-
1
-
-
27744473566
-
Lost in translation: Barriers to implementing clinical immunotherapeutics for autoimmunity
-
Herrath, von M. G, & Nepom G. T. Lost in translation: barriers to implementing clinical immunotherapeutics for autoimmunity. J. Exp. Med. 202, 1159-1162 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 1159-1162
-
-
Herrath Von, M.G.1
Nepom, G.T.2
-
2
-
-
3042722266
-
Immunotherapy: Bewitched, bothered, and bewildered no more
-
Steinman R. M, & Mellman I. Immunotherapy: bewitched, bothered, and bewildered no more. Science 305, 197-200 (2004).
-
(2004)
Scienc
, vol.305
, pp. 197-200
-
-
Steinman, R.M.1
Mellman, I.2
-
3
-
-
57449096122
-
Prescription for human immunology
-
Davis M. M. A. Prescription for human immunology. Immunity 29, 835-838 (2008).
-
(2008)
Immunit
, vol.29
, pp. 835-838
-
-
Davis, M.M.A.1
-
4
-
-
79955008772
-
The human condition: An immunological perspective
-
Germain R. N, & Schwartzberg P. L. The human condition: an immunological perspective. Nat. Immunol. 12, 369-372 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 369-372
-
-
Germain, R.N.1
Schwartzberg, P.L.2
-
5
-
-
44049084451
-
The habitual, diverse and surmountable obstacles to human immunology research
-
Hayday A. C, & Peakman M. The habitual, diverse and surmountable obstacles to human immunology research. Nat. Immunol. 9, 575-580 (2008).
-
(2008)
Nat. Immunol
, vol.9
, pp. 575-580
-
-
Hayday, A.C.1
Peakman, M.2
-
6
-
-
84941803445
-
Systems vaccinology: Enabling rational vaccine design with systems biological approaches
-
Hagan T, Nakaya H. I, Subramaniam S, & Pulendran B. Systems vaccinology: enabling rational vaccine design with systems biological approaches. Vaccine 33, 5294-5301 (2015).
-
(2015)
Vaccin
, vol.33
, pp. 5294-5301
-
-
Hagan, T.1
Nakaya, H.I.2
Subramaniam, S.3
Pulendran, B.4
-
7
-
-
44449118948
-
Rapid cloning of high-Affinity human monoclonal antibodies against influenza virus
-
Wrammert J, et al. Rapid cloning of high-Affinity human monoclonal antibodies against influenza virus. Nature 453, 667-671 (2008).
-
(2008)
Natur
, vol.453
, pp. 667-671
-
-
Wrammert, J.1
-
8
-
-
84881434960
-
Dietary gluten triggers concomitant activation of CD4+ and CD8+ αβ T cells and γd T cells in celiac disease
-
Han A, et al. Dietary gluten triggers concomitant activation of CD4+ and CD8+ αβ T cells and γd T cells in celiac disease. Proc. Natl Acad. Sci. USA 110, 13073-13078 (2013).
-
(2013)
Proc. Natl Acad. Sci. US
, vol.110
, pp. 13073-13078
-
-
Han, A.1
-
9
-
-
33847302982
-
Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
-
Rαki M, et al. Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients. Proc. Natl Acad. Sci. USA 104, 2831-2836 (2007).
-
(2007)
Proc. Natl Acad. Sci. US
, vol.104
, pp. 2831-2836
-
-
Rki, M.1
-
10
-
-
84963547286
-
Powerful populations respond to viruses and vaccines
-
Brodin P. Powerful populations respond to viruses and vaccines. Immunity 43, 1035-1037 (2015).
-
(2015)
Immunit
, vol.43
, pp. 1035-1037
-
-
Brodin, P.1
-
11
-
-
84920982264
-
Variation in the human immune system is largely driven by non-heritable influences
-
Brodin P, et al. Variation in the human immune system is largely driven by non-heritable influences. Cell 160, 37-47 (2015).
-
(2015)
Cel
, vol.160
, pp. 37-47
-
-
Brodin, P.1
-
12
-
-
57849085182
-
Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans
-
Querec T. D, et al. Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans. Nat. Immunol. 10, 116-125 (2008).
-
(2008)
Nat. Immunol
, vol.10
, pp. 116-125
-
-
Querec, T.D.1
-
13
-
-
84963517248
-
Integrated, multi-cohort analysis identifies conserved transcriptional signatures across multiple respiratory viruses
-
Andres-Terre M, et al. Integrated, multi-cohort analysis identifies conserved transcriptional signatures across multiple respiratory viruses. Immunity 43, 1199-1211 (2015).
-
(2015)
Immunit
, vol.43
, pp. 1199-1211
-
-
Andres-Terre, M.1
-
14
-
-
84955127051
-
Adjuvanted influenza H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events
-
Sobolev O, et al. Adjuvanted influenza H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events. Nat. Immunol. 17, 204-213 (2016).
-
(2016)
Nat. Immunol
, vol.17
, pp. 204-213
-
-
Sobolev, O.1
-
15
-
-
84898653725
-
Global analyses of human immune variation reveal baseline predictors of postvaccination responses
-
Tsang J. S, et al. Global analyses of human immune variation reveal baseline predictors of postvaccination responses. Cell 157, 499-513 (2014).
-
(2014)
Cel
, vol.157
, pp. 499-513
-
-
Tsang, J.S.1
-
16
-
-
84958063966
-
The cellular composition of the human immune system is shaped by age and cohabitation
-
Carr E. J, et al. The cellular composition of the human immune system is shaped by age and cohabitation. Nat. Immunol. 17, 461-468 (2016).
-
(2016)
Nat. Immunol
, vol.17
, pp. 461-468
-
-
Carr, E.J.1
-
17
-
-
84994565969
-
Defective signaling in the JAK-STAT pathway tracks with chronic inflammation and cardiovascular risk in aging humans
-
e4
-
Shen-Orr S. S, et al. Defective signaling in the JAK-STAT pathway tracks with chronic inflammation and cardiovascular risk in aging humans. Cell Syst. 3, 374-384.e4 (2016).
-
(2016)
Cell Syst
, vol.3
, pp. 374-384
-
-
Shen-Orr, S.S.1
-
18
-
-
84903533463
-
Ontogeny of early life immunity
-
Dowling D. J, & Levy O. Ontogeny of early life immunity. Trends Immunol. 35, 299-310 (2014).
-
(2014)
Trends Immunol
, vol.35
, pp. 299-310
-
-
Dowling, D.J.1
Levy, O.2
-
19
-
-
84952047205
-
Evolution of the immune system in humans from infancy to old age
-
Simon A. K, Hollander G. A, & McMichael A. Evolution of the immune system in humans from infancy to old age. Proc. Biol. Sci. 282, 20143085 (2015).
-
(2015)
Proc. Biol. Sci
, vol.282
, pp. 20143085
-
-
Simon, A.K.1
Hollander, G.A.2
McMichael, A.3
-
20
-
-
68649122780
-
Neonates harbour highly active gammadelta T cells with selective impairments in preterm infants
-
Gibbons D. L, et al. Neonates harbour highly active gammadelta T cells with selective impairments in preterm infants. Eur. J. Immunol. 39, 1794-1806 (2009).
-
(2009)
Eur. J. Immunol
, vol.39
, pp. 1794-1806
-
-
Gibbons, D.L.1
-
21
-
-
84921957499
-
Interleukin 8 (CXCL8) production is a signatory T cell effector function of human newborn infants
-
Gibbons D, et al. Interleukin 8 (CXCL8) production is a signatory T cell effector function of human newborn infants. Nat. Med. 20, 1206-1210 (2014).
-
(2014)
Nat. Med
, vol.20
, pp. 1206-1210
-
-
Gibbons, D.1
-
22
-
-
84929246691
-
Systems vaccinology: A promise for the young and the poor
-
Amenyogbe N, Levy O, & Kollmann T. R. Systems vaccinology: a promise for the young and the poor. Phil. Trans. R. Soc. B, Biol. Sci. 370, 20140340 (2015).
-
(2015)
Phil. Trans. R. Soc. B, Biol. Sci
, vol.370
, pp. 20140340
-
-
Amenyogbe, N.1
Levy, O.2
Kollmann, T.R.3
-
23
-
-
84874092680
-
Lineage structure of the human antibody repertoire in response to influenza vaccination
-
Jiang N, et al. Lineage structure of the human antibody repertoire in response to influenza vaccination. Sci. Transl. Med. 5, 171ra19 (2013).
-
(2013)
Sci. Transl. Med
, vol.5
, pp. 171ra19
-
-
Jiang, N.1
-
24
-
-
2342527293
-
Aging, autoimmunity and arthritis: T cell senescence and contraction of T cell repertoire diversity - Catalysts of autoimmunity and chronic inflammation
-
Goronzy J. J, & Weyand C. M. Aging, autoimmunity and arthritis: T cell senescence and contraction of T cell repertoire diversity - catalysts of autoimmunity and chronic inflammation. Arthritis Res. Ther. 5, 225-234 (2003).
-
(2003)
Arthritis Res. Ther
, vol.5
, pp. 225-234
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
25
-
-
84907001176
-
Diversity and clonal selection in the human T cell repertoire
-
Qi Q, et al. Diversity and clonal selection in the human T cell repertoire. Proc. Natl Acad. Sci. USA 111, 13139-13144 (2014).
-
(2014)
Proc. Natl Acad. Sci. US
, vol.111
, pp. 13139-13144
-
-
Qi, Q.1
-
26
-
-
84896985687
-
Proinflammatory cytokines, aging, and age-related diseases
-
Michaud M, et al. Proinflammatory cytokines, aging, and age-related diseases. J. Am. Med. Dir. Assoc. 14, 877-882 (2013).
-
(2013)
J. Am. Med. Dir. Assoc
, vol.14
, pp. 877-882
-
-
Michaud, M.1
-
27
-
-
84907323440
-
Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs
-
Enroth S, Johansson Å, Enroth S. B, & Gyllensten U. Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. Nat. Commun. 5, 4684 (2014).
-
(2014)
Nat. Commun
, vol.5
, pp. 4684
-
-
Enroth, S.1
Johansson, Å.2
Enroth, S.B.3
Gyllensten, U.4
-
28
-
-
84876516949
-
Apoptosis and other immune biomarkers predict influenza vaccine responsiveness
-
Furman D, et al. Apoptosis and other immune biomarkers predict influenza vaccine responsiveness. Mol. Syst. Biol. 9, 659-659 (2013).
-
(2013)
Mol. Syst. Biol
, vol.9
, pp. 659
-
-
Furman, D.1
-
29
-
-
84963631903
-
Systems analysis of immunity to influenza vaccination across multiple years and in diverse populations reveals shared molecular signatures
-
Nakaya H. I, et al. Systems analysis of immunity to influenza vaccination across multiple years and in diverse populations reveals shared molecular signatures. Immunity 43, 1186-1198 (2015).
-
(2015)
Immunit
, vol.43
, pp. 1186-1198
-
-
Nakaya, H.I.1
-
30
-
-
67649756856
-
Seasonal variation of diagnosis of Type 1 diabetes mellitus in children worldwide
-
Moltchanova E. V, Schreier N, Lammi N, & Karvonen M. Seasonal variation of diagnosis of Type 1 diabetes mellitus in children worldwide. Diabet. Med. 26, 673-678 (2009).
-
(2009)
Diabet. Med
, vol.26
, pp. 673-678
-
-
Moltchanova, E.V.1
Schreier, N.2
Lammi, N.3
Karvonen, M.4
-
31
-
-
34347270615
-
What?s in season for rheumatoid arthritis patients? Seasonal fluctuations in disease activity
-
Iikuni N, et al. What?s in season for rheumatoid arthritis patients?. Seasonal fluctuations in disease activity. Rheumatology 46, 846-848 (2007).
-
(2007)
Rheumatolog
, vol.46
, pp. 846-848
-
-
Iikuni, N.1
-
32
-
-
84898790496
-
Seasonal changes in gene expression represent cell-Type composition in whole blood
-
De Jong S, et al. Seasonal changes in gene expression represent cell-Type composition in whole blood. Hum. Mol. Genet. 23, 2721-2728 (2014).
-
(2014)
Hum. Mol. Genet
, vol.23
, pp. 2721-2728
-
-
De Jong, S.1
-
33
-
-
84964294900
-
Widespread seasonal gene expression reveals annual differences in human immunity and physiology
-
Dopico X. C, et al. Widespread seasonal gene expression reveals annual differences in human immunity and physiology. Nat. Commun. 6, 7000 (2015).
-
(2015)
Nat. Commun
, vol.6
, pp. 7000
-
-
Dopico, X.C.1
-
34
-
-
33847025269
-
Circadian rhythms in rheumatoid arthritis: Implications for pathophysiology and therapeutic management
-
Straub R. H, & Cutolo M. Circadian rhythms in rheumatoid arthritis: implications for pathophysiology and therapeutic management. Arthritis Rheum. 56, 399-408 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 399-408
-
-
Straub, R.H.1
Cutolo, M.2
-
35
-
-
37649021327
-
Circadian rhythms in arthritis: Hormonal effects on the immune/ inflammatory reaction
-
Cutolo M, & Straub R. H. Circadian rhythms in arthritis: hormonal effects on the immune/ inflammatory reaction. Autoimmun Rev. 7, 223-228 (2008).
-
(2008)
Autoimmun Rev
, vol.7
, pp. 223-228
-
-
Cutolo, M.1
Straub, R.H.2
-
36
-
-
84894042926
-
Circadian clock proteins and immunity
-
Curtis A. M, Bellet M. M, Sassone-Corsi P, & O?Neill L. A. J. Circadian clock proteins and immunity. Immunity 40, 178-186 (2014).
-
(2014)
Immunit
, vol.40
, pp. 178-186
-
-
Curtis, A.M.1
Bellet, M.M.2
Sassone-Corsi, P.3
O'Neill, L.A.J.4
-
37
-
-
84965146271
-
Mass cytometry: Single cells, many features
-
Spitzer M. H, & Nolan G. P. Mass cytometry: single cells, many features. Cell 165, 780-791 (2016).
-
(2016)
Cel
, vol.165
, pp. 780-791
-
-
Spitzer, M.H.1
Nolan, G.P.2
-
38
-
-
80055072549
-
Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-Abundant proteins in human blood
-
Lundberg M, Eriksson A, Tran B, Assarsson E, & Fredriksson S. Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-Abundant proteins in human blood. Nucleic Acids Res. 39, e102 (2011).
-
(2011)
Nucleic Acids Res
, vol.39
, pp. e102
-
-
Lundberg, M.1
Eriksson, A.2
Tran, B.3
Assarsson, E.4
Fredriksson, S.5
-
39
-
-
84902478661
-
The use of multiplex platforms for absolute and relative protein quantification of clinical material
-
Christiansson L, et al. The use of multiplex platforms for absolute and relative protein quantification of clinical material. EuPA Open Proteom. 3, 37-47 (2014).
-
(2014)
EuPA Open Proteom
, vol.3
, pp. 37-47
-
-
Christiansson, L.1
-
40
-
-
84929162992
-
The genetic architecture of the human immune system: A bioresource for autoimmunity and disease pathogenesis
-
Roederer M, et al. The genetic architecture of the human immune system: a bioresource for autoimmunity and disease pathogenesis. Cell 161, 387-403 (2015).
-
(2015)
Cel
, vol.161
, pp. 387-403
-
-
Roederer, M.1
-
41
-
-
84962128086
-
Personalized immunomonitoring uncovers molecular networks that stratify lupus patients
-
Banchereau R, et al. Personalized immunomonitoring uncovers molecular networks that stratify lupus patients. Cell 165, 551-565 (2016).
-
(2016)
Cel
, vol.165
, pp. 551-565
-
-
Banchereau, R.1
-
42
-
-
0035554904
-
Sex differences in autoimmune disease
-
Whitacre C. C. Sex differences in autoimmune disease. Nat. Immunol. 2, 777-780 (2001).
-
(2001)
Nat. Immunol
, vol.2
, pp. 777-780
-
-
Whitacre, C.C.1
-
43
-
-
34248136519
-
Are there gender differences in severity of ankylosing spondylitis? Results from the PSOAS cohort
-
Lee W, et al. Are there gender differences in severity of ankylosing spondylitis?. Results from the PSOAS cohort. Ann. Rheum. Dis. 66, 633-638 (2007).
-
(2007)
Ann. Rheum. Dis
, vol.66
, pp. 633-638
-
-
Lee, W.1
-
44
-
-
0037452790
-
Individuality and variation in gene expression patterns in human blood
-
Whitney A. R, et al. Individuality and variation in gene expression patterns in human blood. Proc. Natl Acad. Sci. USA 100, 1896-1901 (2003).
-
(2003)
Proc. Natl Acad. Sci. US
, vol.100
, pp. 1896-1901
-
-
Whitney, A.R.1
-
45
-
-
4644327279
-
Sex hormones influence on the immune system: Basic and clinical aspects in autoimmunity
-
Cutolo M, et al. Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity. Lupus 13, 635-638 (2004).
-
(2004)
Lupu
, vol.13
, pp. 635-638
-
-
Cutolo, M.1
-
46
-
-
84892562675
-
Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination
-
Furman D, et al. Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination. Proc. Natl Acad. Sci. USA 111, 869-874 (2014).
-
(2014)
Proc. Natl Acad. Sci. US
, vol.111
, pp. 869-874
-
-
Furman, D.1
-
47
-
-
84901459546
-
ImmPort: Disseminating data to the public for the future of immunology
-
Bhattacharya S, et al. ImmPort: disseminating data to the public for the future of immunology. Immunol. Res. 58, 234-239 (2014).
-
(2014)
Immunol. Res
, vol.58
, pp. 234-239
-
-
Bhattacharya, S.1
-
48
-
-
0023870774
-
Genetic and environmental influences on premature death in adult adoptees
-
Sørensen T. I, Nielsen G. G, Andersen P. K, & Teasdale T. W. Genetic and environmental influences on premature death in adult adoptees. N. Engl. J. Med. 318, 727-732 (1988).
-
(1988)
N. Engl. J. Med
, vol.318
, pp. 727-732
-
-
Sørensen, T.I.1
Nielsen, G.G.2
Andersen, P.K.3
Teasdale, T.W.4
-
49
-
-
0347089095
-
The human model: A genetic dissection of immunity to infection in natural conditions
-
Casanova J. L, & Abel L. The human model: a genetic dissection of immunity to infection in natural conditions. Nat. Rev. Immunol. 4, 55-66 (2004).
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 55-66
-
-
Casanova, J.L.1
Abel, L.2
-
50
-
-
77957020774
-
Life-Threatening infectious diseases of childhood: Single-gene inborn errors of immunity?
-
Alcaïs A, et al. Life-Threatening infectious diseases of childhood: single-gene inborn errors of immunity?. Ann. NY Acad. Sci. 1214, 18-33 (2010).
-
(2010)
Ann. NY Acad. Sci
, vol.1214
, pp. 18-33
-
-
Alcaïs, A.1
-
51
-
-
84964644414
-
Genetics of autoimmune diseases: Perspectives from genome-wide association studies
-
Kochi Y. Genetics of autoimmune diseases: perspectives from genome-wide association studies. Int. Immunol. 28, 155-161 (2016).
-
(2016)
Int. Immunol
, vol.28
, pp. 155-161
-
-
Kochi, Y.1
-
52
-
-
67650709487
-
Recent advances in the genetics of autoimmune disease
-
Gregersen P. K, & Olsson L. M. Recent advances in the genetics of autoimmune disease. Annu. Rev. Immunol. 27, 363-391 (2009).
-
(2009)
Annu. Rev. Immunol
, vol.27
, pp. 363-391
-
-
Gregersen, P.K.1
Olsson, L.M.2
-
53
-
-
33748039452
-
Heritability of cardiovascular and personality traits in 6,148 sardinians
-
Pilia G, et al. Heritability of Cardiovascular and Personality Traits in 6,148 Sardinians. PLoS Genet. 2, e132 (2006).
-
(2006)
PLoS Genet
, vol.2
, pp. e132
-
-
Pilia, G.1
-
54
-
-
79959824142
-
Multiple loci are associated with white blood cell phenotypes
-
Nalls M. A, et al. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 7, e1002113 (2011).
-
(2011)
PLoS Genet
, vol.7
, pp. e1002113
-
-
Nalls, M.A.1
-
55
-
-
70349993594
-
Replication of celiac disease UK genome-wide association study results in a US population
-
Garner C. P, et al. Replication of celiac disease UK genome-wide association study results in a US population. Hum. Mol. Genet. 18, 4219-4225 (2009).
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 4219-4225
-
-
Garner, C.P.1
-
56
-
-
84884878742
-
Genetic variants regulating immune cell levels in health and disease
-
Orrù V, et al. Genetic variants regulating immune cell levels in health and disease. Cell 155, 242-256 (2013).
-
(2013)
Cel
, vol.155
, pp. 242-256
-
-
Orrù, V.1
-
57
-
-
33750378268
-
Systemic lupus erythematosus: All roads lead to type i interferons
-
Pascual V, Farkas L, & Banchereau J. Systemic lupus erythematosus: all roads lead to type I interferons. Curr. Opin. Immunol. 18, 676-682 (2006).
-
(2006)
Curr. Opin. Immunol
, vol.18
, pp. 676-682
-
-
Pascual, V.1
Farkas, L.2
Banchereau, J.3
-
58
-
-
76549136591
-
Genetic regulation of serum cytokines in systemic lupus erythematosus
-
Kariuki S. N, & Niewold T. B. Genetic regulation of serum cytokines in systemic lupus erythematosus. Translat. Res. 155, 109-117 (2010).
-
(2010)
Translat. Res
, vol.155
, pp. 109-117
-
-
Kariuki, S.N.1
Niewold, T.B.2
-
59
-
-
0344492212
-
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
-
Baechler E. C, et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc. Natl Acad. Sci. USA 100, 2610-2615 (2003).
-
(2003)
Proc. Natl Acad. Sci. US
, vol.100
, pp. 2610-2615
-
-
Baechler, E.C.1
-
60
-
-
34548438559
-
High serum IFN-α activity is a heritable risk factor for systemic lupus erythematosus
-
Niewold T. B, Hua J, Lehman T. J. A, Harley J. B, & Crow M. K. High serum IFN-α activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun. 8, 492-502 (2007).
-
(2007)
Genes Immun
, vol.8
, pp. 492-502
-
-
Niewold, T.B.1
Hua, J.2
Lehman, T.J.A.3
Harley, J.B.4
Crow, M.K.5
-
61
-
-
84888198427
-
Novel gene variants predict serum levels of the cytokines IL 18 and IL 1ra in older adults
-
Matteini A. M, et al. Novel gene variants predict serum levels of the cytokines IL 18 and IL 1ra in older adults. Cytokine 65, 10-16 (2014).
-
(2014)
Cytokin
, vol.65
, pp. 10-16
-
-
Matteini, A.M.1
-
62
-
-
9644304486
-
Cytokine genes and disease susceptibility
-
Ollier W. E. R. Cytokine genes and disease susceptibility. Cytokine 28, 174-178 (2004).
-
(2004)
Cytokin
, vol.28
, pp. 174-178
-
-
Ollier, W.E.R.1
-
63
-
-
84928695024
-
ImmVar project: Insights and design considerations for future studies of 'healthy' immune variation
-
De Jager P. L, et al. ImmVar project: insights and design considerations for future studies of ?healthy? immune variation. Semin. Immunol. 27, 51-57 (2015).
-
(2015)
Semin. Immunol
, vol.27
, pp. 51-57
-
-
De Jager, P.L.1
-
64
-
-
79952263851
-
Single-Tissue and cross-Tissue heritability of gene expression via identity-by descent in related or unrelated individuals
-
Price A. L, et al. Single-Tissue and cross-Tissue heritability of gene expression via identity-by descent in related or unrelated individuals. PLoS Genet. 7, e1001317 (2011).
-
(2011)
PLoS Genet
, vol.7
, pp. e1001317
-
-
Price, A.L.1
-
65
-
-
84971320925
-
Drug-induced mRNA signatures are enriched for the minority of genes that are highly heritable
-
Gao T, Brodin P, Davis M. M, & Jojic V. Drug-induced mRNA signatures are enriched for the minority of genes that are highly heritable. Pac. Symp. Biocomput. 395-406 (2015).
-
(2015)
Pac. Symp. Biocomput
, pp. 395-406
-
-
Gao, T.1
Brodin, P.2
Davis, M.M.3
Jojic, V.4
-
66
-
-
84896759364
-
Common genetic variants modulate pathogen-sensing responses in human dendritic cells
-
Lee M. N, et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science 343, 1246980 (2014).
-
(2014)
Scienc
, vol.343
, pp. 1246980
-
-
Lee, M.N.1
-
67
-
-
84907202723
-
Intersection of population variation and autoimmunity genetics in human T cell activation
-
Ye C. J, et al. Intersection of population variation and autoimmunity genetics in human T cell activation. Science 345, 1254665 (2014).
-
(2014)
Scienc
, vol.345
, pp. 1254665
-
-
Ye, C.J.1
-
68
-
-
0026443849
-
Adaptive cellular interactions in the immune system: The tunable activation threshold and the significance of subthreshold responses
-
Grossman Z, & Paul W. E. Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses. Proc. Natl Acad. Sci. USA 89, 10365-10369 (1992).
-
(1992)
Proc. Natl Acad. Sci. US
, vol.89
, pp. 10365-10369
-
-
Grossman, Z.1
Paul, W.E.2
-
69
-
-
63149126181
-
NK cell education: Not an on off switch but a tunable rheostat
-
Brodin P, Krre K, & Hqglund P. NK cell education: not an on off switch but a tunable rheostat. Trends Immunol. 30, 143-149 (2009).
-
(2009)
Trends Immunol
, vol.30
, pp. 143-149
-
-
Brodin, P.1
Krre, K.2
Hqglund, P.3
-
70
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga M. F, et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl Acad. Sci. USA 102, 10604-10609 (2005).
-
(2005)
Proc. Natl Acad. Sci. US
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
-
71
-
-
84977481546
-
Epigenome-wide association studies and the interpretation of disease-omics
-
Birney E, Smith G. D, & Greally J. M. Epigenome-wide association studies and the interpretation of disease-omics. PLoS Genet. 12, e1006105 (2016).
-
(2016)
PLoS Genet
, vol.12
, pp. e1006105
-
-
Birney, E.1
Smith, G.D.2
Greally, J.M.3
-
72
-
-
84965002935
-
How colonization by microbiota in early life shapes the immune system
-
Gensollen T, Iyer S. S, Kasper D. L, & Blumberg R. S. How colonization by microbiota in early life shapes the immune system. Science 352, 539-544 (2016).
-
(2016)
Scienc
, vol.352
, pp. 539-544
-
-
Gensollen, T.1
Iyer, S.S.2
Kasper, D.L.3
Blumberg, R.S.4
-
73
-
-
84862637797
-
Gut immune maturation depends on colonization with a host-specific microbiota
-
Chung H, et al. Gut immune maturation depends on colonization with a host-specific microbiota. Cell 149, 1578-1593 (2012).
-
(2012)
Cel
, vol.149
, pp. 1578-1593
-
-
Chung, H.1
-
74
-
-
84964918435
-
Normalizing the environment recapitulates adult human immune traits in laboratory mice
-
Beura L. K, et al. Normalizing the environment recapitulates adult human immune traits in laboratory mice. Nature 532, 512-516 (2016).
-
(2016)
Natur
, vol.532
, pp. 512-516
-
-
Beura, L.K.1
-
75
-
-
84963983980
-
Sequential infection with common pathogens promotes human-like immune gene expression and altered vaccine response
-
Reese T. A, et al. Sequential infection with common pathogens promotes human-like immune gene expression and altered vaccine response. Cell Host Microbe 19, 713-719 (2016).
-
(2016)
Cell Host Microb
, vol.19
, pp. 713-719
-
-
Reese, T.A.1
-
76
-
-
0024417450
-
Hay fever, hygiene, and household size
-
Strachan D. P. Hay fever, hygiene, and household size. BMJ 299, 1259-1260 (1989).
-
(1989)
BM
, vol.299
, pp. 1259-1260
-
-
Strachan, D.P.1
-
77
-
-
0037136537
-
The effect of infections on susceptibility to autoimmune and allergic diseases
-
Bach J. F. The effect of infections on susceptibility to autoimmune and allergic diseases. N. Engl. J. Med. 347, 911-920 (2002).
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 911-920
-
-
Bach, J.F.1
-
78
-
-
0037136585
-
Environmental exposure to endotoxin and its relation to asthma in school-Age children
-
Braun-Fahrldnder C, et al. Environmental exposure to endotoxin and its relation to asthma in school-Age children. N. Engl. J. Med. 347, 869-877 (2002).
-
(2002)
N. Engl. J. Med
, vol.347
, pp. 869-877
-
-
Braun-Fahrldnder, C.1
-
79
-
-
84964682615
-
Variation in microbiome LPS immunogenicity contributes to autoimmunity in humans
-
Vatanen T, et al. Variation in microbiome LPS immunogenicity contributes to autoimmunity in humans. Cell 165, 842-853 (2016).
-
(2016)
Cel
, vol.165
, pp. 842-853
-
-
Vatanen, T.1
-
80
-
-
84942874856
-
Early infancy microbial and metabolic alterations affect risk of childhood asthma
-
Arrieta M. C, et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci. Transl. Med. 7, 307ra152 (2015).
-
(2015)
Sci. Transl. Med
, vol.7
, pp. 307ra152
-
-
Arrieta, M.C.1
-
81
-
-
84907557973
-
The microbial basis of inflammatory bowel diseases
-
Dalal S. R, & Chang E. B. The microbial basis of inflammatory bowel diseases. J. Clin. Invest. 124, 4190-4196 (2014).
-
(2014)
J. Clin. Invest
, vol.124
, pp. 4190-4196
-
-
Dalal, S.R.1
Chang, E.B.2
-
82
-
-
84861539347
-
Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation
-
Jenq R. R, et al. Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation. J. Exp. Med. 209, 903-911 (2012).
-
(2012)
J. Exp. Med
, vol.209
, pp. 903-911
-
-
Jenq, R.R.1
-
83
-
-
84908003512
-
TLR5 mediated sensing of gut microbiota Is necessary for antibody responses to seasonal influenza vaccination
-
Oh J. Z, et al. TLR5 mediated sensing of gut microbiota Is necessary for antibody responses to seasonal influenza vaccination. Immunity 41, 478-492 (2014).
-
(2014)
Immunit
, vol.41
, pp. 478-492
-
-
Oh, J.Z.1
-
84
-
-
84888059687
-
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide
-
Viaud S, et al. The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 342, 971-976 (2013).
-
(2013)
Scienc
, vol.342
, pp. 971-976
-
-
Viaud, S.1
-
85
-
-
84948461699
-
Anticancer immunotherapy by CTLA 4 blockade relies on the gut microbiota
-
V?tizou M, et al. Anticancer immunotherapy by CTLA 4 blockade relies on the gut microbiota. Science 350, 1079-1084 (2015).
-
(2015)
Scienc
, vol.350
, pp. 1079-1084
-
-
Vtizou, M.1
-
86
-
-
84948451779
-
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti PD L1 efficacy
-
Sivan A, et al. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti PD L1 efficacy. Science 350, 1084-1089 (2015).
-
(2015)
Scienc
, vol.350
, pp. 1084-1089
-
-
Sivan, A.1
-
87
-
-
84930635082
-
Viral immunology Comprehensive serological profiling of human populations using a synthetic human virome
-
Xu G. J, et al. Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome. Science 348, aaa0698 (2015).
-
(2015)
Scienc
, vol.348
, pp. aaa0698
-
-
Xu, G.J.1
-
88
-
-
24344489044
-
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects
-
Sylwester A. W, et al. Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J. Exp. Med. 202, 673-685 (2005).
-
(2005)
J. Exp. Med
, vol.202
, pp. 673-685
-
-
Sylwester, A.W.1
-
89
-
-
84959559396
-
Immune adaptation to environmental influence: The case of NK cells and HCMV
-
Rqlle A, & Brodin P. Immune adaptation to environmental influence: the case of NK cells and HCMV. Trends Immunol. 37, 233-243 (2016).
-
(2016)
Trends Immunol
, vol.37
, pp. 233-243
-
-
Rqlle, A.1
Brodin, P.2
-
90
-
-
84926442317
-
Cytomegalovirus infection enhances the immune response to influenza
-
Furman D, et al. Cytomegalovirus infection enhances the immune response to influenza. Sci Transl Med 7, 281ra43 (2015).
-
(2015)
Sci Transl Me
, vol.7
, pp. 281ra43
-
-
Furman, D.1
-
91
-
-
84897127283
-
The virome in mammalian physiology and disease
-
Virgin H. W. The virome in mammalian physiology and disease. Cell 157, 142-150 (2014).
-
(2014)
Cel
, vol.157
, pp. 142-150
-
-
Virgin, H.W.1
-
92
-
-
84889594211
-
Temporal response of the human virome to immunosuppression and antiviral therapy
-
De Vlaminck I, et al. Temporal response of the human virome to immunosuppression and antiviral therapy. Cell 155, 1178-1187 (2013).
-
(2013)
Cel
, vol.155
, pp. 1178-1187
-
-
De Vlaminck, I.1
-
93
-
-
0036580648
-
Effects of cigarette smoke on the immune system
-
Sopori M. Effects of cigarette smoke on the immune system. Nat. Rev. Immunol. 2, 372-377 (2002).
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 372-377
-
-
Sopori, M.1
-
94
-
-
84982267484
-
Current cigarette smoking is a reversible cause of elevated white blood cell count: Cross-sectional and longitudinal studies
-
Higuchi T, et al. Current cigarette smoking is a reversible cause of elevated white blood cell count: cross-sectional and longitudinal studies. Prev. Med. Rep. 4, 417-422 (2016).
-
(2016)
Prev. Med. Rep
, vol.4
, pp. 417-422
-
-
Higuchi, T.1
-
95
-
-
0018766244
-
Low natural killer-cell activity and immunoglobulin levels associated with smoking in human subjects
-
Ferson M, Edwards A, Lind A, Milton G. W, & Hersey P. Low natural killer-cell activity and immunoglobulin levels associated with smoking in human subjects. Int. J. Cancer 23, 603-609 (1979).
-
(1979)
Int. J. Cance
, vol.23
, pp. 603-609
-
-
Ferson, M.1
Edwards, A.2
Lind, A.3
Milton, G.W.4
Hersey, P.5
-
96
-
-
0015901245
-
Association of autoantibodies with smoking, cardiovascular morbidity, and death in the Busselton population
-
Mathews J. D, Whittingham S, Hooper B. M, Mackay I. R, & Stenhouse N. S. Association of autoantibodies with smoking, cardiovascular morbidity, and death in the Busselton population. Lancet 2, 754-758 (1973).
-
(1973)
Lance
, vol.2
, pp. 754-758
-
-
Mathews, J.D.1
Whittingham, S.2
Hooper, B.M.3
Mackay, I.R.4
Stenhouse, N.S.5
-
97
-
-
5644239636
-
A gene-environment interaction between smoking and shared epitope genes in HLA DR provides a high risk of seropositive rheumatoid arthritis
-
Padyukov L, et al. A gene-environment interaction between smoking and shared epitope genes in HLA DR provides a high risk of seropositive rheumatoid arthritis. Arthritis Rheum. 50, 3085-3092 (2004).
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3085-3092
-
-
Padyukov, L.1
-
98
-
-
84928053009
-
A mine is a terrible thing to waste: High content, single cell technologies for comprehensive immune analysis
-
Chattopadhyay P. K, & Roederer M. A mine is a terrible thing to waste: high content, single cell technologies for comprehensive immune analysis. Am. J. Transplant. 15, 1155-1161 (2015).
-
(2015)
Am. J Transplant
, vol.15
, pp. 1155-1161
-
-
Chattopadhyay, P.K.1
Roederer, M.2
-
99
-
-
68849103521
-
Mass cytometry: Technique for real time single cell multitarget immunoassay based on inductively coupled plasma time of flight mass spectrometry
-
Bandura D. R, et al. Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time of flight mass spectrometry. Anal. Chem. 81, 6813-6822 (2009).
-
(2009)
Anal. Chem
, vol.81
, pp. 6813-6822
-
-
Bandura, D.R.1
-
100
-
-
84959248377
-
Highly multiplexed simultaneous detection of RNAs and proteins in single cells
-
Frei A. P, et al. Highly multiplexed simultaneous detection of RNAs and proteins in single cells. Nat. Methods 13, 269-275 (2016).
-
(2016)
Nat. Method
, vol.13
, pp. 269-275
-
-
Frei, A.P.1
-
101
-
-
84856278095
-
Cytometry by time of flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes
-
Newell E. W, Sigal N, Bendall S. C, Nolan G. P, & Davis M. M. Cytometry by time of flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes. Immunity 36, 142-152 (2012).
-
(2012)
Immunit
, vol.36
, pp. 142-152
-
-
Newell, E.W.1
Sigal, N.2
Bendall, S.C.3
Nolan, G.P.4
Davis, M.M.5
-
102
-
-
84866096861
-
Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators
-
Bodenmiller B, et al. Multiplexed mass cytometry profiling of cellular states perturbed by small-molecule regulators. Nat. Biotechnol. 30, 858-867 (2012).
-
(2012)
Nat. Biotechnol
, vol.30
, pp. 858-867
-
-
Bodenmiller, B.1
-
103
-
-
79955750055
-
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum
-
Bendall S. C, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science 332, 687-696 (2011).
-
(2011)
Scienc
, vol.332
, pp. 687-696
-
-
Bendall, S.C.1
-
104
-
-
84929684999
-
Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets
-
Macosko E. Z, et al. Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets. Cell 161, 1202-1214 (2015).
-
(2015)
Cel
, vol.161
, pp. 1202-1214
-
-
Macosko, E.Z.1
-
105
-
-
84903993800
-
Linking T cell receptor sequence to functional phenotype at the single-cell level
-
Han A, Glanville J, Hansmann L, & Davis M. M. Linking T cell receptor sequence to functional phenotype at the single-cell level. Nat. Biotechnol. 32, 684-692 (2014).
-
(2014)
Nat. Biotechnol
, vol.32
, pp. 684-692
-
-
Han, A.1
Glanville, J.2
Hansmann, L.3
Davis, M.M.4
-
106
-
-
84960194523
-
T cell fate and clonality inference from single-cell transcriptomes
-
Stubbington M. J. T, et al. T cell fate and clonality inference from single-cell transcriptomes. Nat. Method 13 329-332 (2016).
-
(2016)
Nat. Methods
, vol.13
, pp. 329-332
-
-
Stubbington, M.J.T.1
-
107
-
-
84904305923
-
Mass spectrometry-based plasma proteomics: State of the art and future outlook
-
Pernemalm M, & Lehtiö J. Mass spectrometry-based plasma proteomics: state of the art and future outlook. Expert Rev. Proteom. 11, 431-448 (2014).
-
(2014)
Expert Rev. Proteom
, vol.11
, pp. 431-448
-
-
Pernemalm, M.1
Lehtiö, J.2
|