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Volumn 10, Issue 8, 2010, Pages 594-604

The X chromosome in immune functions: When a chromosome makes the difference

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; SEX HORMONE;

EID: 77954948753     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri2815     Document Type: Review
Times cited : (547)

References (102)
  • 1
    • 0034578448 scopus 로고    scopus 로고
    • Longevity and the immune response
    • Aspinall, R. Longevity and the immune response. Biogerontology 1, 273-278 (2000).
    • (2000) Biogerontology , vol.1 , pp. 273-278
    • Aspinall, R.1
  • 3
    • 5444260748 scopus 로고    scopus 로고
    • Male gender is associated with increased risk for postinjury pneumonia
    • Gannon, C. J., Pasquale, M., Tracy, J. K., McCarter, R. J. & Napolitano, L. M. Male gender is associated with increased risk for postinjury pneumonia. Shock 21, 410-414 (2004).
    • (2004) Shock , vol.21 , pp. 410-414
    • Gannon, C.J.1    Pasquale, M.2    Tracy, J.K.3    McCarter, R.J.4    Napolitano, L.M.5
  • 4
    • 0014209455 scopus 로고
    • Influence of sex on immunoglobulin levels
    • Butterworth, M., McClellan, B. & Aklansmith, M. Influence of sex on immunoglobulin levels. Nature 214, 1224-1225 (1967).
    • (1967) Nature , vol.214 , pp. 1224-1225
    • Butterworth, M.1    McClellan, B.2    Aklansmith, M.3
  • 5
    • 0018582511 scopus 로고
    • Immunological bases for superior survival of females
    • Purtilo, D. T. & Sullivan, J. L. Immunological bases for superior survival of females. Am. J. Dis. Child. 133, 1251-1253 (1979).
    • (1979) Am. J. Dis. Child. , vol.133 , pp. 1251-1253
    • Purtilo, D.T.1    Sullivan, J.L.2
  • 6
    • 54949099750 scopus 로고
    • Genetic origin of some sex differences among human beings
    • Burch, P. R. J. & Rowell, N. R. Genetic origin of some sex differences among human beings. Pediatrics 36, 658-659 (1965).
    • (1965) Pediatrics , vol.36 , pp. 658-659
    • Burch, P.R.J.1    Rowell, N.R.2
  • 8
    • 0015024120 scopus 로고
    • Epidemiologic patterns of acute lower respiratory disease of children in a pediatric group practice
    • Glezen, W. P. et al. Epidemiologic patterns of acute lower respiratory disease of children in a pediatric group practice. J. Pediatr. 78, 397-406 (1971).
    • (1971) J. Pediatr. , vol.78 , pp. 397-406
    • Glezen, W.P.1
  • 10
    • 84941815810 scopus 로고
    • Antibody distribution against non-enteropathic e
    • Kunin, C. M. Antibody distribution against non-enteropathic E. coli. Arch. Intern. Med. 110, 676-686 (1962).
    • (1962) Coli. Arch. Intern. Med. , vol.110 , pp. 676-686
    • Kunin, C.M.1
  • 12
    • 54049091198 scopus 로고    scopus 로고
    • Sexual dimorphism in campylobacteriosis
    • Strachan, N. J. C. et al. Sexual dimorphism in campylobacteriosis. Epidemiol. Infect. 136, 1492-1495 (2008).
    • (2008) Epidemiol. Infect. , vol.136 , pp. 1492-1495
    • Strachan, N.J.C.1
  • 13
    • 0026516432 scopus 로고
    • The male predominance in the incidence of infectious diseases in children: A postulated explanation for disparities in the literature
    • Green, M. S. The male predominance in the incidence of infectious diseases in children: a postulated explanation for disparities in the literature. Int. J. Epidemiol. 21, 381-386 (1992).
    • (1992) Int. J. Epidemiol. , vol.21 , pp. 381-386
    • Green, M.S.1
  • 14
    • 77954361177 scopus 로고    scopus 로고
    • The evolution of sex-specific immune defenses
    • doi:10.1098/rspb.2010.0188
    • Restif, O. & William, A. The evolution of sex-specific immune defenses. Proc. R. Soc. Lond. B Biol. Sci. Mar 24 2010 (doi:10.1098/rspb.2010. 0188).
    • (2010) Proc. R. Soc. Lond. B Biol. Sci. Mar , vol.24
    • Restif, O.1    William, A.2
  • 15
    • 33645082502 scopus 로고    scopus 로고
    • The role of X inactivation and cellular mosaicism in women's health and sex-specific diseases
    • Migeon, B. R. The role of X inactivation and cellular mosaicism in women's health and sex-specific diseases. JAMA 295, 1428-1433 (2006).
    • (2006) JAMA , vol.295 , pp. 1428-1433
    • Migeon, B.R.1
  • 16
    • 59249085223 scopus 로고    scopus 로고
    • Hypothesis: Increased male mortality caused by infection is due to a decrease in heterozygous loci as a result of a single X chromosome
    • Morris, J. A. & Harrison, L. M. Hypothesis: increased male mortality caused by infection is due to a decrease in heterozygous loci as a result of a single X chromosome. Med. Hypotheses 72, 322-324 (2009).
    • (2009) Med. Hypotheses , vol.72 , pp. 322-324
    • Morris, J.A.1    Harrison, L.M.2
  • 17
    • 34249033728 scopus 로고    scopus 로고
    • The X-files of inflammation: Cellular mosaicism of X-linked polymorphic genes and the female advantage in the host response to injury and infection
    • Spolarics, Z. The X-files of inflammation: cellular mosaicism of X-linked polymorphic genes and the female advantage in the host response to injury and infection. Shock 27, 597-604 (2007).
    • (2007) Shock , vol.27 , pp. 597-604
    • Spolarics, Z.1
  • 18
    • 4344685681 scopus 로고    scopus 로고
    • Sex chromosomes and brain gender
    • Arnold, A. P. Sex chromosomes and brain gender. Nature Rev. Neurosci. 5, 701-708 (2004).
    • (2004) Nature Rev. Neurosci. , vol.5 , pp. 701-708
    • Arnold, A.P.1
  • 20
    • 49349084347 scopus 로고    scopus 로고
    • X chromosome inactivation and female predisposition to autoimmunity
    • Ozcelik, T. X chromosome inactivation and female predisposition to autoimmunity. Clin. Rev. Allergy Immunol. 34, 348-351 (2008).
    • (2008) Clin. Rev. Allergy Immunol. , vol.34 , pp. 348-351
    • Ozcelik, T.1
  • 21
    • 56349118441 scopus 로고    scopus 로고
    • The X in sex: How autoimmune diseases revolve around sex chromosomes
    • Selmi, C. The X in sex: how autoimmune diseases revolve around sex chromosomes. Best Pract. Res. Clin. Rheumatol. 22, 913-922 (2008).
    • (2008) Best Pract. Res. Clin. Rheumatol. , vol.22 , pp. 913-922
    • Selmi, C.1
  • 22
    • 33748435645 scopus 로고    scopus 로고
    • Neutrophil activation is modulated by sex hormones after trauma-hemorrhagic shock and burn injuries
    • Deitch, E. A. et al. Neutrophil activation is modulated by sex hormones after trauma-hemorrhagic shock and burn injuries. Am. J. Physiol. Heart Circ. Physiol. 291, 1456-1465 (2006).
    • (2006) Am. J. Physiol. Heart Circ. Physiol. , vol.291 , pp. 1456-1465
    • Deitch, E.A.1
  • 23
    • 18244373936 scopus 로고    scopus 로고
    • Understanding sex biases in immunity\effects of estrogen on the differentiation and function of antigen-presenting cells
    • Nalbandian, G. & Kovats, S. Understanding sex biases in immunity\effects of estrogen on the differentiation and function of antigen-presenting cells. Immunol. Res. 31, 91-106 (2005).
    • (2005) Immunol. Res. , vol.31 , pp. 91-106
    • Nalbandian, G.1    Kovats, S.2
  • 24
    • 33745795993 scopus 로고    scopus 로고
    • Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis
    • Szalay, L. et al. Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis. Am. J. Physiol. Gastrointest. Liver Physiol. 291, 260-266 (2006).
    • (2006) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.291 , pp. 260-266
    • Szalay, L.1
  • 25
    • 0029654179 scopus 로고
    • The genetic basis of XX-XY differences present before gonadal sex differentiation in the mouse
    • Burgoyne, P. S. et al. The genetic basis of XX-XY differences present before gonadal sex differentiation in the mouse. Philos. Trans. R. Soc. Lond. B Biol. Sci. 350, 253-260 (1995).
    • (1995) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.350 , pp. 253-260
    • Burgoyne, P.S.1
  • 26
    • 23044443979 scopus 로고    scopus 로고
    • A Yin-Yang effect between sex chromosome complement and sex hormones on the immune response
    • Palaszynski, K. M. et al. A Yin-Yang effect between sex chromosome complement and sex hormones on the immune response. Endocrinology 146, 3280-3285 (2005).
    • (2005) Endocrinology , vol.146 , pp. 3280-3285
    • Palaszynski, K.M.1
  • 27
    • 0002437146 scopus 로고
    • Sex differences in susceptibility to infections
    • Washburn, T. C., Medearis, D. N. & Childs, B. Sex differences in susceptibility to infections. Pediatrics 35, 57-64 (1965).
    • (1965) Pediatrics , vol.35 , pp. 57-64
    • Washburn, T.C.1    Medearis, D.N.2    Childs, B.3
  • 28
    • 0018760137 scopus 로고
    • Differential mortality by sex in fetal and neonatal deaths
    • McMillen, M. M. Differential mortality by sex in fetal and neonatal deaths. Science 204, 89-91 (1979).
    • (1979) Science , vol.204 , pp. 89-91
    • McMillen, M.M.1
  • 30
    • 0031081705 scopus 로고    scopus 로고
    • A genetic basis for the sudden infant death syndrome sex ratio
    • Mage, D. T. & Donner, M. A genetic basis for the sudden infant death syndrome sex ratio. Med. Hypotheses 48, 137-142 (1997).
    • (1997) Med. Hypotheses , vol.48 , pp. 137-142
    • Mage, D.T.1    Donner, M.2
  • 31
    • 44349158293 scopus 로고    scopus 로고
    • Sudden unexpected death in infancy: Evidence of infection
    • Morris, J. A. & Harrison, L. M. Sudden unexpected death in infancy: evidence of infection. Lancet 371, 1815-1816 (2008).
    • (2008) Lancet , vol.371 , pp. 1815-1816
    • Morris, J.A.1    Harrison, L.M.2
  • 32
    • 44349181395 scopus 로고    scopus 로고
    • Infection and sudden unexpected death in infancy: A systematic retrospective case review
    • Weber, M. A. et al. Infection and sudden unexpected death in infancy: a systematic retrospective case review. Lancet 371, 1848-1853 (2008).
    • (2008) Lancet , vol.371 , pp. 1848-1853
    • Weber, M.A.1
  • 33
    • 33646062006 scopus 로고    scopus 로고
    • Primary immunodeficiency diseases: An update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee meeting in Budapest 2005
    • Notarangelo, L. et al. Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee meeting in Budapest, 2005. J. Allergy Clin. Immunol. 117, 883-896 (2006).
    • (2006) J. Allergy Clin. Immunol. , vol.117 , pp. 883-896
    • Notarangelo, L.1
  • 34
    • 67349248095 scopus 로고    scopus 로고
    • X-linked primary immunodeficiencies as a bridge to better understanding X-chromosome related autoimmunity
    • Pessach, I. M. & Notarangelo, L. D. X-linked primary immunodeficiencies as a bridge to better understanding X-chromosome related autoimmunity. J. Autoimmun. 33, 17-24 (2009).
    • (2009) J. Autoimmun. , vol.33 , pp. 17-24
    • Pessach, I.M.1    Notarangelo, L.D.2
  • 35
    • 0023191301 scopus 로고
    • The X-linked chronic granulomatous-disease gene codes for the β-chain of cytochrome-b-245
    • Teahan, C., Rowe, P., Parker, P., Totty, N. & Segal, A. W. The X-linked chronic granulomatous-disease gene codes for the β-chain of cytochrome-b-245. Nature 327, 720-721 (1987).
    • (1987) Nature , vol.327 , pp. 720-721
    • Teahan, C.1    Rowe, P.2    Parker, P.3    Totty, N.4    Segal, A.W.5
  • 36
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • Bennett, C. et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nature Genet. 27, 20-21 (2001).
    • (2001) Nature Genet. , vol.27 , pp. 20-21
    • Bennett, C.1
  • 37
    • 0027403374 scopus 로고
    • Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans
    • Noguchi, M. et al. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 73, 147-157 (1993)
    • (1993) Cell , vol.73 , pp. 147-157
    • Noguchi, M.1
  • 38
    • 0035752146 scopus 로고    scopus 로고
    • Cytokines and immunodeficiency diseases
    • Leonard, W. J. Cytokines and immunodeficiency diseases. Nature Rev. Immunol. 1, 200-208 (2001).
    • (2001) Nature Rev. Immunol. , vol.1 , pp. 200-208
    • Leonard, W.J.1
  • 39
    • 0031795459 scopus 로고    scopus 로고
    • Neutrophils and monocytes from subjects with the Mediterranean G6PD variant: Effect of Plasmodium falciparum hemozoin on G6PD activity, oxidative burst and cytokine production
    • Mordmuller, B., Turrini, F., Long, H., Kremsner, P. G. & Arese, P. Neutrophils and monocytes from subjects with the Mediterranean G6PD variant: effect of Plasmodium falciparum hemozoin on G6PD activity, oxidative burst and cytokine production. Eur. Cytokine Netw. 9, 239-245 (1998).
    • (1998) Eur. Cytokine Netw. , vol.9 , pp. 239-245
    • Mordmuller, B.1    Turrini, F.2    Long, H.3    Kremsner, P.G.4    Arese, P.5
  • 40
    • 22144487340 scopus 로고    scopus 로고
    • Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages
    • Wilmanski, J., Siddiqi, M., Deitch, E. A. & Spolarics, Z. Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages. J. Leukoc. Biol. 78, 85-94 (2005).
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 85-94
    • Wilmanski, J.1    Siddiqi, M.2    Deitch, E.A.3    Spolarics, Z.4
  • 41
    • 0034713270 scopus 로고    scopus 로고
    • Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti
    • The International Incontinentia Pigmenti (IP) Consortium
    • Smahi, A. et al. Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature 405, 466-472 (2000).
    • (2000) Nature , vol.405 , pp. 466-472
    • Smahi, A.1
  • 42
    • 27944501076 scopus 로고    scopus 로고
    • The range of defects associated with nuclear factor κb essential modulator
    • Uzel, G. The range of defects associated with nuclear factor κB essential modulator. Curr. Opin. Allergy Clin. Immunol. 5, 513-518 (2005).
    • (2005) Curr. Opin. Allergy Clin. Immunol. , vol.5 , pp. 513-518
    • Uzel, G.1
  • 43
    • 1942500166 scopus 로고    scopus 로고
    • The presentation and natural history of immunodeficiency caused by nuclear factor κb essential modulator mutation
    • Orange, J. S. et al. The presentation and natural history of immunodeficiency caused by nuclear factor κB essential modulator mutation. J. Allergy Clin. Immunol. 11 3, 725-733 (2004).
    • (2004) J. Allergy Clin. Immunol. , vol.113 , pp. 725-733
    • Orange, J.S.1
  • 44
    • 4444279550 scopus 로고    scopus 로고
    • Human nuclear factor κb essential modulator mutation can result in immunodeficiency without ectodermal dysplasia
    • Orange, J. S. et al. Human nuclear factor κB essential modulator mutation can result in immunodeficiency without ectodermal dysplasia. J. Allergy Clin. Immunol. 11 4, 650-656 (2004).
    • (2004) J. Allergy Clin. Immunol. , vol.114 , pp. 650-656
    • Orange, J.S.1
  • 45
    • 13144261692 scopus 로고    scopus 로고
    • Human disease resulting from gene mutations that interfere with appropriate nuclear factor-κB activation
    • Orange, J. S., Levy, O. & Geha, R. S. Human disease resulting from gene mutations that interfere with appropriate nuclear factor-κB activation. Immunol. R e v. 203, 21-37 (2005).
    • (2005) Immunol. R e V. , vol.203 , pp. 21-37
    • Orange, J.S.1    Levy, O.2    Geha, R.S.3
  • 46
    • 33746218184 scopus 로고    scopus 로고
    • Evolution on the X chromosome: Unusual patterns and processes
    • Vicoso, B. & Charlesworth, B. Evolution on the X chromosome: unusual patterns and processes. Nature Rev. Gen. 7, 645-653 (2006).
    • (2006) Nature Rev. Gen. , vol.7 , pp. 645-653
    • Vicoso, B.1    Charlesworth, B.2
  • 48
    • 29444455049 scopus 로고    scopus 로고
    • Dosage compensation of the active X chromosome in mammals
    • Nguyen, D. K. & Disteche, C. M. Dosage compensation of the active X chromosome in mammals. Nature Genet. 38, 47-53 (2006).
    • (2006) Nature Genet. , vol.38 , pp. 47-53
    • Nguyen, D.K.1    Disteche, C.M.2
  • 49
    • 1042279660 scopus 로고    scopus 로고
    • How mammalian sex chromosomes acquired their peculiar gene content
    • Vallender, E. J. & Lahn, B. T. How mammalian sex chromosomes acquired their peculiar gene content. Bioessays 26, 159-169 (2004).
    • (2004) Bioessays , vol.26 , pp. 159-169
    • Vallender, E.J.1    Lahn, B.T.2
  • 50
    • 0035071815 scopus 로고    scopus 로고
    • An abundance of X-linked genes expressed in spermatogonia
    • Wang, P. J., McCarrey, J. R., Yang, F. & Page, D. C. An abundance of X-linked genes expressed in spermatogonia. Nature Genet. 27, 422-426 (2001).
    • (2001) Nature Genet. , vol.27 , pp. 422-426
    • Wang, P.J.1    McCarrey, J.R.2    Yang, F.3    Page, D.C.4
  • 51
    • 15244363491 scopus 로고    scopus 로고
    • The DNA sequence of the human X chromosome
    • Ross, M. T. et al. The DNA sequence of the human X chromosome. Nature 434, 325-337 (2005).
    • (2005) Nature , vol.434 , pp. 325-337
    • Ross, M.T.1
  • 52
    • 15244353967 scopus 로고    scopus 로고
    • X-inactivation profile reveals extensive variability in X-linked gene expression in females
    • Carrel, L. & Willard, H. F. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434, 400-404 (2005).
    • (2005) Nature , vol.434 , pp. 400-404
    • Carrel, L.1    Willard, H.F.2
  • 53
    • 38949090440 scopus 로고    scopus 로고
    • Large-scale population study of human cell lines indicates that dosage compensation is virtually complete
    • Johnston, C. M. et al. Large-scale population study of human cell lines indicates that dosage compensation is virtually complete. Plos Genet. 4, e9 (2008).
    • (2008) Plos Genet. , vol.4
    • Johnston, C.M.1
  • 54
    • 68249102048 scopus 로고    scopus 로고
    • Evolution and survival on eutherian sex chromosomes
    • Wilson, M. A. & Makova, K. D. Evolution and survival on eutherian sex chromosomes. PLoS Genet. 5, e1000568 (2009).
    • (2009) PLoS Genet. , vol.5
    • Wilson, M.A.1    Makova, K.D.2
  • 55
    • 5444256749 scopus 로고    scopus 로고
    • The AZFa gene DBY (DDX3Y) is widely transcribed but the protein is limited to the male germ cells by translation control
    • Ditton, H. J., Zimmer, J., Rajpert-De Meyts, E. & Vogt, P. H. The AZFa gene DBY (DDX3Y) is widely transcribed but the protein is limited to the male germ cells by translation control. Hum. Mol. Genet. 13, 2333-2341 (2004).
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 2333-2341
    • Ditton, H.J.1    Zimmer, J.2    Rajpert-De Meyts, E.3    Vogt, P.H.4
  • 56
    • 84925566754 scopus 로고    scopus 로고
    • The TBK-1 substrate DDX3X, a DEAD-box RNA helicase, provides innate immunity to Listeria monocytogenes
    • Decker, T. et al. The TBK-1 substrate DDX3X, a DEAD-box RNA helicase, provides innate immunity to Listeria monocytogenes. Cytokine 43, 304 (2008).
    • (2008) Cytokine , vol.43 , pp. 304
    • Decker, T.1
  • 57
    • 49149114140 scopus 로고    scopus 로고
    • The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response
    • Soulat, D. et al. The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response. EMBO J. 27, 2135-2146 (2008).
    • (2008) EMBO J. , vol.27 , pp. 2135-2146
    • Soulat, D.1
  • 58
    • 0033358525 scopus 로고    scopus 로고
    • Polymorphic X-chromosome inactivation of the human TIMP1 gene
    • Anderson, C. L. & Brown, C. J. Polymorphic X-chromosome inactivation of the human TIMP1 gene. Am. J. Hum. Genet. 65, 699-708 (1999).
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 699-708
    • Anderson, C.L.1    Brown, C.J.2
  • 59
    • 0030952221 scopus 로고    scopus 로고
    • Expression of genes from the human active and inactive X chromosomes
    • Brown, C. J., Carrel, L. & Willard, H. F. Expression of genes from the human active and inactive X chromosomes. Am. J. Hum. Genet. 60, 1333-1343 (1997).
    • (1997) Am. J. Hum. Genet. , vol.60 , pp. 1333-1343
    • Brown, C.J.1    Carrel, L.2    Willard, H.F.3
  • 60
    • 66449132072 scopus 로고    scopus 로고
    • Matrix metalloproteinases as drug targets in infections caused by Gram-negative bacteria and in septic shock
    • Vanlaere, I. & Libert, C. Matrix metalloproteinases as drug targets in infections caused by Gram-negative bacteria and in septic shock. Clin. Microbiol. Rev. 22, 224-239 (2009).
    • (2009) Clin. Microbiol. Rev. , vol.22 , pp. 224-239
    • Vanlaere, I.1    Libert, C.2
  • 61
    • 33749354927 scopus 로고    scopus 로고
    • Matrix-metalloproteinases and their inhibitors are elevated in severe sepsis: Prognostic value of TIMP-1 in severe sepsis
    • Hoffmann, U. et al. Matrix-metalloproteinases and their inhibitors are elevated in severe sepsis: prognostic value of TIMP-1 in severe sepsis. Scand. J. Infect. Dis. 38, 867-872 (2006).
    • (2006) Scand. J. Infect. Dis. , vol.38 , pp. 867-872
    • Hoffmann, U.1
  • 62
    • 70450177659 scopus 로고    scopus 로고
    • Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis
    • Burkhardt, J. et al. Association of the X-chromosomal genes TIMP1 and IL9R with rheumatoid arthritis. J. Rheumatol. 36, 2149-2157 (2009).
    • (2009) J. Rheumatol. , vol.36 , pp. 2149-2157
    • Burkhardt, J.1
  • 63
    • 34547842802 scopus 로고    scopus 로고
    • Why females are mosaics, X-chromosome inactivation, and sex differences in disease
    • Migeon, B. R. Why females are mosaics, X-chromosome inactivation, and sex differences in disease. Gend. Med. 4, 97-105 (2007).
    • (2007) Gend. Med. , vol.4 , pp. 97-105
    • Migeon, B.R.1
  • 64
    • 0031821968 scopus 로고    scopus 로고
    • Non-random X chromosome inactivation in mammalian cells
    • Migeon, B. R. Non-random X chromosome inactivation in mammalian cells. Cytogenet. Cell Genet. 80, 142-148 (1998).
    • (1998) Cytogenet. Cell Genet. , vol.80 , pp. 142-148
    • Migeon, B.R.1
  • 65
    • 70349314767 scopus 로고    scopus 로고
    • X chromosome inactivation in clinical practice
    • Orstavik, K. H. X chromosome inactivation in clinical practice. Hum. Genet. 126, 363-373 (2009).
    • (2009) Hum. Genet. , vol.126 , pp. 363-373
    • Orstavik, K.H.1
  • 66
    • 0024571506 scopus 로고
    • Selection against lethal alleles in females heterozygous for incontinentia pigmenti
    • Migeon, B. R. et al. Selection against lethal alleles in females heterozygous for incontinentia pigmenti. Am. J. Hum. Genet. 44, 100-106 (1989).
    • (1989) Am. J. Hum. Genet. , vol.44 , pp. 100-106
    • Migeon, B.R.1
  • 68
    • 0033939292 scopus 로고    scopus 로고
    • Molecular characterisation of 10 Dutch properdin type i deficient families: Mutation analysis and X-inactivation studies
    • Van den Bogaard, R. et al. Molecular characterisation of 10 Dutch properdin type I deficient families: mutation analysis and X-inactivation studies. Eur. J. Hum. Genet. 8, 513-518 (2000).
    • (2000) Eur. J. Hum. Genet. , vol.8 , pp. 513-518
    • Van Den Bogaard, R.1
  • 69
    • 33847083891 scopus 로고    scopus 로고
    • Gender as risk factor for autoimmune diseases
    • Gleicher, N. & Barad, D. H. Gender as risk factor for autoimmune diseases. J. Autoimmun. 28, 1-6 (2007).
    • (2007) J. Autoimmun. , vol.28 , pp. 1-6
    • Gleicher, N.1    Barad, D.H.2
  • 70
    • 0031240055 scopus 로고    scopus 로고
    • Epidemiology and estimated population burden of selected autoimmune diseases in the United States
    • Jacobson, D. L., Gange, S. J., Rose, N. R. & Graham, N. M. H. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin. Immunol. Immunopathol. 84, 223-243 (1997).
    • (1997) Clin. Immunol. Immunopathol. , vol.84 , pp. 223-243
    • Jacobson, D.L.1    Gange, S.J.2    Rose, N.R.3    Graham, N.M.H.4
  • 71
    • 0017536728 scopus 로고
    • Hypothesis-predominance of autoimmune and rheumatic diseases in females
    • Kast, R. E. Hypothesis-predominance of autoimmune and rheumatic diseases in females. J. Rheumatol. 4, 288-292 (1977).
    • (1977) J. Rheumatol. , vol.4 , pp. 288-292
    • Kast, R.E.1
  • 72
    • 0031839419 scopus 로고    scopus 로고
    • The female X-inactivation mosaic in systemic lupus erythematosus
    • Stewart, J. J. The female X-inactivation mosaic in systemic lupus erythematosus. Immunol. Today 19, 352-357 (1998).
    • (1998) Immunol. Today , vol.19 , pp. 352-357
    • Stewart, J.J.1
  • 73
    • 0031112357 scopus 로고    scopus 로고
    • Autoreactive T cell clones from patients with systemic lupus erythematosus support polyclonal autoantibody production
    • Takeno, M. et al. Autoreactive T cell clones from patients with systemic lupus erythematosus support polyclonal autoantibody production. J. Immunol. 158, 3529-3538 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 3529-3538
    • Takeno, M.1
  • 74
    • 49449099801 scopus 로고    scopus 로고
    • Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: Support for the notion of a gene-dose effect from the X chromosome
    • Scofield, R. H. et al. Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome. Arthritis Rheum. 58, 2511-2517 (2008).
    • (2008) Arthritis Rheum. , vol.58 , pp. 2511-2517
    • Scofield, R.H.1
  • 75
    • 0035152359 scopus 로고    scopus 로고
    • Evidence of skewed X-chromosome inactivation in 47,XXY and 48,XXYY Klinefelter patients
    • Litsuka, Y. et al. Evidence of skewed X-chromosome inactivation in 47,XXY and 48,XXYY Klinefelter patients. Am. J. Med. Genet. 98, 25-31 (2001).
    • (2001) Am. J. Med. Genet. , vol.98 , pp. 25-31
    • Litsuka, Y.1
  • 76
    • 27744454481 scopus 로고    scopus 로고
    • High frequency of skewed X-chromosome inactivation in females with autoimmune thyroid disease: A possible explanation for the female predisposition to thyroid autoimmunity
    • Brix, T. H. et al. High frequency of skewed X-chromosome inactivation in females with autoimmune thyroid disease: A possible explanation for the female predisposition to thyroid autoimmunity. J. Clin. Endocrinol. Metab. 90, 5949-5953 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 5949-5953
    • Brix, T.H.1
  • 77
    • 18544413131 scopus 로고    scopus 로고
    • Skewed X chromosome inactivation in blood cells of women with scleroderma
    • Ozbalkan, Z. et al. Skewed X chromosome inactivation in blood cells of women with scleroderma. Arthritis Rheum. 52, 1564-1570 (2005).
    • (2005) Arthritis Rheum. , vol.52 , pp. 1564-1570
    • Ozbalkan, Z.1
  • 78
    • 33744503390 scopus 로고    scopus 로고
    • Evidence from autoimmune thyroiditis of skewed X-chromosome inactivation in female predisposition to autoimmunity
    • Ozcelik, T. et al. Evidence from autoimmune thyroiditis of skewed X-chromosome inactivation in female predisposition to autoimmunity. Eur. J. Hum. Genet. 14, 791-797 (2006).
    • (2006) Eur. J. Hum. Genet. , vol.14 , pp. 791-797
    • Ozcelik, T.1
  • 79
    • 49349096392 scopus 로고    scopus 로고
    • Skewed X-chromosome inactivation in scleroderma
    • Uz, E. et al. Skewed X-chromosome inactivation in scleroderma. Clin. Rev. Allergy Immunol. 34, 352-355 (2008).
    • (2008) Clin. Rev. Allergy Immunol. , vol.34 , pp. 352-355
    • Uz, E.1
  • 80
    • 35748975958 scopus 로고    scopus 로고
    • The X chromosome in female-predominant autoimmune diseases
    • Invernizzi, P. The X chromosome in female-predominant autoimmune diseases. Ann. N Y Acad. Sci. 1110, 57-64 (2007).
    • (2007) Ann. N y Acad. Sci. , vol.1110 , pp. 57-64
    • Invernizzi, P.1
  • 81
    • 0034468292 scopus 로고    scopus 로고
    • The role of X-chromosome inactivation in female predisposition to autoimmunity
    • Chitnis, S. et al. The role of X-chromosome inactivation in female predisposition to autoimmunity. Arthritis Res. 2, 399-406 (2000).
    • (2000) Arthritis Res. , vol.2 , pp. 399-406
    • Chitnis, S.1
  • 82
    • 38449116161 scopus 로고    scopus 로고
    • Demethylation of CD40LG on the inactive X in T cells from women with lupus
    • Lu, Q. et al. Demethylation of CD40LG on the inactive X in T cells from women with lupus. J. Immunol. 179, 6352-6358 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 6352-6358
    • Lu, Q.1
  • 83
    • 70349745364 scopus 로고    scopus 로고
    • X chromosome reactivation perturbs intracellular self/not-self discrimination
    • Forsdyke, D. R. X chromosome reactivation perturbs intracellular self/not-self discrimination. Immunol. Cell Biol. 87, 525-528 (2009).
    • (2009) Immunol. Cell Biol. , vol.87 , pp. 525-528
    • Forsdyke, D.R.1
  • 84
    • 67651152585 scopus 로고    scopus 로고
    • T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus
    • Zhou, Y. et al. T cell CD40LG gene expression and the production of IgG by autologous B cells in systemic lupus erythematosus. Clin. Immunol. 132, 362-370 (2009).
    • (2009) Clin. Immunol. , vol.132 , pp. 362-370
    • Zhou, Y.1
  • 85
    • 33745617886 scopus 로고    scopus 로고
    • A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
    • Subramanian, S. et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc. Natl Acad. Sci. USA 103, 9970-9975 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 9970-9975
    • Subramanian, S.1
  • 86
    • 43549091132 scopus 로고    scopus 로고
    • A role for sex chromosome complement in the female bias in autoimmune disease
    • Smith-Bouvier, D. L. et al. A role for sex chromosome complement in the female bias in autoimmune disease. J. Exp. Med. 205, 1099-1108 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 1099-1108
    • Smith-Bouvier, D.L.1
  • 87
    • 21244456843 scopus 로고    scopus 로고
    • X chromosome monosomy: A common mechanism for autoimmune diseases
    • Invernizzi, P. et al. X chromosome monosomy: a common mechanism for autoimmune diseases. J. Immunol. 175, 575-578 (2005).
    • (2005) J. Immunol. , vol.175 , pp. 575-578
    • Invernizzi, P.1
  • 88
    • 0035963921 scopus 로고    scopus 로고
    • Turner's syndrome
    • Ranke, M. B. & Saenger, P. Turner's syndrome. Lancet 358, 309-314 (2001).
    • (2001) Lancet , vol.358 , pp. 309-314
    • Ranke, M.B.1    Saenger, P.2
  • 89
    • 0034825344 scopus 로고    scopus 로고
    • Autoimmune thyroid syndrome in women with Turner's syndrome\the association with karyotype
    • Elsheikh, M., Wass, J. A. H. & Conway, G. S. Autoimmune thyroid syndrome in women with Turner's syndrome\the association with karyotype. Clin. Endocrinol. 55, 223-226 (2001).
    • (2001) Clin. Endocrinol. , vol.55 , pp. 223-226
    • Elsheikh, M.1    Wass, J.A.H.2    Conway, G.S.3
  • 91
    • 70349667487 scopus 로고    scopus 로고
    • Monosomy for the X chromosome
    • Bondy, C. A. & Cheng, C. Monosomy for the X chromosome. Chromosome Res. 17, 649-658 (2009).
    • (2009) Chromosome Res. , vol.17 , pp. 649-658
    • Bondy, C.A.1    Cheng, C.2
  • 93
    • 0035865397 scopus 로고    scopus 로고
    • Our genome unveiled
    • Baltimore, D. Our genome unveiled. Nature 409, 814-816 (2001).
    • (2001) Nature , vol.409 , pp. 814-816
    • Baltimore, D.1
  • 94
    • 0033460319 scopus 로고    scopus 로고
    • Escapees on the X chromosome
    • Disteche, C. M. Escapees on the X chromosome. Proc. Natl Acad. Sci. USA 96, 14180-14182 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 14180-14182
    • Disteche, C.M.1
  • 96
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B. P., Burge, C. B. & Bartel, D. P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (2005).
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 97
    • 63049087072 scopus 로고    scopus 로고
    • Rapid evolution of mammalian X-linked testis microRNAs
    • Guo, X. J., Su, B., Zhou, Z. M. & Sha, J. H. Rapid evolution of mammalian X-linked testis microRNAs. BMC Genomics 10, 97(2009).
    • (2009) BMC Genomics , vol.10 , pp. 97
    • Guo, X.J.1    Su, B.2    Zhou, Z.M.3    Sha, J.H.4
  • 98
    • 34547791273 scopus 로고    scopus 로고
    • Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation
    • le Sage, C. et al. Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation. EMBO J. 26, 3699-3708 (2007).
    • (2007) EMBO J. , vol.26 , pp. 3699-3708
    • Le Sage, C.1
  • 99
    • 39849096995 scopus 로고    scopus 로고
    • Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
    • Johnnidis, J. B. et al. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 451, 1125-1129 (2008).
    • (2008) Nature , vol.451 , pp. 1125-1129
    • Johnnidis, J.B.1
  • 100
    • 34347383305 scopus 로고    scopus 로고
    • MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation
    • Fontana, L. et al. MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation. Nature Cell Biol. 9, 775-787 (2007).
    • (2007) Nature Cell Biol. , vol.9 , pp. 775-787
    • Fontana, L.1
  • 101
    • 38049146022 scopus 로고    scopus 로고
    • The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation
    • Rosa, A. et al. The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. Proc. Natl Acad. Sci. USA 104, 19849-19854 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 19849-19854
    • Rosa, A.1
  • 102
    • 0141819043 scopus 로고    scopus 로고
    • The epidemiology of autoimmune diseases
    • Cooper, G. S. & Stroehla, B. C. The epidemiology of autoimmune diseases. Autoimmun. Rev. 2, 119-125 (2003).
    • (2003) Autoimmun. Rev. , vol.2 , pp. 119-125
    • Cooper, G.S.1    Stroehla, B.C.2


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