Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis

Autophagy

Volumn 7, Issue 7, 2011, Pages 788-789

  Yang, Dun Sheng ^a,b   Stavrides, Philip ^a   Mohan, Panaiyur S ^a,b   Kaushik, Susmita ^d   Kumar, Asok ^a,b   Ohno, Masuo ^a,b   Schmidt, Stephen D ^a   Wesson, Daniel W ^a,b   Bandyopadhyay, Urmi ^d   Jiang, Ying ^a,b   Pawlik, Monika ^a   Peterhoff, Corrinne M ^a   Yang, Austin J ^e   Wilson, Donald A ^a,b   St George Hyslop, Peter ^f   Westaway, David ^g   Mathews, Paul M ^a,b   Levy, Efrat ^a,b   Cuervo, Ana M ^d   Nixon, Ralph A ^a,b,c  

^a Nathan Kline Institute for Psychiatric Research   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF TORONTO   (Canada)

^g UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Alzheimer disease; Autophagy; Cathepsin; Cystatin B; Lysosome; Proteolysis; Transgenic

Indexed keywords

AMYLOID BETA PROTEIN; CATHEPSIN; CYSTATIN B; UBIQUITINATED PROTEIN;

ALZHEIMER DISEASE; AMNESIA; AUTOLYSOSOME; AUTOPHAGY; COGNITIVE DEFECT; LEARNING DISORDER; LYSOSOME; NONHUMAN; PATHOGENESIS; PROTEIN DEGRADATION; SHORT SURVEY; THERAPY EFFECT;

MUS;

EID: 79959979604     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.7.7.15596     Document Type: Short Survey

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