-
1
-
-
0037203867
-
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
-
DOI 10.1038/415536a
-
Monney L, Sabatos CA, Gaglia JL, et al. Th1-specific cell surface protein TIM-3 regulates macrophage activation and severity of an autoimmune disease. Nature. 2002;415:536-541. (Pubitemid 34130609)
-
(2002)
Nature
, vol.415
, Issue.6871
, pp. 536-541
-
-
Monney, L.1
Sabatos, C.A.2
Gaglia, J.L.3
Ryu, A.4
Waldner, H.5
Chernova, T.6
Manning, S.7
Greenfield, E.A.8
Coyle, A.J.9
Sobel, R.A.10
Freeman, G.J.11
Kuchroo, V.K.12
-
2
-
-
58149277359
-
TIM-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
Jones RB, Ndhlovu LC, Barbour JD, et al. TIM-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J Exp Med. 2008;205:2763-2779.
-
(2008)
J Exp Med
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
Ndhlovu, L.C.2
Barbour, J.D.3
-
3
-
-
0242539820
-
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
-
DOI 10.1038/ni988
-
Sabatos CA, Chakravarti S, Cha E, et al. Interaction of TIM-3 and TIM-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol. 2003;4:1102-1110. (Pubitemid 37428038)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1102-1110
-
-
Sabatos, C.A.1
Chakravarti, S.2
Cha, E.3
Schubart, A.4
Sanchez-Fueyo, A.5
Zheng, X.X.6
Coyle, A.J.7
Strom, T.B.8
Freeman, G.J.9
Kuchroo, V.K.10
-
4
-
-
33749131686
-
+ T cells in murine acute graft-versus-host disease
-
Oikawa T, Kamimura Y, Akiba H, et al. Preferential involvement of TIM-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease. J Immunol. 2006;177:4281-4287. (Pubitemid 44469756)
-
(2006)
Journal of Immunology
, vol.177
, Issue.7
, pp. 4281-4287
-
-
Oikawa, T.1
Kamimura, Y.2
Akiba, H.3
Yagita, H.4
Okumura, K.5
Takahashi, H.6
Zeniya, M.7
Tajiri, H.8
Azuma, M.9
-
5
-
-
44449147392
-
TIM-3 polymorphisms in type 1 diabetes families
-
Bruck P, Ramos-Lopez E, Bartsch W, et al. TIM-3 polymorphisms in type 1 diabetes families. J Hum Genet. 2008;53:559-564.
-
(2008)
J Hum Genet
, vol.53
, pp. 559-564
-
-
Bruck, P.1
Ramos-Lopez, E.2
Bartsch, W.3
-
6
-
-
44449135110
-
Lack of TIM-3 immunoregulation in multiple sclerosis
-
Yang L, Anderson DE, Kuchroo J, et al. Lack of TIM-3 immunoregulation in multiple sclerosis. J Immunol. 2008;180:4409-4414.
-
(2008)
J Immunol
, vol.180
, pp. 4409-4414
-
-
Yang, L.1
Anderson, D.E.2
Kuchroo, J.3
-
7
-
-
2442704124
-
T cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis
-
Khademi M, Illes Z, Gielen AW, et al. T Cell Ig- and mucin-domain- containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis. J Immunol. 2004;172:7169-7176. (Pubitemid 38669161)
-
(2004)
Journal of Immunology
, vol.172
, Issue.11
, pp. 7169-7176
-
-
Khademi, M.1
Illes, Z.2
Gielen, A.W.3
Marta, M.4
Takazawa, N.5
Baecher-Allan, C.6
Brundin, L.7
Hannerz, J.8
Martin, C.9
Harris, R.A.10
Hafler, D.A.11
Kuchroo, V.K.12
Olsson, T.13
Piehl, F.14
Wallstrom, E.15
-
8
-
-
33947224207
-
TIM-3 is expressed in melanoma cells and is upregulated in TGF-beta stimulated mast cells
-
DOI 10.1038/sj.jid.5700616, PII 5700616
-
Wiener Z, Kohalmi B, Pocza P, et al. TIM-3 is expressed in melanoma cells and is upregulated in TGF-beta stimulated mast cells. J Invest Dermatol. 2007;127:906-914. (Pubitemid 46434647)
-
(2007)
Journal of Investigative Dermatology
, vol.127
, Issue.4
, pp. 906-914
-
-
Wiener, Z.1
Kohalmi, B.2
Pocza, P.3
Jeager, J.4
Tolgyesi, G.5
Toth, S.6
Gorbe, E.7
Papp, Z.8
Falus, A.9
-
9
-
-
0642313736
-
State of the art: Lung cancer in China
-
Houwen L. State of the art: lung cancer in China. Ann Thorac Cardiovasc Surg. 2003;9:147-148.
-
(2003)
Ann Thorac Cardiovasc Surg
, vol.9
, pp. 147-148
-
-
Houwen, L.1
-
10
-
-
33750069402
-
Advances in chemotherapy of non-small cell lung cancer
-
DOI 10.1378/chest.130.4.1211
-
Molina JR, Adjei AA, Jett JR. Advances in chemotherapy of non-small cell lung cancer. Chest. 2006;130:1211-1219. (Pubitemid 44583755)
-
(2006)
Chest
, vol.130
, Issue.4
, pp. 1211-1219
-
-
Molina, J.R.1
Adjei, A.A.2
Jett, J.R.3
-
11
-
-
0037050355
-
Lung cancer - Time to move on from chemotherapy
-
DOI 10.1056/NEJM200201103460211
-
Carney DN. Lung cancer: time to move on from chemotherapy. N Engl J Med. 2002;346:126-128. (Pubitemid 34438905)
-
(2002)
New England Journal of Medicine
, vol.346
, Issue.2
, pp. 126-128
-
-
Carney, D.N.1
-
12
-
-
0030982728
-
Non-small cell lung cancer: Clinical value of new biological predictors
-
PII S0169500297006399
-
Graziano SL. Non-small cell lung cancer: clinical value of new biological predictors. Lung Cancer. 1997;17(suppl 1):S37-S58. (Pubitemid 127673771)
-
(1997)
Lung Cancer
, vol.17
, Issue.SUPPL.1
-
-
Graziano, S.L.1
-
13
-
-
0027440644
-
Prognostic significance of the proliferation index in surgically resected non-small-cell lung cancer
-
Pence JC, Kerns BJ, Dodge RK, et al. Prognostic significance of the proliferation index in surgically resected non-small-cell lung cancer. Arch Surg. 1993;128:1382-1390. (Pubitemid 23360034)
-
(1993)
Archives of Surgery
, vol.128
, Issue.12
, pp. 1382-1390
-
-
Pence, J.C.1
Kerns, B.-J.M.2
Dodge, R.K.3
Iglehart, J.D.4
-
14
-
-
0030743447
-
The expression of the CD44 variant exon 6 is associated with lymph node metastasis in non-small cell lung cancer
-
Miyoshi T, Kondo K, Hino N, et al. The expression of the CD44 variant exon 6 is associated with lymph node metastasis in non-small cell lung cancer. Clin Cancer Res. 1997;3:1289-1297. (Pubitemid 27362389)
-
(1997)
Clinical Cancer Research
, vol.3
, Issue.8
, pp. 1289-1297
-
-
Miyoshi, T.1
Kondo, K.2
Hino, N.3
Uyama, T.4
Monden, Y.5
-
15
-
-
0028840535
-
Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer
-
Rusch V, Klimstra D, Venkatraman E, et al. Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer. Cancer Res. 1995;55:5038-5042.
-
(1995)
Cancer Res
, vol.55
, pp. 5038-5042
-
-
Rusch, V.1
Klimstra, D.2
Venkatraman, E.3
-
16
-
-
20244388951
-
Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: Clinical implications
-
Kwiatkowski DJ, Harpole DH Jr, Godleski J, et al. Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications. J Clin Oncol. 1998;16:2468-2477. (Pubitemid 28309043)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.7
, pp. 2468-2477
-
-
Kwiatkowski, D.J.1
Harpole Jr., D.H.2
Godleski, J.3
Herndon II, J.E.4
Shieh, D.-B.5
Richards, W.6
Blanco, R.7
Xu, H.-J.8
Strauss, G.M.9
Sugarbaker, D.J.10
-
17
-
-
0019426595
-
Lung abscess complicating transbronchial biopsy of a mass lesion
-
Hsu JT, Barrett CR Jr. Lung abscess complicating transbronchial biopsy of a mass lesion. Chest. 1981;80:230-232. (Pubitemid 11051805)
-
(1981)
Chest
, vol.80
, Issue.2
, pp. 230-232
-
-
Hsu, J.T.1
Barrett Jr., C.R.2
-
18
-
-
0030801343
-
Respiratory effort sensation during exercise with induced expiratory- flow limitation in healthy humans
-
Kayser B, Sliwinski P, Yan S, et al. Respiratory effort sensation during exercise with induced expiratory-flow limitation in healthy humans. J Appl Physiol. 1997;83:936-947. (Pubitemid 27392316)
-
(1997)
Journal of Applied Physiology
, vol.83
, Issue.3
, pp. 936-947
-
-
Kayser, B.1
Sliwinski, P.2
Yan, S.3
Tobiasz, M.4
Macklem, P.T.5
-
19
-
-
70349248367
-
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
-
Hastings WD, Anderson DE, Kassam N, et al. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol. 2009;39:2492-2501.
-
(2009)
Eur J Immunol
, vol.39
, pp. 2492-2501
-
-
Hastings, W.D.1
Anderson, D.E.2
Kassam, N.3
-
20
-
-
65549168745
-
Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation
-
Nakayama M, Akiba H, Takeda K, et al. Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation. Blood. 2009;113:3821-3830.
-
(2009)
Blood
, vol.113
, pp. 3821-3830
-
-
Nakayama, M.1
Akiba, H.2
Takeda, K.3
-
21
-
-
36248967595
-
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
-
DOI 10.1126/science.1148536
-
Anderson AC, Anderson DE, Bregoli L, et al. Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science. 2007;318:1141-1143. (Pubitemid 350134897)
-
(2007)
Science
, vol.318
, Issue.5853
, pp. 1141-1143
-
-
Anderson, A.C.1
Anderson, D.E.2
Bregoli, L.3
Hastings, W.D.4
Kassam, N.5
Lei, C.6
Chandwaskar, R.7
Karman, J.8
Su, E.W.9
Hirashima, M.10
Bruce, J.N.11
Kane, L.P.12
Kuchroo, V.K.13
Hafler, D.A.14
-
22
-
-
77549086947
-
T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B
-
Ju Y, Hou N, Meng J, et al. T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B. J Hepatol. 2010;52:322-329.
-
(2010)
J Hepatol
, vol.52
, pp. 322-329
-
-
Ju, Y.1
Hou, N.2
Meng, J.3
-
23
-
-
41249096396
-
The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cell and prolongs survival of skin graft
-
Wang F, He W, Zhou H, et al. The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cell and prolongs survival of skin graft. Cell Immunol. 2007;250:68-74.
-
(2007)
Cell Immunol
, vol.250
, pp. 68-74
-
-
Wang, F.1
He, W.2
Zhou, H.3
-
24
-
-
0242708767
-
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
-
DOI 10.1038/ni987
-
Sanchez-Fueyo A, Tian J, Picarella D, et al. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol. 2003;4:1093-1101. (Pubitemid 37428037)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1093-1101
-
-
Sanchez-Fueyo, A.1
Tian, J.2
Picarella, D.3
Domenig, C.4
Zheng, X.X.5
Sabatos, C.A.6
Manlongat, N.7
Bender, O.8
Kamradt, T.9
Kuchroo, V.K.10
Gutierrez-Ramos, J.-C.11
Coyle, A.J.12
Strom, T.B.13
-
25
-
-
34948848135
-
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells
-
DOI 10.1182/blood-2006-11-058800
-
Nakae S, Iikura M, Suto H, et al. TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells. Blood. 2007;110:2565-2568. (Pubitemid 47523180)
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2565-2568
-
-
Nakae, S.1
Iikura, M.2
Suto, H.3
Akiba, H.4
Umetsu, D.T.5
DeKruyff, R.H.6
Saito, H.7
Galli, S.J.8
-
26
-
-
0035281783
-
Transforming growth factor-beta1 level correlates with angiogenesis, tumor progression, and prognosis in patients with nonsmall cell lung carcinoma
-
Hasegawa Y, Takanashi S, Kanehira Y, et al. Transforming growth factor-beta1 level correlates with angiogenesis, tumor progression, and prognosis in patients with nonsmall cell lung carcinoma. Cancer. 2001;91:964-971.
-
(2001)
Cancer
, vol.91
, pp. 964-971
-
-
Hasegawa, Y.1
Takanashi, S.2
Kanehira, Y.3
-
27
-
-
0030869705
-
Transforming growth factor beta1, interleukin-8 and interleukin-1, in non- small-cell lung tumors
-
Colasante A, Mascetra N, Brunetti M, et al. Transforming growth factor beta 1, interleukin-8 and interleukin-1, in non-small-cell lung tumors. Am J Respir Crit Care Med. 1997;156:968-973. (Pubitemid 27396443)
-
(1997)
American Journal of Respiratory and Critical Care Medicine
, vol.156
, Issue.3 I
, pp. 968-973
-
-
Colasante, A.1
Mascetra, N.2
Brunetti, M.3
Lattanzio, C.4
Diodoro, M.5
Caltagirone, S.6
Musiani, P.7
Aiello, F.B.8
-
28
-
-
65549147768
-
Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection
-
Ju Y, Hou N, Zhang XN, et al. Blockade of Tim-3 pathway ameliorates interferon-gamma production from hepatic CD8+ T cells in a mouse model of hepatitis B virus infection. Cell Mol Immunol. 2009;6:35-43.
-
(2009)
Cell Mol Immunol
, vol.6
, pp. 35-43
-
-
Ju, Y.1
Hou, N.2
Zhang, X.N.3
-
29
-
-
77949524521
-
Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion
-
Huang X, Bai X, Cao Y, et al. Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion. J Exp Med. 2010;207:505-520.
-
(2010)
J Exp Med
, vol.207
, pp. 505-520
-
-
Huang, X.1
Bai, X.2
Cao, Y.3
-
30
-
-
0023729689
-
Role of tumorinfiltrating lymphocytes in the host defense mechanism against lung cancer
-
Yasumoto K, Takeo S, Yano T, et al. Role of tumorinfiltrating lymphocytes in the host defense mechanism against lung cancer. J Surg Oncol. 1988;38:221-226.
-
(1988)
J Surg Oncol
, vol.38
, pp. 221-226
-
-
Yasumoto, K.1
Takeo, S.2
Yano, T.3
-
31
-
-
76149124214
-
A high number of CD8+ T cells infiltrated in NSCLC tissues is associated with a favorable prognosis
-
Zhuang X, Xia X, Wang C, et al. A high number of CD8+ T cells infiltrated in NSCLC tissues is associated with a favorable prognosis. Appl Immunohistochem Mol Morphol. 2010;18:24-28.
-
(2010)
Appl Immunohistochem Mol Morphol
, vol.18
, pp. 24-28
-
-
Zhuang, X.1
Xia, X.2
Wang, C.3
|