Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1

Archives of Toxicology

Volumn 76, Issue 5-6, 2002, Pages 351-359

  Chen, Yen Chou ^a   Shen, Shing Chuan ^b,c   Lee, Woan Rouh ^a   Lin, Hui Yi ^a   Ko, Ching Huai ^a   Shih, Chun Ming ^b   Yang, Ling Ling ^a  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Apoptosis; Caspase 3; Fisetin; Protein p21; Protein p53; Wogonin

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CASPASE 3 INHIBITOR; DNA FRAGMENT; FISETIN; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 1BETA CONVERTING ENZYME INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN; PROTEIN D4 GDI; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG; WOGONIN; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASPASE; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; FLAVANONE DERIVATIVE; FLAVONOID;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL LINE; CELL SWELLING; CONCENTRATION RESPONSE; DIPLOIDY; DRUG CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INDUCTION; ENZYME SUBSTRATE; FLOW CYTOMETRY; GIEMSA STAIN; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; STARVATION; BIOSYNTHESIS; CELL CULTURE; GENETICS; HUMAN; METABOLISM; PATHOLOGY; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CASPASE 1; CASPASES; CYCLINS; ENZYME ACTIVATION; FLAVONES; FLOW CYTOMETRY; HUMAN; PROTEIN P53; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED; CASPASE 3; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FLAVANONES; FLAVONOIDS; HUMANS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036016874     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-002-0346-6     Document Type: Article

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