Prevention of paraquat-induced apoptosis in human neuronal SH-SY5Y cells by lipocalin-type prostaglandin D synthase

Journal of Neurochemistry

Volumn 120, Issue 2, 2012, Pages 279-291

  Fujimori, Ko ^a   Fukuhara, Ayano ^b   Inui, Takashi ^b   Allhorn, Maria ^c  

^a OSAKA MEDICAL COLLEGE   (Japan)

^b Osaka Prefecture University   (Japan)

^c LUND UNIVERSITY   (Sweden)

Author keywords

apoptosis; L PGDS; paraquat; SH SY5Y cells

Indexed keywords

ACTIN; CASPASE 3; CASPASE 9; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOCALIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARAQUAT; PROSTAGLANDIN D SYNTHASE; PROTEIN P50; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; SYNAPTOTAGMIN I;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPOPHILICITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; UPREGULATION;

APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; L-LACTATE DEHYDROGENASE; LIPOCALINS; NEUROBLASTOMA; NF-KAPPA B; PARAQUAT; PROSTAGLANDIN D2; PROTEIN BINDING; RNA, SMALL INTERFERING; STATISTICS, NONPARAMETRIC;

EID: 84155172357     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2011.07570.x     Document Type: Article

References (53)

1. Allhorn M., Berggard T., Nordberg J., Olsson M. L., and, Akerstrom B., (2002) Processing of the lipocalin alpha(1)-microglobulin by hemoglobin induces heme-binding and heme-degradation properties. Blood 99, 1894-1901. (Pubitemid 34525466)
2. Allhorn M., Klapyta A., and, Akerstrom B., (2005) Redox properties of the lipocalin alpha1-microglobulin: reduction of cytochrome c, hemoglobin, and free iron. Free Radic. Biol. Med. 38, 557-567. (Pubitemid 40416851)
3. Aritake K., Kado Y., Inoue T., Miyano M., and, Urade Y., (2006) Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase. J. Biol. Chem. 281, 15277-15286. (Pubitemid 43855117)
4. Berry C., La Vecchia C., and, Nicotera P., (2010) Paraquat and Parkinson's disease. Cell Death Differ. 17, 1115-1125.
5. Beuckmann C. T., Aoyagi M., Okazaki I., Hiroike T., Toh H., Hayaishi O., and, Urade Y., (1999) Binding of biliverdin, bilirubin, and thyroid hormones to lipocalin-type prostaglandin D synthase. Biochemistry 38, 8006-8013.
6. Brown T. P., Rumsby P. C., Capleton A. C., Rushton L., and, Levy L. S., (2006) Pesticides and Parkinson's disease-is there a link? Environ. Health Perspect. 114, 156-164. (Pubitemid 43193633)
7. Budihardjo I., Oliver H., Lutter M., Luo X., and, Wang X., (1999) Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15, 269-290. (Pubitemid 32250377)
8. Cartharius K., Frech K., Grote K., Klocke B., Haltmeier M., Klingenhoff A., Frisch M., Bayerlein M., and, Werner T., (2005) MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics 21, 2933-2942. (Pubitemid 40916416)
9. Castello P. R., Drechsel D. A., and, Patel M., (2007) Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain. J. Biol. Chem. 282, 14186-14193. (Pubitemid 47100444)
10. Chun H. S., Gibson G. E., DeGiorgio L. A., Zhang H., Kidd V. J., and, Son J. H., (2001) Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism. J. Neurochem. 76, 1010-1021. (Pubitemid 32167374)
11. Clausen J., (1961) Proteins in normal cerebrospinal fluid not found in serum. Proc. Soc. Exp. Biol. Med. 107, 170-172.
12. Costello S., Cockburn M., Bronstein J., Zhang X., and, Ritz B., (2009) Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California. Am. J. Epidemiol. 169, 919-926.
13. Devireddy L. R., Teodoro J. G., Richard F. A., and, Green M. R., (2001) Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation. Science 293, 829-834. (Pubitemid 32743967)
14. Dinis-Oliveira R. J., Remiao F., Carmo H., Duarte J. A., Navarro A. S., Bastos M. L., and, Carvalho F., (2006) Paraquat exposure as an etiological factor of Parkinson's disease. Neurotoxicology 27, 1110-1122. (Pubitemid 44838957)
15. Ecobichon D. J., (2001) Pesticide use in developing countries. Toxicology 160, 27-33. (Pubitemid 32200461)
16. Flower D. R., (2000) Experimentally determined lipocalin structures. Biochim. Biophys. Acta 1482, 46-56.
17. Franco R., Li S., Rodriguez-Rocha H., Burns M., and, Panayiotidis M. I., (2010) Molecular mechanisms of pesticide-induced neurotoxicity: Relevance to Parkinson's disease. Chem. Biol. Interact. 188, 289-300.
18. Fujimori K., Fujitani Y., Kadoyama K., Kumanogoh H., Ishikawa K., and, Urade Y., (2003) Regulation of lipocalin-type prostaglandin D synthase gene expression by Hes-1 through E-box and interleukin-1 beta via two NF-kappa B elements in rat leptomeningeal cells. J. Biol. Chem. 278, 6018-6026. (Pubitemid 36800852)
19. Fujimori K., Kadoyama K., and, Urade Y., (2005) Protein kinase C activates human lipocalin-type prostaglandin D synthase gene expression through de-repression of notch-HES signaling and enhancement of AP-2 beta function in brain-derived TE671 cells. J. Biol. Chem. 280, 18452-18461. (Pubitemid 41397966)
20. Fujimori K., Aritake K., and, Urade Y., (2007) A novel pathway to enhance adipocyte differentiation of 3T3-L1 cells by up-regulation of lipocalin-type prostaglandin D synthase mediated by liver X receptor-activated sterol regulatory element-binding protein-1c. J. Biol. Chem. 282, 18458-18466. (Pubitemid 47100233)
21. Fujimori K., Ueno T., Nagata N., Kashiwagi K., Aritake K., Amano F., and, Urade Y., (2010) Suppression of adipocyte differentiation by aldo-keto reductase 1B3 acting as prostaglandin F2alpha synthase. J. Biol. Chem. 285, 8880-8886.
22. Ganfornina M. D., Do Carmo S., Lora J. M., et al. (2008) Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress. Aging Cell 7, 506-515. (Pubitemid 351998611)
23. Ghosh A., Roy A., Liu X., et al. (2007) Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proc. Natl Acad. Sci. USA 104, 18754-18759. (Pubitemid 350210769)
24. Gonzalez-Polo R. A., Soler G., Rodriguezmartin A., Moran J. M., and, Fuentes J. M., (2004) Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants. Cell Biol. Int. 28, 373-380. (Pubitemid 38748927)
25. Helliwell R. J., Adams L. F., and, Mitchell M. D., (2004) Prostaglandin synthases: recent developments and a novel hypothesis. Prostaglandins Leukot. Essent. Fatty Acids 70, 101-113. (Pubitemid 38141900)
26. Hoffmann A., Conradt H. S., Gross G., Nimtz M., Lottspeich F., and, Wurster U., (1993) Purification and chemical characterization of beta-trace protein from human cerebrospinal fluid: its identification as prostaglandin D synthase. J. Neurochem. 61, 451-456. (Pubitemid 23215786)
27. Inui T., Ohkubo T., Urade Y., and, Hayaishi O., (1999) Enhancement of lipocalin-type prostaglandin D synthase enzyme activity by guanidine hydrochloride. Biochem. Biophys. Res. Commun. 266, 641-646. (Pubitemid 30042488)
28. Inui T., Ohkubo T., Emi M., Irikura D., Hayaishi O., and, Urade Y., (2003) Characterization of the unfolding process of lipocalin-type prostaglandin D synthase. J. Biol. Chem. 278, 2845-2852. (Pubitemid 36801188)
29. Kanekiyo T., Ban T., Aritake K., et al. (2007) Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid. Proc. Natl Acad. Sci. USA 104, 6412-6417. (Pubitemid 47186108)
30. Kuter K., Smialowska M., Wieronska J., et al. (2007) Toxic influence of subchronic paraquat administration on dopaminergic neurons in rats. Brain Res. 1155, 196-207. (Pubitemid 46891437)
31. Liou H. H., Chen R. C., Tsai Y. F., Chen W. P., Chang Y. C., and, Tsai M. C., (1996) Effects of paraquat on the substantia nigra of the wistar rats: neurochemical, histological, and behavioral studies. Toxicol. Appl. Pharmacol. 137, 34-41.
32. Maesaka J. K., Palaia T., Frese L., Fishbane S., and, Ragolia L., (2001) Prostaglandin D(2) synthase induces apoptosis in pig kidney LLC-PK1 cells. Kidney Int. 60, 1692-1698. (Pubitemid 32999973)
33. Manning-Bog A. B., McCormack A. L., Li J., Uversky V. N., Fink A. L., and, Di Monte D. A., (2002) The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein. J. Biol. Chem. 277, 1641-1644. (Pubitemid 34968732)
34. Mattson M. P., and, Meffert M. K., (2006) Roles for NF-kappaB in nerve cell survival, plasticity, and disease. Cell Death Differ. 13, 852-860.
35. McCormack A. L., Atienza J. G., Johnston L. C., Andersen J. K., Vu S., and, Di Monte D. A., (2005) Role of oxidative stress in paraquat-induced dopaminergic cell degeneration. J. Neurochem. 93, 1030-1037. (Pubitemid 40695762)
36. Mohri I., Taniike M., Okazaki I., et al. (2006) Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides. J. Neurochem. 97, 641-651.
37. Mollace V., Iannone M., Muscoli C., Palma E., Granato T., Rispoli V., Nistico R., Rotiroti D., and, Salvemini D., (2003) The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic. Neurosci. Lett. 335, 163-166. (Pubitemid 36071625)
38. Nagata N., Fujimori K., Okazaki I., Oda H., Eguchi N., Uehara Y., and, Urade Y., (2009) De novo synthesis, uptake and proteolytic processing of lipocalin-type prostaglandin D synthase, beta-trace, in the kidneys. FEBS J. 276, 7146-7158.
39. Patten D. A., Germain M., Kelly M. A., and, Slack R. S., (2010) Reactive oxygen species: stuck in the middle of neurodegeneration. J. Alzheimer's Dis. 20 (Suppl 2), S357-367.
40. Ragolia L., Palaia T., Frese L., Fishbane S., and, Maesaka J. K., (2001) Prostaglandin D2 synthase induces apoptosis in PC12 neuronal cells. Neuroreport 12, 2623-2628. (Pubitemid 32803189)
41. Schmidt-Ullrich R., Memet S., Lilienbaum A., Feuillard J., Raphael M., and, Israel A., (1996) NF-kappaB activity in transgenic mice: developmental regulation and tissue specificity. Development 122, 2117-2128. (Pubitemid 26235812)
42. Suntres Z. E., (2002) Role of antioxidants in paraquat toxicity. Toxicology 180, 65-77. (Pubitemid 35248093)
43. Tanaka T., Urade Y., Kimura H., Eguchi N., Nishikawa A., and, Hayaishi O., (1997) Lipocalin-type prostaglandin D synthase (beta-trace) is a newly recognized type of retinoid transporter. J. Biol. Chem. 272, 15789-15795. (Pubitemid 27265556)
44. Taniguchi H., Mohri I., Okabe-Arahori H., et al. (2007) Early induction of neuronal lipocalin-type prostaglandin D synthase after hypoxic-ischemic injury in developing brains. Neurosci. Lett. 420, 39-44. (Pubitemid 46777099)
45. Taniike M., Mohri I., Eguchi N., Beuckmann C. T., Suzuki K., and, Urade Y., (2002) Perineuronal oligodendrocytes protect against neuronal apoptosis through the production of lipocalin-type prostaglandin D synthase in a genetic demyelinating model. J. Neurosci. 22, 4885-4896. (Pubitemid 37465604)
46. Tanner C. M., Ottman R., Goldman S. M., Ellenberg J., Chan P., Mayeux R., and, Langston J. W., (1999) Parkinson disease in twins: an etiologic study. JAMA 281, 341-346. (Pubitemid 29061038)
47. Taylor J. M., and, Crack P. J., (2004) Impact of oxidative stress on neuronal survival. Clin. Exp. Pharmacol. Physiol. 31, 397-406. (Pubitemid 39044117)
48. Urade Y., and, Eguchi N., (2002) Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence. Prostaglandins Other Lipid Mediat. 68-69, 375-382. (Pubitemid 35247408)
49. Urade Y., Fujimoto N., and, Hayaishi O., (1985) Purification and characterization of rat brain prostaglandin D synthetase. J. Biol. Chem. 260, 12410-12415. (Pubitemid 16233440)
50. Urade Y., Tanaka T., Eguchi N., Kikuchi M., Kimura H., Toh H., and, Hayaishi O., (1995) Structural and functional significance of cysteine residues of glutathione-independent prostaglandin D synthase. Identification of Cys65 as an essential thiol. J. Biol. Chem. 270, 1422-1428.
51. Watanabe K., Urade Y., Mader M., Murphy C., and, Hayaishi O., (1994) Identification of beta-trace as prostaglandin D synthase. Biochem. Biophys. Res. Commun. 203, 1110-1116. (Pubitemid 2127858)
52. Yang W., Chen L., Ding Y., Zhuang X., and, Kang U. J., (2007) Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice. Hum. Mol. Genet. 16, 2900-2910. (Pubitemid 350048387)
53. Yang W., Tiffany-Castiglioni E., Lee M. Y., and, Son I. H., (2010) Paraquat induces cyclooxygenase-2 (COX-2) implicated toxicity in human neuroblastoma SH-SY5Y cells. Toxicol. Lett. 199, 239-246.