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Volumn 26, Issue 2, 2017, Pages 91-96

Update on angiotensin AT2 receptors

Author keywords

angiotensin; angiotensin receptors; blood pressure; hypertension; kidney function; kidney protection; natriuresis; sodium excretion

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN III; NITRIC OXIDE; SODIUM;

EID: 85000925662     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/MNH.0000000000000304     Document Type: Review
Times cited : (45)

References (51)
  • 1
    • 0037667643 scopus 로고    scopus 로고
    • Newly recognized components of the renin-angio-tensin system: Potential roles in cardiovascular and renal regulation
    • Carey RM, Siragy HM. Newly recognized components of the renin-angio-tensin system: potential roles in cardiovascular and renal regulation. Endocr Rev 2003; 24:261-271.
    • (2003) Endocr Rev , vol.24 , pp. 261-271
    • Carey, R.M.1    Siragy, H.M.2
  • 2
    • 84886406732 scopus 로고    scopus 로고
    • Newly discovered components and actions of the renin-angio-tensin system
    • Carey RM. Newly discovered components and actions of the renin-angio-tensin system. Hypertension 2013; 62:818-822.
    • (2013) Hypertension , vol.62 , pp. 818-822
    • Carey, R.M.1
  • 3
    • 0030722325 scopus 로고    scopus 로고
    • Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney
    • Ozono R, Wang Z-Q, Moore AF, et al. Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney. Hypertension 1997; 30:1238-1246.
    • (1997) Hypertension , vol.30 , pp. 1238-1246
    • Ozono, R.1    Wang, Z.-Q.2    Moore, A.F.3
  • 4
    • 0033194720 scopus 로고    scopus 로고
    • Distribution of angiotensin AT1 and AT2 receptor subtypes in the rat kidney
    • Miyata N, Park F, Li XF, Cowley AW Jr. Distribution of angiotensin AT1 and AT2 receptor subtypes in the rat kidney. Am J Physiol Renal Physiol 1999; 277:F437-F446.
    • (1999) Am J Physiol Renal Physiol , vol.277 , pp. F437-F446
    • Miyata, N.1    Park, F.2    Li, X.F.3    Cowley, A.W.4
  • 5
    • 0032990242 scopus 로고    scopus 로고
    • Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 (AT2) angiotensin receptor
    • Siragy HM, Inagami T, Ichiki T, Carey RM. Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 (AT2) angiotensin receptor. Proc Natl Acad Sci U S A 1999; 96:6506-6510.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6506-6510
    • Siragy, H.M.1    Inagami, T.2    Ichiki, T.3    Carey, R.M.4
  • 6
    • 0033999935 scopus 로고    scopus 로고
    • Inhibition of pressure natriuresis in mice lacking the AT2 receptor
    • Gross V, Schunck WH, Honeck H, et al. Inhibition of pressure natriuresis in mice lacking the AT2 receptor. Kidney Int 2000; 57:191-202.
    • (2000) Kidney Int , vol.57 , pp. 191-202
    • Gross, V.1    Schunck, W.H.2    Honeck, H.3
  • 7
    • 0037304643 scopus 로고    scopus 로고
    • Pressure natriuresis in AT2 receptor-deficient mice with L-NAME hypertension
    • Obst M, Gross V, Janke J, et al. Pressure natriuresis in AT2 receptor-deficient mice with L-NAME hypertension. J Am Soc Nephrol 2003; 14:303-310.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 303-310
    • Obst, M.1    Gross, V.2    Janke, J.3
  • 8
    • 33644987169 scopus 로고    scopus 로고
    • Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat
    • Padia SH, Howell NL, Siragy HM, Carey RM. Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat. Hypertension 2006; 47:537-544.
    • (2006) Hypertension , vol.47 , pp. 537-544
    • Padia, S.H.1    Howell, N.L.2    Siragy, H.M.3    Carey, R.M.4
  • 9
    • 33847049473 scopus 로고    scopus 로고
    • Intrarenal aminopeptidase N inhibition augments natriuretic responses to angiotensin III in angiotensin type 1 receptor-blocked rats
    • Padia SH, Kemp BA, Howell NL, et al. Intrarenal aminopeptidase N inhibition augments natriuretic responses to angiotensin III in angiotensin type 1 receptor-blocked rats. Hypertension 2007; 49:625-630.
    • (2007) Hypertension , vol.49 , pp. 625-630
    • Padia, S.H.1    Kemp, B.A.2    Howell, N.L.3
  • 10
    • 38549150268 scopus 로고    scopus 로고
    • Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats
    • Padia SH, Kemp BA, Howell NL, et al. Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats. Hypertension 2008; 51:460-465.
    • (2008) Hypertension , vol.51 , pp. 460-465
    • Padia, S.H.1    Kemp, B.A.2    Howell, N.L.3
  • 11
    • 13144305024 scopus 로고    scopus 로고
    • Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats
    • Hakam AC, Hussain T. Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats. Hypertension 2005; 45:270-275.
    • (2005) Hypertension , vol.45 , pp. 270-275
    • Hakam, A.C.1    Hussain, T.2
  • 12
    • 33644853444 scopus 로고    scopus 로고
    • Renal angiotensin II AT2 receptors promote natriuresis in streptozotocin-induced diabetic rats
    • Hakam AC, Siddiqui AH, Hussain T. Renal angiotensin II AT2 receptors promote natriuresis in streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol 2006; 290:F503-F508.
    • (2006) Am J Physiol Renal Physiol , vol.290 , pp. F503-F508
    • Hakam, A.C.1    Siddiqui, A.H.2    Hussain, T.3
  • 13
    • 33744791745 scopus 로고    scopus 로고
    • Angiotensin II AT2 receptors inhibit proximal tubular Na+K+ATPase activity via a NO/cGMP-dependent pathway
    • Hakam AC, Hussain T. Angiotensin II AT2 receptors inhibit proximal tubular Na+K+ATPase activity via a NO/cGMP-dependent pathway. Am J Physiol Renal Physiol 2006; 290:F1430-F1436.
    • (2006) Am J Physiol Renal Physiol , vol.290 , pp. F1430-F1436
    • Hakam, A.C.1    Hussain, T.2
  • 14
    • 33744985044 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not lean Zucker rats
    • Hakam AC, Hussain T. Angiotensin type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not lean Zucker rats. Hypertension 2006; 47:1117-1124.
    • (2006) Hypertension , vol.47 , pp. 1117-1124
    • Hakam, A.C.1    Hussain, T.2
  • 15
    • 84861847267 scopus 로고    scopus 로고
    • AT2 receptor non-peptide agonist C21 promotes natriuresis in obese Zucker rats
    • Ali Q, Hussain T. AT2 receptor non-peptide agonist C21 promotes natriuresis in obese Zucker rats. Hypertens Res 2012; 35:654-660.
    • (2012) Hypertens Res , vol.35 , pp. 654-660
    • Ali, Q.1    Hussain, T.2
  • 16
    • 84864276934 scopus 로고    scopus 로고
    • Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors
    • Kemp BA, Bell JF, Rottkamp DM, et al. Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors. Hypertension 2012; 60:387-395.
    • (2012) Hypertension , vol.60 , pp. 387-395
    • Kemp, B.A.1    Bell, J.F.2    Rottkamp, D.M.3
  • 17
    • 0347020888 scopus 로고
    • Stimulation of renal sodium reabsorption by angio-tensin II
    • Johnson MD, Malvin RL. Stimulation of renal sodium reabsorption by angio-tensin II. Am J Physiol 1977; 232:F298-F306.
    • (1977) Am J Physiol , vol.232 , pp. F298-F306
    • Johnson, M.D.1    Malvin, R.L.2
  • 18
    • 0028345602 scopus 로고
    • Altered pressure natriuresis in chronic angiotensin II hypertension in rats
    • van der Mark J, Kline RL. Altered pressure natriuresis in chronic angiotensin II hypertension in rats. Am J Physiol 1994; 266:R739-R748.
    • (1994) Am J Physiol , vol.266 , pp. R739-R748
    • Van Der Mark, J.1    Kline, R.L.2
  • 19
    • 0025823703 scopus 로고
    • Influence of angiotensin II on pressure natriuresis and renal hemodynamics in volume-expanded rats
    • Mattson DL, Raff H, Roman RJ. Influence of angiotensin II on pressure natriuresis and renal hemodynamics in volume-expanded rats. Am J Physiol 1991; 260:R1200-1209.
    • (1991) Am J Physiol , vol.260 , pp. R1200-R1209
    • Mattson, D.L.1    Raff, H.2    Roman, R.J.3
  • 20
    • 8644281991 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist
    • Wan Y, Wallinder C, Plouffe B. Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. J Med Chem 2004; 47:5995-6008.
    • (2004) J Med Chem , vol.47 , pp. 5995-6008
    • Wan, Y.1    Wallinder, C.2    Plouffe, B.3
  • 21
    • 80054084671 scopus 로고    scopus 로고
    • Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors
    • Bosnyak S, Jones ES, Christopoulos A, et al. Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors. Clin Sci (Lond) 2011; 121:297-303.
    • (2011) Clin Sci (Lond) , vol.121 , pp. 297-303
    • Bosnyak, S.1    Jones, E.S.2    Christopoulos, A.3
  • 22
    • 84904735782 scopus 로고    scopus 로고
    • AT2 receptor activation induces natriuresis and lowers blood pressure
    • Kemp BA, Howell NL, Gildea JJ, et al. AT2 receptor activation induces natriuresis and lowers blood pressure. Circ Res 2014; 115:388-399.
    • (2014) Circ Res , vol.115 , pp. 388-399
    • Kemp, B.A.1    Howell, N.L.2    Gildea, J.J.3
  • 23
    • 0029955002 scopus 로고    scopus 로고
    • Renin-angiotensin system modulates renal bradykinin production
    • Siragy HM, Jaffa AA, Margolius HS, Carey RM. Renin-angiotensin system modulates renal bradykinin production. Am J Physiol 1996; 271:R1090- R1095.
    • (1996) Am J Physiol , vol.271 , pp. R1090-R1095
    • Siragy, H.M.1    Jaffa, A.A.2    Margolius, H.S.3    Carey, R.M.4
  • 24
    • 0030610587 scopus 로고    scopus 로고
    • The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats
    • Siragy HM, Carey RM. The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats. J Clin Invest 1997; 100:264-269.
    • (1997) J Clin Invest , vol.100 , pp. 264-269
    • Siragy, H.M.1    Carey, R.M.2
  • 25
    • 84943604240 scopus 로고    scopus 로고
    • Enhanced natriuresis and diuresis in Wistar rats caused by the costimulation of renal dopamine D3 and angiotensin II type 2 receptors
    • Yang S, Han Y, Zheng S, et al. Enhanced natriuresis and diuresis in Wistar rats caused by the costimulation of renal dopamine D3 and angiotensin II type 2 receptors. Am J Hypertens 2015; 28:1267-1276.
    • (2015) Am J Hypertens , vol.28 , pp. 1267-1276
    • Yang, S.1    Han, Y.2    Zheng, S.3
  • 26
    • 33847615585 scopus 로고    scopus 로고
    • Intrarenal dopamine D1-like receptor stimulation induces natriuresis via an angiotensin type-2 receptor mechanism
    • Salomone LJ, Howell NL, McGrath HE, et al. Intrarenal dopamine D1-like receptor stimulation induces natriuresis via an angiotensin type-2 receptor mechanism. Hypertension 2007; 49:155-161.
    • (2007) Hypertension , vol.49 , pp. 155-161
    • Salomone, L.J.1    Howell, N.L.2    McGrath, H.E.3
  • 27
    • 84856114750 scopus 로고    scopus 로고
    • Mechanisms of dopamine D(1) and angiotensin type 2 receptor interaction in natriuresis
    • Padia SH, Kemp BA, Howell NL, et al. Mechanisms of dopamine D(1) and angiotensin type 2 receptor interaction in natriuresis. Hypertension 2012; 59:437-445.
    • (2012) Hypertension , vol.59 , pp. 437-445
    • Padia, S.H.1    Kemp, B.A.2    Howell, N.L.3
  • 28
    • 84978069608 scopus 로고    scopus 로고
    • AT2 receptor activation prevents sodium retention and reduces blood pressure in angiotensin II-dependent hypertension
    • Kemp BA, Howell NL, Keller SR, et al. AT2 receptor activation prevents sodium retention and reduces blood pressure in angiotensin II-dependent hypertension. Circ Res 2016; 119:532-543.
    • (2016) Circ Res , vol.119 , pp. 532-543
    • Kemp, B.A.1    Howell, N.L.2    Keller, S.R.3
  • 29
    • 84870523200 scopus 로고    scopus 로고
    • Impact of AT2 receptor agonist C21 on blood pressure and beyond
    • Fouiquier S, Steckelings UM, Unger T. Impact of AT2 receptor agonist C21 on blood pressure and beyond. Curr Hypertens Rep 2012; 14:403-409.
    • (2012) Curr Hypertens Rep , vol.14 , pp. 403-409
    • Fouiquier, S.1    Steckelings, U.M.2    Unger, T.3
  • 30
    • 84922560906 scopus 로고    scopus 로고
    • Angiotensin type 2 receptors: Blood pressure regulation and end organ damage
    • Sumners C, de Kloet AD, Krause EG, et al. Angiotensin type 2 receptors: blood pressure regulation and end organ damage. Curr Opin Pharmacol 2015; 21:115-121.
    • (2015) Curr Opin Pharmacol , vol.21 , pp. 115-121
    • Sumners, C.1    De Kloet, A.D.2    Krause, E.G.3
  • 31
    • 79953216990 scopus 로고    scopus 로고
    • A single beta-amino acid substitution to angiotensin II confers AT(2) receptor selectivity and vascular function
    • Jones ES, Del Borgo MP, Kirsch JF, et al. A single beta-amino acid substitution to angiotensin II confers AT(2) receptor selectivity and vascular function. Hypertension 2011; 57:570-576.
    • (2011) Hypertension , vol.57 , pp. 570-576
    • Jones, E.S.1    Del Borgo, M.P.2    Kirsch, J.F.3
  • 32
    • 0027208946 scopus 로고
    • Angiotensin type 2 receptors mediate depressor phase of biphasic pressure responses to angiotensin
    • Scheuer DA, Perrone MH. Angiotensin type 2 receptors mediate depressor phase of biphasic pressure responses to angiotensin. Am J Physiol 1993; 264:R917-R923.
    • (1993) Am J Physiol , vol.264 , pp. R917-R923
    • Scheuer, D.A.1    Perrone, M.H.2
  • 33
    • 84942809272 scopus 로고    scopus 로고
    • B-Pro7 Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats
    • Del Borgo M, Wang Y, Bosnyak S, et al. b-Pro7 Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats. Clin Sci 2015; 129:505-513.
    • (2015) Clin Sci , vol.129 , pp. 505-513
    • Del Borgo, M.1    Wang, Y.2    Bosnyak, S.3
  • 34
    • 56149096807 scopus 로고    scopus 로고
    • AT2 receptors: Functional relevance in cardiovascular disease
    • Jones ES, Vinh A, McCarthy CA, et al. AT2 receptors: functional relevance in cardiovascular disease. Pharmacol Ther 2008; 120:292-316.
    • (2008) Pharmacol Ther , vol.120 , pp. 292-316
    • Jones, E.S.1    Vinh, A.2    McCarthy, C.A.3
  • 35
    • 85003948299 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor (AT2R) in renal and cardiovascular disease
    • Chow BSM, Allen TJ. Angiotensin II type 2 receptor (AT2R) in renal and cardiovascular disease. Clin Sci (Lond) 2016; 130:1307-1326.
    • (2016) Clin Sci (Lond) , vol.130 , pp. 1307-1326
    • Chow, B.S.M.1    Allen, T.J.2
  • 36
    • 0141997228 scopus 로고    scopus 로고
    • Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice
    • Abadir PM, Carey RM, Siragy HM. Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice. Hypertension 2003; 42:600-604.
    • (2003) Hypertension , vol.42 , pp. 600-604
    • Abadir, P.M.1    Carey, R.M.2    Siragy, H.M.3
  • 37
    • 0035570466 scopus 로고    scopus 로고
    • Normal blood pressure and renal function in mice lacking the bradykinin B(2) receptor
    • Milia AF, Gross V, Piehm R, et al. Normal blood pressure and renal function in mice lacking the bradykinin B(2) receptor. Hypertension 2001; 37:1473-1479.
    • (2001) Hypertension , vol.37 , pp. 1473-1479
    • Milia, A.F.1    Gross, V.2    Piehm, R.3
  • 38
    • 84973522279 scopus 로고    scopus 로고
    • Nitric oxide up-regulates endothelial expression of angiotensin II type 2 receptors
    • Dao VT, Medini S, Bishna M, et al. Nitric oxide up-regulates endothelial expression of angiotensin II type 2 receptors. Biochem Pharmacol 2016; 112:24-36.
    • (2016) Biochem Pharmacol , vol.112 , pp. 24-36
    • Dao, V.T.1    Medini, S.2    Bishna, M.3
  • 39
    • 0033935114 scopus 로고    scopus 로고
    • The angiotensin type II receptor tonically inhibits angiotensin-converting enzyme in AT2 null mutant mice
    • Hunley TE, Tamura M, Stoneking BJ, et al. The angiotensin type II receptor tonically inhibits angiotensin-converting enzyme in AT2 null mutant mice. Kidney Int 2000; 57:570-577.
    • (2000) Kidney Int , vol.57 , pp. 570-577
    • Hunley, T.E.1    Tamura, M.2    Stoneking, B.J.3
  • 40
    • 0029808766 scopus 로고    scopus 로고
    • Hypertension in obese Zucker rats. Role of angiotensin II and adrenergic activity
    • Alonso-Galicia M, Brands MW, Zappe DH, Hall JE. Hypertension in obese Zucker rats. Role of angiotensin II and adrenergic activity. Hypertension 1996; 28:1047-1054.
    • (1996) Hypertension , vol.28 , pp. 1047-1054
    • Alonso-Galicia, M.1    Brands, M.W.2    Zappe, D.H.3    Hall, J.E.4
  • 41
    • 59849087336 scopus 로고    scopus 로고
    • Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats
    • Siddiqui AH, Ali Q, Hussain T. Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats. Hypertension 2009; 53:256-261.
    • (2009) Hypertension , vol.53 , pp. 256-261
    • Siddiqui, A.H.1    Ali, Q.2    Hussain, T.3
  • 42
    • 84888375977 scopus 로고    scopus 로고
    • Chronic AT2 receptor activation attenuates renal AT1 receptor function and blood pressure in obese Zucker rats
    • Ali Q, Wu Y, Hussain T. Chronic AT2 receptor activation attenuates renal AT1 receptor function and blood pressure in obese Zucker rats. Kidney Int 2013; 84:931-939.
    • (2013) Kidney Int , vol.84 , pp. 931-939
    • Ali, Q.1    Wu, Y.2    Hussain, T.3
  • 43
    • 84931098651 scopus 로고    scopus 로고
    • Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats
    • Ali Q, Patel S, Hussain T. Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol 2015; 308:F1379-F1385.
    • (2015) Am J Physiol Renal Physiol , vol.308 , pp. F1379-F1385
    • Ali, Q.1    Patel, S.2    Hussain, T.3
  • 44
    • 84864136742 scopus 로고    scopus 로고
    • Six commercially available angiotensin II AT2 receptor antibodies are non-specific
    • Benicky J, Hafko R, Sanchez-Lemus E, et al. Six commercially available angiotensin II AT2 receptor antibodies are non-specific. Cell Mol Neurobiol 2012; 32:1353-1365.
    • (2012) Cell Mol Neurobiol , vol.32 , pp. 1353-1365
    • Benicky, J.1    Hafko, R.2    Sanchez-Lemus, E.3
  • 45
    • 0031446688 scopus 로고    scopus 로고
    • Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: Evidence for selective sorting of receptor and ligand
    • Hein L, Meinel L, Pratt RE, et al. Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand. Mol Endocrinol 1997; 11:1266-1277.
    • (1997) Mol Endocrinol , vol.11 , pp. 1266-1277
    • Hein, L.1    Meinel, L.2    Pratt, R.E.3
  • 46
    • 0036771844 scopus 로고    scopus 로고
    • AT2 receptor-mediated relaxation is preserved after long-term AT1 receptor blockade
    • Widdop RE, Matrougui K, Levy BI, Henrion D. AT2 receptor-mediated relaxation is preserved after long-term AT1 receptor blockade. Hypertension 2002; 40:516-520.
    • (2002) Hypertension , vol.40 , pp. 516-520
    • Widdop, R.E.1    Matrougui, K.2    Levy, B.I.3    Henrion, D.4
  • 47
    • 0025811214 scopus 로고
    • Obese Zucker rat: Potential role of intraglomerular proteolytic enzymes in the development of glomerulo-sclerosis
    • Teschner M, Paczek L, Schaefer RM, Heidland A. Obese Zucker rat: potential role of intraglomerular proteolytic enzymes in the development of glomerulo-sclerosis. Res Exp Med (Berl) 1991; 191:129-135.
    • (1991) Res Exp Med (Berl) , vol.191 , pp. 129-135
    • Teschner, M.1    Paczek, L.2    Schaefer, R.M.3    Heidland, A.4
  • 48
    • 84856120678 scopus 로고    scopus 로고
    • Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats
    • Rehman A, Leibowitz A, Yamamoto N, et al. Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension 2012; 59:291-299.
    • (2012) Hypertension , vol.59 , pp. 291-299
    • Rehman, A.1    Leibowitz, A.2    Yamamoto, N.3
  • 49
    • 84925466903 scopus 로고    scopus 로고
    • AT2 receptor activities and pathophysiological implications
    • Matavelli LC, Siragy HM. AT2 receptor activities and pathophysiological implications. J Cardiovasc Pharmacol 2015; 65:226-232.
    • (2015) J Cardiovasc Pharmacol , vol.65 , pp. 226-232
    • Matavelli, L.C.1    Siragy, H.M.2
  • 50
    • 84939998893 scopus 로고    scopus 로고
    • A nonpeptide angiotensin II type 2 receptor agonist prevents renal inflammation in early diabetes
    • Matavelli LC, Zatz R, Siragy HM. A nonpeptide angiotensin II type 2 receptor agonist prevents renal inflammation in early diabetes. J Cardiovasc Pharm 2015; 65:371-376.
    • (2015) J Cardiovasc Pharm , vol.65 , pp. 371-376
    • Matavelli, L.C.1    Zatz, R.2    Siragy, H.M.3
  • 51
    • 84961970471 scopus 로고    scopus 로고
    • Angiotensin II type 2-receptor agonist C21 reduces proteinuria and oxidative stress in kidney of high-salt-fed obese Zucker rats
    • Patel S, Ali Q, Hussain T. Angiotensin II type 2-receptor agonist C21 reduces proteinuria and oxidative stress in kidney of high-salt-fed obese Zucker rats. Hypertension 2016; 67:906-915.
    • (2016) Hypertension , vol.67 , pp. 906-915
    • Patel, S.1    Ali, Q.2    Hussain, T.3


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