Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1α and glycolysis, by inhibiting PI3K/Akt signaling pathway

Molecular Carcinogenesis

Volumn 53, Issue S1, 2014, Pages

  Wang, Hu ^a   Zhao, Li ^a   Zhu, Li Tao ^a   Wang, Yu ^a   Pan, Di ^a   Yao, Jing ^a   You, Qi Dong ^a   Guo, Qing Long ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

HIF 1 ; Hypoxia; Reversal effect; Wogonin

Indexed keywords

HIF-1Α; HYPOXIA; REVERSAL EFFECT; WOGONIN;

ANIMALS; ANOXIA; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; COLONIC NEOPLASMS; DOWN-REGULATION; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUGS, CHINESE HERBAL; FLAVANONES; FLOW CYTOMETRY; GLUCOSE; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOENZYME TECHNIQUES; LACTATES; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84894484422     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22052     Document Type: Article

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