Succinate dehydrogenase inhibition with malonate during reperfusion reduces infarct size by preventing mitochondrial permeability transition

Cardiovascular Research

Volumn 109, Issue 3, 2016, Pages 374-384

  Valls Lacalle, Laura ^a   Barba, Ignasi ^a   Miró Casas, Elisabet ^a   Alburquerque Béjar, Juan José ^a   Ruiz Meana, Marisol ^a   Fuertes Agudo, Marina ^a   Rodríguez Sinovas, Antonio ^a   García Dorado, David ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

Malonate; Reperfusion injury; ROS; Succinate dehydrogenase

Indexed keywords

ACETIC ACID; ADENOSINE PHOSPHATE; ALANINE; ASPARTIC ACID; BETAINE; CALCEIN; CARNITINE; CHOLINE; CREATINE; CREATINE PHOSPHATE; DISODIUM MALONATE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; GLYCOGEN SYNTHASE KINASE 3BETA; HEART MUSCLE EXTRACT; LACTATE DEHYDROGENASE; LACTIC ACID; MALONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PROPIONIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); STAT3 PROTEIN; SUCCINATE DEHYDROGENASE; SUCCINIC ACID; TAURINE; THREONINE; UNCLASSIFIED DRUG; CARDIOTONIC AGENT; CARRIER PROTEIN; MALONIC ACID DERIVATIVE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME RELEASE; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE METABOLISM; HEART PROTECTION; HEART RATE; HEART VENTRICLE ENDDIASTOLIC PRESSURE; ISOLATED HEART; MALE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; REPERFUSION INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DRUG EFFECTS; HEART MITOCHONDRION; METABOLISM; MYOCARDIAL REPERFUSION INJURY;

ANIMALS; CARDIOTONIC AGENTS; L-LACTATE DEHYDROGENASE; MALE; MALONATES; MICE, INBRED C57BL; MITOCHONDRIA, HEART; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MYOCARDIAL REPERFUSION INJURY; SUCCINATE DEHYDROGENASE;

EID: 84959923890     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvv279     Document Type: Article

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