메뉴 건너뛰기




Volumn 5, Issue , 2014, Pages

Discriminating cellular heterogeneity using microwell-based RNA cytometry

Author keywords

[No Author keywords available]

Indexed keywords

RNA; MESSENGER RNA;

EID: 84897077889     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4451     Document Type: Article
Times cited : (39)

References (37)
  • 1
    • 33747132429 scopus 로고    scopus 로고
    • Biology of ccr5 and its role in hiv infection and treatment
    • Lederman, M., Penn-Nicholson, A., Cho, M. & Mosier, D. Biology of ccr5 and its role in hiv infection and treatment. JAMA 296, 815-826 (2006).
    • (2006) JAMA , vol.296 , pp. 815-826
    • Lederman, M.1    Penn-Nicholson, A.2    Cho, M.3    Mosier, D.4
  • 2
    • 0032562720 scopus 로고    scopus 로고
    • Visualization of single rna transcripts in situ
    • Femino, A. M., Fay, F. S., Fogarty, K. & Singer, R. H. Visualization of single rna transcripts in situ. Science 280, 585-590 (1998).
    • (1998) Science , vol.280 , pp. 585-590
    • Femino, A.M.1    Fay, F.S.2    Fogarty, K.3    Singer, R.H.4
  • 3
    • 67650319009 scopus 로고    scopus 로고
    • Single-molecule approaches to stochastic gene expression
    • Raj, A. & van Oudenaarden, A. Single-molecule approaches to stochastic gene expression. Annu. Rev. Biophys. 38, 255-270 (2009).
    • (2009) Annu. Rev. Biophys. , vol.38 , pp. 255-270
    • Raj, A.1    Van Oudenaarden, A.2
  • 4
    • 83255177150 scopus 로고    scopus 로고
    • Single-cell dissection of transcriptional heterogeneity in human colon tumors
    • Dalerba, P. et al. Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat. Biotech. 29, 1120-1127 (2011).
    • Nat. Biotech. , vol.29 , pp. 1120-1127
    • Dalerba, P.1
  • 5
    • 57449093576 scopus 로고    scopus 로고
    • High-throughput quantitative polymerase chain reaction in picoliter droplets
    • Kiss, M. M. et al. High-throughput quantitative polymerase chain reaction in picoliter droplets. Anal. Chem. 80, 8975-8981 (2008).
    • (2008) Anal. Chem. , vol.80 , pp. 8975-8981
    • Kiss, M.M.1
  • 6
    • 0348251333 scopus 로고    scopus 로고
    • A massively parallel PicoTiterPlatet based platform for discrete picoliter-scale polymerase chain reactions
    • Leamon, J. H. et al. A massively parallel PicoTiterPlatet based platform for discrete picoliter-scale polymerase chain reactions. Electrophoresis 24, 3769-3777 (2003).
    • (2003) Electrophoresis , vol.24 , pp. 3769-3777
    • Leamon, J.H.1
  • 7
    • 29244468315 scopus 로고    scopus 로고
    • Single-cell microarray for analyzing cellular response
    • Yamamura, S. et al. Single-cell microarray for analyzing cellular response. Anal. Chem. 77, 8050-8056 (2005).
    • (2005) Anal. Chem. , vol.77 , pp. 8050-8056
    • Yamamura, S.1
  • 8
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • Elowitz, M. B., Levine, A. J., Siggia, E. D. & Swain, P. S. Stochastic gene expression in a single cell. Science 297, 1183-1186 (2002).
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3    Swain, P.S.4
  • 9
    • 0037213715 scopus 로고    scopus 로고
    • Gene expression and the myth of the average cell
    • Levsky, J. M. & Singer, R. H. Gene expression and the myth of the average cell. Trends Cell Biol. 13, 4-6 (2003).
    • (2003) Trends Cell Biol , vol.13 , pp. 4-6
    • Levsky, J.M.1    Singer, R.H.2
  • 10
    • 37349044981 scopus 로고    scopus 로고
    • A microfluidic processor for gene expression profiling of single human embryonic stem cells
    • Zhong, J. F. et al. A microfluidic processor for gene expression profiling of single human embryonic stem cells. Lab. Chip. 8, 68-74 (2008).
    • (2008) Lab. Chip. , vol.8 , pp. 68-74
    • Zhong, J.F.1
  • 11
    • 25844433114 scopus 로고    scopus 로고
    • Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels
    • Bengtsson, M., Stahlberg, A., Rorsman, P. & Kubista, M. Gene expression profiling in single cells from the pancreatic islets of Langerhans reveals lognormal distribution of mRNA levels. Genome Res. 15, 1388-1392 (2005).
    • (2005) Genome Res , vol.15 , pp. 1388-1392
    • Bengtsson, M.1    Stahlberg, A.2    Rorsman, P.3    Kubista, M.4
  • 12
    • 78751582939 scopus 로고    scopus 로고
    • Hematopoietic stem cell: Self-renewal versus differentiation. WIREs Syst
    • Seita, J. & Weissman, I. L. Hematopoietic stem cell: self-renewal versus differentiation. WIREs Syst. Biol. Med. 2, 640-653 (2010).
    • (2010) Biol. Med. , vol.2 , pp. 640-653
    • Seita, J.1    Weissman, I.L.2
  • 13
    • 33750126450 scopus 로고    scopus 로고
    • Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment
    • McKenzie, J. L., Gan, O. I., Doedens, M., Wang, J. C. Y. & Dick, J. E. Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment. Nat. Immunol. 7, 1225-1233 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 1225-1233
    • McKenzie, J.L.1    Gan, O.I.2    Doedens, M.3    Wang, J.C.Y.4    Dick, J.E.5
  • 14
    • 34547692981 scopus 로고    scopus 로고
    • Long-term propagation of distinct hematopoietic differentiation programs in vivo
    • Dykstra, B. et al. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell stem cell 1, 218-229 (2007).
    • (2007) Cell Stem Cell , vol.1 , pp. 218-229
    • Dykstra, B.1
  • 15
    • 77950418688 scopus 로고    scopus 로고
    • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    • Beerman, I. et al. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. PNAS 107, 5465-5470 (2010).
    • (2010) PNAS , vol.107 , pp. 5465-5470
    • Beerman, I.1
  • 16
    • 77953512588 scopus 로고    scopus 로고
    • Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
    • Morita, Y., Ema, H. & Nakauchi, H. Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J. Exp. Med. 207, 1173-1182 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 1173-1182
    • Morita, Y.1    Ema, H.2    Nakauchi, H.3
  • 17
    • 33644781621 scopus 로고    scopus 로고
    • The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets
    • Sieburg, H. B. et al. The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets. Blood 107, 2311-2316 (2006).
    • (2006) Blood , vol.107 , pp. 2311-2316
    • Sieburg, H.B.1
  • 18
    • 47049099198 scopus 로고    scopus 로고
    • A new mechanism for the aging of hematopoietic stem cells: Aging changes the clonal composition of the stem cell compartment but not individual stem cells
    • Cho, R. H., Sieburg, H. B. & Muller-Sieburg, C. E. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood 111, 5553-5561 (2008).
    • (2008) Blood , vol.111 , pp. 5553-5561
    • Cho, R.H.1    Sieburg, H.B.2    Muller-Sieburg, C.E.3
  • 19
    • 41349087734 scopus 로고    scopus 로고
    • CD150â̂ ' side population cells represent a functionally distinct population of long-term hematopoietic stem cells
    • Weksberg, D. C., Chambers, S. M., Boles, N. C. & Goodell, M. A. CD150â̂ ' side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood 111, 2444-2451 (2008).
    • (2008) Blood , vol.111 , pp. 2444-2451
    • Weksberg, D.C.1    Chambers, S.M.2    Boles, N.C.3    Goodell, M.A.4
  • 20
    • 67650587142 scopus 로고    scopus 로고
    • Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential
    • Kent, D. G. et al. Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. Blood 113, 6342-6350 (2009).
    • (2009) Blood , vol.113 , pp. 6342-6350
    • Kent, D.G.1
  • 21
    • 21544467270 scopus 로고    scopus 로고
    • Cell intrinsic alterations underlie hematopoietic stem cell aging
    • Rossi, D. J. et al. Cell intrinsic alterations underlie hematopoietic stem cell aging. PNAS 102, 9194-9199 (2005).
    • (2005) PNAS , vol.102 , pp. 9194-9199
    • Rossi, D.J.1
  • 22
    • 77449145533 scopus 로고    scopus 로고
    • Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-Î21
    • Challen, G. A., Boles, N. C., Chambers, S. M. & Goodell, M. A. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-Î21. Cell Stem Cell 6, 265-278 (2010).
    • (2010) Cell Stem Cell , vol.6 , pp. 265-278
    • Challen, G.A.1    Boles, N.C.2    Chambers, S.M.3    Goodell, M.A.4
  • 23
    • 79953178630 scopus 로고    scopus 로고
    • Nanolitre droplet array for real time reverse transcription polymerase chain reaction
    • Zhang, Y., Zhu, Y., Yao, B. & Fang, Q. Nanolitre droplet array for real time reverse transcription polymerase chain reaction. Lab. Chip. 11, 1545-1549 (2011).
    • (2011) Lab. Chip. , vol.11 , pp. 1545-1549
    • Zhang, Y.1    Zhu, Y.2    Yao, B.3    Fang, Q.4
  • 24
    • 0003007588 scopus 로고    scopus 로고
    • Quantitative RT-PCR: Rapid construction of templates for competitive amplification
    • Kephart, D. Quantitative RT-PCR: rapid construction of templates for competitive amplification. Promega Note 68, 20-23 (1998).
    • (1998) Promega Note , vol.68 , pp. 20-23
    • Kephart, D.1
  • 25
    • 0028900860 scopus 로고
    • An evaluation of competitor type and size for use in the determination of mRNA by competitive PCR
    • McCulloch, R. K., Choong, C. S. & Hurley, D. M. An evaluation of competitor type and size for use in the determination of mRNA by competitive PCR. Genome Res. 4, 219-226 (1995).
    • (1995) Genome Res , vol.4 , pp. 219-226
    • McCulloch, R.K.1    Choong, C.S.2    Hurley, D.M.3
  • 26
    • 0024352638 scopus 로고
    • Absolute mRNA quantification using the polymerase chain reaction (PCR). A novel approach by a PCR aided transcipt titration assay (PATTY)
    • Becker-Andre, M. & Hahlbrock, K. Absolute mRNA quantification using the polymerase chain reaction (PCR). A novel approach by a PCR aided transcipt titration assay (PATTY). Nucleic Acids Res. 17, 9437-9446 (1989).
    • (1989) Nucleic Acids Res , vol.17 , pp. 9437-9446
    • Becker-Andre, M.1    Hahlbrock, K.2
  • 27
    • 57149101122 scopus 로고    scopus 로고
    • Single-RNA counting reveals alternative modes of gene expression in yeast
    • Zenklusen, D., Larson, D. R. & Singer, R. H. Single-RNA counting reveals alternative modes of gene expression in yeast. Nat. Struct. Mol. Biol. 15, 1263-1271 (2008).
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 1263-1271
    • Zenklusen, D.1    Larson, D.R.2    Singer, R.H.3
  • 28
    • 77956116622 scopus 로고    scopus 로고
    • Massively parallel detection of gene expression in single cells using subnanolitre wells
    • Gong, Y., Ogunniyi, A. O. & Love, J. C. Massively parallel detection of gene expression in single cells using subnanolitre wells. Lab. Chip. 10, 2334-2337 (2010).
    • (2010) Lab. Chip. , vol.10 , pp. 2334-2337
    • Gong, Y.1    Ogunniyi, A.O.2    Love, J.C.3
  • 29
    • 79955961133 scopus 로고    scopus 로고
    • CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells
    • Robin, C., Ottersbach, K., Boisset, J.-C., Oziemlak, A. & Dzierzak, E. CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells. Blood 117, 5088-5091 (2011).
    • (2011) Blood , vol.117 , pp. 5088-5091
    • Robin, C.1    Ottersbach, K.2    Boisset, J.-C.3    Oziemlak, A.4    Dzierzak, E.5
  • 30
    • 84880790360 scopus 로고    scopus 로고
    • CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age
    • Gekas, C. & Graf, T. CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age. Blood 121, 4463-4472 (2013).
    • (2013) Blood , vol.121 , pp. 4463-4472
    • Gekas, C.1    Graf, T.2
  • 31
    • 34547120244 scopus 로고    scopus 로고
    • Extracting binary signals from microarray time-course data
    • Sahoo, D., Dill, D. L., Tibshirani, R. & Plevritis, S. K. Extracting binary signals from microarray time-course data. Nucleic Acids Res. 35, 3705-3712 (2007).
    • (2007) Nucleic Acids Res , vol.35 , pp. 3705-3712
    • Sahoo, D.1    Dill, D.L.2    Tibshirani, R.3    Plevritis, S.K.4
  • 32
    • 70450160004 scopus 로고    scopus 로고
    • Systems-level dynamic analyses of fate change in murine embryonic stem cells
    • Lu, R. et al. Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature 462, 358-362 (2009).
    • (2009) Nature , vol.462 , pp. 358-362
    • Lu, R.1
  • 33
    • 33745220278 scopus 로고    scopus 로고
    • Single-cell proteomic analysis of S. Cerevisiae reveals the architecture of biological noise
    • Newman, J. R. S. et al. Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature 441, 840-846 (2006).
    • (2006) Nature , vol.441 , pp. 840-846
    • Newman, J.R.S.1
  • 34
    • 39149086121 scopus 로고    scopus 로고
    • Stems cells and the pathways to aging and cancer
    • Rossi, D. J., Jamieson, C. H. M. & Weissman, I. L. Stems cells and the pathways to aging and cancer. Cell 132, 681-696 (2008).
    • (2008) Cell , vol.132 , pp. 681-696
    • Rossi, D.J.1    Jamieson, C.H.M.2    Weissman, I.L.3
  • 35
    • 67649939163 scopus 로고    scopus 로고
    • The increasing complexity of the cancer stem cell paradigm
    • Rosen, J. M. & Jordan, C. T. The increasing complexity of the cancer stem cell paradigm. Science 324, 1670-1673 (2009).
    • (2009) Science , vol.324 , pp. 1670-1673
    • Rosen, J.M.1    Jordan, C.T.2
  • 36
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot, T. et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367, 645-648 (1994).
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.