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Volumn 532, Issue , 2017, Pages 95-99

Genome-scale CRISPR pooled screens

Author keywords

Cancer; Cas9; CRISPR; Genetic screens; Genome engineering; Noncoding

Indexed keywords

ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GAIN OF FUNCTION MUTATION; GENOME; LOSS OF FUNCTION MUTATION; PRIORITY JOURNAL; CRISPR CAS SYSTEM; GENE EDITING; GENE TARGETING; GENETIC ENGINEERING; GENETICS; HUMAN; HUMAN GENOME; PROCEDURES;

EID: 85006341892     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2016.05.014     Document Type: Article
Times cited : (46)

References (36)
  • 2
    • 84941309166 scopus 로고    scopus 로고
    • Morphological profiles of RNAi-induced gene knockdown are highly reproducible but dominated by seed effects
    • Singh, S., Wu, X., Ljosa, V., Bray, M.-A., Piccioni, F., Root, D.E., et al. Morphological profiles of RNAi-induced gene knockdown are highly reproducible but dominated by seed effects. PLoS One, 10(7), 2015, e0131370.
    • (2015) PLoS One , vol.10 , Issue.7 , pp. e0131370
    • Singh, S.1    Wu, X.2    Ljosa, V.3    Bray, M.-A.4    Piccioni, F.5    Root, D.E.6
  • 4
    • 84892749369 scopus 로고    scopus 로고
    • Genetic screens in human cells using the CRISPR–Cas9 system
    • Wang, T., Wei, J.J., Sabatini, D.M., Lander, E.S., Genetic screens in human cells using the CRISPR–Cas9 system. Science 343 (2014), 80–84.
    • (2014) Science , vol.343 , pp. 80-84
    • Wang, T.1    Wei, J.J.2    Sabatini, D.M.3    Lander, E.S.4
  • 5
    • 16444385662 scopus 로고    scopus 로고
    • Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements
    • Mojica, F.J.M., Díez-Villaseñor, C., García-Martínez, J., Soria, E., Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements. J. Mol. Evol. 60 (2005), 174–182.
    • (2005) J. Mol. Evol. , vol.60 , pp. 174-182
    • Mojica, F.J.M.1    Díez-Villaseñor, C.2    García-Martínez, J.3    Soria, E.4
  • 6
    • 15844390228 scopus 로고    scopus 로고
    • CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies
    • Pourcel, C., Salvignol, G., Vergnaud, G., CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. Microbiol. Read. UK 151 (2005), 653–663.
    • (2005) Microbiol. Read. UK , vol.151 , pp. 653-663
    • Pourcel, C.1    Salvignol, G.2    Vergnaud, G.3
  • 7
    • 34047118522 scopus 로고    scopus 로고
    • CRISPR provides acquired resistance against viruses in prokaryotes
    • Barrangou, R., Fremaux, C., Deveau, H., Richards, M., Boyaval, P., Moineau, S., et al. CRISPR provides acquired resistance against viruses in prokaryotes. Science 315 (2007), 1709–1712.
    • (2007) Science , vol.315 , pp. 1709-1712
    • Barrangou, R.1    Fremaux, C.2    Deveau, H.3    Richards, M.4    Boyaval, P.5    Moineau, S.6
  • 9
    • 84873729095 scopus 로고    scopus 로고
    • Multiplex genome engineering using CRISPR/Cas systems
    • Cong, L., Ran, F.A., Cox, D., Lin, S., Barretto, R., Habib, N., et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339 (2013), 819–823.
    • (2013) Science , vol.339 , pp. 819-823
    • Cong, L.1    Ran, F.A.2    Cox, D.3    Lin, S.4    Barretto, R.5    Habib, N.6
  • 10
  • 11
    • 84902096048 scopus 로고    scopus 로고
    • Development and applications of CRISPR–Cas9 for genome engineering
    • Hsu, P.D., Lander, E.S., Zhang, F., Development and applications of CRISPR–Cas9 for genome engineering. Cell 157 (2014), 1262–1278.
    • (2014) Cell , vol.157 , pp. 1262-1278
    • Hsu, P.D.1    Lander, E.S.2    Zhang, F.3
  • 12
    • 84898665052 scopus 로고    scopus 로고
    • Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
    • Koike-Yusa, H., Li, Y., Tan, E.-P., Velasco-Herrera, M.C., Yusa, K., Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library. Nat. Biotechnol. 32 (2014), 267–273.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 267-273
    • Koike-Yusa, H.1    Li, Y.2    Tan, E.-P.3    Velasco-Herrera, M.C.4    Yusa, K.5
  • 13
    • 84905262730 scopus 로고    scopus 로고
    • Improved vectors and genome-wide libraries for CRISPR screening
    • Sanjana, N.E., Shalem, O., Zhang, F., Improved vectors and genome-wide libraries for CRISPR screening. Nat. Methods 11 (2014), 783–784.
    • (2014) Nat. Methods , vol.11 , pp. 783-784
    • Sanjana, N.E.1    Shalem, O.2    Zhang, F.3
  • 14
    • 84930939029 scopus 로고    scopus 로고
    • Discovery of cancer drug targets by CRISPR–Cas9 screening of protein domains
    • Shi, J., Wang, E., Milazzo, J.P., Wang, Z., Kinney, J.B., Vakoc, C.R., Discovery of cancer drug targets by CRISPR–Cas9 screening of protein domains. Nat. Biotechnol. 33 (2015), 661–667.
    • (2015) Nat. Biotechnol. , vol.33 , pp. 661-667
    • Shi, J.1    Wang, E.2    Milazzo, J.P.3    Wang, Z.4    Kinney, J.B.5    Vakoc, C.R.6
  • 15
    • 84947048286 scopus 로고    scopus 로고
    • A CRISPR-based screen identifies genes essential for West-Nile-Virus-induced cell death
    • Ma, H., Dang, Y., Wu, Y., Jia, G., Anaya, E., Zhang, J., et al. A CRISPR-based screen identifies genes essential for West-Nile-Virus-induced cell death. Cell Rep. 12 (2015), 673–683.
    • (2015) Cell Rep. , vol.12 , pp. 673-683
    • Ma, H.1    Dang, Y.2    Wu, Y.3    Jia, G.4    Anaya, E.5    Zhang, J.6
  • 16
    • 84938232611 scopus 로고    scopus 로고
    • An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis
    • Birsoy, K., Wang, T., Chen, W.W., Freinkman, E., Abu-Remaileh, M., Sabatini, D.M., An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis. Cell 162 (2015), 540–551.
    • (2015) Cell , vol.162 , pp. 540-551
    • Birsoy, K.1    Wang, T.2    Chen, W.W.3    Freinkman, E.4    Abu-Remaileh, M.5    Sabatini, D.M.6
  • 17
    • 84947471999 scopus 로고    scopus 로고
    • Identification and characterization of essential genes in the human genome
    • Wang, T., Birsoy, K., Hughes, N.W., Krupczak, K.M., Post, Y., Wei, J.J., et al. Identification and characterization of essential genes in the human genome. Science 350 (2015), 1096–1101.
    • (2015) Science , vol.350 , pp. 1096-1101
    • Wang, T.1    Birsoy, K.2    Hughes, N.W.3    Krupczak, K.M.4    Post, Y.5    Wei, J.J.6
  • 18
    • 84949233942 scopus 로고    scopus 로고
    • High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
    • Hart, T., Chandrashekhar, M., Aregger, M., Steinhart, Z., Brown, K.R., MacLeod, G., et al. High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities. Cell 163 (2015), 1515–1526.
    • (2015) Cell , vol.163 , pp. 1515-1526
    • Hart, T.1    Chandrashekhar, M.2    Aregger, M.3    Steinhart, Z.4    Brown, K.R.5    MacLeod, G.6
  • 19
    • 84952872645 scopus 로고    scopus 로고
    • Genome-wide CRISPR–Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells
    • Toledo, C.M., Ding, Y., Hoellerbauer, P., Davis, R.J., Basom, R., Girard, E.J., et al. Genome-wide CRISPR–Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in glioblastoma stem-like cells. Cell Rep. 13 (2015), 2425–2439.
    • (2015) Cell Rep. , vol.13 , pp. 2425-2439
    • Toledo, C.M.1    Ding, Y.2    Hoellerbauer, P.3    Davis, R.J.4    Basom, R.5    Girard, E.J.6
  • 20
    • 84925008880 scopus 로고    scopus 로고
    • Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis
    • Chen, S., Sanjana, N.E., Zheng, K., Shalem, O., Lee, K., Shi, X., et al. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell 160 (2015), 1246–1260.
    • (2015) Cell , vol.160 , pp. 1246-1260
    • Chen, S.1    Sanjana, N.E.2    Zheng, K.3    Shalem, O.4    Lee, K.5    Shi, X.6
  • 21
    • 84938744950 scopus 로고    scopus 로고
    • A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks
    • Parnas, O., Jovanovic, M., Eisenhaure, T.M., Herbst, R.H., Dixit, A., Ye, C.J., et al. A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks. Cell 162 (2015), 675–686.
    • (2015) Cell , vol.162 , pp. 675-686
    • Parnas, O.1    Jovanovic, M.2    Eisenhaure, T.M.3    Herbst, R.H.4    Dixit, A.5    Ye, C.J.6
  • 22
    • 84952931119 scopus 로고    scopus 로고
    • A genome-wide CRISPR screen identifies NEK7 as an essential component of NLRP3 inflammasome activation
    • Schmid-Burgk, J.L., Chauhan, D., Schmidt, T., Ebert, T.S., Reinhardt, J., Endl, E., et al. A genome-wide CRISPR screen identifies NEK7 as an essential component of NLRP3 inflammasome activation. J. Biol. Chem. 291 (2016), 103–109.
    • (2016) J. Biol. Chem. , vol.291 , pp. 103-109
    • Schmid-Burgk, J.L.1    Chauhan, D.2    Schmidt, T.3    Ebert, T.S.4    Reinhardt, J.5    Endl, E.6
  • 23
    • 84923096541 scopus 로고    scopus 로고
    • Genome-scale transcriptional activation by an engineered CRISPR–Cas9 complex
    • Konermann, S., Brigham, M.D., Trevino, A.E., Joung, J., Abudayyeh, O.O., Barcena, C., et al. Genome-scale transcriptional activation by an engineered CRISPR–Cas9 complex. Nature 517 (2015), 583–588.
    • (2015) Nature , vol.517 , pp. 583-588
    • Konermann, S.1    Brigham, M.D.2    Trevino, A.E.3    Joung, J.4    Abudayyeh, O.O.5    Barcena, C.6
  • 24
  • 25
    • 84886047746 scopus 로고    scopus 로고
    • The evolution of melanoma resistance reveals therapeutic opportunities
    • Das Thakur, M., Stuart, D.D., The evolution of melanoma resistance reveals therapeutic opportunities. Cancer Res. 73 (2013), 6106–6110.
    • (2013) Cancer Res. , vol.73 , pp. 6106-6110
    • Das Thakur, M.1    Stuart, D.D.2
  • 26
    • 84870020040 scopus 로고    scopus 로고
    • MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling
    • Huang, S., Hölzel, M., Knijnenburg, T., Schlicker, A., Roepman, P., McDermott, U., et al. MED12 controls the response to multiple cancer drugs through regulation of TGF-β receptor signaling. Cell 151 (2012), 937–950.
    • (2012) Cell , vol.151 , pp. 937-950
    • Huang, S.1    Hölzel, M.2    Knijnenburg, T.3    Schlicker, A.4    Roepman, P.5    McDermott, U.6
  • 27
    • 84875717480 scopus 로고    scopus 로고
    • A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition
    • Whittaker, S.R., Theurillat, J.-P., Van Allen, E., Wagle, N., Hsiao, J., Cowley, G.S., et al. A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition. Cancer Discov. 3 (2013), 350–362.
    • (2013) Cancer Discov. , vol.3 , pp. 350-362
    • Whittaker, S.R.1    Theurillat, J.-P.2    Van Allen, E.3    Wagle, N.4    Hsiao, J.5    Cowley, G.S.6
  • 31
    • 84929001104 scopus 로고    scopus 로고
    • The Genotype–Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
    • GTEx Consortium, The Genotype–Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans. Science 348 (2015), 648–660.
    • (2015) Science , vol.348 , pp. 648-660
    • GTEx Consortium1
  • 32
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • Lein, E.S., Hawrylycz, M.J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., et al. Genome-wide atlas of gene expression in the adult mouse brain. Nature 445 (2007), 168–176.
    • (2007) Nature , vol.445 , pp. 168-176
    • Lein, E.S.1    Hawrylycz, M.J.2    Ao, N.3    Ayres, M.4    Bensinger, A.5    Bernard, A.6
  • 33
    • 84949100864 scopus 로고    scopus 로고
    • Highly specific epigenome editing by CRISPR–Cas9 repressors for silencing of distal regulatory elements
    • Thakore, P.I., D'Ippolito, A.M., Song, L., Safi, A., Shivakumar, N.K., Kabadi, A.M., et al. Highly specific epigenome editing by CRISPR–Cas9 repressors for silencing of distal regulatory elements. Nat. Methods 12 (2015), 1143–1149.
    • (2015) Nat. Methods , vol.12 , pp. 1143-1149
    • Thakore, P.I.1    D'Ippolito, A.M.2    Song, L.3    Safi, A.4    Shivakumar, N.K.5    Kabadi, A.M.6
  • 34
    • 84928924333 scopus 로고    scopus 로고
    • Functional annotation of native enhancers with a Cas9–histone demethylase fusion
    • Kearns, N.A., Pham, H., Tabak, B., Genga, R.M., Silverstein, N.J., Garber, M., et al. Functional annotation of native enhancers with a Cas9–histone demethylase fusion. Nat. Methods 12 (2015), 401–403.
    • (2015) Nat. Methods , vol.12 , pp. 401-403
    • Kearns, N.A.1    Pham, H.2    Tabak, B.3    Genga, R.M.4    Silverstein, N.J.5    Garber, M.6
  • 35
    • 84946925193 scopus 로고    scopus 로고
    • BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
    • Canver, M.C., Smith, E.C., Sher, F., Pinello, L., Sanjana, N.E., Shalem, O., et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature 527 (2015), 192–197.
    • (2015) Nature , vol.527 , pp. 192-197
    • Canver, M.C.1    Smith, E.C.2    Sher, F.3    Pinello, L.4    Sanjana, N.E.5    Shalem, O.6
  • 36
    • 84907257107 scopus 로고    scopus 로고
    • Saturation editing of genomic regions by multiplex homology-directed repair
    • Findlay, G.M., Boyle, E.A., Hause, R.J., Klein, J.C., Shendure, J., Saturation editing of genomic regions by multiplex homology-directed repair. Nature 513 (2014), 120–123.
    • (2014) Nature , vol.513 , pp. 120-123
    • Findlay, G.M.1    Boyle, E.A.2    Hause, R.J.3    Klein, J.C.4    Shendure, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.