Size-selective collection of circulating tumor cells using Vortex technology

Lab on a Chip

Volumn 14, Issue 1, 2014, Pages 63-77

  Sollier, Elodie ^a,b   Go, Derek E ^a   Che, James ^a   Gossett, Daniel R ^a,c   O'Byrne, Sean ^a   Weaver, Westbrook M ^a,b   Kummer, Nicolas ^d   Rettig, Matthew ^d,e   Goldman, Jonathan ^e,f   Nickols, Nicholas ^d   McCloskey, Susan ^d,e   Kulkarni, Rajan P ^d   Di Carlo, Dino ^a,b,c,e  

^a Department of Civil and Environmental Engineering   (United States)

^b Vortex Biosciences Inc   (United States)

^c CALIFORNIA NANOSYSTEMS INSTITUTE   (United States)

^d UCLA MEDICAL CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Santa Monica UCLA Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITHELIAL CELL ADHESION MOLECULE;

ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CELL ISOLATION; CELL VIABILITY; CIRCULATING TUMOR CELL; EXTRACTION; HEMODILUTION; HUMAN; HUMAN CELL; LAB ON A CHIP; LEUKOCYTE; MICROFLUIDICS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN EXPRESSION;

ANTIBODIES, IMMOBILIZED; ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CELL ADHESION MOLECULES; CELL SEPARATION; CELL SHAPE; CELL SIZE; FEMALE; FLUORESCENT DYES; HUMANS; LEUKOCYTES; LUNG NEOPLASMS; MCF-7 CELLS; MICROFLUIDIC ANALYTICAL TECHNIQUES; NEOPLASTIC CELLS, CIRCULATING;

EID: 84889067161     PISSN: 14730197     EISSN: 14730189     Source Type: Journal    
DOI: 10.1039/c3lc50689d     Document Type: Article

References (78)

1. T. R. Ashworth A case of cancer in which cells similar to those in the tumours were seen in the blood after death Med. J. Aust. 1869 14 146 147
2. S. Paget The distribution of secondary growths in cancer of the breast Lancet 1889 133 3421 571 573
3. K. Pantel C. Alix-Panabieres Circulating tumor cells in cancer patients: challenges and perspectives. Trends Mol. Med. 2010 16 398 406
4. C. Alix-Panabieres K. Pantel Circulating tumor cells: liquid biopsy of cancer Clin. Chem. 2013 59 1 110 118
5. S. Nagrath et al., Isolation of rare circulating tumor cells in cancer patients by microchip technology Nature 2007 450 1235 1239
6. M. Cristofanilli et al., Circulating tumor cells in metastatic breast cancer: biologic staging beyond tumor burden Clin. Breast Cancer 2007 7 6 471 479
7. J. S. de Bono et al., Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer Clin. Cancer Res. 2008 14 6302 6309
8. G. T. Budd et al., Circulating tumor cells versus imaging - predicting overall survival in metastatic breast cancer Clin. Cancer Res. 2006 12 21 6403 6409
9. S. Riethdorf et al., Detection and HER2 expression of circulating tumor cells: prospective monitoring in breast cancer patients treated in the neoadjuvant GeparQuattro trial Clin. Cancer Res. 2010 16 9 2634 2645
10. M. Méndez A. Custodio M. Provencio New molecular targeted therapies for advanced non-small-cell lung cancer J. Thorac. Dis. 2011 3 30 56
11. P.L. Paris et al., Functional phenotyping and genotyping of circulating tumor cells from patients with castration resistant prostate cancer Cancer Lett. 2009 227 2 164 173
12. M. Pestrin et al., Correlation of HER2 status between primary tumors and corresponding circulating tumor cells in advanced breast cancer patients Breast Cancer Res. Treat. 2009 118 3 523 530
13. N. Xenidis et al., Cytokeratin-19 mRNA-positive circulating tumor cells after adjuvant chemotherapy in patients with early breast cancer J. Clin. Oncol. 2009 27 13 2177 2184
14. A. Marusyk V. Almendro K. Polyak Intra-tumour heterogeneity: a looking glass for cancer Nat. Rev. Cancer 2012 12 323 334
15. A. A. Powell et al., Single cell profiling of circulating tumor cells: transcriptional heterogeneity and diversity from breast cancer cell lines PLoS One 2012 7 5 e33788
16. M. Labelle R. O. Hynes The initial hours of metastasis: the importance of cooperative host-tumor cell interactions during hematogenous dissemination Cancer Discovery 2012 2 1091 1099
17. C. V. Pecot et al., A novel detection platform for detection of CK+ and CK- CTCs Cancer Discovery 2011 1 7 580 586
18. J. Kling Beyond counting tumor cells Nat. Biotechnol. 2012 30 7 578 580
19. K. Ameri et al., Circulating tumor cells demonstrate an altered response to hypoxia and an aggressive phenotype Br. J. Cancer 2010 102 561 569
20. P. Paterlini-Brechot N. L. Benali Circulating tumor cells (CTC) detection: clinical impact and future directions Cancer Lett. 2007 253 180 204
21. J. Chen J. Lib Y. Sun Microfluidic approaches for cancer cell detection, characterization, and separation Lab Chip 2012 12 1753 1767
22. Y. F. Sun et al., Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance J. Cancer Res. Clin. Oncol. 2011 137 1151 1173
23. M. Craig Miller G. V. Doyle L. W. M. M. Terstappen Review article: Significance of Circulating Tumor Cells Detected by the Cell Search System in Patients with Metastatic Breast, Colorectal and Prostate Cancer J. Oncol. 2010 617421
24. S. Riethdorf H. Fritsche V. Muller et al., Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the cell search system Clin. Cancer Res. 2007 13 3 920 928
25. A. A. H. Talasaz et al., Isolating highly enriched populations of circulating epithelial cells and other rare cells from blood using a magnetic sweeper device Proc. Natl. Acad. Sci. U. S. A. 2009 106 10 3970 3975
26. E. Andreopoulou et al., Comparison of assay methods for detection of circulating tumor cells in metastatic breast cancer: AdnaGenAdnaTestBreastCancer Select/Detect™ versus VeridexCellSearch™ system Int. J. Cancer 2012 130 1590 1597
27. J. H. Kang et al., A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells Lab Chip 2012 12 2175 2181
28. S. L. Stott et al., Isolation of circulating tumor cells using a microvortex-generating herringbone-chip Proc. Natl. Acad. Sci. U. S. A. 2010 107 43 18392 7
29. J. P. Gleghorn et al., Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody Lab Chip 2010 10 27 29
30. A. M. Shah et al., Biopolymer system for cell recovery from microfluidic cell capture devices Anal. Chem. 2012 84 3682 3688
31. J. A. Mayer et al., FISH-based determination of HER2 status in circulating tumor cells isolated with the microfluidic CEE platform Cancer Genet. 2011 204 589 595
32. D. Marrinucci et al., Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers Phys. Biol. 2012 9 016003
33. V. Gupta et al., ApoStream(tm), a new dielectrophoretic device for antibody independent isolation and recovery of viable cancer cells from blood Biomicrofluidics 2012 6 024133
34. P. Augustsson et al., Microfluidic, label-free enrichment of prostate cancer cells in blood based on acoustophoresis Anal. Chem. 2012 84 18 7954 7962
35. A. Williams M. Balic R. Datar R. Cote Size-based enrichment technologies for CTC detection and characterization Recent Results Cancer Res. 2012 195 87 95
36. G. Vona et al., Isolation by size of epithelial tumor cells: a new method for the immunomorphological and molecular characterization of circulating tumor cells Am. J. Pathol. 2000 156 1 57 63
37. H. K. Lin et al., Portable filter-based microdevice for detection and characterization of circulating tumor cells Clin. Cancer Res. 2010 16 20 5011 5018
38. S. Zheng et al., Membrane microfilter device for selective capture, electrolysis and genomic analysis of human circulating tumor cells J. Chromatogr., A 2007 1162 2 154 61
39. I. Desitter et al., A new device for rapid isolation by size and characterization of rare circulating tumor cells Anticancer Res. 2011 31 427 442
40. V. De Giorgi et al., Application of a filtration- and isolation-by-size technique for the detection of circulating tumor cells in cutaneous melanoma J. Invest. Dermatol. 2010 130 2440 2447
41. J. M. Hou et al., Circulating tumor cells as a window on metastasis biology in lung cancer Am. J. Pathol. 2011 178 3 989 996
42. J. den Toonder Circulating tumor cells: the Grand Challenge Lab Chip 2011 11 375 377
43. S. J. Tan et al., Microdevice for the isolation and enumeration of cancer cells from blood Biomed. Microdevices 2009 11 883 892
44. S. J. Tan et al., Versatile label free biochip for the detection of circulating tumor cells from peripheral blood in cancer patients Biosens. Bioelectron. 2010 26 1701 1705
45. E. Ozkumur et al., Inertial focusing for tumor antigen dependent and independent sorting of rare circulating tumor cells Sci. Transl. Med. 2013 5 179
46. H.W. Hou et al., Isolation and retrieval of circulating tumor cells using centrifugal forces Sci. Rep. 2013 3 1259 10.1038/srep01259
47. S. C. Hur A. J. Mach D. Di Carlo High-throughput size-based rare cell enrichment using microscale vortices Biomicrofluidics 2011 5 022206
48. A. J. Mach J. H. Kim A. Arshi S. C. Hur D. Di Carlo Automated cellular sample preparation using a Centrifuge-on-a-chip Lab Chip 2011 11 2827 2834
49. G. Segre A. Silberberg Radial particle displacements in Poiseuille flow of suspensions Nature 1961 189 209 210
50. D. Di Carlo Inertial microfluidics Lab Chip 2009 9 3038 3046
51. A. A. S. Bhagat et al., Inertial microfluidics for continuous particle filtration and extraction Microfluid. Nanofluid. 2008 7 217 226
52. D. Di Carlo J. F. Edd K. J. Humphry H. A. Stone M. Toner Particle segregation and dynamics in confined flows Phys. Rev. Lett. 2009 102 094503
53. S. C. Hur H. T. K. Tse D. Di Carlo Sheathless inertial cell ordering for extreme throughput flow cytometry Lab Chip 2010 10 274 280
54. A. J. Mach D. Di Carlo Continuous scalable blood filtration device using inertial microfluidics Biotechnol. Bioeng. 2010 107 20 302 311
55. S. C. Hur N. K. Henderson-MacLennan E. R. B. McCabe D. Di Carlo Deformability-based cell classification and enrichment using inertial microfluidics Lab Chip 2011 11 912 920
56. M. Masaeli et al., Continuous inertial focusing and separation of particles by shape Phys. Rev. X 2012 2 031017
57. H. Moffatt J. Fluid Mech. 1964 18 1 1 18
58. W. Cherdron F. Durst J. Whitelaw J. Fluid Mech. 1978 84 13
59. E. Sollier M. Cubizolles Y. Fouillet J.L. Achard Fast and continuous plasma extraction from whole human blood based on expanding cell-free layer devices Biomed. Microdevices 2010 12 3 485 97
60. J. Park H. Jung Anal. Chem. 2009 81 8280
61. M. Khabiry et al. Small 2009 51186
62. D. Di Carlo D. Irimia R. G. Tompkins M. Toner Proc. Natl. Acad. Sci. U. S. A. 2007 104 18892 18897
63. K. A. Hyun K. Kwon H. Han S. I. Kim H. I. Jung Microfluidic flow fractionation device for label-free isolation of circulating tumor cells (CTCs) from breast cancer patients Biosens. Bioelectron. 2013 40 1 206 12
64. D. C. Duffy J. C. McDonald O. J. A. Schueller G. M. Whitesides Rapid prototyping of microfluidic systems in poly(dimethylsiloxane) Anal. Chem. 1998 70 4974 4984
65. D. R. Gossett Hydrodynamic stretching of single cells for large population mechanical phenotyping Proc. Natl. Acad. Sci. U. S. A. 2012 109 20 7630 7635
66. E. Sollier et al., Rapid prototyping polymers for microfluidic devices and high pressure injections Lab Chip 2011 11 3752 3765
67. H. Amini et al., Engineering fluid flow using sequenced microstructures Nat. Commun. 2013 4 1826
68. R. Strauss et al., Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotype heterogeneity and plasticity PLoS One 2011 6 1 e16186
69. Y. Kim et al., Clinicopathological implications of EpCAM expression in adenocarcinoma of the lung Anticancer Res. 2009 29 5 1817 1822
70. D. C. Lazar et al., Cytometric comparisons between circulating tumor cells from prostate cancer patients and the prostate-tumor-derived LNCaP cell line Phys. Biol. 2012 9 016002
71. S. K. Lee et al., Nanowire substrate-based laser scanning cytometry for quantitation of circulating tumor cells Nano Lett. 2012 12 2697 2704
72. E. H. Cho et al., Characterization of circulating tumor cell aggregates identified in aptietns with epithelial tumors Phys. Biol. 2012 9 016001
73. M. Wendel et al., Fluid biopsy for circulating tumor cell identification in aptietns with early and late stage non small cell lung cancer: a glimpse into lung cancer biology Phys. Biol. 2012 9 016005
74. G.W. Schmid-Schonbein et al., Morphometry of human leukocytes Blood 1980 56 866 875
75. M. C. Miller G. V. Doyle L. W. M. M. Terstappen Significance of circulating tumor cells detected by the cell search system in patients with metastatic breast, colorectal and prostate cancer J. Oncol. 2010 2010 617421
76. K. Spanel-Borowski A. M. Ricken W. F. Patton Cytokeratin-positive and cytokeratin-negative cultured endothelial cells from bovine aorta and vena cava Differentiation 1994 57 3 225 234
77. J. Che et al., Microfluidic purification and concentration of malignant pleural effusions for improved molecular and cytomorphological diagnostics PLoS One 2013
78. J. Nieva et al., High-definition imaging of circulating tumor cells and associated cellular events in non-small cell lung cancer patients: a longitudinal analysis Phys. Biol. 2012 9 016004