Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205

Oncotarget

Volumn 7, Issue 52, 2016, Pages 87257-87270

  Zhang, Yi ^a   Xu, Xuefen ^a   Li, Wei ^a   Miao, Hanchi ^a   Huang, Shaoliang ^a   Zhou, Yuxin ^a   Sun, Yang ^a   Li, Zhiyu ^a   Guo, Qinglong ^a   Zhao, Li ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; ER stress; Extrinsic apoptosis; LZ 205; ROS

Indexed keywords

5 HYDROXY 8 METHOXY 7 [4 (PYRROLIDIN 1 YL)BUTOXY] 2 [4 (TRIFLUOROMETHYL)PHENYL] 4H CHROMEN 4 ONE; ANTINEOPLASTIC AGENT; FLAVONOID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG EFFECTS; LUNG TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM STRESS; FLAVONOIDS; HUMANS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; REACTIVE OXYGEN SPECIES; UNFOLDED PROTEIN RESPONSE;

EID: 85007494684     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.13535     Document Type: Article

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