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Volumn 54, Issue 12, 2016, Pages 3126-3135

Prospects for the therapeutic application of sulfated polysaccharides of brown algae in diseases of the cardiovascular system: review

Author keywords

Angiogenesis; atherosclerosis; cardiovascular diseases; fucoidan; inflammation; vasculogenesis

Indexed keywords

BLOOD CLOTTING FACTOR 10A; CD11B ANTIGEN; CD18 ANTIGEN; COMPLEMENT; FATTY ACID BINDING PROTEIN; FREE RADICAL; FUCOIDIN; FUCOIDIN DERIVATIVE; L SELECTIN; MACROPHAGE SCAVENGER RECEPTOR; METALLOPROTEINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PADGEM PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; POLYSACCHARIDE SULFATE; SCAVENGER RECEPTOR; THROMBIN; UNCLASSIFIED DRUG; POLYSACCHARIDE; SULFATE;

EID: 84998636604     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880209.2016.1185444     Document Type: Review
Times cited : (51)

References (128)
  • 3
    • 0036226428 scopus 로고    scopus 로고
    • Endothelial progenitor cells for vascular regeneration
    • Asahara N, Isner JM. 2002. Endothelial progenitor cells for vascular regeneration. J Hematother Stem Cell Res. 11:171–178.
    • (2002) J Hematother Stem Cell Res , vol.11 , pp. 171-178
    • Asahara, N.1    Isner, J.M.2
  • 6
    • 33644799846 scopus 로고    scopus 로고
    • Neovascularization and cardiac repair by bone marrow-derived stem cells
    • Badoff C, Dimmeler S. 2006. Neovascularization and cardiac repair by bone marrow-derived stem cells. Handb Exp Pharmacol. 174:283–298.
    • (2006) Handb Exp Pharmacol , vol.174 , pp. 283-298
    • Badoff, C.1    Dimmeler, S.2
  • 9
    • 0038618955 scopus 로고    scopus 로고
    • Sulfated fucans, fresh perspectives: structures, functions, and biological priperties of sulfated fucans and overview of enzymes active toward this class of polysaccharide
    • Berteau O, Mulloy B. 2003. Sulfated fucans, fresh perspectives:structures, functions, and biological priperties of sulfated fucans and overview of enzymes active toward this class of polysaccharide. Glycobiology. 13:29–40.
    • (2003) Glycobiology , vol.13 , pp. 29-40
    • Berteau, O.1    Mulloy, B.2
  • 11
    • 0028211792 scopus 로고
    • Inhibition of complement activation by natural sulphated polysaccharides (fucans) from brown seaweed
    • Blondin C, Fisher E, Boisson-Vidal C, Kazatchkine M, Jozefonvicz J, 1994. Inhibition of complement activation by natural sulphated polysaccharides (fucans) from brown seaweed. Mol Immunol. 31:247–253.
    • (1994) Mol Immunol , vol.31 , pp. 247-253
    • Blondin, C.1    Fisher, E.2    Boisson-Vidal, C.3    Kazatchkine, M.4    Jozefonvicz, J.5
  • 15
    • 77956485588 scopus 로고    scopus 로고
    • Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer
    • Casu B, Naggi A, Torri G. 2010. Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer. Matrix Biol. 29:442–452.
    • (2010) Matrix Biol , vol.29 , pp. 442-452
    • Casu, B.1    Naggi, A.2    Torri, G.3
  • 16
    • 0041854298 scopus 로고    scopus 로고
    • Low molecular weight fucoidan and heparin enhance the basic fibroblast growth factor-induced tube formation of endothelial cells through heparan sulfate-dependent alpha6 overexpression
    • Chabut D, Fischer AM, Colliec-Jouault S, Laurendeau I, Matou S, Le Bonniec B, Helley D. 2003. Low molecular weight fucoidan and heparin enhance the basic fibroblast growth factor-induced tube formation of endothelial cells through heparan sulfate-dependent alpha6 overexpression. Mol Pharmacol. 64:696–702.
    • (2003) Mol Pharmacol , vol.64 , pp. 696-702
    • Chabut, D.1    Fischer, A.M.2    Colliec-Jouault, S.3    Laurendeau, I.4    Matou, S.5    Le Bonniec, B.6    Helley, D.7
  • 17
    • 1842636835 scopus 로고    scopus 로고
    • Low molecular weight fucoidan promotes FGF-2-induced vascular tube formation by human endothelial cells, with decreased PAI-1 release and ICAM-1 downregulation
    • Chabut D, Fischer AM, Helley D, Colliec S. 2004. Low molecular weight fucoidan promotes FGF-2-induced vascular tube formation by human endothelial cells, with decreased PAI-1 release and ICAM-1 downregulation. Thromb Res. 113:93–95.
    • (2004) . Thromb Res , vol.113 , pp. 93-95
    • Chabut, D.1    Fischer, A.M.2    Helley, D.3    Colliec, S.4
  • 19
    • 52649121282 scopus 로고    scopus 로고
    • Sulfated polysaccharides and immune response: promoter or inhibitor?
    • Chen D, Wu XZ, Wen ZY. 2008. Sulfated polysaccharides and immune response:promoter or inhibitor? Panminerva Med. 50:177–183.
    • (2008) Panminerva Med , vol.50 , pp. 177-183
    • Chen, D.1    Wu, X.Z.2    Wen, Z.Y.3
  • 20
    • 77956822344 scopus 로고    scopus 로고
    • NMR characterization and molecular modeling of fucoidan showing the importance of oligosaccharide branching in its anticomplementary activity
    • Clément MJ, Tissot B, Chevolot L, Adjadj E, Du Y, Curmi PA, Daniel R. 2010. NMR characterization and molecular modeling of fucoidan showing the importance of oligosaccharide branching in its anticomplementary activity. Glycobiology. 20:883–894.
    • (2010) Glycobiology , vol.20 , pp. 883-894
    • Clément, M.J.1    Tissot, B.2    Chevolot, L.3    Adjadj, E.4    Du, Y.5    Curmi, P.A.6    Daniel, R.7
  • 21
    • 84920827627 scopus 로고    scopus 로고
    • Structure and hypolipidaemic activity of fucoidan extracted from brown seaweed Sargassum henslowianum
    • Cuong HD, Thuy TT, Huong TT, Ly BM, Van TT. 2015. Structure and hypolipidaemic activity of fucoidan extracted from brown seaweed Sargassum henslowianum. Nat Prod Res. 29:411–415.
    • (2015) Nat Prod Res , vol.29 , pp. 411-415
    • Cuong, H.D.1    Thuy, T.T.2    Huong, T.T.3    Ly, B.M.4    Van, T.T.5
  • 24
    • 0033946837 scopus 로고    scopus 로고
    • Class A scavenger receptors: Recent advances in elucidation of structure-function relationships and their role in atherosclerosis
    • Daugherty A, Rateri DL, Whitman SC. 2000. Class A scavenger receptors:Recent advances in elucidation of structure-function relationships and their role in atherosclerosis. Curr Opin Cardiovascular Pulm Ren Invest Drugs. 2:223–232.
    • (2000) Curr Opin Cardiovascular Pulm Ren Invest Drugs , vol.2 , pp. 223-232
    • Daugherty, A.1    Rateri, D.L.2    Whitman, S.C.3
  • 25
    • 2942733214 scopus 로고    scopus 로고
    • Role of endothelial dysfunction in atherosclerosis
    • Davignon J, Ganz P. 2004. Role of endothelial dysfunction in atherosclerosis. Circulation. 109:III-27–I32.
    • (2004) Circulation , vol.109 , pp. 27-32
    • Davignon, J.1    Ganz, P.2
  • 27
    • 77954657196 scopus 로고    scopus 로고
    • Suppression of iNOS expression by fucoidan is mediated by regulation of p38 MAPK, JAK/STAT, AP-1 and IRF-1, and depends on up-regulation of scavenger receptor B1 expression in TNF-alpha- and IFN-gamma-stimulated C6 glioma cells
    • Do H, Pyo S, Sohn EH. 2010. Suppression of iNOS expression by fucoidan is mediated by regulation of p38 MAPK, JAK/STAT, AP-1 and IRF-1, and depends on up-regulation of scavenger receptor B1 expression in TNF-alpha- and IFN-gamma-stimulated C6 glioma cells. J Nutr Biochem. 21:671–679.
    • (2010) J Nutr Biochem , vol.21 , pp. 671-679
    • Do, H.1    Pyo, S.2    Sohn, E.H.3
  • 29
    • 77949652786 scopus 로고    scopus 로고
    • MS80, a novel sulfated polysaccharide, inhibits CD40-NF-kappaB pathway via targeting RIP2
    • Du X, Jiang S, Liu H, Xin X, Li J, Geng M, Jiang H. 2010. MS80, a novel sulfated polysaccharide, inhibits CD40-NF-kappaB pathway via targeting RIP2. Mol Cell Biochem. 337:277–285.
    • (2010) Mol Cell Biochem , vol.337 , pp. 277-285
    • Du, X.1    Jiang, S.2    Liu, H.3    Xin, X.4    Li, J.5    Geng, M.6    Jiang, H.7
  • 31
    • 84855374372 scopus 로고    scopus 로고
    • Macrophages and atherosclerosis: pathophysiological and therapeutic aspects
    • Dushkin MI. 2006. Macrophages and atherosclerosis:pathophysiological and therapeutic aspects. Bul SB RAMS. 2:47–55.
    • (2006) Bul SB RAMS , vol.2 , pp. 47-55
    • Dushkin, M.I.1
  • 32
    • 67650735222 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular disease: Novel tools give (free) radical insight
    • Fearon IM, Faux SP. 2009. Oxidative stress and cardiovascular disease:Novel tools give (free) radical insight. J Mol Cell Cardiol 47:372–381.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 372-381
    • Fearon, I.M.1    Faux, S.P.2
  • 33
    • 80054900219 scopus 로고    scopus 로고
    • Therapies from fucoidan; multifunctional marine polymers
    • Fitton JH. 2011. Therapies from fucoidan; multifunctional marine polymers. Mar Drugs. 9:1731–1760.
    • (2011) Mar Drugs , vol.9 , pp. 1731-1760
    • Fitton, J.H.1
  • 34
    • 70449581263 scopus 로고    scopus 로고
    • Effects of polysaccharides enriched in 2,4-disulfated fucose units on coagulation, thrombosis and bleeding. Practical and conceptual implications
    • Fonseca RJ, Santos GR, Mourao PA. 2009. Effects of polysaccharides enriched in 2,4-disulfated fucose units on coagulation, thrombosis and bleeding. Practical and conceptual implications. Thromb Haemost. 102:829–836.
    • (2009) Thromb Haemost , vol.102 , pp. 829-836
    • Fonseca, R.J.1    Santos, G.R.2    Mourao, P.A.3
  • 35
    • 0036137469 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for coronary artery disease
    • Freedman SB, Isner JM. 2002. Therapeutic angiogenesis for coronary artery disease. Ann Intern Med. 136:54–71.
    • (2002) Ann Intern Med , vol.136 , pp. 54-71
    • Freedman, S.B.1    Isner, J.M.2
  • 37
    • 0034307516 scopus 로고    scopus 로고
    • Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: evidence for selectin-dependent and independent mechanisms
    • Frenette PS, Weiss L. 2000. Sulfated glycans induce rapid hematopoietic progenitor cell mobilization:evidence for selectin-dependent and independent mechanisms. Blood. 96:2460–2468.
    • (2000) Blood , vol.96 , pp. 2460-2468
    • Frenette, P.S.1    Weiss, L.2
  • 39
    • 77953509678 scopus 로고    scopus 로고
    • Adipose tissue, inflammation and atherosclerosis
    • Gustafson B. 2010. Adipose tissue, inflammation and atherosclerosis. J Atheroscler Tromb. 17:1–10.
    • (2010) J Atheroscler Tromb , vol.17 , pp. 1-10
    • Gustafson, B.1
  • 41
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: a double-edged sword
    • Hansson GK, Libby P. 2006. The immune response in atherosclerosis:a double-edged sword. Nat Rev Immunol. 6:508–519.
    • (2006) Nat Rev Immunol , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 42
    • 0031741002 scopus 로고    scopus 로고
    • Modulation of lipopolysaccharide-induced monocyte activation by heparin-binding protein and fucoidan
    • Heinzelmann M, Polk HC, Miller FN. 1998. Modulation of lipopolysaccharide-induced monocyte activation by heparin-binding protein and fucoidan. Infect Immun. 66:5842–5847.
    • (1998) Infect Immun , vol.66 , pp. 5842-5847
    • Heinzelmann, M.1    Polk, H.C.2    Miller, F.N.3
  • 44
    • 34447520043 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases
    • Hu JL, Van den Steen PE, Sang QX, Opdenakker G. 2007. Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases. Nat Rev Drug Discov. 6:480–498.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 480-498
    • Hu, J.L.1    Van den Steen, P.E.2    Sang, Q.X.3    Opdenakker, G.4
  • 45
    • 79952155693 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide (LPS)-induced inflammatory responses by Sargassum hemiphyllum sulfated polysaccharide extract in RAW 264.7 macrophage cells
    • Hwang PA, Chien SY, Chan YL, Lu MK, Wu CH, Kong ZL, Wu CJ. 2011. Inhibition of lipopolysaccharide (LPS)-induced inflammatory responses by Sargassum hemiphyllum sulfated polysaccharide extract in RAW 264.7 macrophage cells. J Agric Food Chem. 59:2062–2068.
    • (2011) J Agric Food Chem , vol.59 , pp. 2062-2068
    • Hwang, P.A.1    Chien, S.Y.2    Chan, Y.L.3    Lu, M.K.4    Wu, C.H.5    Kong, Z.L.6    Wu, C.J.7
  • 46
    • 85063657193 scopus 로고    scopus 로고
    • Fucoidan, a ligand of scavenger receptor class a, causes vascular relaxation through a nitric oxide/cGMP-mediated pathway in rat aorta
    • Iesaki T, Takeuchi M, Okano M, Hashimoto R, Kakigi R, Ishii Y, Okada T. 2014. Fucoidan, a ligand of scavenger receptor class a, causes vascular relaxation through a nitric oxide/cGMP-mediated pathway in rat aorta. Atherosclerosis. 235:e36.
    • (2014) Atherosclerosis , vol.235 , pp. e36
    • Iesaki, T.1    Takeuchi, M.2    Okano, M.3    Hashimoto, R.4    Kakigi, R.5    Ishii, Y.6    Okada, T.7
  • 47
    • 84896691624 scopus 로고    scopus 로고
    • Antioxidant activity jf fucose-containing sulfated polysaccharides obtained from Fucus evanescens by different extraction methods
    • Imbs TI, Skriptsova AV, Zvyagintseva TN. 2015. Antioxidant activity jf fucose-containing sulfated polysaccharides obtained from Fucus evanescens by different extraction methods. J Appl Phycol. 27:545–553.
    • (2015) J Appl Phycol , vol.27 , pp. 545-553
    • Imbs, T.I.1    Skriptsova, A.V.2    Zvyagintseva, T.N.3
  • 48
    • 84885622778 scopus 로고    scopus 로고
    • Statin modulation of human T-cell proliferation, IL-1β and IL-17 production, and IFN- γ T cell expression: synergy with conventional immunosuppressive agents
    • Jameel A, Ooi KG, Jeffs NR, Galatowicz G, Lightman SL, Calder VL. 2013. Statin modulation of human T-cell proliferation, IL-1β and IL-17 production, and IFN- γ T cell expression:synergy with conventional immunosuppressive agents. Int J Inflam. 2013:434586.
    • (2013) Int J Inflam , vol.2013 , pp. 434586
    • Jameel, A.1    Ooi, K.G.2    Jeffs, N.R.3    Galatowicz, G.4    Lightman, S.L.5    Calder, V.L.6
  • 49
    • 1642390201 scopus 로고    scopus 로고
    • Matrix metalloproteinases: a review of their structure and role in acute coronary syndrome
    • Jones CB, Sane DC, Herrington DM. 2003. Matrix metalloproteinases:a review of their structure and role in acute coronary syndrome. Cardiovasc Res. 59:812–823.
    • (2003) Cardiovasc Res , vol.59 , pp. 812-823
    • Jones, C.B.1    Sane, D.C.2    Herrington, D.M.3
  • 50
    • 84906100157 scopus 로고    scopus 로고
    • Fucoidan/FGF-2 induces angiogenesis through JNK- and p38-mediated activation of AKT/MMP-2 signalling
    • Kim BS, Park JY, Kang HJ, Kim HJ, Lee J. 2014. Fucoidan/FGF-2 induces angiogenesis through JNK- and p38-mediated activation of AKT/MMP-2 signalling. Biochem Biophys Res Commun. 450:1333–1338.
    • (2014) Biochem Biophys Res Commun , vol.450 , pp. 1333-1338
    • Kim, B.S.1    Park, J.Y.2    Kang, H.J.3    Kim, H.J.4    Lee, J.5
  • 51
    • 77952675861 scopus 로고    scopus 로고
    • Fucoidan, a sulfated polysaccharide, inhibits adipogenesis through the mitogen-activated protein kinase pathway in 3T3-L1 preadipocytes
    • Kim KJ, Lee OH, Lee BJ. 2010. Fucoidan, a sulfated polysaccharide, inhibits adipogenesis through the mitogen-activated protein kinase pathway in 3T3-L1 preadipocytes. Life Sci. 86:791–797.
    • (2010) Life Sci , vol.86 , pp. 791-797
    • Kim, K.J.1    Lee, O.H.2    Lee, B.J.3
  • 53
    • 70349446642 scopus 로고    scopus 로고
    • Inhibitory effects of fucoidan in 3T3-L1 adipocyte differentiation
    • Kim MJ, Chang UJ, Lee JS. 2009. Inhibitory effects of fucoidan in 3T3-L1 adipocyte differentiation. Mar Biotechnol. 11:557–562.
    • (2009) Mar Biotechnol , vol.11 , pp. 557-562
    • Kim, M.J.1    Chang, U.J.2    Lee, J.S.3
  • 54
    • 84998848230 scopus 로고    scopus 로고
    • Vaccines against atherosclerosis: the state of the problem and perspectives
    • Kozlov VA, Dushkin MI, Vereshchagin EI. 2008. Vaccines against atherosclerosis:the state of the problem and perspectives. Cytokines Inflam. 7:8–14.
    • (2008) Cytokines Inflam , vol.7 , pp. 8-14
    • Kozlov, V.A.1    Dushkin, M.I.2    Vereshchagin, E.I.3
  • 55
    • 84861941275 scopus 로고    scopus 로고
    • Synthesis of low molecular weight carbohydrate mimics heparin
    • Krylov VB, Ustyuzhanina NE, Nifant'ev N. 2011. Synthesis of low molecular weight carbohydrate mimics heparin. Bioorg Chem. 37:745–779.
    • (2011) Bioorg Chem , vol.37 , pp. 745-779
    • Krylov, V.B.1    Ustyuzhanina, N.E.2    Nifant'ev, N.3
  • 57
    • 33845995846 scopus 로고    scopus 로고
    • Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1
    • Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D. 2006. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1. J Biol Chem. 281:37844–37852.
    • (2006) J Biol Chem , vol.281 , pp. 37844-37852
    • Lake, A.C.1    Vassy, R.2    Di Benedetto, M.3    Lavigne, D.4    Le Visage, C.5    Perret, G.Y.6    Letourneur, D.7
  • 58
    • 84929774012 scopus 로고    scopus 로고
    • The sulfated polysaccharide fucoidan rescues senescence of endothelial colony-forming cells for ischemic repair
    • Lee JH, Lee SH, Choi SH, Asahara T, Kwon SM. 2015. The sulfated polysaccharide fucoidan rescues senescence of endothelial colony-forming cells for ischemic repair. Stem Cells. 33:1939–1951.
    • (2015) Stem Cells , vol.33 , pp. 1939-1951
    • Lee, J.H.1    Lee, S.H.2    Choi, S.H.3    Asahara, T.4    Kwon, S.M.5
  • 59
    • 40849083373 scopus 로고    scopus 로고
    • Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells
    • Lee NY, Ermakova SP, Zvyagintseva TN, Kang KW, Dong Z, Choi H. 2008. Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells. Food Chem Toxicol. 46:1793–1800.
    • (2008) Food Chem Toxicol , vol.46 , pp. 1793-1800
    • Lee, N.Y.1    Ermakova, S.P.2    Zvyagintseva, T.N.3    Kang, K.W.4    Dong, Z.5    Choi, H.6
  • 60
    • 83455194637 scopus 로고    scopus 로고
    • A polysaccharide isolated from Ecklonia cava fermented by Lactobacillus brevis inhibits the, inflammatory response by suppressing the activation of nuclear factor-κB in lipopolysaccharide-induced RAW 264.7 macrophages
    • Lee WW, Ahn G, Arachchillage JP, Kim YM, Kim SK, Lee BJ, Jeon YJ. 2011. A polysaccharide isolated from Ecklonia cava fermented by Lactobacillus brevis inhibits the, inflammatory response by suppressing the activation of nuclear factor-κB in lipopolysaccharide-induced RAW 264.7 macrophages. J Med Food. 14:1546–1553.
    • (2011) J Med Food , vol.14 , pp. 1546-1553
    • Lee, W.W.1    Ahn, G.2    Arachchillage, J.P.3    Kim, Y.M.4    Kim, S.K.5    Lee, B.J.6    Jeon, Y.J.7
  • 61
    • 77955380692 scopus 로고    scopus 로고
    • Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells
    • Leeper NJ, Hunter AL, Cooke JP. 2010. Stem cell therapy for vascular regeneration:adult, embryonic, and induced pluripotent stem cells. Circulation. 122:517–526.
    • (2010) Circulation , vol.122 , pp. 517-526
    • Leeper, N.J.1    Hunter, A.L.2    Cooke, J.P.3
  • 62
    • 79960839876 scopus 로고    scopus 로고
    • Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response
    • Li C, Gao Y, Xing Y, et al. 2011. Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response. Food Chem Toxicol. 49:2090–2095.
    • (2011) Food Chem Toxicol , vol.49 , pp. 2090-2095
    • Li, C.1    Gao, Y.2    Xing, Y.3
  • 63
    • 3242702218 scopus 로고    scopus 로고
    • Role of glycosaminoglycans in cellular communication
    • Linhardt R, Toida T. 2004. Role of glycosaminoglycans in cellular communication. Acc Chem Res. 37:431–438.
    • (2004) Acc Chem Res , vol.37 , pp. 431-438
    • Linhardt, R.1    Toida, T.2
  • 64
    • 84861818270 scopus 로고    scopus 로고
    • Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells
    • Li C, Gao Y, Xing Y, Zhu H, Shen J, Tian J. 2012. Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells. Phytomedicine. 19:797–803.
    • (2012) Phytomedicine , vol.19 , pp. 797-803
    • Li, C.1    Gao, Y.2    Xing, Y.3    Zhu, H.4    Shen, J.5    Tian, J.6
  • 65
    • 84998808251 scopus 로고    scopus 로고
    • Immunomodulation and antitumor activity of fucoidan from Undaria pinnatifida in vitro
    • Liu XL, Liu DY, Wang YQ, Yang LL, Yang X, Wu R, Zou X. 2010. Immunomodulation and antitumor activity of fucoidan from Undaria pinnatifida in vitro. Chinese J Microecol. 22:1074–1076.
    • (2010) Chinese J Microecol , vol.22 , pp. 1074-1076
    • Liu, X.L.1    Liu, D.Y.2    Wang, Y.Q.3    Yang, L.L.4    Yang, X.5    Wu, R.6    Zou, X.7
  • 66
    • 0040620527 scopus 로고    scopus 로고
    • Glycosyltransferases and glycan structures contributing to the adhesive activities of L-, E- and P-selectin counter-receptors
    • Lowe JB. 2002. Glycosyltransferases and glycan structures contributing to the adhesive activities of L-, E- and P-selectin counter-receptors. Biochem Soc Symp. 69:33–45.
    • (2002) Biochem Soc Symp , vol.69 , pp. 33-45
    • Lowe, J.B.1
  • 68
    • 18844401151 scopus 로고    scopus 로고
    • Therapeutic angiogenesis and vasculogenesis for tissue regeneration
    • Madeddu P. 2005. Therapeutic angiogenesis and vasculogenesis for tissue regeneration. Exp Physiol. 90:315–326.
    • (2005) . Exp Physiol , vol.90 , pp. 315-326
    • Madeddu, P.1
  • 72
    • 77954369889 scopus 로고    scopus 로고
    • Nutraceuticals and prevention of atherosclerosis: focus on omega-3 polyunsaturated fatty acids and Mediterranean diet polyphenols
    • Massaro M, Scoditti E, Carluccio MA, De Caterina R. 2010. Nutraceuticals and prevention of atherosclerosis:focus on omega-3 polyunsaturated fatty acids and Mediterranean diet polyphenols. Cardiovasc Ther. 28:e13–e19.
    • (2010) Cardiovasc Ther , vol.28 , pp. e13-e19
    • Massaro, M.1    Scoditti, E.2    Carluccio, M.A.3    De Caterina, R.4
  • 73
    • 0037092631 scopus 로고    scopus 로고
    • Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro
    • Matou S, Helley D, Chabut D, Fischer AM. 2002. Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro. Thromb Res. 106:213–221.
    • (2002) Thromb Res , vol.106 , pp. 213-221
    • Matou, S.1    Helley, D.2    Chabut, D.3    Fischer, A.M.4
  • 74
    • 23044495371 scopus 로고    scopus 로고
    • Effects of middle molecular weight fucoidans on in vitro and ex vivo angiogenesis of endothelial cells
    • Matsubara K, Xue C, Zhao X, Mori M, Sugawara T, Hirata T. 2005. Effects of middle molecular weight fucoidans on in vitro and ex vivo angiogenesis of endothelial cells. Int J Mol Med. 15:695–699.
    • (2005) Int J Mol Med , vol.15 , pp. 695-699
    • Matsubara, K.1    Xue, C.2    Zhao, X.3    Mori, M.4    Sugawara, T.5    Hirata, T.6
  • 76
    • 1642265920 scopus 로고    scopus 로고
    • Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives
    • Mourao PAS. 2004. Use of sulfated fucans as anticoagulant and antithrombotic agents:future perspectives. Currt Pharm Des. 10:967–981.
    • (2004) Currt Pharm Des , vol.10 , pp. 967-981
    • Mourao, P.A.S.1
  • 77
    • 43049097572 scopus 로고    scopus 로고
    • Effect of controlled release of fibroblast growth factor-2 from chitosan/fucoidan micro complex-hydrogel on in vitro and in vivo vascularization
    • Nakamura S, Nambu M, Ishizuka T, et al. 2008. Effect of controlled release of fibroblast growth factor-2 from chitosan/fucoidan micro complex-hydrogel on in vitro and in vivo vascularization. J Biomed Mater Res A. 85:619–627.
    • (2008) J Biomed Mater Res A , vol.85 , pp. 619-627
    • Nakamura, S.1    Nambu, M.2    Ishizuka, T.3
  • 78
    • 0026187680 scopus 로고
    • The sulfate-content dependence of the anticoagulant activity of a fucan sulfate from the brown seaweed Ecklonia kurome
    • Nishino T, Nagumo T. 1991. The sulfate-content dependence of the anticoagulant activity of a fucan sulfate from the brown seaweed Ecklonia kurome. Carbohydr Res. 214:193–197.
    • (1991) Carbohydr Res , vol.214 , pp. 193-197
    • Nishino, T.1    Nagumo, T.2
  • 80
    • 33749606619 scopus 로고    scopus 로고
    • Fucoidan prevents C epsilon germline transcription and NFkappaB p52 translocation for IgE production in B cells
    • Oomizu S, Yanase Y, Suzuki H, Kameyoshi Y, Hide M. 2006. Fucoidan prevents C epsilon germline transcription and NFkappaB p52 translocation for IgE production in B cells. Biochem Biophys Res Commun. 350:501–507.
    • (2006) Biochem Biophys Res Commun , vol.350 , pp. 501-507
    • Oomizu, S.1    Yanase, Y.2    Suzuki, H.3    Kameyoshi, Y.4    Hide, M.5
  • 81
    • 34547221505 scopus 로고    scopus 로고
    • Understanding the biology of angiogenesis: review of the most important molecular mechanisms
    • Otrocka ZK, Mahfouzb RR, Makarema JA, Shamseddine AI. 2007. Understanding the biology of angiogenesis:review of the most important molecular mechanisms. Blood Cells Mol Dis. 39:212–220.
    • (2007) Blood Cells Mol Dis , vol.39 , pp. 212-220
    • Otrocka, Z.K.1    Mahfouzb, R.R.2    Makarema, J.A.3    Shamseddine, A.I.4
  • 82
    • 79958740022 scopus 로고    scopus 로고
    • Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells
    • Park HY, Han MH, Park C, Jin CY, Kim GY, Choi IW, Kim ND, Nam TJ, Kwon TK, Choi YH. 2011. Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells. Food Chem Toxicol. 49:1745–1752.
    • (2011) Food Chem Toxicol , vol.49 , pp. 1745-1752
    • Park, H.Y.1    Han, M.H.2    Park, C.3    Jin, C.Y.4    Kim, G.Y.5    Choi, I.W.6    Kim, N.D.7    Nam, T.J.8    Kwon, T.K.9    Choi, Y.H.10
  • 83
    • 80052220096 scopus 로고    scopus 로고
    • Fucoidan from marine brown algae inhibits lipid accumulation
    • Park MK, Jung U, Roh C. 2011. Fucoidan from marine brown algae inhibits lipid accumulation. Mar Drugs. 9:1359–1367.
    • (2011) Mar Drugs , vol.9 , pp. 1359-1367
    • Park, M.K.1    Jung, U.2    Roh, C.3
  • 84
    • 0036147718 scopus 로고    scopus 로고
    • The antimitogenic action of the sulphated polysaccharide fucoidan differs from heparin in human vascular smooth muscle cells
    • Patel MK, Mulloy B, Gallagher KL, O'Brien L, Hughes AD. 2002. The antimitogenic action of the sulphated polysaccharide fucoidan differs from heparin in human vascular smooth muscle cells. Thromb Haemost. 87:149–154.
    • (2002) Thromb Haemost , vol.87 , pp. 149-154
    • Patel, M.K.1    Mulloy, B.2    Gallagher, K.L.3    O'Brien, L.4    Hughes, A.D.5
  • 85
    • 84907157742 scopus 로고    scopus 로고
    • Growth factor- and cytokine-stimulated endothelial progenitor cells in post-ischemic cerebral neovascularization
    • Peplow F. 2014. Growth factor- and cytokine-stimulated endothelial progenitor cells in post-ischemic cerebral neovascularization. Neural Regen Re. 9:1425–1429.
    • (2014) Neural Regen Re , vol.9 , pp. 1425-1429
    • Peplow, F.1
  • 86
    • 84920862010 scopus 로고    scopus 로고
    • Sulfated glycans in inflammation
    • Pomin VH. 2015. Sulfated glycans in inflammation. Eur J Med Chem. 92:353–369.
    • (2015) Eur J Med Chem , vol.92 , pp. 353-369
    • Pomin, V.H.1
  • 87
    • 0036197968 scopus 로고    scopus 로고
    • Nitric oxide triggers the expression of proin-flammatory and protective gene products in mesangial cells and the inflamed glomerulus
    • Pfeilschifter J. 2002. Nitric oxide triggers the expression of proin-flammatory and protective gene products in mesangial cells and the inflamed glomerulus. Nephrol Dial Transplant. 17:347–348.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 347-348
    • Pfeilschifter, J.1
  • 88
    • 28544444249 scopus 로고    scopus 로고
    • Glycomics: an integrated systems approach to structure-function relationships of glycans
    • Raman R, Raguram S, Venkataraman G, Paulson JC, Sasisekharan R. 2005. Glycomics:an integrated systems approach to structure-function relationships of glycans. Nature Methods. 2:817–824.
    • (2005) Nature Methods , vol.2 , pp. 817-824
    • Raman, R.1    Raguram, S.2    Venkataraman, G.3    Paulson, J.C.4    Sasisekharan, R.5
  • 89
    • 0034518352 scopus 로고    scopus 로고
    • Fucoidan inhibits smooth muscle cell proliferation and reduces mitogen-activated protein kinase activity
    • Religa P, Kazi M, Thyberg J, Gaciong Z, Swedenborg J, Hedin U. 2000. Fucoidan inhibits smooth muscle cell proliferation and reduces mitogen-activated protein kinase activity. Eur J Vasc Endovasc Surg. 20:419–426.
    • (2000) Eur J Vasc Endovasc Surg , vol.20 , pp. 419-426
    • Religa, P.1    Kazi, M.2    Thyberg, J.3    Gaciong, Z.4    Swedenborg, J.5    Hedin, U.6
  • 92
    • 84866148828 scopus 로고    scopus 로고
    • Immune response to lipoproteins in atherosclerosis
    • Samson S, Mundkur L, Kakkar VV. 2012. Immune response to lipoproteins in atherosclerosis. Cholesterol. 2012:571846
    • (2012) Cholesterol , vol.2012 , pp. 571846
    • Samson, S.1    Mundkur, L.2    Kakkar, V.V.3
  • 95
    • 0005733952 scopus 로고    scopus 로고
    • Heparinoid–active suphated polysaccharides from marine algae as potential blood anticoagulant agents
    • Shanmugam M, Mody K, 2000. Heparinoid–active suphated polysaccharides from marine algae as potential blood anticoagulant agents. Curr Sci. 79:1672–1683.
    • (2000) Curr Sci , vol.79 , pp. 1672-1683
    • Shanmugam, M.1    Mody, K.2
  • 96
    • 84881081059 scopus 로고    scopus 로고
    • Tunable heparan sulfate mimetics for modulating chemokine activity
    • Sheng GJ, Oh YI, Chang SK, Hsieh-Wilson LC. 2013. Tunable heparan sulfate mimetics for modulating chemokine activity. J Am Chem Soc. 135:10898–10901.
    • (2013) J Am Chem Soc , vol.135 , pp. 10898-10901
    • Sheng, G.J.1    Oh, Y.I.2    Chang, S.K.3    Hsieh-Wilson, L.C.4
  • 97
    • 6444222045 scopus 로고    scopus 로고
    • Glycomics: a pathway to a class of new and improved therapeutics
    • Shriver Z, Raguram S, Sasisekharan R. 2004. Glycomics:a pathway to a class of new and improved therapeutics. Nat Rev Drug Discov. 3:863–873.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 863-873
    • Shriver, Z.1    Raguram, S.2    Sasisekharan, R.3
  • 98
    • 34249075408 scopus 로고    scopus 로고
    • Kinetic analysis of heparin and glucan sulfates binding to P-Selectin and its impact on the general understanding of selectin inhibition
    • Simonis D, Fritzsche J, Alban S, Bendas G. 2007. Kinetic analysis of heparin and glucan sulfates binding to P-Selectin and its impact on the general understanding of selectin inhibition. Biochemistry. 46:6156–6164.
    • (2007) Biochemistry , vol.46 , pp. 6156-6164
    • Simonis, D.1    Fritzsche, J.2    Alban, S.3    Bendas, G.4
  • 99
    • 0242606216 scopus 로고    scopus 로고
    • Therapeutic angiogenesis in cardiovascular disease
    • Simons M, Ware JA. 2003. Therapeutic angiogenesis in cardiovascular disease. Nat Rev Drug Discov. 2:863–872.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 863-872
    • Simons, M.1    Ware, J.A.2
  • 101
    • 0036092976 scopus 로고    scopus 로고
    • Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells
    • Sweeney EA, Lortat-Jacob H, Priestley GV, Nakamoto B, Papayannopoulou T. 2002. Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice:involvement in mobilization of stem/progenitor cells. Blood. 99:44–51.
    • (2002) Blood , vol.99 , pp. 44-51
    • Sweeney, E.A.1    Lortat-Jacob, H.2    Priestley, G.V.3    Nakamoto, B.4    Papayannopoulou, T.5
  • 105
    • 84904859099 scopus 로고    scopus 로고
    • Fucoidans from marine algae as potential matrix metalloproteinase inhibitors
    • Thomas NV, Kim SK. 2014. Fucoidans from marine algae as potential matrix metalloproteinase inhibitors. Adv Food Nutr Res. 72:177–193.
    • (2014) Adv Food Nutr Res , vol.72 , pp. 177-193
    • Thomas, N.V.1    Kim, S.K.2
  • 106
    • 0345099499 scopus 로고    scopus 로고
    • Biological properties of sulfated fucans: the potent inhibiting activity of algal fucoidan against the human compliment system
    • Tissot B, Daniel R. 2003. Biological properties of sulfated fucans:the potent inhibiting activity of algal fucoidan against the human compliment system. Glycobiology. 13:29G–30G.
    • (2003) Glycobiology , vol.13 , pp. 29G-30G
    • Tissot, B.1    Daniel, R.2
  • 108
    • 0035253193 scopus 로고    scopus 로고
    • Heparan sulfate: decoding a dynamic multifunctional cell regulator
    • Turnbull J, Powell A, Guimond S. 2001. Heparan sulfate:decoding a dynamic multifunctional cell regulator. Trends Cell Biol. 11:75–82.
    • (2001) Trends Cell Biol , vol.11 , pp. 75-82
    • Turnbull, J.1    Powell, A.2    Guimond, S.3
  • 111
    • 0035173338 scopus 로고    scopus 로고
    • Therapeutic angiogenesis in critical limb and myocardial ischemia
    • Vale PR1, Isner JM, Rosenfield K. 2001. Therapeutic angiogenesis in critical limb and myocardial ischemia. J Interv Cardiol. 14:511–528.
    • (2001) J Interv Cardiol , vol.14 , pp. 511-528
    • Vale, P.R.1    Isner, J.M.2    Rosenfield, K.3
  • 113
    • 33745040961 scopus 로고    scopus 로고
    • Therapeutic applications of glycosaminoglycans
    • Volpi N. 2006. Therapeutic applications of glycosaminoglycans. Curr Med Chem. 13:1799–1810.
    • (2006) Curr Med Chem , vol.13 , pp. 1799-1810
    • Volpi, N.1
  • 114
    • 84875784589 scopus 로고    scopus 로고
    • Marine-derived angiogenesis inhibitors for cancer therapy. Mar
    • Wang YQ, Miao ZH. 2013. Marine-derived angiogenesis inhibitors for cancer therapy. Mar. Mar Drugs. 11:903–933.
    • (2013) Mar Drugs , vol.11 , pp. 903-933
    • Wang, Y.Q.1    Miao, Z.H.2
  • 115
    • 84855987713 scopus 로고    scopus 로고
    • Biological activities and potential industrial applications of fucose rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: a review
    • Wijesinghe W, Jeon Y. 2012. Biological activities and potential industrial applications of fucose rich sulfated polysaccharides and fucoidans isolated from brown seaweeds:a review. Carbohydrate Polymers. 88:13–20.
    • (2012) Carbohydrate Polymers , vol.88 , pp. 13-20
    • Wijesinghe, W.1    Jeon, Y.2
  • 117
    • 84929169754 scopus 로고    scopus 로고
    • Microwave assisted extraction of sulfated polysaccharides (fucoidan) from Ascophyllum nodosum and its antioxidant activity
    • Yuan Y, Macquarrie D. 2015. Microwave assisted extraction of sulfated polysaccharides (fucoidan) from Ascophyllum nodosum and its antioxidant activity. Carbohydrate Polymers 129:101–107.
    • (2015) Carbohydrate Polymers , vol.129 , pp. 101-107
    • Yuan, Y.1    Macquarrie, D.2
  • 118
    • 50949114609 scopus 로고    scopus 로고
    • Acute antihypertensive effects of fucoidan oligosaccharides prepared from Laminaria japonica on renovascular hypertensive rats
    • Xueyan F, Changhu X, Yan N, Zhaojie L, Jiachao X. 2004. Acute antihypertensive effects of fucoidan oligosaccharides prepared from Laminaria japonica on renovascular hypertensive rats. J Ocean Univ China (Nat Sci) 34:560–564.
    • (2004) J Ocean Univ China (Nat Sci) , vol.34 , pp. 560-564
    • Xueyan, F.1    Changhu, X.2    Yan, N.3    Zhaojie, L.4    Jiachao, X.5
  • 119
    • 0031559902 scopus 로고    scopus 로고
    • The lysine cluster in the collagen-like domain of the scavenger receptor provides for its ligand binding and ligand specificity
    • Yamomoto K, Nishimura N, Doi T, Imanishi T, Suzuki K, Tanaka T. 1997. The lysine cluster in the collagen-like domain of the scavenger receptor provides for its ligand binding and ligand specificity. FEBS Lett 414:182–184.
    • (1997) FEBS Lett , vol.414 , pp. 182-184
    • Yamomoto, K.1    Nishimura, N.2    Doi, T.3    Imanishi, T.4    Suzuki, K.5    Tanaka, T.6
  • 120
    • 0033373335 scopus 로고    scopus 로고
    • Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migration
    • Yang J, Hirata T, Croce K, Merrill-Skoloff G, Tchernychev B, Williams E, Flaumenhaft R, Furie BC, Furie B. 1999. Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migration. J Exp Med. 190:1769–1782.
    • (1999) J Exp Med , vol.190 , pp. 1769-1782
    • Yang, J.1    Hirata, T.2    Croce, K.3    Merrill-Skoloff, G.4    Tchernychev, B.5    Williams, E.6    Flaumenhaft, R.7    Furie, B.C.8    Furie, B.9
  • 121
    • 62749119808 scopus 로고    scopus 로고
    • Increased effect of fucoidan on lipoprotein lipase secretion in adipocytes
    • Yokota T, Nagashima M, Ghazizadeh M, Kawanami O. 2009. Increased effect of fucoidan on lipoprotein lipase secretion in adipocytes. Life Sci 84:523–529.
    • (2009) Life Sci , vol.84 , pp. 523-529
    • Yokota, T.1    Nagashima, M.2    Ghazizadeh, M.3    Kawanami, O.4
  • 123
    • 84998784917 scopus 로고    scopus 로고
    • Cardioprotective effects of fucoidan against hypoxia-induced apoptosis in H9c2 cardiomyoblast cells
    • Zhang SM, Xie ZP, Xu ML, Shi LF. 2015a. Cardioprotective effects of fucoidan against hypoxia-induced apoptosis in H9c2 cardiomyoblast cells. Pharm Biol. 15:1–6.
    • (2015) Pharm Biol , vol.15 , pp. 1-6
    • Zhang, S.M.1    Xie, Z.P.2    Xu, M.L.3    Shi, L.F.4
  • 124
    • 84925868693 scopus 로고    scopus 로고
    • Fucoidan from Macrocystis pyrifera has powerful immune-modulatory effects compared to three other fucoidans
    • Zhang W, Oda T, Yu Q, Jin JO. 2015b. Fucoidan from Macrocystis pyrifera has powerful immune-modulatory effects compared to three other fucoidans. Mar Drugs. 13:1084–1104.
    • (2015) Mar Drugs , vol.13 , pp. 1084-1104
    • Zhang, W.1    Oda, T.2    Yu, Q.3    Jin, J.O.4
  • 125
    • 84925878421 scopus 로고    scopus 로고
    • Structural analysis and anti-complement activity of polysaccharides from Kjellmaniella crsaaifolia
    • Zhang W, Jin W, Sun D, Zhao L, Wang J, Duan D, Zhang Q. 2015c. Structural analysis and anti-complement activity of polysaccharides from Kjellmaniella crsaaifolia. Mar Drugs. 13:1360–1374.
    • (2015) Mar Drugs , vol.13 , pp. 1360-1374
    • Zhang, W.1    Jin, W.2    Sun, D.3    Zhao, L.4    Wang, J.5    Duan, D.6    Zhang, Q.7
  • 127
    • 0036839560 scopus 로고    scopus 로고
    • CD11b/CD18-dependent interactions of neutrophils with intestinal epithelium are mediated by fucosylated proteoglycans
    • Zen K, Liu Y, Cairo D, Parcos CA. 2002. CD11b/CD18-dependent interactions of neutrophils with intestinal epithelium are mediated by fucosylated proteoglycans. J Immunol. 169:5270–5278.
    • (2002) J Immunol , vol.169 , pp. 5270-5278
    • Zen, K.1    Liu, Y.2    Cairo, D.3    Parcos, C.A.4


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