Characterisation of an aerosol exposure system to evaluate the genotoxicity of whole mainstream cigarette smoke using the in vitro γH2AX assay by high content screening

BMC Pharmacology and Toxicology

Volumn 15, Issue 1, 2014, Pages

  Garcia Canton, Carolina ^a,b   Errington, Graham ^a   Anadon, Arturo ^b   Meredith, Clive ^a  

^a BRITISH AMERICAN TOBACCO   (United Kingdom)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Cigarette smoke; DNA damage; GammaH2AX; Genotoxicity; High content screening; In vitro

Indexed keywords

CIGARETTE SMOKE; HISTONE H2AX; AEROSOL; H2AFX PROTEIN, HUMAN; HISTONE; SMOKE;

AEROSOL; ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; ENVIRONMENTAL EXPOSURE; GAMMAHISTONE H2AX ASSAY; GENOTOXICITY ASSAY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; MEASUREMENT REPEATABILITY; REPRODUCIBILITY; SCORING SYSTEM; TOXICITY TESTING; CELL LINE; METABOLISM; MUTAGEN TESTING; SMOKE; TOBACCO;

AEROSOLS; CELL LINE; HISTONES; HUMANS; IN VITRO TECHNIQUES; MUTAGENICITY TESTS; SMOKE; TOBACCO;

EID: 84926088290     PISSN: None     EISSN: 20506511     Source Type: Journal    
DOI: 10.1186/2050-6511-15-41     Document Type: Article

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