Acute Neonatal Infections 'Lock-In' a Suboptimal CD8+ T Cell Repertoire with Impaired Recall Responses

PLoS Pathogens

Volumn 9, Issue 9, 2013, Pages

  Rudd, Brian D ^a   Venturi, Vanessa ^b   Smith, Norah L ^a   Nzingha, Kito ^a   Goldberg, Emily L ^c   Li, Gang ^c   Nikolich Zugich, Janko ^c   Davenport, Miles P ^b  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; LIVE VACCINE; LYMPHOCYTE ANTIGEN RECEPTOR; RECOMBINANT DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL CLEARANCE; CD8+ T LYMPHOCYTE; CELL SELECTION; CONTROLLED STUDY; FLOW CYTOMETRY; HERPES SIMPLEX VIRUS 1; IMMUNE RESPONSE; LISTERIA MONOCYTOGENES; MEMORY T LYMPHOCYTE; MOUSE; NEWBORN; NEWBORN INFECTION; NONHUMAN; PROTECTION; RECEPTOR AFFINITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VACCINATION; VACCINIA VIRUS; AGING; ANIMAL; BIOLOGICAL MODEL; COMPARATIVE STUDY; GENETICS; GERMFREE ANIMAL; GROWTH, DEVELOPMENT AND AGING; HERPES SIMPLEX; IMMUNE SYSTEM; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; INBRED MOUSE STRAIN; LISTERIOSIS; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PATHOPHYSIOLOGY; VACCINIA; VIROLOGY; VIRULENCE;

AGING; ANIMALS; ANIMALS, NEWBORN; CD8-POSITIVE T-LYMPHOCYTES; DNA, RECOMBINANT; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNE SYSTEM; IMMUNOLOGIC DEFICIENCY SYNDROMES; IMMUNOLOGIC MEMORY; LISTERIA MONOCYTOGENES; LISTERIOSIS; MICE, INBRED STRAINS; MODELS, IMMUNOLOGICAL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SPECIFIC PATHOGEN-FREE ORGANISMS; VACCINES, ATTENUATED; VACCINIA; VACCINIA VIRUS; VIRULENCE;

EID: 84884684153     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003572     Document Type: Article

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