Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese zucker rats

Hypertension

Volumn 53, Issue 2, 2009, Pages 256-261

  Siddiqui, Athar H ^a   Ali, Quaisar ^a   Hussain, Tahir ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

Angiotensin ii receptors; Hypertension; Kidney; Obesity; Renin

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN RECEPTOR; GLUCOSE; KIDNEY RENIN; SODIUM; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE; RENIN; VASOCONSTRICTOR AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTERY CATHETERIZATION; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; BODY WEIGHT; CAROTID ARTERY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FLUID INTAKE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEART PROTECTION; HEART RATE; HYPERTENSION; KIDNEY CORTEX; LEAN BODY WEIGHT; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OBESITY; OSMOTIC PUMP; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR UPREGULATION; SODIUM EXCRETION; SODIUM RETENTION; SYSTOLIC BLOOD PRESSURE; URINARY EXCRETION; URINE VOLUME; WESTERN BLOTTING; ZUCKER RAT; ANIMAL; BLOOD PRESSURE; DISEASE MODEL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; KIDNEY PROXIMAL TUBULE; METABOLISM; PHYSIOLOGY;

ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTENSION; IMIDAZOLES; KIDNEY CORTEX; KIDNEY TUBULES, PROXIMAL; MALE; OBESITY; PYRIDINES; RATS; RATS, ZUCKER; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RENIN; VASOCONSTRICTOR AGENTS;

EID: 59849087336     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.108.126086     Document Type: Article

References (48)

1. de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger TH. International Union of Pharmacology XXIII: the angiotensin receptors. Pharmacol Rev. 2000;52:415-472.
2. Thomas D, Harris PJ, Morgan TO. Altered responsiveness of proximal tubule fluid reabsorption of peritubular angiotensin II in spontaneously hypertensive rats. J Hypertens. 1990;8:407-410.
3. Navar LG, Von Thun AM, Zou L, el-Dahr SS, Mitchell KD. Enhancement of intrarenal angiotensin II levels in 2 kidney 1 clip and angiotensin II induced hypertension. Blood Press. 1995;2(suppl):88-92.
4. Cheng HF, Wang JL, Vinson GP, Harris RC. Young SHR express increased type 1 angiotensin II receptors in renal proximal tubule. Am J Physiol. 1998;274:F10-F17.
5. Bonnardeaux A, Davies E, Jeunemaitre X, Féry I, Charm A, Clauser E, Tiret L, Cambien F, Corvol P, Soubrier F. Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. Hypertension. 1994;24:63-69.
6. Alonso-Galacia M, Brands MW, Zappe DH, Hal! JE. Hypertension in obese Zucker rats. Role of angiotensin II and adrenergic activity. Hypertension. 1996;28:1047-1054.
7. 1, receptor-mediated pressor and chronotropic effects. J Clin Invest. 1998; 101:527-535.
8. Carey RM. Angiotensin type-2 receptors and cardiovascular function: are angiotensin type-2 receptors protective? Curr Opin Cardiol. 2005;20: 264-269.
9. 2 receptor in a renal wrap hypertension model. Hypertension. 1999;33:1237-1242.
10. 2) angiotensin receptor. Proc Natl Acad Sci USA. 1999;96:6506-6510.
11. Ichiki T, Labosky PA, Shiota C, Okuyama S, Imagawa Y, Fogo A, Nimura F, Ichikawa I, Hogan BL, Inagami T. Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Nature. 1995;377:748-750.
12. Tamura M, Takagi T, Howard EF, Landon EJ, Steimle A, Tanner M, and Myers PR. Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation in synthetic diet-fed rats. J Hypertens. 2000; 18: 1239-1246.
13. 2) receptor protein in rat kidney. Hypertension. 1997;30:1238-1246.
14. 2 receptor subtypes in the rat kidney. Am J Physiol. 1999;277: F437-F446.
15. 2 receptor. Kidney Int. 2000;57:191-202.
16. Moore AF, Heiderstadt NT, Hunag E, Howell NL, Wang ZQ, Siragy HM, Carey RM. Selective inhibition of the renal angiotensin type 2 receptor increases blood pressure in conscious rats. Hypertension. 2001 ;37: 1285-1291.
17. Hakam AC, Hussain T. Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats. Hypertension. 2005;45:270-275.
18. Hakam AC, Hussain T. Angiotensin II type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not in lean Zucker rats. Hypertension. 2006;47:1117-1124.
19. Kurtz TW, Morris RC. Pershad Singh HA. The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension. 1989; 13: 896-901.
20. Fujiwara K, Hayashi K, Matsuda H, Kubota E, Honda M, Ozawa Y, Saruta T. Altered pressure-natriuresis in obese Zucker rats. Hypertension. 1999;33:1470-1475.
21. Granger JP, West D, Scott J. Abnormal pressure natriuresis in the dog model of obesity-induced hypertension. Hypertension. 1994;23:18-111.
22. Hall JE. The kidney, hypertension, and obesity. Hypertension. 2003;41: 625-633.
23. 1 receptor function in obese Zucker rat. Clin Exp Hypertens. 2003;25:35-47.
24. Shah S, Hussain T. Enhanced angiotensin II-induced activation of Na+,K+-ATPase in the proximal tubules of obese Zucker rats. Clin Exp Hypertens. 2006;28:29-40.
25. 1 receptor blockade or angiotensin-converting enzyme inhibition in obese Zucker rats. Clin Exp Pharmacol Physiol. 2001;28: 433-440.
26. Xu ZG, Lanting L, Vaziri ND, Li Z, Sepassi L, Rodriguez-Iturbe B, Natarajan R. Upregulation of angiotensin II type 1 receptor, inflammatory mediators, and enzymes of arachidonate metabolism in obese Zucker rat kidney: reversal by angiotensin II type 1 receptor blockade. Circulation. 2005;111:1962-1969.
27. Harker CT, O'Donnel MP, Kasiske BL, Keane WF, Katz SA. The renin-angiotensin system in the type II diabetic obese Zucker rat. J Am Soc Nephrol. 1993;4:1354-1361.
28. 2 antagonist, CGP 42112B. Exp Physiol. 1992;77:761-764.
29. Weisinger RS, Blair-West JR, Denton DA, Tarjan E. Role of brain angiotensin II in thirst and sodium appetite of sheep. Am J Physiol. 1997;273:R187-R196.
30. 2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats. Exp Physiol. 1993;78:767-774.
31. Abrão Saad W, Antonio De Arruda Camargo L, Sérgio Cerri P, Simões S, Abrão Saad W, Garcia G, Izabel Gutierrez L, Guarda I, Saad Guarda R. Influence of arginine vasopressin receptors and angiotensin receptor subtypes on the water intake and arterial blood pressure induced by vasopressin injected into the lateral septal area of the rat. Auton Neurosci. 2004;111:66-70.
32. 2 and cholinergic receptor antagonism on drinking in water-deprived rats. Regul Pept. 1996;66:41-46.
33. 2-receptor antagonists on drinking evoked by angiotensin II or water deprivation in rats. Brain Res. 1994;648:46-52.
34. Hein L, Barsh GS, Pratt RE, Dzau VJ, Kobilka BK. Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Nature. 1995;377:744-747.
35. Cefalu WT. Insulin resistance: cellular and clinical concepts. Exp Biol Med. 2001;226:13-26.
36. 1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats. Obesity (Silver Spring). 2008;16:770-776.
37. Zhao Y, Foryst-Ludwig A, Bruemmer D, Culman J, Bader M, Unger T, Kintscher U. Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation. J Neurochem. 2005;94:1395-1401.
38. Kim MK, Chae YN, Son MH, Kim SH, Kim JK, Moon HS, Park CS, Bae MH, Kim E, Han T, Choi HH, Shin YA, Ann BN, Lee CH, Lim JI, Shin CY. PAR-5359, a well balanced PPARα/γ dual agonist, exhibits equivalent antidiabetic and hypolipidemic activities in vitro and in vivo. Eur J Pharmacol. 2008;595:119-125.
39. 1 receptor-mediated vasocontractile response to ANG II in endothelium-denuded aorta of obese Zucker rats. Am J Physiol Heart Circ Physiol. 2007;292:H1722-H1727.
40. Siragy HM, Xue C, Abadir P, Carey RM. Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. Hypertension. 2005;45:133-137.
41. Bonnet F, Candido R, Carey RM, Casley D, Russo LM, Osicka TM, Cooper ME, Cao Z. Renal expression of angiotensin receptors in long-term diabetes and the effects of angiotensin type 1 receptor blockade. J Hypertens. 2002;20:1615-1624.
42. 2 receptors. Am J Physiol Renal Physiol. 2001;280:F254-F265.
43. 2 receptors promote natriuresis in streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol. 2006;290:F503-F508.
44. Mezzano S, Droguett A, Burgos ME, Ardiles LG, Flores CA, Carosi I, Vio CP, Ruiz-Ortega, Egido J. Renin-angiotensin system activation and interstitial inflammation in human diabetic nephropathy. Kidney Int. 2003;64:S64-S70.
45. 2 Receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats. Am J Physiol Regul Integr Comp Physiol. 2008;295:R144-R154.
46. Marwaha A, Lokhandwala MF. Diminished natriuretic response to dopamine Dl receptor agonist, SKF-38393 in obese Zucker rats. Clin Exp Hypertens. 2003;25:509-515.
47. Hussain T, Beheray SA, Lokhandwala MF. Defective dopamine receptor function in proximal tubules of obese Zucker rats. Hypertension. 1999; 34:1091-1096.
48. Zeigler DW, Patel KP. Reduced renal responses to an acute saline load in obese Zucker rats. Am J Physiol. 1991;261:R712-R718.