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Volumn 30, Issue 4, 2009, Pages 143-149

NK cell education: not an on-off switch but a tunable rheostat

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MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

EID: 63149126181     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2009.01.006     Document Type: Article
Times cited : (205)

References (48)
  • 1
    • 0035059950 scopus 로고    scopus 로고
    • Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
    • Moretta A., et al. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19 (2001) 197-223
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 197-223
    • Moretta, A.1
  • 2
    • 44949266455 scopus 로고
    • In search of the 'missing self': MHC molecules and NK cell recognition
    • Ljunggren H.G., and Karre K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 11 (1990) 237-244
    • (1990) Immunol. Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Karre, K.2
  • 3
    • 0035874543 scopus 로고    scopus 로고
    • Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo
    • Koh C.Y., et al. Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo. Blood 97 (2001) 3132-3137
    • (2001) Blood , vol.97 , pp. 3132-3137
    • Koh, C.Y.1
  • 4
    • 0032006398 scopus 로고    scopus 로고
    • NK cell granule exocytosis and cytokine production inhibited by Ly-49A engagement
    • Kim S., and Yokoyama W.M. NK cell granule exocytosis and cytokine production inhibited by Ly-49A engagement. Cell. Immunol. 183 (1998) 106-112
    • (1998) Cell. Immunol. , vol.183 , pp. 106-112
    • Kim, S.1    Yokoyama, W.M.2
  • 5
    • 0037108428 scopus 로고    scopus 로고
    • Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens
    • Raziuddin A., et al. Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens. Blood 100 (2002) 3026-3033
    • (2002) Blood , vol.100 , pp. 3026-3033
    • Raziuddin, A.1
  • 6
    • 0032538916 scopus 로고    scopus 로고
    • Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b)
    • Vance R.E., et al. Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). J. Exp. Med. 188 (1998) 1841-1848
    • (1998) J. Exp. Med. , vol.188 , pp. 1841-1848
    • Vance, R.E.1
  • 7
    • 0022616253 scopus 로고
    • Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy
    • Karre K., et al. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. Nature 319 (1986) 675-678
    • (1986) Nature , vol.319 , pp. 675-678
    • Karre, K.1
  • 8
    • 42449102990 scopus 로고    scopus 로고
    • Up on the tightrope: natural killer cell activation and inhibition
    • Lanier L.L. Up on the tightrope: natural killer cell activation and inhibition. Nat. Immunol. 9 (2008) 495-502
    • (2008) Nat. Immunol. , vol.9 , pp. 495-502
    • Lanier, L.L.1
  • 9
    • 0023715513 scopus 로고
    • Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice
    • Hoglund P., et al. Natural resistance against lymphoma grafts conveyed by H-2Dd transgene to C57BL mice. J. Exp. Med. 168 (1988) 1469-1474
    • (1988) J. Exp. Med. , vol.168 , pp. 1469-1474
    • Hoglund, P.1
  • 10
    • 17144365824 scopus 로고    scopus 로고
    • Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules
    • Johansson S., et al. Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules. J. Exp. Med. 201 (2005) 1145-1155
    • (2005) J. Exp. Med. , vol.201 , pp. 1145-1155
    • Johansson, S.1
  • 11
    • 0029797865 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire
    • Held W., et al. Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire. Eur. J. Immunol. 26 (1996) 2286-2292
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2286-2292
    • Held, W.1
  • 12
    • 0031053169 scopus 로고    scopus 로고
    • Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors
    • Raulet D.H., et al. Specificity, tolerance and developmental regulation of natural killer cells defined by expression of class I-specific Ly49 receptors. Immunol. Rev. 155 (1997) 41-52
    • (1997) Immunol. Rev. , vol.155 , pp. 41-52
    • Raulet, D.H.1
  • 13
    • 0031406018 scopus 로고    scopus 로고
    • Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors
    • Valiante N.M., et al. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity 7 (1997) 739-751
    • (1997) Immunity , vol.7 , pp. 739-751
    • Valiante, N.M.1
  • 14
    • 33747101972 scopus 로고    scopus 로고
    • Human NK cell education by inhibitory receptors for MHC class I
    • Anfossi N., et al. Human NK cell education by inhibitory receptors for MHC class I. Immunity 25 (2006) 331-342
    • (2006) Immunity , vol.25 , pp. 331-342
    • Anfossi, N.1
  • 15
    • 0026032210 scopus 로고
    • Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice
    • Bix M., et al. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice. Nature 349 (1991) 329-331
    • (1991) Nature , vol.349 , pp. 329-331
    • Bix, M.1
  • 16
    • 0025880648 scopus 로고
    • MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity
    • Liao N.S., et al. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253 (1991) 199-202
    • (1991) Science , vol.253 , pp. 199-202
    • Liao, N.S.1
  • 17
    • 0025789740 scopus 로고
    • Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice
    • Hoglund P., et al. Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric mice. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 10332-10336
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 10332-10336
    • Hoglund, P.1
  • 18
    • 0030791728 scopus 로고    scopus 로고
    • Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene
    • Johansson M.H., et al. Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene. J. Exp. Med. 186 (1997) 353-364
    • (1997) J. Exp. Med. , vol.186 , pp. 353-364
    • Johansson, M.H.1
  • 19
    • 23644458333 scopus 로고    scopus 로고
    • Licensing of natural killer cells by host major histocompatibility complex class I molecules
    • Kim S., et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436 (2005) 709-713
    • (2005) Nature , vol.436 , pp. 709-713
    • Kim, S.1
  • 20
    • 18844365992 scopus 로고    scopus 로고
    • A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
    • Fernandez N.C., et al. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood 105 (2005) 4416-4423
    • (2005) Blood , vol.105 , pp. 4416-4423
    • Fernandez, N.C.1
  • 21
    • 49249086644 scopus 로고    scopus 로고
    • Continuous engagement of a self-specific activation receptor induces NK cell tolerance
    • Tripathy S.K., et al. Continuous engagement of a self-specific activation receptor induces NK cell tolerance. J. Exp. Med. 205 (2008) 1829-1841
    • (2008) J. Exp. Med. , vol.205 , pp. 1829-1841
    • Tripathy, S.K.1
  • 22
    • 58149343475 scopus 로고    scopus 로고
    • Beyond licensing and disarming: A quantitative view on NK-cell education
    • Brodin P., and Hoglund P. Beyond licensing and disarming: A quantitative view on NK-cell education. Eur. J. Immunol. 38 (2008) 2934-2937
    • (2008) Eur. J. Immunol. , vol.38 , pp. 2934-2937
    • Brodin, P.1    Hoglund, P.2
  • 23
    • 63849099445 scopus 로고    scopus 로고
    • The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells
    • 10.1182/blood-2008-05-156836
    • Brodin P., et al. The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells. Blood (2008) 10.1182/blood-2008-05-156836
    • (2008) Blood
    • Brodin, P.1
  • 24
    • 33750707891 scopus 로고    scopus 로고
    • Regulation of class I major histocompatibility complex receptor expression in natural killer cells: one promoter is not enough!
    • Pascal V., et al. Regulation of class I major histocompatibility complex receptor expression in natural killer cells: one promoter is not enough!. Immunol. Rev. 214 (2006) 9-21
    • (2006) Immunol. Rev. , vol.214 , pp. 9-21
    • Pascal, V.1
  • 25
    • 0033166539 scopus 로고    scopus 로고
    • Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors
    • Hanke T., et al. Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 11 (1999) 67-77
    • (1999) Immunity , vol.11 , pp. 67-77
    • Hanke, T.1
  • 26
    • 0026628008 scopus 로고
    • MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells
    • Karlhofer F.M., et al. MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells. Nature 358 (1992) 66-70
    • (1992) Nature , vol.358 , pp. 66-70
    • Karlhofer, F.M.1
  • 27
    • 33846551986 scopus 로고    scopus 로고
    • Interactions of Ly49 family receptors with MHC class I ligands in trans and cis
    • Scarpellino L., et al. Interactions of Ly49 family receptors with MHC class I ligands in trans and cis. J. Immunol. 178 (2007) 1277-1284
    • (2007) J. Immunol. , vol.178 , pp. 1277-1284
    • Scarpellino, L.1
  • 28
    • 0343340433 scopus 로고    scopus 로고
    • Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers
    • Michaelsson J., et al. Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers. Eur. J. Immunol. 30 (2000) 300-307
    • (2000) Eur. J. Immunol. , vol.30 , pp. 300-307
    • Michaelsson, J.1
  • 29
    • 49249089100 scopus 로고    scopus 로고
    • Regulation of NK cell responsiveness to achieve self-tolerance and maximal responses to diseased target cells
    • Joncker N.T., and Raulet D.H. Regulation of NK cell responsiveness to achieve self-tolerance and maximal responses to diseased target cells. Immunol. Rev. 224 (2008) 85-97
    • (2008) Immunol. Rev. , vol.224 , pp. 85-97
    • Joncker, N.T.1    Raulet, D.H.2
  • 30
    • 38449091911 scopus 로고    scopus 로고
    • Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands
    • Yu J., et al. Hierarchy of the human natural killer cell response is determined by class and quantity of inhibitory receptors for self-HLA-B and HLA-C ligands. J. Immunol. 179 (2007) 5977-5989
    • (2007) J. Immunol. , vol.179 , pp. 5977-5989
    • Yu, J.1
  • 31
    • 55249092534 scopus 로고    scopus 로고
    • MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response
    • Yawata M., et al. MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response. Blood 112 (2008) 2369-2380
    • (2008) Blood , vol.112 , pp. 2369-2380
    • Yawata, M.1
  • 32
    • 40549084319 scopus 로고    scopus 로고
    • Distinct KIR/HLA compound genotypes affect the kinetics of human antiviral natural killer cell responses
    • Ahlenstiel G., et al. Distinct KIR/HLA compound genotypes affect the kinetics of human antiviral natural killer cell responses. J. Clin. Invest. 118 (2008) 1017-1026
    • (2008) J. Clin. Invest. , vol.118 , pp. 1017-1026
    • Ahlenstiel, G.1
  • 33
    • 34249802335 scopus 로고    scopus 로고
    • Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1
    • Martin M.P., et al. Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat. Genet. 39 (2007) 733-740
    • (2007) Nat. Genet. , vol.39 , pp. 733-740
    • Martin, M.P.1
  • 34
    • 36549019907 scopus 로고    scopus 로고
    • Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes
    • Alter G., et al. Differential natural killer cell-mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes. J. Exp. Med. 204 (2007) 3027-3036
    • (2007) J. Exp. Med. , vol.204 , pp. 3027-3036
    • Alter, G.1
  • 35
    • 41149096579 scopus 로고    scopus 로고
    • T-cell quality in memory and protection: implications for vaccine design
    • Seder R.A., et al. T-cell quality in memory and protection: implications for vaccine design. Nat. Rev. Immunol. 8 (2008) 247-258
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 247-258
    • Seder, R.A.1
  • 36
    • 0031569268 scopus 로고    scopus 로고
    • Mouse natural killer subsets defined by their target specificity and their ability to be separately rendered unresponsive in vivo
    • Kung S.K., and Miller R.G. Mouse natural killer subsets defined by their target specificity and their ability to be separately rendered unresponsive in vivo. J. Immunol. 158 (1997) 2616-2626
    • (1997) J. Immunol. , vol.158 , pp. 2616-2626
    • Kung, S.K.1    Miller, R.G.2
  • 37
    • 0026443849 scopus 로고
    • Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses
    • Grossman Z., and Paul W.E. Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 10365-10369
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 10365-10369
    • Grossman, Z.1    Paul, W.E.2
  • 38
    • 0035546126 scopus 로고    scopus 로고
    • Autoreactivity, dynamic tuning and selectivity
    • Grossman Z., and Paul W.E. Autoreactivity, dynamic tuning and selectivity. Curr. Opin. Immunol. 13 (2001) 687-698
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 687-698
    • Grossman, Z.1    Paul, W.E.2
  • 39
    • 0041534399 scopus 로고    scopus 로고
    • Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity
    • Stebbins C.C., et al. Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity. Mol. Cell. Biol. 23 (2003) 6291-6299
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 6291-6299
    • Stebbins, C.C.1
  • 40
    • 53349164086 scopus 로고    scopus 로고
    • Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk
    • Peterson M.E., and Long E.O. Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk. Immunity 29 (2008) 578-588
    • (2008) Immunity , vol.29 , pp. 578-588
    • Peterson, M.E.1    Long, E.O.2
  • 41
    • 0035347262 scopus 로고    scopus 로고
    • Rap1 signalling: adhering to new models
    • Bos J.L., et al. Rap1 signalling: adhering to new models. Nat. Rev. Mol. Cell Biol. 2 (2001) 369-377
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 369-377
    • Bos, J.L.1
  • 42
    • 0030812812 scopus 로고    scopus 로고
    • Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1
    • Boussiotis V.A., et al. Maintenance of human T cell anergy: blocking of IL-2 gene transcription by activated Rap1. Science 278 (1997) 124-128
    • (1997) Science , vol.278 , pp. 124-128
    • Boussiotis, V.A.1
  • 43
    • 0033756553 scopus 로고    scopus 로고
    • CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1
    • Carey K.D., et al. CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1. Mol. Cell. Biol. 20 (2000) 8409-8419
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8409-8419
    • Carey, K.D.1
  • 44
    • 33947721625 scopus 로고    scopus 로고
    • miR-181a is an intrinsic modulator of T cell sensitivity and selection
    • Li Q.J., et al. miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129 (2007) 147-161
    • (2007) Cell , vol.129 , pp. 147-161
    • Li, Q.J.1
  • 45
    • 0037340163 scopus 로고    scopus 로고
    • Tuning the immune system: competing positive and negative feedback loops
    • Mueller D.L. Tuning the immune system: competing positive and negative feedback loops. Nat. Immunol. 4 (2003) 210-211
    • (2003) Nat. Immunol. , vol.4 , pp. 210-211
    • Mueller, D.L.1
  • 46
    • 0037338890 scopus 로고    scopus 로고
    • TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
    • Stefanova I., et al. TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways. Nat. Immunol. 4 (2003) 248-254
    • (2003) Nat. Immunol. , vol.4 , pp. 248-254
    • Stefanova, I.1
  • 47
    • 2442438499 scopus 로고    scopus 로고
    • Concomitant regulation of T-cell activation and homeostasis
    • Grossman Z., et al. Concomitant regulation of T-cell activation and homeostasis. Nat. Rev. Immunol. 4 (2004) 387-395
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 387-395
    • Grossman, Z.1
  • 48
    • 34247100277 scopus 로고    scopus 로고
    • Dendritic cells prime natural killer cells by trans-presenting interleukin 15
    • Lucas M., et al. Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity 26 (2007) 503-517
    • (2007) Immunity , vol.26 , pp. 503-517
    • Lucas, M.1


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