메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; VACCINE;

EID: 85002604782     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep38666     Document Type: Article
Times cited : (6)

References (58)
  • 2
    • 0035858127 scopus 로고    scopus 로고
    • Neonatal and early life vaccinology
    • Siegrist, C. A. Neonatal and early life vaccinology. Vaccine 19, 3331-3346 (2001).
    • (2001) Vaccine , vol.19 , pp. 3331-3346
    • Siegrist, C.A.1
  • 3
    • 47549116006 scopus 로고    scopus 로고
    • Vaccines: Correlates of vaccine-induced immunity
    • Plotkin, S. A. Vaccines: correlates of vaccine-induced immunity. Clin. Infect. Dis. 47, 401-409 (2008).
    • (2008) Clin. Infect. Dis. , vol.47 , pp. 401-409
    • Plotkin, S.A.1
  • 4
    • 0034728671 scopus 로고    scopus 로고
    • A new theory of cytotoxic T-lymphocyte memory: Implications for HIV treatment
    • Wodarz, D. et al. A new theory of cytotoxic T-lymphocyte memory: implications for HIV treatment. Philos. Trans. R. Soc. Lond B Biol. Sci. 355, 329-343 (2000).
    • (2000) Philos. Trans. R. Soc. Lond B Biol. Sci. , vol.355 , pp. 329-343
    • Wodarz, D.1
  • 5
    • 34447261640 scopus 로고    scopus 로고
    • Protracted course of lymphocytic choriomeningitis virus WE infection in early life: Induction but limited expansion of CD8+ efector T cells and absence of memory CD8+ T cells
    • Belnoue, E., Fontannaz-Bozzotti, P., Grillet, S., Lambert, P. H. & Siegrist, C. A. Protracted course of lymphocytic choriomeningitis virus WE infection in early life: induction but limited expansion of CD8+ efector T cells and absence of memory CD8+ T cells. J. Virol. 81, 7338-7350 (2007).
    • (2007) J. Virol. , vol.81 , pp. 7338-7350
    • Belnoue, E.1    Fontannaz-Bozzotti, P.2    Grillet, S.3    Lambert, P.H.4    Siegrist, C.A.5
  • 6
    • 84884684153 scopus 로고    scopus 로고
    • Acute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses
    • Rudd, B. D. et al. Acute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses. PLoS. Pathog. 9, e1003572 (2013).
    • (2013) PLoS. Pathog. , vol.9 , pp. e1003572
    • Rudd, B.D.1
  • 7
    • 0029902003 scopus 로고    scopus 로고
    • Neonatal and early life immune responses to various forms of vaccine antigens qualitatively difer from adult responses: Predominance of a T2-biased pattern which persists afer adult boosting
    • Barrios, C. et al. Neonatal and early life immune responses to various forms of vaccine antigens qualitatively difer from adult responses: predominance of a T2-biased pattern which persists afer adult boosting. Eur. J. Immunol. 26, 1489-1496 (1996).
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1489-1496
    • Barrios, C.1
  • 8
    • 0022536457 scopus 로고
    • The dual role of lymphocytic choriomeningitis virus-specifc antibodies
    • Tomsen, A. R., Marker, O. & Volkert, M. The dual role of lymphocytic choriomeningitis virus-specifc antibodies. Med. Microbiol. Immunol. 175, 121-124 (1986).
    • (1986) Med. Microbiol. Immunol. , vol.175 , pp. 121-124
    • Tomsen, A.R.1    Marker, O.2    Volkert, M.3
  • 9
    • 0021826471 scopus 로고
    • Diferent isotype profiles of virus-specifc antibodies in acute and persistent lymphocytic choriomeningitis virus infection in mice
    • Tomsen, A. R., Volkert, M. & Marker, O. Diferent isotype profiles of virus-specifc antibodies in acute and persistent lymphocytic choriomeningitis virus infection in mice. Immunology 55, 213-223 (1985).
    • (1985) Immunology , vol.55 , pp. 213-223
    • Tomsen, A.R.1    Volkert, M.2    Marker, O.3
  • 10
    • 0029670540 scopus 로고    scopus 로고
    • Induction of TH1 and TH2 immunity in neonatal mice
    • Forsthuber, T., Yip, H. C. & Lehmann, P. V. Induction of TH1 and TH2 immunity in neonatal mice. Science 271, 1728-1730 (1996).
    • (1996) Science , vol.271 , pp. 1728-1730
    • Forsthuber, T.1    Yip, H.C.2    Lehmann, P.V.3
  • 11
    • 0029991928 scopus 로고    scopus 로고
    • Neonatal tolerance revisited: Turning on newborn T cells with dendritic cells
    • Ridge, J. P., Fuchs, E. J. & Matzinger, P. Neonatal tolerance revisited: turning on newborn T cells with dendritic cells. Science 271, 1723-1726 (1996).
    • (1996) Science , vol.271 , pp. 1723-1726
    • Ridge, J.P.1    Fuchs, E.J.2    Matzinger, P.3
  • 12
    • 0030012251 scopus 로고    scopus 로고
    • Induction of protective CTL responses in newborn mice by a murine retrovirus
    • Sarzotti, M., Robbins, D. S. & Hofman, P. M. Induction of protective CTL responses in newborn mice by a murine retrovirus. Science 271, 1726-1728 (1996).
    • (1996) Science , vol.271 , pp. 1726-1728
    • Sarzotti, M.1    Robbins, D.S.2    Hofman, P.M.3
  • 13
    • 70449629815 scopus 로고    scopus 로고
    • Neonatal immunity: Faulty T-helpers and the shortcomings of dendritic cells
    • Zaghouani, H., Hoeman, C. M. & Adkins, B. Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells. Trends Immunol. 30, 585-591 (2009).
    • (2009) Trends Immunol. , vol.30 , pp. 585-591
    • Zaghouani, H.1    Hoeman, C.M.2    Adkins, B.3
  • 14
    • 84893290244 scopus 로고    scopus 로고
    • Functional limitations of plasmacytoid dendritic cells limit type i interferon, T cell responses and virus control in early life
    • Belnoue, E. et al. Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life. PLoS. One. 8, e85302 (2013).
    • (2013) PLoS. One. , vol.8 , pp. e85302
    • Belnoue, E.1
  • 15
    • 0038722334 scopus 로고    scopus 로고
    • Efect of maternal antibodies on the infant immune response
    • Glezen, W. P. Efect of maternal antibodies on the infant immune response. Vaccine 21, 3389-3392 (2003).
    • (2003) Vaccine , vol.21 , pp. 3389-3392
    • Glezen, W.P.1
  • 16
    • 0037484129 scopus 로고    scopus 로고
    • Mechanisms by which maternal antibodies influence infant vaccine responses: Review of hypotheses and defnition of main determinants
    • Siegrist, C. A. Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and defnition of main determinants. Vaccine 21, 3406-3412 (2003).
    • (2003) Vaccine , vol.21 , pp. 3406-3412
    • Siegrist, C.A.1
  • 17
    • 0030929805 scopus 로고    scopus 로고
    • Fc receptor biology
    • Daeron, M. Fc receptor biology. Annu. Rev. Immunol. 15, 203-234 (1997).
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 203-234
    • Daeron, M.1
  • 18
    • 7744230151 scopus 로고    scopus 로고
    • Influence of complement C3 amount on IgG responses in early life: Immunization with C3b-conjugated antigen increases murine neonatal antibody responses
    • Pihlgren, M. et al. Influence of complement C3 amount on IgG responses in early life: immunization with C3b-conjugated antigen increases murine neonatal antibody responses. Vaccine 23, 329-335 (2004).
    • (2004) Vaccine , vol.23 , pp. 329-335
    • Pihlgren, M.1
  • 19
    • 0030593030 scopus 로고    scopus 로고
    • C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
    • Dempsey, P. W., Allison, M. E., Akkaraju, S., Goodnow, C. C. & Fearon, D. T. C3d of complement as a molecular adjuvant: bridging innate and acquired immunity. Science 271, 348-350 (1996).
    • (1996) Science , vol.271 , pp. 348-350
    • Dempsey, P.W.1    Allison, M.E.2    Akkaraju, S.3    Goodnow, C.C.4    Fearon, D.T.5
  • 20
    • 0034097043 scopus 로고    scopus 로고
    • Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex
    • Fearon, D. T. & Carroll, M. C. Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex. Annu. Rev. Immunol. 18, 393-422 (2000).
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 393-422
    • Fearon, D.T.1    Carroll, M.C.2
  • 21
    • 0023784428 scopus 로고
    • The complementary roles of cellular and humoral immunity in resistance to re-infection with LCM virus
    • Tomsen, A. R. & Marker, O. The complementary roles of cellular and humoral immunity in resistance to re-infection with LCM virus. Immunology 65, 9-15 (1988).
    • (1988) Immunology , vol.65 , pp. 9-15
    • Tomsen, A.R.1    Marker, O.2
  • 23
    • 49149117480 scopus 로고    scopus 로고
    • MHC class II-associated invariant chain linkage of antigen dramatically improves cell-mediated immunity induced by adenovirus vaccines
    • Holst, P. J. et al. MHC class II-associated invariant chain linkage of antigen dramatically improves cell-mediated immunity induced by adenovirus vaccines. J. Immunol. 180, 3339-3346 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 3339-3346
    • Holst, P.J.1
  • 24
    • 77952754236 scopus 로고    scopus 로고
    • Quality of the transgene-specifc CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination
    • Holst, P. J., Orskov, C., Tomsen, A. R. & Christensen, J. P. Quality of the transgene-specifc CD8+ T cell response induced by adenoviral vector immunization is critically influenced by virus dose and route of vaccination. J. Immunol. 184, 4431-4439 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 4431-4439
    • Holst, P.J.1    Orskov, C.2    Tomsen, A.R.3    Christensen, J.P.4
  • 25
    • 17044387019 scopus 로고    scopus 로고
    • Rapid functional exhaustion and deletion of CTL following immunization with recombinant adenovirus
    • Krebs, P., Scandella, E., Odermatt, B. & Ludewig, B. Rapid functional exhaustion and deletion of CTL following immunization with recombinant adenovirus. J. Immunol. 174, 4559-4566 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 4559-4566
    • Krebs, P.1    Scandella, E.2    Odermatt, B.3    Ludewig, B.4
  • 26
    • 34548862855 scopus 로고    scopus 로고
    • Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: Implications for their use as vaccines
    • Tatsis, N. et al. Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines. Blood 110, 1916-1923 (2007).
    • (2007) Blood , vol.110 , pp. 1916-1923
    • Tatsis, N.1
  • 27
    • 29644438544 scopus 로고    scopus 로고
    • The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity
    • Yang, T. C. et al. The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity. J. Immunol. 176, 200-210 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 200-210
    • Yang, T.C.1
  • 28
    • 0017290998 scopus 로고
    • The interplay between target organ concentrations of lymphocytic choriomeningitis virus and cell mediated immunity in baby mice
    • Marker, O., Torner, A. G. & Volkert, M. The interplay between target organ concentrations of lymphocytic choriomeningitis virus and cell mediated immunity in baby mice. Acta Pathol. Microbiol. Scand. C. 84, 23-30 (1976).
    • (1976) Acta Pathol. Microbiol. Scand. C. , vol.84 , pp. 23-30
    • Marker, O.1    Torner, A.G.2    Volkert, M.3
  • 29
    • 84885439255 scopus 로고    scopus 로고
    • Adenovirus-based vaccine against Listeria monocytogenes: Extending the concept of invariant chain linkage
    • Jensen, S. et al. Adenovirus-based vaccine against Listeria monocytogenes: extending the concept of invariant chain linkage. J. Immunol. 191, 4152-4164 (2013).
    • (2013) J. Immunol. , vol.191 , pp. 4152-4164
    • Jensen, S.1
  • 30
    • 49149117480 scopus 로고    scopus 로고
    • MHC class II-associated invariant chain linkage of antigen dramatically improves cell-mediated immunity induced by adenovirus vaccines
    • Holst, P. J. et al. MHC class II-associated invariant chain linkage of antigen dramatically improves cell-mediated immunity induced by adenovirus vaccines. J. Immunol. 180, 3339-3346 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 3339-3346
    • Holst, P.J.1
  • 31
    • 0023176193 scopus 로고
    • Mechanism of recovery from acute virus infection: Treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response
    • Moskophidis, D., Cobbold, S. P., Waldmann, H. & Lehmann-Grube, F. Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response. J. Virol. 61, 1867-1874 (1987).
    • (1987) J. Virol. , vol.61 , pp. 1867-1874
    • Moskophidis, D.1    Cobbold, S.P.2    Waldmann, H.3    Lehmann-Grube, F.4
  • 32
    • 79956320655 scopus 로고    scopus 로고
    • Protective capacity of memory CD8+ T cells is dictated by antigen exposure history and nature of the infection
    • Nolz, J. C. & Harty, J. T. Protective capacity of memory CD8+ T cells is dictated by antigen exposure history and nature of the infection. Immunity. 34, 781-793 (2011).
    • (2011) Immunity. , vol.34 , pp. 781-793
    • Nolz, J.C.1    Harty, J.T.2
  • 33
    • 84959475306 scopus 로고    scopus 로고
    • Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice
    • Bassi, M. R. et al. Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice. PLoS. Negl. Trop. Dis. 10, e0004464 (2016).
    • (2016) PLoS. Negl. Trop. Dis. , vol.10 , pp. e0004464
    • Bassi, M.R.1
  • 34
    • 80051882327 scopus 로고    scopus 로고
    • Tight regulation of memory CD8(+) T cells limits their efectiveness during sustained high viral load
    • West, E. E. et al. Tight regulation of memory CD8(+) T cells limits their efectiveness during sustained high viral load. Immunity. 35, 285-298 (2011).
    • (2011) Immunity. , vol.35 , pp. 285-298
    • West, E.E.1
  • 35
    • 84879562239 scopus 로고    scopus 로고
    • Efector-like CD8(+) T cells in the memory population mediate potent protective immunity
    • Olson, J. A., McDonald-Hyman, C., Jameson, S. C. & Hamilton, S. E. Efector-like CD8(+) T cells in the memory population mediate potent protective immunity. Immunity. 38, 1250-1260 (2013).
    • (2013) Immunity. , vol.38 , pp. 1250-1260
    • Olson, J.A.1    McDonald-Hyman, C.2    Jameson, S.C.3    Hamilton, S.E.4
  • 36
    • 0016232929 scopus 로고
    • Defects in the immune system of mice infected with lymphocytic choriomeningitis virus
    • Bro-Jorgensen, K. & Volkert, M. Defects in the immune system of mice infected with lymphocytic choriomeningitis virus. Infect. Immun. 9, 605-614 (1974).
    • (1974) Infect. Immun. , vol.9 , pp. 605-614
    • Bro-Jorgensen, K.1    Volkert, M.2
  • 37
    • 84859715603 scopus 로고    scopus 로고
    • Pre-existing vector immunity does not prevent replication defcient adenovirus from inducing efcient CD8 T-cell memory and recall responses
    • Stefensen, M. A. et al. Pre-existing vector immunity does not prevent replication defcient adenovirus from inducing efcient CD8 T-cell memory and recall responses. PLoS. One. 7, e34884 (2012).
    • (2012) PLoS. One. , vol.7 , pp. e34884
    • Stefensen, M.A.1
  • 38
    • 84878188022 scopus 로고    scopus 로고
    • Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: Not as bad as their reputation
    • Stefensen, M. A. et al. Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation. J. Virol. 87, 6283-6295 (2013).
    • (2013) J. Virol. , vol.87 , pp. 6283-6295
    • Stefensen, M.A.1
  • 39
    • 0034176037 scopus 로고    scopus 로고
    • Role of CD40 ligand and CD28 in induction and maintenance of antiviral CD8+ efector T cell responses
    • Andreasen, S. O., Christensen, J. E., Marker, O. & Tomsen, A. R. Role of CD40 ligand and CD28 in induction and maintenance of antiviral CD8+ efector T cell responses. J. Immunol. 164, 3689-3697 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 3689-3697
    • Andreasen, S.O.1    Christensen, J.E.2    Marker, O.3    Tomsen, A.R.4
  • 40
    • 33847410144 scopus 로고    scopus 로고
    • Increased female-male mortality ratio associated with inactivated polio and diphtheria-tetanus-pertussis vaccines: Observations from vaccination trials in Guinea-Bissau
    • Aaby, P. et al. Increased female-male mortality ratio associated with inactivated polio and diphtheria-tetanus-pertussis vaccines: Observations from vaccination trials in Guinea-Bissau. Pediatr. Infect. Dis. J. 26, 247-252 (2007).
    • (2007) Pediatr. Infect. Dis. J. , vol.26 , pp. 247-252
    • Aaby, P.1
  • 41
    • 33644899664 scopus 로고    scopus 로고
    • The sequence of vaccinations and increased female mortality afer high-titre measles vaccine: Trials from rural Sudan and Kinshasa
    • Aaby, P., Ibrahim, S. A., Libman, M. D. & Jensen, H. The sequence of vaccinations and increased female mortality afer high-titre measles vaccine: trials from rural Sudan and Kinshasa. Vaccine 24, 2764-2771 (2006).
    • (2006) Vaccine , vol.24 , pp. 2764-2771
    • Aaby, P.1    Ibrahim, S.A.2    Libman, M.D.3    Jensen, H.4
  • 42
    • 26844560753 scopus 로고    scopus 로고
    • Evaluation of non-specifc efects of infant immunizations on early infant mortality in a southern Indian population
    • Moulton, L. H. et al. Evaluation of non-specifc efects of infant immunizations on early infant mortality in a southern Indian population. Trop. Med. Int. Health 10, 947-955 (2005).
    • (2005) Trop. Med. Int. Health , vol.10 , pp. 947-955
    • Moulton, L.H.1
  • 43
    • 84884684153 scopus 로고    scopus 로고
    • Acute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses
    • Rudd, B. D. et al. Acute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses. PLoS. Pathog. 9, e1003572 (2013).
    • (2013) PLoS. Pathog. , vol.9 , pp. e1003572
    • Rudd, B.D.1
  • 44
    • 84958581057 scopus 로고    scopus 로고
    • The Neonatal CD8+ T Cell Repertoire Rapidly Diversifes during Persistent Viral Infection
    • Venturi, V. et al. The Neonatal CD8+ T Cell Repertoire Rapidly Diversifes during Persistent Viral Infection. J. Immunol. 196, 1604-1616 (2016).
    • (2016) J. Immunol. , vol.196 , pp. 1604-1616
    • Venturi, V.1
  • 45
    • 34548862855 scopus 로고    scopus 로고
    • Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: Implications for their use as vaccines
    • Tatsis, N. et al. Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines. Blood 110, 1916-1923 (2007).
    • (2007) Blood , vol.110 , pp. 1916-1923
    • Tatsis, N.1
  • 46
    • 70450184456 scopus 로고    scopus 로고
    • Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirus
    • Finn, J. D. et al. Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirus. J. Virol. 83, 12027-12036 (2009).
    • (2009) J. Virol. , vol.83 , pp. 12027-12036
    • Finn, J.D.1
  • 47
    • 33751224154 scopus 로고    scopus 로고
    • A correlation between function and selected measures of T cell avidity in infuenza virus-specifc CD8+ T cell responses
    • La Gruta, N. L., Doherty, P. C. & Turner, S. J. A correlation between function and selected measures of T cell avidity in infuenza virus-specifc CD8+ T cell responses. Eur. J. Immunol. 36, 2951-2959 (2006).
    • (2006) Eur. J. Immunol. , vol.36 , pp. 2951-2959
    • La Gruta, N.L.1    Doherty, P.C.2    Turner, S.J.3
  • 48
    • 24344478196 scopus 로고    scopus 로고
    • Type i interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • Kolumam, G. A., Tomas, S., Tompson, L. J., Sprent, J. & Murali-Krishna, K. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J. Exp. Med. 202, 637-650 (2005).
    • (2005) J. Exp. Med. , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Tomas, S.2    Tompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 49
    • 33645797125 scopus 로고    scopus 로고
    • CD8 T cells specifc for lymphocytic choriomeningitis virus require type i IFN receptor for clonal expansion
    • Aichele, P. et al. CD8 T cells specifc for lymphocytic choriomeningitis virus require type I IFN receptor for clonal expansion. J. Immunol. 176, 4525-4529 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 4525-4529
    • Aichele, P.1
  • 50
    • 84924067611 scopus 로고    scopus 로고
    • Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling
    • Quinn, K. M. et al. Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling. J. Clin. Invest 125, 1129-1146 (2015).
    • (2015) J. Clin. Invest , vol.125 , pp. 1129-1146
    • Quinn, K.M.1
  • 51
    • 84857640602 scopus 로고    scopus 로고
    • The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses
    • Bonilla, W. V. et al. The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses. Science 335, 984-989 (2012).
    • (2012) Science , vol.335 , pp. 984-989
    • Bonilla, W.V.1
  • 52
    • 73349130456 scopus 로고    scopus 로고
    • Neonatal innate TLR-mediated responses are distinct from those of adults
    • Kollmann, T. R. et al. Neonatal innate TLR-mediated responses are distinct from those of adults. J. Immunol. 183, 7150-7160 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 7150-7160
    • Kollmann, T.R.1
  • 53
    • 84940256794 scopus 로고    scopus 로고
    • New insight into an old concept: Role of immature erythroid cells in immune pathogenesis of neonatal infection
    • Elahi, S. New insight into an old concept: role of immature erythroid cells in immune pathogenesis of neonatal infection. Front Immunol. 5, 376 (2014).
    • (2014) Front Immunol. , vol.5 , pp. 376
    • Elahi, S.1
  • 54
    • 0032147017 scopus 로고    scopus 로고
    • Induction of neonatal TH1 and CTL responses by live viral vaccines: A role for replication patterns within antigen presenting cells?
    • Siegrist, C. A. et al. Induction of neonatal TH1 and CTL responses by live viral vaccines: a role for replication patterns within antigen presenting cells? Vaccine 16, 1473-1478 (1998).
    • (1998) Vaccine , vol.16 , pp. 1473-1478
    • Siegrist, C.A.1
  • 55
    • 0028690027 scopus 로고
    • Use of recombinant adenovirus for metabolic engineering of mammalian cells
    • Becker, T. C. et al. Use of recombinant adenovirus for metabolic engineering of mammalian cells. Methods Cell Biol. 43 Pt A, 161-189 (1994).
    • (1994) Methods Cell Biol. , vol.43 , pp. 161-189
    • Becker, T.C.1
  • 56
    • 0038128194 scopus 로고    scopus 로고
    • Cutting edge: Rapid in vivo killing by memory CD8 T cells
    • Barber, D. L., Wherry, E. J. & Ahmed, R. Cutting edge: rapid in vivo killing by memory CD8 T cells. J. Immunol. 171, 27-31 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 27-31
    • Barber, D.L.1    Wherry, E.J.2    Ahmed, R.3
  • 57
    • 84921507552 scopus 로고    scopus 로고
    • CD8+ T cells complement antibodies in protecting against yellow fever virus
    • Bassi, M. R. et al. CD8+ T cells complement antibodies in protecting against yellow fever virus. J. Immunol. 194, 1141-1153 (2015).
    • (2015) J. Immunol. , vol.194 , pp. 1141-1153
    • Bassi, M.R.1
  • 58
    • 0021723276 scopus 로고
    • Terapy with monoclonal antibodies by elimination of T-cell subsets in vivo
    • Cobbold, S. P., Jayasuriya, A., Nash, A., Prospero, T. D. & Waldmann, H. Terapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature 312, 548-551 (1984).
    • (1984) Nature , vol.312 , pp. 548-551
    • Cobbold, S.P.1    Jayasuriya, A.2    Nash, A.3    Prospero, T.D.4    Waldmann, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.