-
1
-
-
84960949820
-
Cancer: a biological approach. III. Viruses associated with neoplastic conditions. IV. Practical applications
-
Burnet M. Cancer: a biological approach. III. Viruses associated with neoplastic conditions. IV. Practical applications. Br Med J (1957) 1(5023):841-7. doi:10.1136/bmj.1.5023.841
-
(1957)
Br Med J
, vol.1
, Issue.5023
, pp. 841-847
-
-
Burnet, M.1
-
2
-
-
84864214537
-
Ectopic expression of TIM-3 in lung cancers: a potential independent prognostic factor for patients with NSCLC
-
Zhuang X, Zhang X, Xia X, Zhang C, Liang X, Gao L, et al. Ectopic expression of TIM-3 in lung cancers: a potential independent prognostic factor for patients with NSCLC. Am J Clin Pathol (2012) 137(6):978-85. doi:10.1309/AJCP9Q6OVLVSHTMY
-
(2012)
Am J Clin Pathol
, vol.137
, Issue.6
, pp. 978-985
-
-
Zhuang, X.1
Zhang, X.2
Xia, X.3
Zhang, C.4
Liang, X.5
Gao, L.6
-
3
-
-
4344671644
-
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance
-
Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Liénard D, Lejeune F, et al. Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res (2004) 64(8):2865-73. doi:10.1158/0008-5472.CAN-03-3066
-
(2004)
Cancer Res
, vol.64
, Issue.8
, pp. 2865-2873
-
-
Zippelius, A.1
Batard, P.2
Rubio-Godoy, V.3
Bioley, G.4
Liénard, D.5
Lejeune, F.6
-
4
-
-
0032416085
-
Viral immune evasion due to persistence of activated T cells without effector function
-
Zajac AJ, Blattman JN, Murali-Krishna K, Sourdive DJ, Suresh M, Altman JD, et al. Viral immune evasion due to persistence of activated T cells without effector function. J Exp Med (1998) 188(12):2205-13. doi:10.1084/jem.188.12.2205
-
(1998)
J Exp Med
, vol.188
, Issue.12
, pp. 2205-2213
-
-
Zajac, A.J.1
Blattman, J.N.2
Murali-Krishna, K.3
Sourdive, D.J.4
Suresh, M.5
Altman, J.D.6
-
5
-
-
35349014587
-
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
-
Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, et al. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity (2007) 27(4):670-84. doi:10.1016/j.immuni.2007.09.006
-
(2007)
Immunity
, vol.27
, Issue.4
, pp. 670-684
-
-
Wherry, E.J.1
Ha, S.J.2
Kaech, S.M.3
Haining, W.N.4
Sarkar, S.5
Kalia, V.6
-
6
-
-
84937837169
-
Molecular and cellular insights into T cell exhaustion
-
Wherry EJ, Kurachi M. Molecular and cellular insights into T cell exhaustion. Nat Rev Immunol (2015) 15(8):486-99. doi:10.1038/nri3862
-
(2015)
Nat Rev Immunol
, vol.15
, Issue.8
, pp. 486-499
-
-
Wherry, E.J.1
Kurachi, M.2
-
7
-
-
0033024863
-
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993
-
Atkins MB, Lotze MT, Dutcher JP, Fisher RI, Weiss G, Margolin K, et al. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993. J Clin Oncol (1999) 17(7):2105-16.
-
(1999)
J Clin Oncol
, vol.17
, Issue.7
, pp. 2105-2116
-
-
Atkins, M.B.1
Lotze, M.T.2
Dutcher, J.P.3
Fisher, R.I.4
Weiss, G.5
Margolin, K.6
-
8
-
-
0033848628
-
High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update
-
Atkins MB, Kunkel L, Sznol M, Rosenberg SA. High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival update. Cancer J Sci Am (2000) 6(Suppl 1):S11-4.
-
(2000)
Cancer J Sci Am
, vol.6
, pp. S11-S14
-
-
Atkins, M.B.1
Kunkel, L.2
Sznol, M.3
Rosenberg, S.A.4
-
9
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, Postow MA, Rizvi NA, Lesokhin AM, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med (2013) 369(2):122-33. doi:10.1056/NEJMoa1302369
-
(2013)
N Engl J Med
, vol.369
, Issue.2
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
Postow, M.A.4
Rizvi, N.A.5
Lesokhin, A.M.6
-
10
-
-
84929481482
-
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
-
Postow MA, Chesney J, Pavlick AC, Robert C, Grossmann K, McDermott D, et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. N Engl J Med (2015) 372(21):2006-17. doi:10.1056/NEJMoa1414428
-
(2015)
N Engl J Med
, vol.372
, Issue.21
, pp. 2006-2017
-
-
Postow, M.A.1
Chesney, J.2
Pavlick, A.C.3
Robert, C.4
Grossmann, K.5
McDermott, D.6
-
11
-
-
0018118221
-
Long-term results in combined-modality treatment of small cell carcinoma of the lung
-
Einhorn LH, Bond WH, Hornback N, Joe BT. Long-term results in combined-modality treatment of small cell carcinoma of the lung. Semin Oncol (1978) 5(3):309-13.
-
(1978)
Semin Oncol
, vol.5
, Issue.3
, pp. 309-313
-
-
Einhorn, L.H.1
Bond, W.H.2
Hornback, N.3
Joe, B.T.4
-
12
-
-
0026653868
-
Interleukin-2 and interferon-alpha in the treatment of patients with advanced non-small-cell lung cancer
-
Jansen RL, Slingerland R, Goey SH, Franks CR, Bolhuis RL, Stoter G. Interleukin-2 and interferon-alpha in the treatment of patients with advanced non-small-cell lung cancer. J Immunother (1992) 12(1):70-3. doi:10.1097/00002371-199207000-00009
-
(1992)
J Immunother
, vol.12
, Issue.1
, pp. 70-73
-
-
Jansen, R.L.1
Slingerland, R.2
Goey, S.H.3
Franks, C.R.4
Bolhuis, R.L.5
Stoter, G.6
-
13
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med (2012) 366(26):2443-54. doi:10.1056/NEJMoa1200690
-
(2012)
N Engl J Med
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
14
-
-
84936749833
-
Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer
-
Gettinger SN, Horn L, Gandhi L, Spigel DR, Antonia SJ, Rizvi NA, et al. Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer. J Clin Oncol (2015) 33(18):2004-12. doi:10.1200/JCO.2014.58.3708
-
(2015)
J Clin Oncol
, vol.33
, Issue.18
, pp. 2004-2012
-
-
Gettinger, S.N.1
Horn, L.2
Gandhi, L.3
Spigel, D.R.4
Antonia, S.J.5
Rizvi, N.A.6
-
15
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P, Crinò L, Eberhardt WEE, Poddubskaya E, et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Medicine (2015) 373(2):123-35. doi:10.1056/NEJMoa1504627
-
(2015)
N Engl J Medicine
, vol.373
, Issue.2
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crinò, L.4
Eberhardt, W.E.E.5
Poddubskaya, E.6
-
16
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei H, Paz-Ares L, Horn L, Spigel DR, Steins M, Ready NE, et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med (2015) 373(17):1627-39. doi:10.1056/NEJMoa1507643
-
(2015)
N Engl J Med
, vol.373
, Issue.17
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
Spigel, D.R.4
Steins, M.5
Ready, N.E.6
-
17
-
-
84950117835
-
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
-
10027
-
Herbst RS, Baas P, Kim DW, Felip E, Pérez-Gracia JL, Han JY, et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet (2016) 387(10027):1540-50. doi:10.1016/S0140-6736(15)01281-7
-
(2016)
Lancet
, vol.387
, pp. 1540-1550
-
-
Herbst, R.S.1
Baas, P.2
Kim, D.W.3
Felip, E.4
Pérez-Gracia, J.L.5
Han, J.Y.6
-
18
-
-
0032736029
-
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
-
Dong H, Zhu G, Tamada K, Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med (1999) 5(12):1365-9. doi:10.1038/70932
-
(1999)
Nat Med
, vol.5
, Issue.12
, pp. 1365-1369
-
-
Dong, H.1
Zhu, G.2
Tamada, K.3
Chen, L.4
-
19
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat Immunol (2001) 2(3):261-8. doi:10.1038/85330
-
(2001)
Nat Immunol
, vol.2
, Issue.3
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
-
20
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med (2000) 192(7):1027-34. doi:10.1084/jem.192.7.1027
-
(2000)
J Exp Med
, vol.192
, Issue.7
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
-
21
-
-
84962038946
-
Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial
-
10030
-
Fehrenbacher L, Spira A, Ballinger M, Kowanetz M, Vansteenkiste J, Mazieres J, et al. Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial. Lancet (2016) 387(10030):1837-46. doi:10.1016/S0140-6736(16)00587-0
-
(2016)
Lancet
, vol.387
, pp. 1837-1846
-
-
Fehrenbacher, L.1
Spira, A.2
Ballinger, M.3
Kowanetz, M.4
Vansteenkiste, J.5
Mazieres, J.6
-
22
-
-
85009840975
-
16LBA Phase II, single-arm trial (BIRCH) of atezolizumab as first-line or subsequent therapy for locally advanced or metastatic PD-L1-selected non-small cell lung cancer (NSCLC)
-
Besse B, Johnson M, Janne PA, Garassino M, Eberhardt WEE, Peter S, et al. 16LBA Phase II, single-arm trial (BIRCH) of atezolizumab as first-line or subsequent therapy for locally advanced or metastatic PD-L1-selected non-small cell lung cancer (NSCLC). Eur J Cancer (2015) 51:S717-8. doi:10.1016/S0959-8049(16)31938-4
-
(2015)
Eur J Cancer
, vol.51
, pp. S717-S718
-
-
Besse, B.1
Johnson, M.2
Janne, P.A.3
Garassino, M.4
Eberhardt, W.E.E.5
Peter, S.6
-
23
-
-
84944734156
-
Safety and clinical activity of MEDI4736, an anti-programmed cell death-ligand 1 (PD-L1) antibody, in patients with non-small cell lung cancer (NSCLC)
-
Rizvi NA. Safety and clinical activity of MEDI4736, an anti-programmed cell death-ligand 1 (PD-L1) antibody, in patients with non-small cell lung cancer (NSCLC). J Clin Oncol (2015) 33(S1):8032.
-
(2015)
J Clin Oncol
, vol.33
, pp. 8032
-
-
Rizvi, N.A.1
-
24
-
-
85006393710
-
Safety and clinical activity of durvalumab (MEDI4736), an anti-PD-L1 antibody, in treatment-naïve patients with advanced non-small-cell lung cancer
-
Antonia S. Safety and clinical activity of durvalumab (MEDI4736), an anti-PD-L1 antibody, in treatment-naïve patients with advanced non-small-cell lung cancer. J Clin Oncol (2016) 34(15_suppl):9029.
-
(2016)
J Clin Oncol
, vol.34
, Issue.15
, pp. 9029
-
-
Antonia, S.1
-
25
-
-
84944751040
-
Avelumab (MSB0010718C), an anti-PD-L1 antibody, in advanced NSCLC patients: a phase 1b, open-label expansion trial in patients progressing after platinum-based chemotherapy
-
Gulley JL, Spigel D, Kelly K, Chandler JC, Rajan A, Hassan R, et al. Avelumab (MSB0010718C), an anti-PD-L1 antibody, in advanced NSCLC patients: a phase 1b, open-label expansion trial in patients progressing after platinum-based chemotherapy. J Clin Oncol (2015) 33(15_suppl):8034.
-
(2015)
J Clin Oncol
, vol.33
, Issue.15
, pp. 8034
-
-
Gulley, J.L.1
Spigel, D.2
Kelly, K.3
Chandler, J.C.4
Rajan, A.5
Hassan, R.6
-
26
-
-
49049089802
-
Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
-
Scagliotti GV, Parikh P, von Pawel J, Biesma B, Vansteenkiste J, Manegold C, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol (2008) 26(21):3543-51. doi:10.1200/JCO.2007.15.0375
-
(2008)
J Clin Oncol
, vol.26
, Issue.21
, pp. 3543-3551
-
-
Scagliotti, G.V.1
Parikh, P.2
von Pawel, J.3
Biesma, B.4
Vansteenkiste, J.5
Manegold, C.6
-
27
-
-
84859128199
-
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
-
Taube JM, Anders RA, Young GD, Xu H, Sharma R, McMiller TL, et al. Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Sci Transl Med (2012) 4(127):127ra137. doi:10.1126/scitranslmed.3003689
-
(2012)
Sci Transl Med
, vol.4
, Issue.127
-
-
Taube, J.M.1
Anders, R.A.2
Young, G.D.3
Xu, H.4
Sharma, R.5
McMiller, T.L.6
-
28
-
-
84962129035
-
Progression of lung cancer is associated with increased dysfunction of T cells defined by coexpression of multiple inhibitory receptors
-
Thommen DS, Schreiner J, Müller P, Herzig P, Roller A, Belousov A, et al. Progression of lung cancer is associated with increased dysfunction of T cells defined by coexpression of multiple inhibitory receptors. Cancer Immunol Res (2015) 3(12):1344-55. doi:10.1158/2326-6066.CIR-15-0097
-
(2015)
Cancer Immunol Res
, vol.3
, Issue.12
, pp. 1344-1355
-
-
Thommen, D.S.1
Schreiner, J.2
Müller, P.3
Herzig, P.4
Roller, A.5
Belousov, A.6
-
29
-
-
84928761118
-
Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
Rizvi NA, Hellmann MD, Snyder A, Kvistborg P, Makarov V, Havel JJ, et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science (2015) 348(6230):124-8. doi:10.1126/science.aaa1348
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
Kvistborg, P.4
Makarov, V.5
Havel, J.J.6
-
30
-
-
84966309581
-
Cancer immunology. The "cancer immunogram"
-
Blank CU, Haanen JB, Ribas A, Schumacher TN. Cancer immunology. The "cancer immunogram". Science (2016) 352(6286):658-60. doi:10.1126/science.aaf2834
-
(2016)
Science
, vol.352
, Issue.6286
, pp. 658-660
-
-
Blank, C.U.1
Haanen, J.B.2
Ribas, A.3
Schumacher, T.N.4
-
31
-
-
78449258549
-
Development of ipilimumab: contribution to a new paradigm for cancer immunotherapy
-
Hoos A, Ibrahim R, Korman A, Abdallah K, Berman D, Shahabi V, et al. Development of ipilimumab: contribution to a new paradigm for cancer immunotherapy. Semin Oncol (2010) 37(5):533-46. doi:10.1053/j.seminoncol.2010.09.015
-
(2010)
Semin Oncol
, vol.37
, Issue.5
, pp. 533-546
-
-
Hoos, A.1
Ibrahim, R.2
Korman, A.3
Abdallah, K.4
Berman, D.5
Shahabi, V.6
-
32
-
-
84863113633
-
Immunotherapies for non-small-cell lung cancer and mesothelioma
-
Thomas A, Hassan R. Immunotherapies for non-small-cell lung cancer and mesothelioma. Lancet Oncol (2012) 13(7):e301-10. doi:10.1016/S1470-2045(12)70126-2
-
(2012)
Lancet Oncol
, vol.13
, Issue.7
, pp. e301-e310
-
-
Thomas, A.1
Hassan, R.2
-
33
-
-
84863911486
-
Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study
-
Lynch TJ, Bondarenko I, Luft A, Serwatowski P, Barlesi F, Chacko R, et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. J Clin Oncol (2012) 30(17):2046-54. doi:10.1200/JCO.2011.38.4032
-
(2012)
J Clin Oncol
, vol.30
, Issue.17
, pp. 2046-2054
-
-
Lynch, T.J.1
Bondarenko, I.2
Luft, A.3
Serwatowski, P.4
Barlesi, F.5
Chacko, R.6
-
34
-
-
84881086323
-
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
-
Timp W, Feinberg AP. Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat Rev Cancer (2013) 13(7):497-510. doi:10.1038/nrc3486
-
(2013)
Nat Rev Cancer
, vol.13
, Issue.7
, pp. 497-510
-
-
Timp, W.1
Feinberg, A.P.2
-
35
-
-
77954122580
-
Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors
-
Cowan LA, Talwar S, Yang AS. Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors. Epigenomics (2010) 2(1):71-86. doi:10.2217/epi.09.44
-
(2010)
Epigenomics
, vol.2
, Issue.1
, pp. 71-86
-
-
Cowan, L.A.1
Talwar, S.2
Yang, A.S.3
-
36
-
-
84946222432
-
Aberrant epigenetic regulation: a central contributor to lung carcinogenesis and a new therapeutic target
-
Juergens RA, Rudin CM. Aberrant epigenetic regulation: a central contributor to lung carcinogenesis and a new therapeutic target. Am Soc Clin Oncol Educ Book (2013) 2013:295-300. doi:10.1200/EdBook_AM.2013.33.e295
-
(2013)
Am Soc Clin Oncol Educ Book
, vol.2013
, pp. 295-300
-
-
Juergens, R.A.1
Rudin, C.M.2
-
37
-
-
84655163371
-
Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer
-
Juergens RA, Wrangle J, Vendetti FP, Murphy SC, Zhao M, Coleman B, et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discov (2011) 1(7):598-607. doi:10.1158/2159-8290.CD-11-0214
-
(2011)
Cancer Discov
, vol.1
, Issue.7
, pp. 598-607
-
-
Juergens, R.A.1
Wrangle, J.2
Vendetti, F.P.3
Murphy, S.C.4
Zhao, M.5
Coleman, B.6
-
38
-
-
84940403834
-
DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts
-
Roulois D, Loo Yau H, Singhania R, Wang Y, Danesh A, Shen SY, et al. DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts. Cell (2015) 162(5):961-73. doi:10.1016/j.cell.2015.07.056
-
(2015)
Cell
, vol.162
, Issue.5
, pp. 961-973
-
-
Roulois, D.1
Loo Yau, H.2
Singhania, R.3
Wang, Y.4
Danesh, A.5
Shen, S.Y.6
-
39
-
-
84961226039
-
Immunotherapy: PD-1 says goodbye, TIM-3 says hello
-
Romero D. Immunotherapy: PD-1 says goodbye, TIM-3 says hello. Nat Rev Clin Oncol (2016) 13(4):202-3. doi:10.1038/nrclinonc.2016.40
-
(2016)
Nat Rev Clin Oncol
, vol.13
, Issue.4
, pp. 202-203
-
-
Romero, D.1
-
40
-
-
84890130945
-
Alterations of immune response of non-small cell lung cancer with azacytidine
-
Wrangle J, Wang W, Koch A, Easwaran H, Mohammad HP, Vendetti F, et al. Alterations of immune response of non-small cell lung cancer with azacytidine. Oncotarget (2013) 4(11):2067-79. doi:10.18632/oncotarget.1542
-
(2013)
Oncotarget
, vol.4
, Issue.11
, pp. 2067-2079
-
-
Wrangle, J.1
Wang, W.2
Koch, A.3
Easwaran, H.4
Mohammad, H.P.5
Vendetti, F.6
-
41
-
-
84958555198
-
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
-
Koyama S, Akbay EA, Li YY, Herter-Sprie GS, Buczkowski KA, Richards WG, et al. Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints. Nat Commun (2016) 7:10501. doi:10.1038/ncomms10501
-
(2016)
Nat Commun
, vol.7
, pp. 10501
-
-
Koyama, S.1
Akbay, E.A.2
Li, Y.Y.3
Herter-Sprie, G.S.4
Buczkowski, K.A.5
Richards, W.G.6
-
42
-
-
0025338920
-
LAG-3, a novel lymphocyte activation gene closely related to CD4
-
Triebel F, Jitsukawa S, Baixeras E, Roman-Roman S, Genevee C, Viegas-Pequignot E, et al. LAG-3, a novel lymphocyte activation gene closely related to CD4. J Exp Med (1990) 171(5):1393-405. doi:10.1084/jem.171.5.1393
-
(1990)
J Exp Med
, vol.171
, Issue.5
, pp. 1393-1405
-
-
Triebel, F.1
Jitsukawa, S.2
Baixeras, E.3
Roman-Roman, S.4
Genevee, C.5
Viegas-Pequignot, E.6
-
43
-
-
78650208859
-
The CD4-like molecule LAG-3, biology and therapeutic applications
-
Sierro S, Romero P, Speiser DE. The CD4-like molecule LAG-3, biology and therapeutic applications. Expert Opin Ther Targets (2011) 15(1):91-101. doi:10.1517/14712598.2011.540563
-
(2011)
Expert Opin Ther Targets
, vol.15
, Issue.1
, pp. 91-101
-
-
Sierro, S.1
Romero, P.2
Speiser, D.E.3
-
44
-
-
5644263642
-
Role of LAG-3 in regulatory T cells
-
Huang CT, Workman CJ, Flies D, Pan X, Marson AL, Zhou G, et al. Role of LAG-3 in regulatory T cells. Immunity (2004) 21(4):503-13. doi:10.1016/j.immuni.2004.08.010
-
(2004)
Immunity
, vol.21
, Issue.4
, pp. 503-513
-
-
Huang, C.T.1
Workman, C.J.2
Flies, D.3
Pan, X.4
Marson, A.L.5
Zhou, G.6
-
45
-
-
84863115998
-
Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape
-
Woo SR, Turnis ME, Goldberg MV, Bankoti J, Selby M, Nirschl CJ, et al. Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res (2012) 72(4):917-27. doi:10.1158/0008-5472.CAN-11-1620
-
(2012)
Cancer Res
, vol.72
, Issue.4
, pp. 917-927
-
-
Woo, S.R.1
Turnis, M.E.2
Goldberg, M.V.3
Bankoti, J.4
Selby, M.5
Nirschl, C.J.6
-
46
-
-
77952343328
-
Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer
-
Matsuzaki J, Gnjatic S, Mhawech-Fauceglia P, Beck A, Miller A, Tsuji T, et al. Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer. Proc Natl Acad Sci U S A (2010) 107(17):7875-80. doi:10.1073/pnas.1003345107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.17
, pp. 7875-7880
-
-
Matsuzaki, J.1
Gnjatic, S.2
Mhawech-Fauceglia, P.3
Beck, A.4
Miller, A.5
Tsuji, T.6
-
47
-
-
80455127305
-
Phase I safety and pharmacokinetic study of bavituximab, a chimeric phosphatidylserine-targeting monoclonal antibody, in patients with advanced solid tumors
-
Gerber DE, Stopeck AT, Wong L, Rosen LS, Thorpe PE, Shan JS, et al. Phase I safety and pharmacokinetic study of bavituximab, a chimeric phosphatidylserine-targeting monoclonal antibody, in patients with advanced solid tumors. Clin Cancer Res (2011) 17(21):6888-96. doi:10.1158/1078-0432.CCR-11-1074
-
(2011)
Clin Cancer Res
, vol.17
, Issue.21
, pp. 6888-6896
-
-
Gerber, D.E.1
Stopeck, A.T.2
Wong, L.3
Rosen, L.S.4
Thorpe, P.E.5
Shan, J.S.6
-
48
-
-
20144374032
-
A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice
-
Huang X, Bennett M, Thorpe PE. A monoclonal antibody that binds anionic phospholipids on tumor blood vessels enhances the antitumor effect of docetaxel on human breast tumors in mice. Cancer Res (2005) 65(10):4408-16. doi:10.1158/0008-5472.CAN-05-0031
-
(2005)
Cancer Res
, vol.65
, Issue.10
, pp. 4408-4416
-
-
Huang, X.1
Bennett, M.2
Thorpe, P.E.3
-
49
-
-
4344597636
-
Phosphatidylserine regulates the maturation of human dendritic cells
-
Chen X, Doffek K, Sugg SL, Shilyansky J. Phosphatidylserine regulates the maturation of human dendritic cells. J Immunol (2004) 173(5):2985-94. doi:10.4049/jimmunol.173.5.2985
-
(2004)
J Immunol
, vol.173
, Issue.5
, pp. 2985-2994
-
-
Chen, X.1
Doffek, K.2
Sugg, S.L.3
Shilyansky, J.4
-
50
-
-
84971617618
-
Docetaxel combined with bavituximab in previously treated, advanced nonsquamous non-small-cell lung cancer
-
Gerber DE, Spigel DR, Giorgadze D, Shtivelband M, Ponomarova OV, Shan JS, et al. Docetaxel combined with bavituximab in previously treated, advanced nonsquamous non-small-cell lung cancer. Clin Lung Cancer (2016) 17(3):169-76. doi:10.1016/j.cllc.2016.02.003
-
(2016)
Clin Lung Cancer
, vol.17
, Issue.3
, pp. 169-176
-
-
Gerber, D.E.1
Spigel, D.R.2
Giorgadze, D.3
Shtivelband, M.4
Ponomarova, O.V.5
Shan, J.S.6
-
51
-
-
0033990826
-
Human placental indoleamine 2,3-dioxygenase: cellular localization and characterization of an enzyme preventing fetal rejection
-
Kudo Y, Boyd CA. Human placental indoleamine 2,3-dioxygenase: cellular localization and characterization of an enzyme preventing fetal rejection. Biochim Biophys Acta (2000) 1500(1):119-24. doi:10.1016/S0925-4439(99)00096-4
-
(2000)
Biochim Biophys Acta
, vol.1500
, Issue.1
, pp. 119-124
-
-
Kudo, Y.1
Boyd, C.A.2
-
52
-
-
0022354604
-
Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme
-
Yamazaki F, Kuroiwa T, Takikawa O, Kido R. Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme. Biochem J (1985) 230(3):635-8. doi:10.1042/bj2300635
-
(1985)
Biochem J
, vol.230
, Issue.3
, pp. 635-638
-
-
Yamazaki, F.1
Kuroiwa, T.2
Takikawa, O.3
Kido, R.4
-
53
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science (1998) 281(5380):1191-3. doi:10.1126/science.281.5380.1191
-
(1998)
Science
, vol.281
, Issue.5380
, pp. 1191-1193
-
-
Munn, D.H.1
Zhou, M.2
Attwood, J.T.3
Bondarev, I.4
Conway, S.J.5
Marshall, B.6
-
54
-
-
1542374723
-
CDllc+ cells modulate pulmonary immune responses by production of indoleamine 2,3-dioxygenase
-
Swanson KA, Zheng Y, Heidler KM, Mizobuchi T, Wilkes DS. CDllc+ cells modulate pulmonary immune responses by production of indoleamine 2,3-dioxygenase. Am J Respir Cell Mol Biol (2004) 30(3):311-8. doi:10.1165/rcmb.2003-0268OC
-
(2004)
Am J Respir Cell Mol Biol
, vol.30
, Issue.3
, pp. 311-318
-
-
Swanson, K.A.1
Zheng, Y.2
Heidler, K.M.3
Mizobuchi, T.4
Wilkes, D.S.5
-
55
-
-
84903816506
-
Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
-
Prendergast GC, Smith C, Thomas S, Mandik-Nayak L, Laury-Kleintop L, Metz R, et al. Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer. Cancer Immunol Immunother (2014) 63(7):721-35. doi:10.1007/s00262-014-1549-4
-
(2014)
Cancer Immunol Immunother
, vol.63
, Issue.7
, pp. 721-735
-
-
Prendergast, G.C.1
Smith, C.2
Thomas, S.3
Mandik-Nayak, L.4
Laury-Kleintop, L.5
Metz, R.6
-
56
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey L, Lao CD, et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med (2015) 373(1):23-34. doi:10.1056/NEJMoa1504030
-
(2015)
N Engl J Med
, vol.373
, Issue.1
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
Grob, J.J.4
Cowey, L.5
Lao, C.D.6
-
57
-
-
84984681480
-
CheckMate 012: safety and efficacy of first-line (1L) nivolumab (nivo; N) and ipilimumab (ipi; I) in advanced (adv) NSCLC
-
Hellmann MDEA. CheckMate 012: safety and efficacy of first-line (1L) nivolumab (nivo; N) and ipilimumab (ipi; I) in advanced (adv) NSCLC. J Clin Oncol (2016) 34(Suppl):abstr 3001.
-
(2016)
J Clin Oncol
, vol.34
-
-
Hellmann, M.D.E.A.1
-
58
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med (2002) 346(2):92-8. doi:10.1056/NEJMoa011954
-
(2002)
N Engl J Med
, vol.346
, Issue.2
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
Langer, C.4
Sandler, A.5
Krook, J.6
-
59
-
-
67650281462
-
Phase III study by the Norwegian lung cancer study group: pemetrexed plus carboplatin compared with gemcitabine plus carboplatin as first-line chemotherapy in advanced non-small-cell lung cancer
-
Grønberg BH, Bremnes RM, Fløtten O, Amundsen T, Brunsvig PF, Hjelde HH, et al. Phase III study by the Norwegian lung cancer study group: pemetrexed plus carboplatin compared with gemcitabine plus carboplatin as first-line chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol (2009) 27(19):3217-24. doi:10.1200/JCO.2008.20.9114
-
(2009)
J Clin Oncol
, vol.27
, Issue.19
, pp. 3217-3224
-
-
Grønberg, B.H.1
Bremnes, R.M.2
Fløtten, O.3
Amundsen, T.4
Brunsvig, P.F.5
Hjelde, H.H.6
-
60
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, Brahmer J, Schiller JH, Dowalti A, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med (2006) 355(24):2542-50. doi:10.1056/NEJMoa061884
-
(2006)
N Engl J Med
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowalti, A.6
-
61
-
-
84947444749
-
Pembrolizumab (pembro; MK-3475) plus platinum doublet chemotherapy (PDC) as front-line therapy for advanced non-small cell lung cancer (NSCLC): KEYNOTE-021 cohorts A and C
-
Papadimitrakopoulou V, Patnaik A, Borghaei H, Stevenson J, Gandhi L, Gubens MA, et al. Pembrolizumab (pembro; MK-3475) plus platinum doublet chemotherapy (PDC) as front-line therapy for advanced non-small cell lung cancer (NSCLC): KEYNOTE-021 cohorts A and C. J Clin Oncol (2015) 33(Suppl):abstr 8031.
-
(2015)
J Clin Oncol
, vol.33
-
-
Papadimitrakopoulou, V.1
Patnaik, A.2
Borghaei, H.3
Stevenson, J.4
Gandhi, L.5
Gubens, M.A.6
-
62
-
-
85040257501
-
136O: osimertinib combined with durvalumab in EGFR-mutant non-small cell lung cancer: results from the TATTON phase Ib trial
-
Ahn MJ, Yang J, Yu H, Saka H, Ramalingam S, Goto K, et al. 136O: osimertinib combined with durvalumab in EGFR-mutant non-small cell lung cancer: results from the TATTON phase Ib trial. J Thorac Oncol (2016) 11(4):S115. doi:10.1016/S1556-0864(16)30246-5
-
(2016)
J Thorac Oncol
, vol.11
, Issue.4
, pp. S115
-
-
Ahn, M.J.1
Yang, J.2
Yu, H.3
Saka, H.4
Ramalingam, S.5
Goto, K.6
-
63
-
-
84964573640
-
Management of immune checkpoint blockade dysimmune toxicities: a collaborative position paper
-
Champiat S, Lambotte O, Barreau E, Belkhir R, Berdelou A, Carbonnel F, et al. Management of immune checkpoint blockade dysimmune toxicities: a collaborative position paper. Ann Oncol (2016) 27(4):559-74. doi:10.1093/annonc/mdv623
-
(2016)
Ann Oncol
, vol.27
, Issue.4
, pp. 559-574
-
-
Champiat, S.1
Lambotte, O.2
Barreau, E.3
Belkhir, R.4
Berdelou, A.5
Carbonnel, F.6
-
64
-
-
84874605864
-
Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
-
Ribas A, Kefford R, Marshall MA, Punt CJ, Haanen JB, Marmol M, et al. Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. J Clin Oncol (2013) 31(5):616-22. doi:10.1200/JCO.2012.44.6112
-
(2013)
J Clin Oncol
, vol.31
, Issue.5
, pp. 616-622
-
-
Ribas, A.1
Kefford, R.2
Marshall, M.A.3
Punt, C.J.4
Haanen, J.B.5
Marmol, M.6
-
65
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
-
Weber JS, D'Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol (2015) 16(4):375-84. doi:10.1016/S1470-2045(15)70076-8
-
(2015)
Lancet Oncol
, vol.16
, Issue.4
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
Hodi, F.S.4
Gutzmer, R.5
Neyns, B.6
-
66
-
-
84983652291
-
Nivolumab monotherapy for first-line treatment of advanced non-small-cell lung cancer
-
Gettinger S, Rizvi NA, Chow LQ, Borghaei H, Brahmer J, Ready N, et al. Nivolumab monotherapy for first-line treatment of advanced non-small-cell lung cancer. J Clin Oncol (2016) 34(25):2980-7. doi:10.1200/jco.2016.66.9929
-
(2016)
J Clin Oncol
, vol.34
, Issue.25
, pp. 2980-2987
-
-
Gettinger, S.1
Rizvi, N.A.2
Chow, L.Q.3
Borghaei, H.4
Brahmer, J.5
Ready, N.6
|