A membrane protease regulates energy production in macrophages by activating hypoxia-inducible factor-1 via a non-proteolytic mechanism

Journal of Biological Chemistry

Volumn 285, Issue 39, 2010, Pages 29951-29964

  Sakamoto, Takeharu ^a   Seiki, Motoharu ^a  

^a THE UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION; PATHOLOGY; PHOSPHORYLATION;

ATP LEVEL; CYTOPLASMIC TAIL; ENERGY PRODUCTIONS; HYPOXIA-INDUCIBLE FACTOR 1; INNATE IMMUNE SYSTEMS; MEMBRANE PROTEASE; MEMBRANE TYPE-1 MATRIX METALLOPROTEINASE; OXIDATIVE PHOSPHORYLATION; PROTEOLYTIC MECHANISMS; SUPPORT ENERGY; WILD-TYPE CELLS;

MACROPHAGES;

ADENOSINE TRIPHOSPHATE; GENE PRODUCT; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1; MATRIX METALLOPROTEINASE 14; PHOSPHOGLYCERATE KINASE; PHOSPHOGLYCERATE KINASE 1; PROTEIN MINT3; UNCLASSIFIED DRUG; APBA3 PROTEIN, HUMAN; APBA3 PROTEIN, MOUSE; CARRIER PROTEIN; FACTOR INHIBITING HYPOXIA-INDUCIBLE FACTOR 1, MOUSE; HIF1AN PROTEIN, HUMAN; MIXED FUNCTION OXIDASE; MMP14 PROTEIN, HUMAN; MMP14 PROTEIN, MOUSE; PROTEIN; REPRESSOR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL ENERGY; CELL HYPOXIA; CELL MUTANT; CONTROLLED STUDY; DELETION MUTANT; GENE EXPRESSION; GLYCOLYSIS; GOLGI COMPLEX; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; WILD TYPE; ANIMAL; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; ANIMALS; CARRIER PROTEINS; CELL LINE; GENE EXPRESSION REGULATION; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MACROPHAGES; MATRIX METALLOPROTEINASE 14; MICE; MICE, KNOCKOUT; MIXED FUNCTION OXYGENASES; PROTEINS; REPRESSOR PROTEINS;

EID: 77956910491     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.132704     Document Type: Article

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