Curcumin attenuates paraquat-induced cell death in human neuroblastoma cells through modulating oxidative stress and autophagy

Neuroscience Letters

Volumn 636, Issue , 2017, Pages 40-47

  Jaroonwitchawan, Thiranut ^a   Chaicharoenaudomrung, Nipha ^a   Namkaew, Jirapat ^a   Noisa, Parinya ^a  

^a SURANAREE UNIVERSITY OF TECHNOLOGY   (Thailand)

Author keywords

Alzheimer's disease; Autophagy; Curcumin; Oxidative stress

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CHLOROQUINE; CURCUMIN; MESSENGER RNA; PARAQUAT; PROTEIN; REACTIVE OXYGEN METABOLITE; APP PROTEIN, HUMAN; NEUROPROTECTIVE AGENT; PRESENILIN 1; PRESENILIN 2;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL STRESS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SPACE; NEUROBLASTOMA CELL; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE;

AMYLOID BETA-PROTEIN PRECURSOR; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CURCUMIN; HUMANS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PARAQUAT; PRESENILIN-1; PRESENILIN-2; REACTIVE OXYGEN SPECIES;

EID: 85002168925     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2016.10.050     Document Type: Article

References (49)

1. [1] Aggarwal, M.L., Chacko, K.M., Kuruvilla, B.T., Systematic and comprehensive investigation of the toxicity of curcuminoidessential oil complex: a bioavailable turmeric formulation. Mol. Med. Rep. 13 (2016), 592–604.
2. [2] Aoki, H., Takada, Y., Kondo, S., Sawaya, R., Aggarwal, B.B., Kondo, Y., Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Mol. Pharmacol. 72 (2007), 29–39.
3. [3] Begum, A.N., Jones, M.R., Lim, G.P., Morihara, T., Kim, P., Heath, D.D., Rock, C.L., Pruitt, M.A., Yang, F., Hudspeth, B., Hu, S., Faull, K.F., Teter, B., Cole, G.M., Frautschy, S.A., Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease. J. Pharmacol. Exp. Ther. 326 (2008), 196–208.
4. [4] Boland, B., Kumar, A., Lee, S., Platt, F.M., Wegiel, J., Yu, W.H., Nixon, R.A., Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci. 28 (2008), 6926–6937.
5. [5] Chen, Y.W., Yang, Y.T., Hung, D.Z., Su, C.C., Chen, K.L., Paraquat induces lung alveolar epithelial cell apoptosis via Nrf-2-regulated mitochondrial dysfunction and ER stress. Arch. Toxicol. 86 (2012), 1547–1558.
6. [6] Csaki, C., Mobasheri, A., Shakibaei, M., Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis. Arthritis Res. Ther., 11, 2009, R165.
7. [7] Daverey, A., Agrawal, S.K., Curcumin alleviates oxidative stress and mitochondrial dysfunction in astrocytes. Neuroscience 333 (2016), 92–103.
8. [8] El-Bahr, S.M., Effect of curcumin on hepatic antioxidant enzymes activities and gene expressions in rats intoxicated with aflatoxin B1. Phytother. Res. 29 (2015), 134–140.
9. [9] Frautschy, S.A., Hu, W., Kim, P., Miller, S.A., Chu, T., Harris-White, M.E., Cole, G.M., Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology. Neurobiol. Aging 22 (2001), 993–1005.
10. [10] Fu, X.Y., Yang, M.F., Cao, M.Z., Li, D.W., Yang, X.Y., Sun, J.Y., Zhang, Z.Y., Mao, L.L., Zhang, S., Wang, F.Z., Zhang, F., Fan, C.D., Sun, B.L., Strategy to suppress oxidative damage-induced neurotoxicity in PC12Cells by curcumin: the role of ROS-Mediated DNA damage and the MAPK and AKT pathways. Mol. Neurobiol. 53 (2016), 369–378.
11. [11] Fujimori, K., Fukuhara, A., Inui, T., Allhorn, M., Prevention of paraquat-induced apoptosis in human neuronal SH-SY5Y cells by lipocalin-type prostaglandin D synthase. J. Neurochem. 120 (2012), 279–291.
12. [12] Garcia-Arencibia, M., Hochfeld, W.E., Toh, P.P., Rubinsztein, D.C., Autophagy, a guardian against neurodegeneration. Semin. Cell Dev. Biol. 21 (2010), 691–698.
13. [13] Gella, A., Durany, N., Oxidative stress in Alzheimer disease. Cell Adh. Migr. 3 (2009), 88–93.
14. [14] Hoehle, S.I., Pfeiffer, E., Solyom, A.M., Metzler, M., Metabolism of curcuminoids in tissue slices and subcellular fractions from rat liver. J. Agric. Food Chem. 54 (2006), 756–764.
15. [15] Holtzman, S., Ozanne, E., Carone, B., Goldstein, M.K., Steinke, G., Timbs, J., Decision analysis and Alzheimer disease: three case studies. Genet. Test. 3 (1999), 71–83.
16. [16] Huebbe, P., Jofre-Monseny, L., Boesch-Saadatmandi, C., Minihane, A.M., Rimbach, G., Effect of apoE genotype and vitamin E on biomarkers of oxidative stress in cultured neuronal cells and the brain of targeted replacement mice. J. Physiol. Pharmacol. 58 (2007), 683–698.
17. [17] Jager, R., Lowery, R.P., Calvanese, A.V., Joy, J.M., Purpura, M., Wilson, J.M., Comparative absorption of curcumin formulations. Nutr. J., 13, 2014, 11.
18. [18] Jofre-Monseny, L., Minihane, A.M., Rimbach, G., Impact of apoE genotype on oxidative stress, inflammation and disease risk. Mol. Nutr. Food Res. 52 (2008), 131–145.
19. [19] Jones, L., Harold, D., Williams, J., Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease. Biochim. Biophys. Acta 1801 (2010), 754–761.
20. [20] Kanai, M., Imaizumi, A., Otsuka, Y., Sasaki, H., Hashiguchi, M., Tsujiko, K., Matsumoto, S., Ishiguro, H., Chiba, T., Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers. Cancer Chemother. Pharmacol. 69 (2012), 65–70.
21. [21] Kim, J.Y., Cho, T.J., Woo, B.H., Choi, K.U., Lee, C.H., Ryu, M.H., Park, H.R., Curcumin-induced autophagy contributes to the decreased survival of oral cancer cells. Arch. Oral Biol. 57 (2012), 1018–1025.
22. [22] Klionsky, D.J., Emr, S.D., Autophagy as a regulated pathway of cellular degradation. Science 290 (2000), 1717–1721.
23. [23] Lee, H.J., Han, J., Jang, Y., Kim, S.J., Park, J.H., Seo, K.S., Jeong, S., Shin, S., Lim, K., Heo, J.Y., Kweon, G.R., Docosahexaenoic acid prevents paraquat-induced reactive oxygen species production in dopaminergic neurons via enhancement of glutathione homeostasis. Biochem. Biophys. Res. Commun. 457 (2015), 95–100.
24. [24] Lee, S., Sato, Y., Nixon, R.A., Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy. Autophagy 7 (2011), 1562–1563.
25. [25] Levine, B., Yuan, J., Autophagy in cell death: an innocent convict?. J. Clin. Invest. 115 (2005), 2679–2688.
26. [26] Li, Y., Li, J., Li, S., Li, Y., Wang, X., Liu, B., Fu, Q., Ma, S., Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK. Toxicol. Appl. Pharmacol. 286 (2015), 53–63.
27. [27] Lin, C.F., Yu, K.H., Jheng, C.P., Chung, R., Lee, C.I., Curcumin reduces amyloid fibrillation of prion protein and decreases reactive oxidative stress. Pathogens 2 (2013), 506–519.
28. [28] Martins, J.B., Bastos Mde, L., Carvalho, F., Capela, J.P., Differential effects of methyl-4-phenylpyridinium ion rotenone, and paraquat on differentiated SH-SY5Y cells. J. Toxicol., 2013, 2013, 347312.
29. [29] Masters, C.L., Simms, G., Weinman, N.A., Multhaup, G., McDonald, B.L., Beyreuther, K., Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl. Acad. Sci. U. S. A. 82 (1985), 4245–4249.
30. [30] Matsui, T., Ingelsson, M., Fukumoto, H., Ramasamy, K., Kowa, H., Frosch, M.P., Irizarry, M.C., Hyman, B.T., Expression of APP pathway mRNAs and proteins in Alzheimer's disease. Brain Res. 1161 (2007), 116–123.
31. [31] Mosieniak, G., Adamowicz, M., Alster, O., Jaskowiak, H., Szczepankiewicz, A.A., Wilczynski, G.M., Ciechomska, I.A., Sikora, E., Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy. Mech. Ageing Dev. 133 (2012), 444–455.
32. [32] Narayanan, A., Kehn-Hall, K., Senina, S., Lundberg, L., Van Duyne, R., Guendel, I., Das, R., Baer, A., Bethel, L., Turell, M., Hartman, A.L., Das, B., Bailey, C., Kashanchi, F., Curcumin inhibits Rift Valley fever virus replication in human cells. J. Biol. Chem. 287 (2012), 33198–33214.
33. [33] Nixon, R.A., Autophagy, amyloidogenesis and Alzheimer disease. J. Cell Sci. 120 (2007), 4081–4091.
34. [34] Nixon, R.A., Yang, D.S., Autophagy failure in Alzheimer's disease-locating the primary defect. Neurobiol. Dis. 43 (2011), 38–45.
35. [35] Ortiz-Ortiz, M.A., Moran, J.M., Ruiz-Mesa, L.M., Bonmatty, R.G., Fuentes, J.M., Protective effect of the glial cell line-derived neurotrophic factor (GDNF) on human mesencephalic neuron-derived cells against neurotoxicity induced by paraquat. Environ. Toxicol. Pharmacol. 31 (2011), 129–136.
36. [36] Perry, M.C., Demeule, M., Regina, A., Moumdjian, R., Beliveau, R., Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts. Mol. Nutr. Food Res. 54 (2010), 1192–1201.
37. [37] Pickford, F., Masliah, E., Britschgi, M., Lucin, K., Narasimhan, R., Jaeger, P.A., Small, S., Spencer, B., Rockenstein, E., Levine, B., Wyss-Coray, T., The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J. Clin. Invest. 118 (2008), 2190–2199.
38. [38] Rahmani, A.H., Al Zohairy, M.A., Aly, S.M., Khan, M.A., Curcumin: a potential candidate in prevention of cancer via modulation of molecular pathways. BioMed Res. Int., 2014, 2014, 761608.
39. [39] Ratnatilaka Na Bhuket, P., El-Magboub, A., Haworth, I.S., Rojsitthisak, P., Enhancement of curcumin bioavailability via the prodrug approach: challenges and prospects. Eur. J. Drug Metab. Pharmacokinet., 2016.
40. [40] Salvioli, S., Sikora, E., Cooper, E.L., Franceschi, C., Curcumin in cell death processes: a challenge for CAM of age-related pathologies. Evid. Based Complement. Altern. Med. 4 (2007), 181–190.
41. [41] Shakeri, A., Sahebkar, A., Optimized curcumin formulations for the treatment of Alzheimer's disease: a patent evaluation. J. Neurosci. Res. 94 (2016), 111–113.
42. [42] Trujillo, J., Chirino, Y.I., Molina-Jijon, E., Anderica-Romero, A.C., Tapia, E., Pedraza-Chaverri, J., Renoprotective effect of the antioxidant curcumin: recent findings. Redox Biol. 1 (2013), 448–456.
43. [43] Wang, L., Li, C., Guo, H., Kern, T.S., Huang, K., Zheng, L., Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury. PLoS One, 6, 2011, e23194.
44. [44] Wang, M.S., Boddapati, S., Emadi, S., Sierks, M.R., Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model. BMC Neurosci., 11, 2010, 57.
45. [45] Wang, R., Li, Y.B., Li, Y.H., Xu, Y., Wu, H.L., Li, X.J., Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB. Brain Res. 1210 (2008), 84–91.
46. [46] Wang, Y.J., Pan, M.H., Cheng, A.L., Lin, L.I., Ho, Y.S., Hsieh, C.Y., Lin, J.K., Stability of curcumin in buffer solutions and characterization of its degradation products. J. Pharm. Biomed. Anal. 15 (1997), 1867–1876.
47. [47] Yang, D.S., Stavrides, P., Mohan, P.S., Kaushik, S., Kumar, A., Ohno, M., Schmidt, S.D., Wesson, D.W., Bandyopadhyay, U., Jiang, Y., Pawlik, M., Peterhoff, C.M., Yang, A.J., Wilson, D.A., St George-Hyslop, P., Westaway, D., Mathews, P.M., Levy, E., Cuervo, A.M., Nixon, R.A., Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis. Autophagy 7 (2011), 788–789.
48. [48] Yarru, L.P., Settivari, R.S., Gowda, N.K., Antoniou, E., Ledoux, D.R., Rottinghaus, G.E., Effects of turmeric (Curcuma longa) on the expression of hepatic genes associated with biotransformation, antioxidant, and immune systems in broiler chicks fed aflatoxin. Poult. Sci. 88 (2009), 2620–2627.
49. [49] Zheng, S., Gao, X., Liu, X., Yu, T., Zheng, T., Wang, Y., You, C., Biodegradable micelles enhance the antiglioma activity of curcumin in vitro and in vivo. Int. J. Nanomed. 11 (2016), 2721–2736.