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Journal of Biological Inorganic Chemistry

Volumn 15, Issue 2, 2010, Pages 131-145

Serum-protein interactions with anticancer Ru(III) complexes KP1019 and KP418 characterized by EPR

(4) Cetinbas, Naniye a Webb, Michael I a Dubland, Joshua A a Walsby, Charles J a

a SIMON FRASER UNIVERSITY (Canada)

Author keywords

Electron paramagnetic resonance; Human serum albumin; Human serum transferrin; KP1019; KP418

Indexed keywords

ANTINEOPLASTIC AGENT; APOPROTEIN; IMIDAZOLE DERIVATIVE; INDAZOLIUM; SERUM ALBUMIN; TRANSFERRIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; COVALENT BOND; ELECTRON SPIN RESONANCE; HUMAN; HYDROPHOBICITY; OXIDATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL;

ANTINEOPLASTIC AGENTS; APOPROTEINS; BINDING SITES; ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; INDAZOLES; LIGANDS; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; RUTHENIUM COMPOUNDS; SERUM ALBUMIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77949275871 PISSN: 09498257 EISSN: None Source Type: Journal
DOI: 10.1007/s00775-009-0578-5 Document Type: Article

Times cited : (78)

References (73)

1
- 0141811013
- Recent developments in the field of tumor-inhibiting metal complexes
- DOI 10.2174/1381612033454180
- M Galanski VB Arion MA Jakupec BK Keppler 2003 Curr Pharm Des 9 2078 2089 10.2174/1381612033454180 1:CAS:528:DC%2BD3sXnsV2gu7c%3D 14529417 (Pubitemid 37142439)
- (2003) Current Pharmaceutical Design , vol.9 , Issue.25 , pp. 2078-2089
- Galanski, M.¹ Arion, V.B.² Jakupec, M.A.³ Keppler, B.K.⁴

2
- 33845966872
- Dyson PJ, Sava G (2006) Dalton Trans 1929-1933
- (2006) Dalton Trans , pp. 1929-1933
- Dyson, P.J.¹ Sava, G.²

3
- 33745384809
- From bench to bedside - preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A)
- DOI 10.1016/j.jinorgbio.2006.02.013, PII S0162013406000754
- CG Hartinger S Zorbas-Seifried MA Jakupec B Kynast H Zorbas BK Keppler 2006 J Inorg Biochem 100 891 904 10.1016/j.jinorgbio.2006.02.013 1:CAS:528:DC%2BD28XksVCluro%3D 16603249 (Pubitemid 44308176)
- (2006) Journal of Inorganic Biochemistry , vol.100 , Issue.5-6 , pp. 891-904
- Hartinger, C.G.¹ Zorbas-Seifried, S.² Jakupec, M.A.³ Kynast, B.⁴ Zorbas, H.⁵ Keppler, B.K.⁶

4
- 59449101302
- 10.1097/CAD.0b013e328322fbc5 1:CAS:528:DC%2BD1MXhvVSitLk%3D 19209025
- F Lentz A Drescher A Lindauer M Henke RA Hilger CG Hartinger ME Scheulen C Dittrich BK Keppler U Jaehde 2009 Anticancer Drugs 20 97 103 10.1097/CAD.0b013e328322fbc5 1:CAS:528:DC%2BD1MXhvVSitLk%3D 19209025
- (2009) Anticancer Drugs , vol.20 , pp. 97-103
- Lentz, F.¹ Drescher, A.² Lindauer, A.³ Henke, M.⁴ Hilger, R.A.⁵ Hartinger, C.G.⁶ Scheulen, M.E.⁷ Dittrich, C.⁸ Keppler, B.K.⁹ Jaehde, U.¹⁰

5
- 37149008995
- 10.2533/chimia.2007.692 1:CAS:528:DC%2BD2sXhsVyhsbzK
- I Bratsos S Jedner T Gianferrara E Alessio 2007 Chimia 61 692 697 10.2533/chimia.2007.692 1:CAS:528:DC%2BD2sXhsVyhsbzK
- (2007) Chimia , vol.61 , pp. 692-697
- Bratsos, I.¹ Jedner, S.² Gianferrara, T.³ Alessio, E.⁴

6
- 10844269461
- Ruthenium antimetastatic agents
- DOI 10.2174/1568026043387421
- E Alessio G Mestroni A Bergamo G Sava 2004 Curr Top Med Chem 4 1525 1535 10.2174/1568026043387421 1:CAS:528:DC%2BD2cXhtVKmsbrP 15579094 (Pubitemid 39662663)
- (2004) Current Topics in Medicinal Chemistry , vol.4 , Issue.15 , pp. 1525-1535
- Alessio, E.¹ Mestroni, G.² Bergamo, A.³ Sava, G.⁴

7
- 0026685102
- 1:CAS:528:DyaK38Xks1anurs%3D 1418038
- A Galeano MR Berger BK Keppler 1992 Arzneimittelforschung 42 821 824 1:CAS:528:DyaK38Xks1anurs%3D 1418038
- (1992) Arzneimittelforschung , vol.42 , pp. 821-824
- Galeano, A.¹ Berger, M.R.² Keppler, B.K.³

8
- 0031415671
- Preclinical activity of trans-indazolium [tetrachlorobisindazoleruthenate (III)] (NSC 666158; IndCR; KP 1019) against tumour colony-forming units and haematopoietic progenitor cells
- DOI 10.1016/S0959-8049(97)00277-3, PII S0959804997002773
- H Depenbrock S Schmelcher R Peter BK Keppler G Weirich T Block J Rastetter AR Hanauske 1997 Eur J Cancer 33 2404 2410 10.1016/S0959-8049(97) 00277-3 1:CAS:528:DyaK1cXntVGlsA%3D%3D 9616290 (Pubitemid 28129185)
- (1997) European Journal of Cancer , vol.33 , Issue.14 , pp. 2404-2410
- Depenbrock, H.¹ Schmelcher, S.² Peter, R.³ Keppler, B.K.⁴ Weirich, G.⁵ Block, T.⁶ Rastetter, J.⁷ Hanauske, A.-R.⁸

9
- 0037141471
- In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer
- DOI 10.1038/sj.bjc.6600290
- RE Aird J Cummings AA Ritchie M Muir RE Morris H Chen PJ Sadler DI Jodrell 2002 Br J Cancer 86 1652 1657 10.1038/sj.bjc.6600290 1:CAS:528:DC%2BD38XkvVaitbg%3D 12085218 (Pubitemid 34628122)
- (2002) British Journal of Cancer , vol.86 , Issue.10 , pp. 1652-1657
- Aird, R.E.¹ Cummings, J.² Ritchie, A.A.³ Muir, M.⁴ Morris, R.E.⁵ Chen, H.⁶ Sadler, P.J.⁷ Jodrell, D.I.⁸

10
- 13244250963
- Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells
- DOI 10.1007/s00432-004-0617-0
- S Kapitza M Pongratz MA Jakupec P Heffeter W Berger L Lackinger BK Keppler B Marian 2005 J Cancer Res Clin Oncol 131 101 110 10.1007/s00432-004- 0617-0 1:CAS:528:DC%2BD2MXntF2lsA%3D%3D 15503135 (Pubitemid 40192935)
- (2005) Journal of Cancer Research and Clinical Oncology , vol.131 , Issue.2 , pp. 101-110
- Kapitza, S.¹ Pongratz, M.² Jakupec, M.A.³ Heffeter, P.⁴ Berger, W.⁵ Lackinger, L.⁶ Keppler, B.K.⁷ Marian, B.⁸

11
- 22844452813
- The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells
- DOI 10.1016/j.canlet.2005.01.002, PII S0304383505000340
- S Kapitza A Jakupec Michael M Uhl K Keppler Bernhard B Marian 2005 Cancer Lett 226 115 121 10.1016/j.canlet.2005.01.002 1:CAS:528:DC%2BD2MXmsVaisbk%3D 16039951 (Pubitemid 41039079)
- (2005) Cancer Letters , vol.226 , Issue.2 , pp. 115-121
- Kapitza, S.¹ Jakupec, M.A.² Uhl, M.³ Keppler, B.K.⁴ Marian, B.⁵

12
- 0026563731
- 1:CAS:528:DyaK38Xktl2qsLw%3D 1373006
- ED Kreuser BK Keppler WE Berdel A Piest E Thiel 1992 Semin Oncol 19 73 81 1:CAS:528:DyaK38Xktl2qsLw%3D 1373006
- (1992) Semin Oncol , vol.19 , pp. 73-81
- Kreuser, E.D.¹ Keppler, B.K.² Berdel, W.E.³ Piest, A.⁴ Thiel, E.⁵

13
- 0029868406
- Comparison of the antiproliferative activity of two antitumour ruthenium(III) complexes with their apotransferrin and transferrin-bound forms in a human colon cancer cell line
- DOI 10.1155/MBD.1996.15
- F Kratz BK Keppler M Hartmann L Messon MR Berger 1996 Met Based Drugs 3 15 23 10.1155/MBD.1996.15 1:CAS:528:DyaK28XktV2jtrY%3D 18472789 (Pubitemid 26075454)
- (1996) Metal-Based Drugs , vol.3 , Issue.1 , pp. 15-23
- Kratz, F.¹ Keppler, B.K.² Hartmann, M.³ Messori, L.⁴ Berger, M.R.⁵

14
- 0031971967
- Comparative nephrotoxicity of some antitumour-active platinum and ruthenium complexes in rats
- DOI 10.1002/(SICI)1099-1263(199803/04)18:2<93::AID-JAT472>3.0.CO;2- W
- L Kersten H Braunlich BK Keppler C Gliesing M Wendelin J Westphal 1998 J Appl Toxicol 18 93 101 10.1002/(SICI)1099-1263(199803/04)18:2<93::AID- JAT472>3.0.CO;2-W 1:CAS:528:DyaK1cXislWhtb4%3D 9570691 (Pubitemid 28168268)
- (1998) Journal of Applied Toxicology , vol.18 , Issue.2 , pp. 93-101
- Kersten, L.¹ Braunlich, H.² Keppler, B.K.³ Gliesing, C.⁴ Wendelin, M.⁵ Westphal, J.⁶

15
- 0345830489
- The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: An NMR evaluation
- DOI 10.1016/j.jinorgbio.2003.12.003
- M Bacac ACG Hotze K van der Schilden JG Haasnoot S Pacor E Alessio G Sava J Reedijk 2004 J Inorg Biochem 98 402 412 10.1016/j.jinorgbio.2003.12.003 1:CAS:528:DC%2BD2cXjsVyksQ%3D%3D 14729322 (Pubitemid 38083159)
- (2004) Journal of Inorganic Biochemistry , vol.98 , Issue.2 , pp. 402-412
- Bacac, M.¹ Hotze, A.C.G.² Van Der Schilden, K.³ Haasnoot, J.G.⁴ Pacor, S.⁵ Alessio, E.⁶ Sava, G.⁷ Reedijk, J.⁸

16
- 48649108557
- 10.1021/ic800506g 1:CAS:528:DC%2BD1cXnt1Wit7Y%3D 18553904
- B Cebrian-Losantos E Reisner CR Kowol A Roller S Shova VB Arion BK Keppler 2008 Inorg Chem 47 6513 6523 10.1021/ic800506g 1:CAS:528: DC%2BD1cXnt1Wit7Y%3D 18553904
- (2008) Inorg Chem , vol.47 , pp. 6513-6523
- Cebrian-Losantos, B.¹ Reisner, E.² Kowol, C.R.³ Roller, A.⁴ Shova, S.⁵ Arion, V.B.⁶ Keppler, B.K.⁷

17
- 34247616687
- 4L(S-dmso)ruthenate(III)] (L = imidazole, indazole, 1,2,4-triazole, 4-amino-1,2,4-triazole, and 1-methyl-1,2,4-triazole): Aquation, redox properties, protein binding, and antiproliferative activity
- DOI 10.1021/jm061081y
- M Groessl E Reisner CG Hartinger R Eichinger O Semenova AR Timerbaev MA Jakupec VB Arion BK Keppler 2007 J Med Chem 50 2185 2193 10.1021/jm061081y 1:CAS:528:DC%2BD2sXjvFCisLk%3D 17402720 (Pubitemid 46683071)
- (2007) Journal of Medicinal Chemistry , vol.50 , Issue.9 , pp. 2185-2193
- Groessl, M.¹ Reisner, E.² Hartinger, C.G.³ Eichinger, R.⁴ Semenova, O.⁵ Timerbaev, A.R.⁶ Jakupec, M.A.⁷ Arion, V.B.⁸ Keppler, B.K.⁹

18
- 0034847504
- 2] investigated by means of HPCE and HPLC-MS
- DOI 10.1007/s007750000203
- A Kung T Pieper R Wissiack E Rosenberg BK Keppler 2001 J Biol Inorg Chem 6 292 299 10.1007/s007750000203 1:CAS:528:DC%2BD3MXjtVehtbg%3D 11315565 (Pubitemid 32823962)
- (2001) Journal of Biological Inorganic Chemistry , vol.6 , Issue.3 , pp. 292-299
- Kung, A.¹ Pieper, T.² Wissiack, R.³ Rosenberg, E.⁴ Keppler, B.K.⁵

19
- 0034529905
- 10.1155/MBD.2000.225 1:CAS:528:DC%2BD3MXitVKisg%3D%3D 18475949
- T Pieper W Peti BK Keppler 2000 Met Based Drugs 7 225 232 10.1155/MBD.2000.225 1:CAS:528:DC%2BD3MXitVKisg%3D%3D 18475949
- (2000) Met Based Drugs , vol.7 , pp. 225-232
- Pieper, T.¹ Peti, W.² Keppler, B.K.³

20
- 0036161069
- Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A
- DOI 10.1016/S0959-8049(01)00389-6, PII S0959804901003896
- G Sava A Bergamo S Zorzet B Gava C Casarsa M Cocchietto A Furlani V Scarcia B Serli E Iengo E Alessio G Mestroni 2002 Eur J Cancer 38 427 435 10.1016/S0959-8049(01)00389-6 1:CAS:528:DC%2BD38XovFSgsw%3D%3D 11818210 (Pubitemid 34123316)
- (2002) European Journal of Cancer , vol.38 , Issue.3 , pp. 427-435
- Sava, G.¹ Bergamo, A.² Zorzet, S.³ Gava, B.⁴ Casarsa, C.⁵ Cocchietto, M.⁶ Furlani, A.⁷ Scarcia, V.⁸ Serli, B.⁹ Iengo, E.¹⁰ Alessio, E.¹¹ Mestroni, G.¹²

21
- 17544381239
- Redox-active antineoplastic ruthenium complexes with indazole: Correlation of in vitro potency and reduction potential
- DOI 10.1021/jm0490742
- MA Jakupec E Reisner A Eichinger M Pongratz VB Arion M Galanski CG Hartinger BK Keppler 2005 J Med Chem 48 2831 2837 10.1021/jm0490742 1:CAS:528:DC%2BD2MXit1KrtrY%3D 15828821 (Pubitemid 40552909)
- (2005) Journal of Medicinal Chemistry , vol.48 , Issue.8 , pp. 2831-2837
- Jakupec, M.A.¹ Reisner, E.² Eichinger, A.³ Pongratz, M.⁴ Arion, V.B.⁵ Galanski, M.⁶ Hartinger, C.G.⁷ Keppler, B.K.⁸

22
- 22544449266
- Structure-function relationships within Keppler-type antitumor ruthenium(III) complexes: The case of 2-aminothiazolium[frans-tetrachlorobis(2- aminothiazole)ruthenate(III)]
- DOI 10.1021/ic050194p
- P Mura F Piccioli C Gabbiani M Camalli L Messori 2005 Inorg Chem 44 4897 4899 10.1021/ic050194p 1:CAS:528:DC%2BD2MXltVynurg%3D 15998012 (Pubitemid 41022490)
- (2005) Inorganic Chemistry , vol.44 , Issue.14 , pp. 4897-4899
- Mura, P.¹ Piccioli, F.² Gabbiani, C.³ Camalli, M.⁴ Messori, L.⁵

23
- 0021782306
- 10.1016/S0065-3233(08)60065-0 1:CAS:528:DyaL2MXmtV2js70%3D 3904348
- T Peters 1985 Adv Protein Chem 37 161 245 10.1016/S0065-3233(08)60065-0 1:CAS:528:DyaL2MXmtV2js70%3D 3904348
- (1985) Adv Protein Chem , vol.37 , pp. 161-245
- Peters, T.¹

24
- 4344691171
- Ravera M, Baracco S, Cassino C, Zanello P, Osella D (2004) Dalton Trans 2347-2351
- (2004) Dalton Trans , pp. 2347-2351
- Ravera, M.¹ Baracco, S.² Cassino, C.³ Zanello, P.⁴ Osella, D.⁵

25
- 7444254089
- 10.1021/ic049479c 1:CAS:528:DC%2BD2cXns12rt7s%3D 15500346
- E Reisner VB Arion MFC Guedes da Silva R Lichtenecker A Eichinger BK Keppler VY Kukushkin AJL Pombeiro 2004 Inorg Chem 43 7083 7093 10.1021/ic049479c 1:CAS:528:DC%2BD2cXns12rt7s%3D 15500346
- (2004) Inorg Chem , vol.43 , pp. 7083-7093
- Reisner, E.¹ Arion, V.B.² Guedes Da Silva, M.F.C.³ Lichtenecker, R.⁴ Eichinger, A.⁵ Keppler, B.K.⁶ Kukushkin, V.Y.⁷ Pombeiro, A.J.L.⁸

26
- 1642575354
- Biological role of adduct formation of the ruthenium(III) complex NAMI-A with serum albumin and serum transferrin
- DOI 10.1023/A:1026243000320
- A Bergamo L Messori F Piccioli M Cocchietto G Sava 2003 Invest New Drugs 21 401 411 10.1023/A:1026243000320 1:CAS:528:DC%2BD3sXotleitrs%3D 14586207 (Pubitemid 38124979)
- (2003) Investigational New Drugs , vol.21 , Issue.4 , pp. 401-411
- Bergamo, A.¹ Messori, L.² Piccioli, F.³ Cocchietto, M.⁴ Sava, G.⁵

27
- 48149111843
- 10.1007/s00775-008-0378-3 1:CAS:528:DC%2BD1cXovFOmsbs%3D 18438690
- M Brindell I Stawoska J Supel A Skoczowski G Stochel R Eldik 2008 J Biol Inorg Chem 13 909 918 10.1007/s00775-008-0378-3 1:CAS:528:DC%2BD1cXovFOmsbs%3D 18438690
- (2008) J Biol Inorg Chem , vol.13 , pp. 909-918
- Brindell, M.¹ Stawoska, I.² Supel, J.³ Skoczowski, A.⁴ Stochel, G.⁵ Eldik, R.⁶

28
- 0027993919
- 1:CAS:528:DyaK2cXht1Cgu7k%3D 8300587
- F Kratz M Hartmann B Keppler L Messori 1994 J Biol Chem 269 2581 2588 1:CAS:528:DyaK2cXht1Cgu7k%3D 8300587
- (1994) J Biol Chem , vol.269 , pp. 2581-2588
- Kratz, F.¹ Hartmann, M.² Keppler, B.³ Messori, L.⁴

29
- 2442449173
- 2] and serum proteins
- DOI 10.1016/j.jinorgbio.2004.04.002, PII S0162013404001060
- F Piccioli S Sabatini L Messori P Orioli CG Hartinger BK Keppler 2004 J Inorg Biochem 98 1135 1142 10.1016/j.jinorgbio.2004.04.002 1:CAS:528: DC%2BD2cXktVCmt7k%3D 15149825 (Pubitemid 38638512)
- (2004) Journal of Inorganic Biochemistry , vol.98 , Issue.6 , pp. 1135-1142
- Piccioli, F.¹ Sabatini, S.² Messori, L.³ Orioli, P.⁴ Hartinger, Ch.G.⁵ Keppler, B.K.⁶

30
- 24644497689
- Two dimensional separation schemes for investigation of the interaction of an anticancer ruthenium(III) compound with plasma proteins
- DOI 10.1039/b508060f
- M Sulyok S Hann CG Hartinger BK Keppler G Stingeder G Koellensperger 2005 J Anal At Spectrom 20 856 863 10.1039/b508060f 1:CAS:528:DC%2BD2MXpt1aiu7k%3D (Pubitemid 41284843)
- (2005) Journal of Analytical Atomic Spectrometry , vol.20 , Issue.9 , pp. 856-863
- Sulyok, M.¹ Hann, S.² Hartinger, C.G.³ Keppler, B.K.⁴ Stingeder, G.⁵ Koellensperger, G.⁶

31
- 19544367738
- Comparative binding of antitumor indazolium [trans-tetrachlorobis(1H- indazole)ruthenate(III)] to serum transport proteins assayed by capillary zone electrophoresis
- DOI 10.1016/j.ab.2005.03.020, PII S0003269705002058
- AR Timerbaev AV Rudnev O Semenova CG Hartinger BK Keppler 2005 Anal Biochem 341 326 333 10.1016/j.ab.2005.03.020 1:CAS:528:DC%2BD2MXktleju7c%3D 15907879 (Pubitemid 40731491)
- (2005) Analytical Biochemistry , vol.341 , Issue.2 , pp. 326-333
- Timerbaev, A.R.¹ Rudnev, A.V.² Semenova, O.³ Hartinger, C.G.⁴ Keppler, B.K.⁵

32
- 0034737805
- Studies on the interactions between human serum albumin and trans-indazolium (bisindazole) tetrachlororuthenate(III)
- DOI 10.1016/S0162-0134(00)00062-3, PII S0162013400000623
- L Trynda-Lemiesz A Karaczyn BK Keppler H Kozlowski 2000 J Inorg Biochem 78 341 346 10.1016/S0162-0134(00)00062-3 1:CAS:528:DC%2BD3cXksVGltL0%3D 10857915 (Pubitemid 30412021)
- (2000) Journal of Inorganic Biochemistry , vol.78 , Issue.4 , pp. 341-346
- Trynda-Lemiesz, L.¹ Karaczyn, A.² Keppler, B.K.³ Kozlowski, H.⁴

33
- 0033103292
- Studies on the interactions between human serum albumin and imidazolium [trans-tetrachlorobis (imidazol) ruthenate(III)]
- DOI 10.1016/S0162-0134(99)00004-5, PII S0162013499000045
- L Trynda-Lemiesz BK Keppler H Kozlowski 1999 J Inorg Biochem 73 123 128 10.1016/S0162-0134(99)00004-5 1:CAS:528:DyaK1MXjtFChtrw%3D 10331241 (Pubitemid 29226604)
- (1999) Journal of Inorganic Biochemistry , vol.73 , Issue.3 , pp. 123-128
- Trynda-Lemiesz, L.¹ Keppler, B.K.² Kozlowski, H.³

34
- 11244291325
- - with a DNA-relevant nucleobase and thioethers: Insight into biological action
- DOI 10.1021/ic048967h
- A Egger VB Arion E Reisner B Cebrian-Losantos S Shova G Trettenhahn BK Keppler 2005 Inorg Chem 44 122 132 10.1021/ic048967h 1:CAS:528: DC%2BD2cXhtVCrsbvF 15627368 (Pubitemid 40068848)
- (2005) Inorganic Chemistry , vol.44 , Issue.1 , pp. 122-132
- Egger, A.¹ Arion, V.B.² Reisner, E.³ Cebrian-Losantos, B.⁴ Shova, S.⁵ Trettenhahn, G.⁶ Keppler, B.K.⁷

35
- 41949111980
- 10.1016/j.jinorgbio.2007.11.018 1:CAS:528:DC%2BD1cXkvVyjsL4%3D 18222004
- M Groessl CG Hartinger PJ Dyson BK Keppler 2008 J Inorg Biochem 102 1060 1065 10.1016/j.jinorgbio.2007.11.018 1:CAS:528:DC%2BD1cXkvVyjsL4%3D 18222004
- (2008) J Inorg Biochem , vol.102 , pp. 1060-1065
- Groessl, M.¹ Hartinger, C.G.² Dyson, P.J.³ Keppler, B.K.⁴

36
- 0035812217
- Investigations into the interaction between tumor-inhibiting ruthenium(III) complexes and nucleotides by capillary electrophoresis
- DOI 10.1016/S0378-4347(01)00205-5, PII S0378434701002055
- A Kung T Pieper BK Keppler 2001 J Chromatogr B Biomed Sci Appl 759 81 89 10.1016/S0378-4347(01)00205-5 1:CAS:528:DC%2BD3MXks1Oiurg%3D 11499632 (Pubitemid 32595439)
- (2001) Journal of Chromatography B: Biomedical Sciences and Applications , vol.759 , Issue.1 , pp. 81-89
- Kung, A.¹ Pieper, T.² Keppler, B.K.³

37
- 0034840455
- Biophysical analysis of natural, double-helical DNA modified by anticancer heterocyclic complexes of ruthenium(III) in cell-free media
- DOI 10.1007/s007750100223
- J Malina O Novakova BK Keppler E Alessio V Brabec 2001 J Biol Inorg Chem 6 435 445 10.1007/s007750100223 1:CAS:528:DC%2BD3MXjvFKitb8%3D 11372202 (Pubitemid 32822134)
- (2001) Journal of Biological Inorganic Chemistry , vol.6 , Issue.4 , pp. 435-445
- Malina, J.¹ Novakova, O.² Keppler, B.K.³ Alessio, E.⁴ Brabec, V.⁵

38
- 3042845837
- Cytotoxicity of the organic ruthenium anticancer drug Nami-A is correlated with DNA binding in four different human tumor cell lines
- DOI 10.1007/s00280-004-0773-6
- D Pluim RCAM van Waardenburg JH Beijnen JHM Schellens 2004 Cancer Chemother Pharmacol 54 71 78 10.1007/s00280-004-0773-6 1:CAS:528: DC%2BD2cXksFSitLc%3D 15034754 (Pubitemid 38858368)
- (2004) Cancer Chemotherapy and Pharmacology , vol.54 , Issue.1 , pp. 71-78
- Pluim, D.¹ Van Waardenburg, R.C.A.M.² Beijnen, J.H.³ Schellens, J.H.M.⁴

39
- 33645277617
- Schluga P, Hartinger CG, Egger A, Reisner E, Galanski M, Jakupec MA, Keppler BK (2006) Dalton Trans 1796-1802
- (2006) Dalton Trans , pp. 1796-1802
- Schluga, P.¹ Hartinger, C.G.² Egger, A.³ Reisner, E.⁴ Galanski, M.⁵ Jakupec, M.A.⁶ Keppler, B.K.⁷

40
- 38149017955
- 10.1016/j.jinorgbio.2007.09.008 1:CAS:528:DC%2BD1cXoslCjsA%3D%3D 18022241
- C Tan J Liu H Li W Zheng S Shi L Chen L Ji 2008 J Inorg Biochem 102 347 358 10.1016/j.jinorgbio.2007.09.008 1:CAS:528:DC%2BD1cXoslCjsA%3D%3D 18022241
- (2008) J Inorg Biochem , vol.102 , pp. 347-358
- Tan, C.¹ Liu, J.² Li, H.³ Zheng, W.⁴ Shi, S.⁵ Chen, L.⁶ Ji, L.⁷

41
- 33646956829
- 10.1021/cr9804238 1:CAS:528:DyaK1MXkslChtLc%3D 11749489
- MJ Clarke F Zhu DR Frasca 1999 Chem Rev 99 2511 2533 10.1021/cr9804238 1:CAS:528:DyaK1MXkslChtLc%3D 11749489
- (1999) Chem Rev , vol.99 , pp. 2511-2533
- Clarke, M.J.¹ Zhu, F.² Frasca, D.R.³

42
- 0018671415
- 1:CAS:528:DyaE1MXktFGnt7c%3D 444649
- A Leibman P Aisen 1979 Blood 53 1058 1065 1:CAS:528:DyaE1MXktFGnt7c%3D 444649
- (1979) Blood , vol.53 , pp. 1058-1065
- Leibman, A.¹ Aisen, P.²

43
- 0031567095
- 1:CAS:528:DyaK2sXhsFKmt7g%3D
- DR Richardson P Ponka 1997 Biochim Biophys Acta Rev Biomembr 1331 1 40 1:CAS:528:DyaK2sXhsFKmt7g%3D
- (1997) Biochim Biophys Acta Rev Biomembr , vol.1331 , pp. 1-40
- Richardson, D.R.¹ Ponka, P.²

44
- 0036783690
- 10.1016/S0010-8545(02)00025-5 1:CAS:528:DC%2BD38XntF2ktbg%3D
- MJ Clarke 2002 Coord Chem Rev 232 69 93 10.1016/S0010-8545(02)00025-5 1:CAS:528:DC%2BD38XntF2ktbg%3D
- (2002) Coord Chem Rev , vol.232 , pp. 69-93
- Clarke, M.J.¹

45
- 33645998774
- 10.2174/092986706776360941 1:CAS:528:DC%2BD28XkslKqtbs%3D 16611086
- I Kostova 2006 Curr Med Chem 13 1085 1107 10.2174/092986706776360941 1:CAS:528:DC%2BD28XkslKqtbs%3D 16611086
- (2006) Curr Med Chem , vol.13 , pp. 1085-1107
- Kostova, I.¹

46
- 0000459043
- 10.1155/MBD.1994.169 1:CAS:528:DyaK2MXhtF2it78%3D 18476228
- F Kratz BK Keppler L Messori C Smith EN Baker 1994 Met Based Drugs 1 169 173 10.1155/MBD.1994.169 1:CAS:528:DyaK2MXhtF2it78%3D 18476228
- (1994) Met Based Drugs , vol.1 , pp. 169-173
- Kratz, F.¹ Keppler, B.K.² Messori, L.³ Smith, C.⁴ Baker, E.N.⁵

47
- 0001752711
- 10.1007/s007750050074 1:CAS:528:DyaK2sXisFGks7s%3D
- CA Smith AJ SutherlandSmith BK Keppler F Kratz EN Baker 1996 J Biol Inorg Chem 1 424 431 10.1007/s007750050074 1:CAS:528:DyaK2sXisFGks7s%3D
- (1996) J Biol Inorg Chem , vol.1 , pp. 424-431
- Smith, C.A.¹ Sutherlandsmith, A.J.² Keppler, B.K.³ Kratz, F.⁴ Baker, E.N.⁵

48
- 20044391816
- Albumin: Biochemical properties and therapeutic potential
- DOI 10.1002/hep.20720
- GJ Quinlan GS Martin TW Evans 2005 Hepatology 41 1211 1219 10.1002/hep.20720 1:CAS:528:DC%2BD2MXlvVSntb0%3D 15915465 (Pubitemid 40770271)
- (2005) Hepatology , vol.41 , Issue.6 , pp. 1211-1219
- Quinlan, G.J.¹ Martin, G.S.² Evans, T.W.³

49
- 0027270167
- Steroid binding to human serum albumin and fragments thereof. Role of protein conformation and fatty acid content
- DOI 10.1016/0006-2952(93)90221-H
- MJE Fischer OJM Bos RF van der Linden J Wilting LHM Janssen 1993 Biochem Pharmacol 45 2411 2416 10.1016/0006-2952(93)90221-H 1:CAS:528:DyaK3sXlsFagsrw%3D 8328979 (Pubitemid 23189533)
- (1993) Biochemical Pharmacology , vol.45 , Issue.12 , pp. 2411-2416
- Fischer, M.J.E.¹ Bos, O.J.M.² Van Der Linden, R.F.³ Wilting, J.⁴ Janssen, L.H.M.⁵

50
- 0023223171
- Effect of protein concentration on the binding of gold(I) to human serum albumin
- DOI 10.1016/0006-2952(87)90548-X
- SM Pedersen 1987 Biochem Pharmacol 36 2661 2666 10.1016/0006-2952(87) 90548-X 1:STN:280:DyaL2s3ntVyksQ%3D%3D 3111487 (Pubitemid 17102925)
- (1987) Biochemical Pharmacology , vol.36 , Issue.16 , pp. 2661-2666
- Pedersen, S.M.¹

51
- 0016801988
- 1:CAS:528:DyaE28XmvFahsQ%3D%3D 1207674
- G Sudlow DJ Birkett DN Wade 1975 Mol Pharmacol 11 824 832 1:CAS:528:DyaE28XmvFahsQ%3D%3D 1207674
- (1975) Mol Pharmacol , vol.11 , pp. 824-832
- Sudlow, G.¹ Birkett, D.J.² Wade, D.N.³

52
- 0017174391
- 1:CAS:528:DyaE2sXjslCqsA%3D%3D 1004490
- G Sudlow DJ Birkett DN Wade 1976 Mol Pharmacol 12 1052 1061 1:CAS:528:DyaE2sXjslCqsA%3D%3D 1004490
- (1976) Mol Pharmacol , vol.12 , pp. 1052-1061
- Sudlow, G.¹ Birkett, D.J.² Wade, D.N.³

53
- 3042673067
- 10.1186/1472-6807-3-6 12846933
- PA Zunszain J Ghuman T Komatsu E Tsuchida S Curry 2003 BMC Struct Biol 3 6 10.1186/1472-6807-3-6 12846933
- (2003) BMC Struct Biol , vol.3 , pp. 6
- Zunszain, P.A.¹ Ghuman, J.² Komatsu, T.³ Tsuchida, E.⁴ Curry, S.⁵

54
- 0002069966
- Anastassopoulou J, Collery Ph, Etienne JC, Theophanides Th (eds) John Libbey Eurotext, Paris
- Kratz F, Mulinacci N, Messori L, Bertini I, Keppler BK (1992) In: Anastassopoulou J, Collery Ph, Etienne JC, Theophanides Th (eds) Metal ions in biology and medicine, vol 2. John Libbey Eurotext, Paris, pp 69-74
- (1992) Metal Ions in Biology and Medicine , vol.2 , pp. 69-74
- Kratz, F.¹ Mulinacci, N.² Messori, L.³ Bertini, I.⁴ Keppler, B.K.⁵

55
- 0003921971
- Wiley New York
- Kratz F (1993) Metal complexes in cancer chemotherapy. Wiley, New York, pp 391-429
- (1993) Metal Complexes in Cancer Chemotherapy , pp. 391-429
- Kratz, F.¹

56
- 0001663293
- 10.1021/ic960355c 1:CAS:528:DyaK28XksV2lsro%3D 11666690
- MJ Clarke V Bailey P Doan C Hiller KJ LaChance-Galang H Daghlian S Mandal CM Bastos D Lang 1996 Inorg Chem 35 4896 4903 10.1021/ic960355c 1:CAS:528:DyaK28XksV2lsro%3D 11666690
- (1996) Inorg Chem , vol.35 , pp. 4896-4903
- Clarke, M.J.¹ Bailey, V.² Doan, P.³ Hiller, C.⁴ Lachance-Galang, K.J.⁵ Daghlian, H.⁶ Mandal, S.⁷ Bastos, C.M.⁸ Lang, D.⁹

57
- 0003593324
- Oxford University Press Oxford
- Abragam A, Bleaney B (1970) Electron paramagnetic resonance of transition ions. Oxford University Press, Oxford
- (1970) Electron Paramagnetic Resonance of Transition Ions
- Abragam, A.¹ Bleaney, B.²

58
- 0003431029
- 2 Wiley Hoboken
- Weil JA, Bolton JR (2007) Electron paramagnetic resonance: elementary theory and practical applications, 2nd edn. Wiley, Hoboken
- (2007) Electron Paramagnetic Resonance: Elementary Theory and Practical Applications
- Weil, J.A.¹ Bolton, J.R.²

59
- 0000522059
- 10.1021/ic00273a018 1:CAS:528:DyaL2sXmsVyqtbc%3D
- BK Keppler W Rupp UM Juhl H Endres R Niebl W Balzer 1987 Inorg Chem 26 4366 4370 10.1021/ic00273a018 1:CAS:528:DyaL2sXmsVyqtbc%3D
- (1987) Inorg Chem , vol.26 , pp. 4366-4370
- Keppler, B.K.¹ Rupp, W.² Juhl, U.M.³ Endres, H.⁴ Niebl, R.⁵ Balzer, W.⁶

60
- 0030477371
- Synthesis, characterization and solution chemistry of trans-indazoliumtetrachlorobis(indazole)ruthenate(III), a new anticancer ruthenium complex. IR, UV, NMR, HPLC investigations and antitumor activity
- DOI 10.1155/MBD.1996.243
- K-G Lipponer E Vogel BK Keppler 1996 Met Based Drugs 3 243 260 10.1155/MBD.1996.243 1:CAS:528:DyaK2sXnvVyq 18472901 (Pubitemid 27030983)
- (1996) Metal-Based Drugs , vol.3 , Issue.5 , pp. 243-260
- Lipponer, K.-G.¹ Vogel, E.² Keppler, B.K.³

61
- 20144373868
- Mutational analysis of C-lobe ligands of human serum transferrin: Insights into the mechanism of iron release
- DOI 10.1021/bi050015f
- AB Mason PJ Halbrooks NG James SA Connolly JR Larouche VC Smith RTA MacGillivray ND Chasteen 2005 Biochemistry 44 8013 8021 10.1021/bi050015f 1:CAS:528:DC%2BD2MXktVWqtL8%3D 15924420 (Pubitemid 40776662)
- (2005) Biochemistry , vol.44 , Issue.22 , pp. 8013-8021
- Mason, A.B.¹ Halbrooks, P.J.² James, N.G.³ Connolly, S.A.⁴ Larouche, J.R.⁵ Smith, V.C.⁶ MacGillivray, R.T.A.⁷ Chasteen, N.D.⁸

62
- 2342658401
- XSophe-sophe-XeprView®. A computer simulation software suite (v. 1.1.3) for the analysis of continuous wave EPR spectra
- DOI 10.1016/j.jinorgbio.2004.02.003, PII S0162013404000376
- GR Hanson KE Gates CJ Noble M Griffin A Mitchell S Benson 2004 J Inorg Biochem 98 903 916 10.1016/j.jinorgbio.2004.02.003 1:CAS:528: DC%2BD2cXjvVeqsrw%3D 15134936 (Pubitemid 38595290)
- (2004) Journal of Inorganic Biochemistry , vol.98 , Issue.5 , pp. 903-916
- Hanson, G.R.¹ Gates, K.E.² Noble, C.J.³ Griffin, M.⁴ Mitchell, A.⁵ Benson, S.⁶

63
- 37049080190
- Ni Dhubhghaill OM, Hagen WR, Keppler BK, Lipponer K-G, Sadler PJ (1994) J Chem Soc Dalton Trans 3305-3310
- (1994) J Chem Soc Dalton Trans , pp. 3305-3310
- Ni Dhubhghaill, O.M.¹ Hagen, W.R.² Keppler, B.K.³ Lipponer, K.-G.⁴ Sadler, P.J.⁵

64
- 0015866513
- 1:CAS:528:DyaE2cXpsVQ%3D 4358082
- C Mailer CPS Taylor 1973 Biochim Biophys Acta 322 195 203 1:CAS:528:DyaE2cXpsVQ%3D 4358082
- (1973) Biochim Biophys Acta , vol.322 , pp. 195-203
- Mailer, C.¹ Taylor, C.P.S.²

65
- 0032021289
- 5 complexes obtained from the g matrix
- DOI 10.1016/S0010-8545(97)00073-8
- BR McGarvey 1998 Coord Chem Rev 170 75 92 10.1016/S0010-8545(97)00073-8 1:CAS:528:DyaK1cXjsFOitL8%3D (Pubitemid 128094308)
- (1998) Coordination Chemistry Reviews , vol.170 , pp. 75-92
- McGarvey, B.R.¹

66
- 67650119889
- Telser J, Reisner E, Tierney DL, Keppler BK (2009) Private communication
- (2009) Private Communication
- Telser, J.¹ Reisner, E.² Tierney, D.L.³ Keppler, B.K.⁴

67
- 0001249449
- 10.1139/v95-062 1:CAS:528:DyaK2MXmtFCks74%3D
- C Anderson AL Beauchamp 1995 Can J Chem 73 471 482 10.1139/v95-062 1:CAS:528:DyaK2MXmtFCks74%3D
- (1995) Can J Chem , vol.73 , pp. 471-482
- Anderson, C.¹ Beauchamp, A.L.²

68
- 0001861284
- 10.1016/0020-1693(94)04447-4 1:CAS:528:DyaK2MXmsFGlsrg%3D
- J Chatlas R van Eldik BK Keppler 1995 Inorg Chim Acta 233 59 63 10.1016/0020-1693(94)04447-4 1:CAS:528:DyaK2MXmsFGlsrg%3D
- (1995) Inorg Chim Acta , vol.233 , pp. 59-63
- Chatlas, J.¹ Van Eldik, R.² Keppler, B.K.³

69
- 47149102244
- Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: A novel approach for the analysis of anticancer metallodrugs in human serum and plasma
- DOI 10.1002/elps.200780790
- M Groessl CG Hartinger K Polec-Pawlak M Jarosz BK Keppler 2008 Electrophoresis 29 2224 2232 10.1002/elps.200780790 1:CAS:528: DC%2BD1cXnslWmtrw%3D 18512673 (Pubitemid 351972162)
- (2008) Electrophoresis , vol.29 , Issue.10 , pp. 2224-2232
- Groessl, M.¹ Hartinger, C.G.² Polec-Pawlak, K.³ Jarosz, M.⁴ Keppler, B.K.⁵

70
- 0004195403
- Elsevier Amsterdam
- Seddon EA, Seddon KR (1984) The chemistry of ruthenium. Elsevier, Amsterdam
- (1984) The Chemistry of Ruthenium
- Seddon, E.A.¹ Seddon, K.R.²

71
- 37149046076
- 1:CAS:528:DC%2BD28XpsFOqtL8%3D
- M Groessl CG Hartinger A Egger BK Keppler 2006 Met Ions Biol Med 9 111 116 1:CAS:528:DC%2BD28XpsFOqtL8%3D
- (2006) Met Ions Biol Med , vol.9 , pp. 111-116
- Groessl, M.¹ Hartinger, C.G.² Egger, A.³ Keppler, B.K.⁴

72
- 33745763300
- 10.1021/cr040704h 1:CAS:528:DC%2BD28XjtlOis7c%3D 16771448
- AR Timerbaev CG Hartinger SS Aleksenko BK Keppler 2006 Chem Rev 106 2224 2248 10.1021/cr040704h 1:CAS:528:DC%2BD28XjtlOis7c%3D 16771448
- (2006) Chem Rev , vol.106 , pp. 2224-2248
- Timerbaev, A.R.¹ Hartinger, C.G.² Aleksenko, S.S.³ Keppler, B.K.⁴

73
- 0000067876
- 1:CAS:528:DyaK1MXntFWqt7k%3D
- BR McGarvey 1998 Quim Nova 21 206 213 1:CAS:528:DyaK1MXntFWqt7k%3D
- (1998) Quim Nova , vol.21 , pp. 206-213
- McGarvey, B.R.¹

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.