메뉴 건너뛰기




Volumn 5, Issue , 2014, Pages

Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR MARKER; BIOLOGICAL MARKER;

EID: 84907323440     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5684     Document Type: Article
Times cited : (139)

References (62)
  • 1
    • 84859154379 scopus 로고    scopus 로고
    • Beyond PSA: The next generation of prostate cancer biomarkers
    • Prensner, J. R., Rubin, M. A., Wei, J. T. & Chinnaiyan, A. M. Beyond PSA: the next generation of prostate cancer biomarkers. Sci. Trans. Med. 4, 127rv123 (2012).
    • (2012) Sci. Trans. Med. , vol.4 , pp. 127-123
    • Prensner, J.R.1    Rubin, M.A.2    Wei, J.T.3    Chinnaiyan, A.M.4
  • 2
    • 64649101697 scopus 로고    scopus 로고
    • CA125 in ovarian cancer
    • Scholler, N. & Urban, N. CA125 in ovarian cancer. Biomark. Med. 1, 513-523 (2007).
    • (2007) Biomark. Med. , vol.1 , pp. 513-523
    • Scholler, N.1    Urban, N.2
  • 3
    • 78449267111 scopus 로고    scopus 로고
    • The effects of adalimumab and methotrexate treatment on peripheral Th17 cells and IL-17/IL-6 secretion in rheumatoid arthritis patients
    • Yue, C. et al. The effects of adalimumab and methotrexate treatment on peripheral Th17 cells and IL-17/IL-6 secretion in rheumatoid arthritis patients. Rheumatol. Int. 30, 1553-1557 (2010).
    • (2010) Rheumatol. Int. , vol.30 , pp. 1553-1557
    • Yue, C.1
  • 4
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 84856544369 scopus 로고    scopus 로고
    • Translational genomics: The challenge of developing cancer biomarkers
    • Brooks, J. D. Translational genomics: The challenge of developing cancer biomarkers. Genome Res. 22, 183-187 (2012).
    • (2012) Genome Res. , vol.22 , pp. 183-187
    • Brooks, J.D.1
  • 7
    • 79956322553 scopus 로고    scopus 로고
    • Global quantification of mammalian gene expression control
    • Schwanhausser, B. et al. Global quantification of mammalian gene expression control. Nature 473, 337-342 (2011).
    • (2011) Nature , vol.473 , pp. 337-342
    • Schwanhausser, B.1
  • 8
    • 84875238998 scopus 로고    scopus 로고
    • Identification of genetic variants influencing the human plasma proteome
    • Johansson, A. et al. Identification of genetic variants influencing the human plasma proteome. Proc. Natl Acad. Sci. USA 110, 4673-4678 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 4673-4678
    • Johansson, A.1
  • 9
    • 80055072549 scopus 로고    scopus 로고
    • Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood
    • Lundberg, M., Eriksson, A., Tran, B., Assarsson, E. & Fredriksson, S. Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood. Nucleic Acids Res. 39, e102 (2011).
    • (2011) Nucleic Acids Res. , vol.39
    • Lundberg, M.1    Eriksson, A.2    Tran, B.3    Assarsson, E.4    Fredriksson, S.5
  • 10
    • 84899698183 scopus 로고    scopus 로고
    • Homogenous 96-Plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability
    • Assarsson, E. et al. Homogenous 96-Plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability. PLoS ONE 9, e95192 (2014).
    • (2014) PLoS ONE , vol.9
    • Assarsson, E.1
  • 11
    • 44949201115 scopus 로고    scopus 로고
    • A genome-wide association study identifies protein quantitative trait loci (pQTLs)
    • Melzer, D. et al. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet. 4, e1000072 (2008).
    • (2008) PLoS Genet. , vol.4
    • Melzer, D.1
  • 12
    • 35649004498 scopus 로고    scopus 로고
    • Effect of freeze-thaw cycles on serum measurements of AFP, CEA, CA125 and CA19-9
    • Gao, Y. C., Yuan, Z. B., Yang, Y. D. & Lu, H. K. Effect of freeze-thaw cycles on serum measurements of AFP, CEA, CA125 and CA19-9. Scand. J. Clin. Lab. Invest. 67, 741-747 (2007).
    • (2007) Scand. J. Clin. Lab. Invest. , vol.67 , pp. 741-747
    • Gao, Y.C.1    Yuan, Z.B.2    Yang, Y.D.3    Lu, H.K.4
  • 13
    • 84897538815 scopus 로고    scopus 로고
    • Smoke related DNA methylation changes in the etiology of human disease
    • Besingi, W. & Johansson, A. Smoke related DNA methylation changes in the etiology of human disease. Hum. Mol. Genet. 23, 2290-2297 (2014).
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 2290-2297
    • Besingi, W.1    Johansson, A.2
  • 14
    • 84856097166 scopus 로고    scopus 로고
    • Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1 soluble P-selectin and soluble E-selectin a meta-analysis
    • Kiechl, S. et al. Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin a meta-analysis. Circ. Cardiovasc. Gene 4, 681-U436 (2011).
    • (2011) Circ. Cardiovasc. Gene , vol.4
    • Kiechl, S.1
  • 15
    • 77952510546 scopus 로고    scopus 로고
    • Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes
    • Qi, L. et al. Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes. Hum. Mol. Genet. 19, 1856-1862 (2010).
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 1856-1862
    • Qi, L.1
  • 16
    • 77952595684 scopus 로고    scopus 로고
    • Expression of VEGF-C and VEGF-D as significant markers for assessment of lymphangiogenesis and lymph node metastasis in non-small cell lung cancer
    • Feng, Y. et al. Expression of VEGF-C and VEGF-D as significant markers for assessment of lymphangiogenesis and lymph node metastasis in non-small cell lung cancer. Anat. Rec. 293, 802-812 (2010).
    • (2010) Anat. Rec. , vol.293 , pp. 802-812
    • Feng, Y.1
  • 18
    • 83655197047 scopus 로고    scopus 로고
    • Human epididymis protein 4 reference limits and natural variation in a Nordic reference population
    • Bolstad, N., Oijordsbakken, M., Nustad, K. & Bjerner, J. Human epididymis protein 4 reference limits and natural variation in a Nordic reference population. Tumour Biol. 33, 141-148 (2012).
    • (2012) Tumour Biol. , vol.33 , pp. 141-148
    • Bolstad, N.1    Oijordsbakken, M.2    Nustad, K.3    Bjerner, J.4
  • 19
    • 84871410405 scopus 로고    scopus 로고
    • The evolutionary landscape of alternative splicing in vertebrate species
    • Barbosa-Morais, N. L. et al. The evolutionary landscape of alternative splicing in vertebrate species. Science 338, 1587-1593 (2012).
    • (2012) Science , vol.338 , pp. 1587-1593
    • Barbosa-Morais, N.L.1
  • 20
    • 84865727393 scopus 로고    scopus 로고
    • The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
    • Derrien, T. et al. The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res. 22, 1775-1789 (2012).
    • (2012) Genome Res. , vol.22 , pp. 1775-1789
    • Derrien, T.1
  • 21
    • 84860117771 scopus 로고    scopus 로고
    • Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer
    • Asmann, Y. W. et al. Detection of redundant fusion transcripts as biomarkers or disease-specific therapeutic targets in breast cancer. Cancer Res. 72, 1921-1928 (2012).
    • (2012) Cancer Res. , vol.72 , pp. 1921-1928
    • Asmann, Y.W.1
  • 22
    • 84882392732 scopus 로고    scopus 로고
    • A functional genomic perspective on human well-being
    • Fredrickson, B. L. et al. A functional genomic perspective on human well-being. Proc. Natl Acad. Sci. USA 110, 13684-13689 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 13684-13689
    • Fredrickson, B.L.1
  • 23
    • 45149108420 scopus 로고    scopus 로고
    • Mapping the genetic architecture of gene expression in human liver
    • Schadt, E. E. et al. Mapping the genetic architecture of gene expression in human liver. PLoS Biol. 6, e107 (2008).
    • (2008) PLoS Biol. , vol.6
    • Schadt, E.E.1
  • 25
    • 84856397883 scopus 로고    scopus 로고
    • Enhanced levels of CCL19 in patients with advanced acquired immune deficiency syndrome (AIDS)
    • Damas, J. K. et al. Enhanced levels of CCL19 in patients with advanced acquired immune deficiency syndrome (AIDS). Clin. Exp. Immunol. 167, 492-498 (2012).
    • (2012) Clin. Exp. Immunol. , vol.167 , pp. 492-498
    • Damas, J.K.1
  • 26
    • 48249091698 scopus 로고    scopus 로고
    • Novel association of ABO histo-blood group antigen with soluble ICAM-1: Results of a genome-wide association study of 6, 578 women
    • Pare, G. et al. Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6, 578 women. PLoS Genet. 4, e1000118 (2008).
    • (2008) PLoS Genet. , vol.4
    • Pare, G.1
  • 27
    • 84891738394 scopus 로고    scopus 로고
    • Chemokine (C-X-C motif) ligand (CXCL)10 in autoimmune diseases
    • Antonelli, A. et al. Chemokine (C-X-C motif) ligand (CXCL)10 in autoimmune diseases. Autoimmun. Rev. 13, 272-280 (2014).
    • (2014) Autoimmun. Rev. , vol.13 , pp. 272-280
    • Antonelli, A.1
  • 28
    • 84863704124 scopus 로고    scopus 로고
    • High serum levels of CXC (CXCL10) and CC (CCL2) chemokines in untreated essential hypertension
    • Antonelli, A. et al. High serum levels of CXC (CXCL10) and CC (CCL2) chemokines in untreated essential hypertension. Int. J. Immunopathol. Pharmacol. 25, 387-395 (2012).
    • (2012) Int. J. Immunopathol. Pharmacol. , vol.25 , pp. 387-395
    • Antonelli, A.1
  • 29
    • 66749098111 scopus 로고    scopus 로고
    • WHO
    • WHO. Fact sheet No 297 (http://www.who.int/mediacentre/factsheets/fs297/ en/) (2013).
    • (2013) Fact Sheet No 297
  • 30
    • 84864868843 scopus 로고    scopus 로고
    • EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer
    • Boye, K. et al. EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer. Br. J. Cancer 107, 667-674 (2012).
    • (2012) Br. J. Cancer , vol.107 , pp. 667-674
    • Boye, K.1
  • 31
    • 79957673711 scopus 로고    scopus 로고
    • IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer
    • Neurath, M. F. & Finotto, S. IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer. Cytokine Growth Factor Rev. 22, 83-89 (2011).
    • (2011) Cytokine Growth Factor Rev. , vol.22 , pp. 83-89
    • Neurath, M.F.1    Finotto, S.2
  • 32
    • 84875687447 scopus 로고    scopus 로고
    • Biologic therapy for autoimmune diseases: An update
    • Rosman, Z., Shoenfeld, Y. & Zandman-Goddard, G. Biologic therapy for autoimmune diseases: an update. BMC Med. 11, 88 (2013).
    • (2013) BMC Med. , vol.11 , pp. 88
    • Rosman, Z.1    Shoenfeld, Y.2    Zandman-Goddard, G.3
  • 33
    • 84890957085 scopus 로고    scopus 로고
    • Predictors of response and remission in a large cohort of rheumatoid arthritis patients treated with tocilizumab in clinical practice
    • Pers, Y. M. et al. Predictors of response and remission in a large cohort of rheumatoid arthritis patients treated with tocilizumab in clinical practice. Rheumatology 53, 76-84 (2014).
    • (2014) Rheumatology , vol.53 , pp. 76-84
    • Pers, Y.M.1
  • 35
    • 84881260633 scopus 로고    scopus 로고
    • Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis
    • Zhao, S. X. et al. Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. Hum. Mol. Genet. 22, 3347-3362 (2013).
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 3347-3362
    • Zhao, S.X.1
  • 36
    • 80052260527 scopus 로고    scopus 로고
    • A genome-wide association study identifies two new risk loci for Graves' disease
    • Chu, X. et al. A genome-wide association study identifies two new risk loci for Graves' disease. Nat. Genet. 43, 897-901 (2011).
    • (2011) Nat. Genet. , vol.43 , pp. 897-901
    • Chu, X.1
  • 38
    • 84893586947 scopus 로고    scopus 로고
    • Current approaches and challenges in managing and monitoring treatment response in ovarian cancer
    • Marcus, C. S., Maxwell, G. L., Darcy, K. M., Hamilton, C. A. & McGuire, W. P. Current approaches and challenges in managing and monitoring treatment response in ovarian cancer. J. Cancer 5, 25-30 (2014).
    • (2014) J. Cancer , vol.5 , pp. 25-30
    • Marcus, C.S.1    Maxwell, G.L.2    Darcy, K.M.3    Hamilton, C.A.4    McGuire, W.P.5
  • 39
    • 77949262349 scopus 로고    scopus 로고
    • Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma
    • Takayama, R. et al. Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma. J. Gastroenterol. 45, 52-59 (2010).
    • (2010) J. Gastroenterol. , vol.45 , pp. 52-59
    • Takayama, R.1
  • 40
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • Lango Allen, H. et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 467, 832-838 (2010).
    • (2010) Nature , vol.467 , pp. 832-838
    • Lango Allen, H.1
  • 41
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1
  • 43
    • 79952395270 scopus 로고    scopus 로고
    • Cancer genomics: From discovery science to personalized medicine
    • Chin, L., Andersen, J. N. & Futreal, P. A. Cancer genomics: from discovery science to personalized medicine. Nat. Med. 17, 297-303 (2011).
    • (2011) Nat. Med. , vol.17 , pp. 297-303
    • Chin, L.1    Andersen, J.N.2    Futreal, P.A.3
  • 44
    • 58049206782 scopus 로고    scopus 로고
    • Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis
    • Johansson, A. et al. Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis. Hum. Mol. Genet. 18, 373-380 (2009).
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 373-380
    • Johansson, A.1
  • 45
    • 77957274046 scopus 로고    scopus 로고
    • The Northern Swedish Population Health Study (NSPHS)-A paradigmatic study in a rural population combining community health and basic research
    • Igl, W., Johansson, A. & Gyllensten, U. The Northern Swedish Population Health Study (NSPHS)-a paradigmatic study in a rural population combining community health and basic research. Rural Remote Health 10, 1363 (2010).
    • (2010) Rural Remote Health , vol.10 , pp. 1363
    • Igl, W.1    Johansson, A.2    Gyllensten, U.3
  • 46
    • 84881290653 scopus 로고    scopus 로고
    • Prevalence and sensitization of atopic allergy and coeliac disease in the Northern Sweden Population Health Study
    • Enroth, S., Dahlbom, I., Hansson, T., Johansson, A. & Gyllensten, U. Prevalence and sensitization of atopic allergy and coeliac disease in the Northern Sweden Population Health Study. Int. J. Circumpolar Health 72 (2013).
    • (2013) Int. J. Circumpolar Health , vol.72
    • Enroth, S.1    Dahlbom, I.2    Hansson, T.3    Johansson, A.4    Gyllensten, U.5
  • 47
    • 84881307062 scopus 로고    scopus 로고
    • Animal source food intake and association with blood cholesterol, glycerophospholipids and sphingolipids in a northern Swedish population
    • Igl, W. et al. Animal source food intake and association with blood cholesterol, glycerophospholipids and sphingolipids in a northern Swedish population. Int. J. Circumpolar. Health 72 (2013).
    • (2013) Int. J. Circumpolar. Health , vol.72
    • Igl, W.1
  • 48
    • 0034694856 scopus 로고    scopus 로고
    • Ethical principles for medical research involving human subjects
    • World Medical Association Declaration of Helsinki:
    • World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA 284, 3043-3045 (2000).
    • (2000) JAMA , vol.284 , pp. 3043-3045
  • 49
    • 77149153374 scopus 로고    scopus 로고
    • Comparison of participant information and informed consent forms of five European studies in genetic isolated populations
    • Mascalzoni, D. et al. Comparison of participant information and informed consent forms of five European studies in genetic isolated populations. Eur. J. Hum. Genet. 18, 296-302 (2010).
    • (2010) Eur. J. Hum. Genet. , vol.18 , pp. 296-302
    • Mascalzoni, D.1
  • 50
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575
    • Am. J. Hum. Genet. , vol.81 , pp. 559-575
    • Purcell, S.1
  • 51
    • 84884587140 scopus 로고    scopus 로고
    • Inference of identity by descent in population isolates and optimal sequencing studies
    • Glodzik, D. et al. Inference of identity by descent in population isolates and optimal sequencing studies. Eur. J. Hum. Genet. 21, 1140-1145 (2013).
    • (2013) Eur. J. Hum. Genet. , vol.21 , pp. 1140-1145
    • Glodzik, D.1
  • 52
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from populationscale sequencing
    • Genomes Project, C. et al. A map of human genome variation from populationscale sequencing. Nature 467, 1061-1073 (2010).
    • (2010) Nature , vol.467 , pp. 1061-1073
    • Genomes Project, C.1
  • 53
    • 85067760368 scopus 로고    scopus 로고
    • IMPUTE2
    • IMPUTE2 (https://mathgen.stats.ox.ac.uk/impute/impute-v2.html#reference) (2012).
    • (2012)
  • 54
    • 84871952176 scopus 로고    scopus 로고
    • Improved whole-chromosome phasing for disease and population genetic studies
    • Delaneau, O., Zagury, J. F. & Marchini, J. Improved whole-chromosome phasing for disease and population genetic studies. Nat. Methods 10, 5-6 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 5-6
    • Delaneau, O.1    Zagury, J.F.2    Marchini, J.3
  • 55
    • 84864417548 scopus 로고    scopus 로고
    • Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
    • Howie, B., Fuchsberger, C., Stephens, M., Marchini, J. & Abecasis, G. R. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat. Genet. 44, 955-959 (2012).
    • (2012) Nat. Genet. , vol.44 , pp. 955-959
    • Howie, B.1    Fuchsberger, C.2    Stephens, M.3    Marchini, J.4    Abecasis, G.R.5
  • 56
    • 84907339630 scopus 로고    scopus 로고
    • Freeman, C. & Marchini, J. GTOOL (http://www.well.ox.ac.uk/Bcfreeman/ software/gwas/gtool.html) (2013).
    • (2013) GTOOL
    • Freeman, C.1    Marchini, J.2
  • 58
    • 78650323492 scopus 로고    scopus 로고
    • Variant ABO blood group alleles, secretor status, and risk of pancreatic cancer: Results from the pancreatic cancer cohort consortium
    • Wolpin, B. M. et al. Variant ABO blood group alleles, secretor status, and risk of pancreatic cancer: results from the pancreatic cancer cohort consortium. Cancer Epidemiol Biomark. Prevent. 19, 3140-3149 (2010).
    • (2010) Cancer Epidemiol Biomark. Prevent. , vol.19 , pp. 3140-3149
    • Wolpin, B.M.1
  • 60
    • 69649109364 scopus 로고    scopus 로고
    • Circos: An information aesthetic for comparative genomics
    • Krzywinski, M. et al. Circos: an information aesthetic for comparative genomics. Genome Res. 19, 1639-1645 (2009).
    • (2009) Genome Res. , vol.19 , pp. 1639-1645
    • Krzywinski, M.1
  • 61
    • 34447324105 scopus 로고    scopus 로고
    • GenABEL: An R library for genome-wide association analysis
    • DOI 10.1093/bioinformatics/btm108
    • Aulchenko, Y. S., Ripke, S., Isaacs, A. & Van Duijn, C. M. GenABEL: an R library for genome-wide association analysis. Bioinformatics. 23, 1294-1296 (2007). (Pubitemid 47050548)
    • (2007) Bioinformatics , vol.23 , Issue.10 , pp. 1294-1296
    • Aulchenko, Y.S.1    Ripke, S.2    Isaacs, A.3    Van Duijn, C.M.4
  • 62
    • 34547628858 scopus 로고    scopus 로고
    • Family-based association tests for genomewide association scans
    • DOI 10.1086/521580
    • Chen, W. M. & Abecasis, G. R. Family-based association tests for genomewide association scans. Am. J. Hum. Genet. 81, 913-926 (2007). (Pubitemid 47580246)
    • (2007) American Journal of Human Genetics , vol.81 , Issue.5 , pp. 913-926
    • Chen, W.-M.1    Abecasis, G.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.