Anticancer copper pyridine benzimidazole complexes: ROS generation, biomolecule interactions, and cytotoxicity

Journal of Inorganic Biochemistry

Volumn 167, Issue , 2017, Pages 89-99

  Prosser, Kathleen E ^a   Chang, Stephanie W ^a   Saraci, Felix ^a   Le, Phuc H ^a   Walsby, Charles J ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Albumin; Anticancer; Copper; DNA; Reactive oxygen species

Indexed keywords

ANTINEOPLASTIC AGENT; ASCORBIC ACID; BENZIMIDAZOLE DERIVATIVE; BUFFER; CISPLATIN; COPPER COMPLEX; HUMAN SERUM ALBUMIN; PYRIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; BENZIMIDAZOLE; COORDINATION COMPOUND; COPPER; CYTOTOXIN; DNA;

A549 CELL LINE; AGAR GEL ELECTROPHORESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ELECTRON SPIN RESONANCE; EPITHELIUM BASAL CELL; IC50; IN VITRO STUDY; INTERACTIONS WITH DNA; MOLECULAR INTERACTION; ULTRAVIOLET SPECTROSCOPY; A-549 CELL LINE; CHEMISTRY; DRUG SCREENING; HUMAN; METABOLISM; NEOPLASMS; PATHOLOGY; SYNTHESIS;

A549 CELLS; ANTINEOPLASTIC AGENTS; BENZIMIDAZOLES; COORDINATION COMPLEXES; COPPER; CYTOTOXINS; DNA, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; NEOPLASMS; PYRIDINES; REACTIVE OXYGEN SPECIES;

EID: 85000814899     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2016.11.006     Document Type: Article

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