Death receptors and mitochondria: Two prime triggers of neural apoptosis and differentiation

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 1, 2013, Pages 2160-2166

  Solá, Susana ^a,b   Morgado, Ana L ^a   Rodrigues, Cecília M P ^a,b  

^a UNIVERSITY OF LISBON   (Portugal)

^b RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

Death receptor; Mitochondrion; Neural differentiation; Stem cell

Indexed keywords

CASPASE; DEATH RECEPTOR; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE PEROXIDASE 1; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MAMMALIAN TARGET OF RAPAMYCIN; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NESTIN; PEROXIREDOXIN 5; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; SIRTUIN 1; STAT3 PROTEIN; TRANSCRIPTION FACTOR SOX2; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR; UNINDEXED DRUG;

APOPTOSIS; ASTROCYTE; CELL ACTIVATION; CELL ACTIVITY; CELL AGING; CELL DEATH; CELL FATE; CELL FUNCTION; CELL LOSS; CELL PROLIFERATION; CELL RENEWAL; CELL SPECIFICITY; CELL SURVIVAL; EMBRYONIC STEM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; INTRACELLULAR SIGNALING; MITOCHONDRIAL VOLUME; MITOCHONDRION; MOLECULAR MECHANICS; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; REGULATORY MECHANISM; REVIEW;

ANIMALS; APOPTOSIS; CASPASES; CELL DIFFERENTIATION; HUMANS; MITOCHONDRIA; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, DEATH DOMAIN; STEM CELL TRANSPLANTATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84868246871     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2012.09.021     Document Type: Review

References (70)

1. G.L. Ming, and H. Song Adult neurogenesis in the mammalian central nervous system Annu. Rev. Neurosci. 28 2005 223 250
2. A. Alvarez-Buylla, and J.M. Garcia-Verdugo Neurogenesis in adult subventricular zone J. Neurosci. 22 2002 629 634
3. F.H. Gage Mammalian neural stem cells Science 287 2000 1433 1438
4. G. Kempermann, and F.H. Gage Neurogenesis in the adult hippocampus Novartis Found. Symp. 231 2000 220 235
5. P. Fernando, and L.A. Megeney Is caspase-dependent apoptosis only cell differentiation taken to the extreme? FASEB J. 21 2007 8 17
6. P. Fernando, J.F. Kelly, K. Balazsi, R.S. Slack, and L.A. Megeney Caspase 3 activity is required for skeletal muscle differentiation Proc. Natl. Acad. Sci. U. S. A. 99 2002 11025 11030
7. S. Sola, M.M. Aranha, and C.M. Rodrigues Driving apoptosis-relevant proteins toward neural differentiation Mol. Neurobiol. 46 2012 316 331
8. M.M. Aranha, S. Sola, W.C. Low, C.J. Steer, and C.M. Rodrigues Caspases and p53 modulate FOXO3A/Id1 signaling during mouse neural stem cell differentiation J. Cell. Biochem. 107 2009 748 758
9. M.M. Aranha, D.M. Santos, J.M. Xavier, W.C. Low, C.J. Steer, S. Sola, and C.M. Rodrigues Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation BMC Genomics 11 2010 514
10. M.M. Aranha, D.M. Santos, S. Sola, C.J. Steer, and C.M. Rodrigues miR-34a regulates mouse neural stem cell differentiation PLoS One 6 2011 e21396
11. S. Solá, J.M. Xavier, D.M. Santos, M.M. Aranha, A.L. Morgado, K. Jepsen, and C.M. Rodrigues p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation PLoS One 6 2011 e18421
12. D.M. Santos, J.M. Xavier, A.L. Morgado, S. Solá, and C.M. Rodrigues Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation PLoS One 7 2012 e33468
13. H. Zheng, H. Ying, H. Yan, A.C. Kimmelman, D.J. Hiller, A.J. Chen, S.R. Perry, G. Tonon, G.C. Chu, Z. Ding, J.M. Stommel, K.L. Dunn, R. Wiedemeyer, M.J. You, C. Brennan, Y.A. Wang, K.L. Ligon, W.H. Wong, L. Chin, and R.A. DePinho p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation Nature 455 2008 1129 1133
14. S. Di Giovanni, C.D. Knights, M. Rao, A. Yakovlev, J. Beers, J. Catania, M.L. Avantaggiati, and A.I. Faden The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration EMBO J. 25 2006 4084 4096
15. L. Galluzzi, I. Vitale, J.M. Abrams, E.S. Alnemri, E.H. Baehrecke, M.V. Blagosklonny, T.M. Dawson, V.L. Dawson, W.S. El-Deiry, S. Fulda, E. Gottlieb, D.R. Green, M.O. Hengartner, O. Kepp, R.A. Knight, S. Kumar, S.A. Lipton, X. Lu, F. Madeo, W. Malorni, P. Mehlen, G. Nunez, M.E. Peter, M. Piacentini, D.C. Rubinsztein, Y. Shi, H.U. Simon, P. Vandenabeele, E. White, J. Yuan, B. Zhivotovsky, G. Melino, and G. Kroemer Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 Cell Death Differ. 19 2012 107 120
16. G.C. Parker, G. Acsadi, and C.A. Brenner Mitochondria: determinants of stem cell fate? Stem Cells Dev. 18 2009 803 806
17. W. Liao, J.X. Lin, and W.J. Leonard IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation Curr. Opin. Immunol. 23 2011 598 604
18. R.E. Ellis, J.Y. Yuan, and H.R. Horvitz Mechanisms and functions of cell death Annl. Rev. Cell Biol. 7 1991 663 698
19. G. Kroemer, L. Galluzzi, and C. Brenner Mitochondrial membrane permeabilization in cell death Physiol. Rev. 87 2007 99 163
20. N.A. Thornberry, and Y. Lazebnik Caspases: enemies within Science 281 1998 1312 1316
21. K.M. Debatin, and P.H. Krammer Death receptors in chemotherapy and cancer Oncogene 23 2004 2950 2966
22. C.H. Yi, and J. Yuan The Jekyll and Hyde functions of caspases Dev. Cell 16 2009 21 34
23. S.E. Chen, E. Gerken, Y. Zhang, M. Zhan, R.K. Mohan, A.S. Li, M.B. Reid, and Y.P. Li Role of TNF-{alpha} signaling in regeneration of cardiotoxin-injured muscle Am. J. Physiol. 289 2005 C1179 C1187
24. Y. Torrente, E. El Fahime, N.J. Caron, R. Del Bo, M. Belicchi, F. Pisati, J.P. Tremblay, and N. Bresolin Tumor necrosis factor-alpha (TNF-alpha) stimulates chemotactic response in mouse myogenic cells Cell Transplant. 12 2003 91 100
25. P. Chomarat, C. Dantin, L. Bennett, J. Banchereau, and A.K. Palucka TNF skews monocyte differentiation from macrophages to dendritic cells J. Immunol. 171 2003 2262 2269
26. E. Rimondi, P. Secchiero, A. Quaroni, C. Zerbinati, S. Capitani, and G. Zauli Involvement of TRAIL/TRAIL-receptors in human intestinal cell differentiation J. Cell. Physiol. 206 2006 647 654
27. L. Bernardino, F. Agasse, B. Silva, R. Ferreira, S. Grade, and J.O. Malva Tumor necrosis factor-alpha modulates survival, proliferation, and neuronal differentiation in neonatal subventricular zone cell cultures Stem Cells 26 2008 2361 2371
28. Y. Zhang, J. Liu, S. Yao, F. Li, L. Xin, M. Lai, V. Bracchi-Ricard, H. Xu, W. Yen, W. Meng, S. Liu, L. Yang, S. Karmally, H. Zhu, J. Gordon, K. Khalili, S. Srinivasan, J.R. Bethea, X. Mo, and W. Hu Nuclear factor kappa B signaling initiates early differentiation of neural stem cells Stem Cells 30 2012 510 524
29. N.S. Corsini, I. Sancho-Martinez, S. Laudenklos, D. Glagow, S. Kumar, E. Letellier, P. Koch, M. Teodorczyk, S. Kleber, S. Klussmann, B. Wiestler, O. Brustle, W. Mueller, C. Gieffers, O. Hill, M. Thiemann, M. Seedorf, N. Gretz, R. Sprengel, T. Celikel, and A. Martin-Villalba The death receptor CD95 activates adult neural stem cells for working memory formation and brain repair Cell Stem Cell 5 2009 178 190
30. Y. Niu, Y. Li, J. Zang, H. Huang, J. Deng, Z. Cui, and D. Yu Death receptor 5 and neuroproliferation Cell. Mol. Neurobiol. 32 2012 255 265
31. H. Peng, L. Sun, B. Jia, X. Lan, B. Zhu, Y. Wu, and J. Zheng HIV-1-infected and immune-activated macrophages induce astrocytic differentiation of human cortical neural progenitor cells via the STAT3 pathway PLoS One 6 2011 e19439
32. V. Egea, L. von Baumgarten, C. Schichor, B. Berninger, T. Popp, P. Neth, R. Goldbrunner, Y. Kienast, F. Winkler, M. Jochum, and C. Ries TNF-alpha respecifies human mesenchymal stem cells to a neural fate and promotes migration toward experimental glioma Cell Death Differ. 18 2011 853 863
33. M.A. Ajmone-Cat, E. Cacci, Y. Ragazzoni, L. Minghetti, and S. Biagioni Pro-gliogenic effect of IL-1alpha in the differentiation of embryonic neural precursor cells in vitro J. Neurochem. 113 2010 1060 1072
34. S.J. Crampton, L.M. Collins, A. Toulouse, Y.M. Nolan, and G.W. O'Keeffe Exposure of foetal neural progenitor cells to IL-1beta impairs their proliferation and alters their differentiation - a role for maternal inflammation? J. Neurochem. 120 2012 964 973
35. H.M. McBride, M. Neuspiel, and S. Wasiak Mitochondria: more than just a powerhouse Curr. Biol. 16 2006 R551 R560
36. I.J. Holt, J. He, C.C. Mao, J.D. Boyd-Kirkup, P. Martinsson, H. Sembongi, A. Reyes, and J.N. Spelbrink Mammalian mitochondrial nucleoids: organizing an independently minded genome Mitochondrion 7 2007 311 321
37. S. Mandal, A.G. Lindgren, A.S. Srivastava, A.T. Clark, and U. Banerjee Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells Stem Cells 29 2011 486 495
38. S.A. Detmer, and D.C. Chan Functions and dysfunctions of mitochondrial dynamics Nat. Rev. Mol. Cell Biol. 8 2007 870 879
39. P. Nagley, G.C. Higgins, J.D. Atkin, and P.M. Beart Multifaceted deaths orchestrated by mitochondria in neurones Biochim. Biophys. Acta 1802 2010 167 185
40. W. Wang, P. Osenbroch, R. Skinnes, Y. Esbensen, M. Bjoras, and L. Eide Mitochondrial DNA integrity is essential for mitochondrial maturation during differentiation of neural stem cells Stem Cells 28 2010 2195 2204
41. R.W. Siggins, P. Zhang, D. Welsh, N.J. Lecapitaine, and S. Nelson Stem cells, phenotypic inversion, and differentiation Int. J. Clin. Exp. Med. 1 2008 2 21
42. V. Voccoli, and L. Colombaioni Mitochondrial remodeling in differentiating neuroblasts Brain Res. 1252 2009 15 29
43. A. Cheng, Y. Hou, and M.P. Mattson Mitochondria and neuroplasticity ASN Neuro 2 2010 e00045
44. H. Kondoh, M.E. Lleonart, Y. Nakashima, M. Yokode, M. Tanaka, D. Bernard, J. Gil, and D. Beach A high glycolytic flux supports the proliferative potential of murine embryonic stem cells Antioxid. Redox Signal. 9 2007 293 299
45. J.Y. Park, P.Y. Wang, T. Matsumoto, H.J. Sung, W. Ma, J.W. Choi, S.A. Anderson, S.C. Leary, R.S. Balaban, J.G. Kang, and P.M. Hwang p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content Circ. Res. 105 2009 705 712
46. M.A. Lebedeva, J.S. Eaton, and G.S. Shadel Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis Biochim. Biophys. Acta 1787 2009 328 334
47. J. Zhang, W. Yan, and X. Chen p53 is required for nerve growth factor-mediated differentiation of PC12 cells via regulation of TrkA levels Cell Death Differ. 13 2006 2118 2128
48. M. Uittenbogaard, K.K. Baxter, and A. Chiaramello The neurogenic basic helix-loop-helix transcription factor NeuroD6 confers tolerance to oxidative stress by triggering an antioxidant response and sustaining the mitochondrial biomass ASN Neuro. 2 2010 e00034
49. W. Wang, Y. Esbensen, D. Kunke, R. Suganthan, L. Rachek, M. Bjoras, and L. Eide Mitochondrial DNA damage level determines neural stem cell differentiation fate J. Neurosci. 31 2011 9746 9751
50. A.Y. Abramov, T.K. Smulders-Srinivasan, D.M. Kirby, R. Acin-Perez, J.A. Enriquez, R.N. Lightowlers, M.R. Duchen, and D.M. Turnbull Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations Brain 133 2010 797 807
51. A.J. Trevelyan, D.M. Kirby, T.K. Smulders-Srinivasan, M. Nooteboom, R. Acin-Perez, J.A. Enriquez, M.A. Whittington, R.N. Lightowlers, and D.M. Turnbull Mitochondrial DNA mutations affect calcium handling in differentiated neurons Brain 133 2010 787 796
52. C. Garrido, L. Galluzzi, M. Brunet, P.E. Puig, C. Didelot, and G. Kroemer Mechanisms of cytochrome c release from mitochondria Cell Death Differ. 13 2006 1423 1433
53. I. Liste, E. Garcia-Garcia, C. Bueno, and A. Martinez-Serrano Bcl-XL modulates the differentiation of immortalized human neural stem cells Cell Death Differ. 14 2007 1880 1892
54. C.M. Sauvageot, and C.D. Stiles Molecular mechanisms controlling cortical gliogenesis Curr. Opin. Neurobiol. 12 2002 244 249
55. M. Krajewska, J.K. Mai, J.M. Zapata, K.W. Ashwell, S.L. Schendel, J.C. Reed, and S. Krajewski Dynamics of expression of apoptosis-regulatory proteins Bid, Bcl-2, Bcl-X, Bax and Bak during development of murine nervous system Cell Death Differ. 9 2002 145 157
56. E. Bunk, H.-G. König, T. Bernas, T. Engel, D. Henshall, B. Kirby, and J. Prehn BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus Cell Death Dis. 1 2010 1 9
57. M.Y. Chang, W. Sun, W. Ochiai, K. Nakashima, S.Y. Kim, C.H. Park, J.S. Kang, J.W. Shim, A.Y. Jo, C.S. Kang, Y.S. Lee, J.S. Kim, and S.H. Lee Bcl-XL/Bax proteins direct the fate of embryonic cortical precursor cells Mol. Cell. Biol. 27 2007 4293 4305
58. M. Uittenbogaard, and A. Chiaramello The basic helix-loop-helix transcription factor Nex-1/Math-2 promotes neuronal survival of PC12 cells by modulating the dynamic expression of anti-apoptotic and cell cycle regulators J. Neurochem. 92 2005 585 596
59. R. Behjati, K. Kawai, Y. Inadome, J. Kano, H. Akaza, and M. Noguchi APAF-1 is related to an undifferentiated state in the testicular germ cell tumor pathway Cancer Sci. 102 2011 267 274
60. E. Ferraro, M.G. Pesaresi, D. De Zio, M.T. Cencioni, A. Gortat, M. Cozzolino, L. Berghella, A.M. Salvatore, B. Oettinghaus, L. Scorrano, E. Perez-Paya, and F. Cecconi Apaf1 plays a pro-survival role by regulating centrosome morphology and function J. Cell Sci. 124 2011 3450 3463
61. K.M. Wright, M.W. Linhoff, P.R. Potts, and M. Deshmukh Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis J. Cell. Biol. 167 2004 303 313
62. M. Cozzolino, E. Ferraro, A. Ferri, D. Rigamonti, F. Quondamatteo, H. Ding, Z.S. Xu, F. Ferrari, D.F. Angelini, G. Rotilio, E. Cattaneo, M.T. Carri, and F. Cecconi Apoptosome inactivation rescues proneural and neural cells from neurodegeneration Cell Death Differ. 11 2004 1179 1191
63. Y.M. Cho, S. Kwon, Y.K. Pak, H.W. Seol, Y.M. Choi, J. Park do, K.S. Park, and H.K. Lee Dynamic changes in mitochondrial biogenesis and antioxidant enzymes during the spontaneous differentiation of human embryonic stem cells Biochem. Biophys. Res. Commun. 348 2006 1472 1478
64. L. Armstrong, K. Tilgner, G. Saretzki, S.P. Atkinson, M. Stojkovic, R. Moreno, S. Przyborski, and M. Lako Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells Stem Cells 28 2010 661 673
65. A. Prigione, B. Fauler, R. Lurz, H. Lehrach, and J. Adjaye The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells Stem Cells 28 2010 721 733
66. T. Lonergan, C. Brenner, and B. Bavister Differentiation-related changes in mitochondrial properties as indicators of stem cell competence J. Cell. Physiol. 208 2006 149 153
67. C.T. Chen, Y.R. Shih, T.K. Kuo, O.K. Lee, and Y.H. Wei Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells Stem Cells 26 2008 960 968
68. M. Tsatmali, E.C. Walcott, and K.L. Crossin Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors Brain Res. 1040 2005 137 150
69. M.J. Birket, A.L. Orr, A.A. Gerencser, D.T. Madden, C. Vitelli, A. Swistowski, M.D. Brand, and X. Zeng A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells J. Cell Sci. 124 2011 348 358
70. J.E. Le Belle, N.M. Orozco, A.A. Paucar, J.P. Saxe, J. Mottahedeh, A.D. Pyle, H. Wu, and H.I. Kornblum Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/Akt-dependant manner Cell Stem Cell 8 2011 59 71