.; Tseng, H. R.; Posadas, E. M. High-purity prostate circulating tumor cell isolation by a polymer nanofiber-embedded microchip for whole exome sequencing Adv. Mater. 2013, 25, 2897-2902
30. Hou, S.; Zhao, H.; Zhao, L.; Shen, Q.; Wei, K. S.; Suh, D. Y.; Nakao, A.; Garcia, M. A.; Song, M.; Lee, T.; Xiong, B.; Luo, S. C.; Tseng, H. R.; Yu, H. H. Capture and stimulated release of circulating tumor cells on polymer-grafted silicon nanostructures Adv. Mater. 2013, 25, 1547-1551
31. Bettinger, C. J.; Langer, R.; Borenstein, J. T. Engineering substrate topography at the micro- and nanoscale to control cell function Angew. Chem., Int. Ed. 2009, 48, 5406-5415
32. Liu, X.; Wang, S. Three-dimensional nano-biointerface as a new platform for guiding cell fate Chem. Soc. Rev. 2014, 43, 2385-2401
33. Saracino, G. A. A.; Cigognini, D.; Silva, D.; Caprini, A.; Gelain, F. Nanomaterials design and tests for neural tissue engineering Chem. Soc. Rev. 2013, 42, 225-262
34. Fischer, K. E.; Aleman, B. J.; Tao, S. L.; Hugh Daniels, R.; Li, E. M.; Bunger, M. D.; Nagaraj, G.; Singh, P.; Zettl, A.; Desai, T. A. Biomimetic nanowire coatings for next generation adhesive drug delivery systems Nano Lett. 2009, 9, 716-720
35. Lee, H.; Jang, Y.; Seo, J.; Nam, J.-M.; Char, K. Nanoparticle-functionalized polymer platform for controlling metastatic cancer cell adhesion, shape, and motility ACS Nano 2011, 5, 5444-5456
36. Park, G.-S.; Kwon, H.; Kwak, D. W.; Park, S. Y.; Kim, M.; Lee, J.-H.; Han, H.; Heo, S.; Li, X. S.; Lee, J. H.; Kim, Y. H.; Lee, J.-G.; Yang, W.; Cho, H. Y.; Kim, S. K.; Kim, K. Full surface embedding of gold clusters on silicon nanowires for efficient capture and photothermal therapy of circulating tumor cells Nano Lett. 2012, 12, 1638-1642
37. Banerjee, S. S.; Paul, D.; Bhansali, S. G.; Aher, N. D.; Jalota-Badhwar, A.; Khandare, J. Enhancing surface interactions with colon cancer cells on a transferrin-conjugated 3D nanostructured substrate Small 2012, 8, 1657-1663
38. Liu, X.; Chen, L.; Liu, H.; Yang, G.; Zhang, P.; Han, D.; Wang, S.; Jiang, L. Bio-inspired soft polystyrene nanotube substrate for rapid and highly efficient breast cancer-cell capture NPG Asia Mater. 2013, 5, e63
39. 2 nanoparticle-based cell immunoassay for circulating tumor cells capture and identification from cancer patients Biomed. Microdevices 2013, 15, 617-626
40. Zhang, P.; Chen, L.; Xu, T.; Liu, H.; Liu, X.; Meng, J.; Yang, G.; Jiang, L.; Wang, S. Programmable fractal nanostructured interfaces for specific recognition and electrochemical release of cancer cells Adv. Mater. 2013, 25, 3566-3570
41. Benson, K.; Prasetyanto, E. A.; Galla, H.-J.; Kehr, N. S. Self-assembled monolayers of bifunctional periodic mesoporous organosilicas for cell adhesion and cellular patterning Soft Matter 2012, 8, 10845-10852
42. Kumeria, T.; Kurkuri, M. D.; Diener, K. R.; Parkinson, L.; Losic, D. Label-free reflectometric interference microchip biosensor based on nanoporous alumina for detection of circulating tumour cells Biosens. Bioelectron. 2012, 35, 167-173
43. Stroock, A. D.; Dertinger, S. K.; Ajdari, A.; Mezic, I.; Stone, H. A.; Whitesides, G. M. Chaotic mixer for microchannels Science 2002, 295, 647-651
44. Sun, J.; Masterman-Smith, M. D.; Graham, N. A.; Jiao, J.; Mottahedeh, J.; Laks, D. R.; Ohashi, M.; DeJesus, J.; Kamei, K.; Lee, K. B.; Wang, H.; Yu, Z. T.; Lu, Y. T.; Hou, S.; Li, K.; Liu, M.; Zhang, N.; Wang, S.; Angenieux, B.; Panosyan, E.; Samuels, E. R.; Park, J.; Williams, D.; Konkankit, V.; Nathanson, D.; van Dam, R. M.; Phelps, M. E.; Wu, H.; Liau, L. M.; Mischel, P. S.; Lazareff, J. A.; Kornblum, H. I.; Yong, W. H.; Graeber, T. G.; Tseng, H. R. A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens Cancer Res. 2010, 70, 6128-6138
45. Fang, X.; Tan, W. Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach Acc. Chem. Res. 2010, 43, 48-57
46. Chen, W.; Weng, S.; Zhang, F.; Allen, S.; Li, X.; Bao, L.; Lam, R. H.; Macoska, J. A.; Merajver, S. D.; Fu, J. Nanoroughened surfaces for efficient capture of circulating tumor cells without using capture antibodies ACS Nano 2013, 7, 566-575
47. Okano, T.; Yamada, N.; Okuhara, M.; Sakai, H.; Sakurai, Y. Mechanism of cell detechment from temperature-modulated hydrophilic-hydrophobic polymer surfaces Biomaterials 1995, 16, 297-303