Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans

Cell Host and Microbe

Volumn 20, Issue 6, 2016, Pages 822-833

  Oosting, Marije ^a   Kerstholt, Mariska ^a   ter Horst, Rob ^a   Li, Yang ^b   Deelen, Patrick ^b   Smeekens, Sanne ^a   Jaeger, Martin ^a   Lachmandas, Ekta ^a   Vrijmoeth, Hedwig ^a   Lupse, Mihaela ^c   Flonta, Mirela ^c   Cramer, Robert A ^d   Kullberg, Bart Jan ^a   Kumar, Vinod ^b   Xavier, Ramnik ^e,f   Wijmenga, Cisca ^b   Netea, Mihai G ^a   Joosten, Leo A B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

Borrelia burgdorferi; cytokines; glucose metabolism; HIF 1 ; host defense; Lyme disease

Indexed keywords

GAMMA INTERFERON; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 22; INTERLEUKIN 6; LACTIC ACID; TUMOR NECROSIS FACTOR; BACTERIAL DNA; CYTOKINE; GLUCOSE; HIF1A PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; TRANSCRIPTOME;

ARTICLE; BACTERIAL GENETICS; BACTERIAL GENOME; BORRELIA BURGDORFERI; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FUNCTIONAL GENOMICS; GENE FUNCTION; GENE LOCUS; GLYCOLYSIS; HUMAN; IMMUNE RESPONSE; LYME DISEASE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; TRANSCRIPTOMICS; VALIDATION STUDY; WESTERN EUROPEAN; AGE; ANIMAL; BIOSYNTHESIS; BLOOD; CELL LINE; CELL SURVIVAL; CHROMOSOMAL MAPPING; GENETICS; GENOMICS; IMMUNOLOGY; LEUKOCYTE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; T LYMPHOCYTE;

AGE FACTORS; ANIMALS; BLOOD; BORRELIA BURGDORFERI; BORRELIA BURGDORFERI GROUP; CELL LINE; CELL SURVIVAL; CHROMOSOME MAPPING; CYTOKINES; DNA, BACTERIAL; GENOME, BACTERIAL; GENOMICS; GLUCOSE; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-6; INTERLEUKINS; LACTIC ACID; LEUKOCYTES; LYME DISEASE; MICE; MONOCYTES; T-LYMPHOCYTES; TRANSCRIPTOME;

EID: 85006138330     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2016.10.006     Document Type: Article

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