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Volumn 24, Issue 12, 2014, Pages 1265-1274

Fucoidans: Pro- or antiangiogenic agents?

Author keywords

Angiogenesis; FGF; Fucoidan; Structure; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; FUCOIDIN; PROTEOHEPARAN SULFATE; POLYSACCHARIDE;

EID: 84908050703     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwu063     Document Type: Review
Times cited : (94)

References (107)
  • 2
    • 80054996661 scopus 로고    scopus 로고
    • Important determinants for fucoidan bioactivity: A critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds
    • Ale MT, Mikkelsen JD, Meyer AS. 2011. Important determinants for fucoidan bioactivity: A critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds. Mar Drugs. 9: 2106-2130.
    • (2011) Mar Drugs , vol.9 , pp. 2106-2130
    • Ale, M.T.1    Mikkelsen, J.D.2    Meyer, A.S.3
  • 3
    • 0038618955 scopus 로고    scopus 로고
    • Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide
    • Berteau O, Mulloy B. 2003. Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide. Gl ycobiology. 13:29R-40R.
    • (2003) Gl Ycobiology , vol.13 , pp. 29R-40R
    • Berteau, O.1    Mulloy, B.2
  • 4
    • 84902611704 scopus 로고    scopus 로고
    • Sulfated polysaccharides of marine algae-modifiers of function of innate immunity on bacterial, viral and pa rasitic infections
    • (in Russian)
    • Besednova NN, Zaporozhets TS, Makarenkova ID, Ermakova SP, Zvyagintseva TN. 2011. Sulfated polysaccharides of marine algae-Modifiers of function of innate immunity on bacterial, viral and pa rasitic infections. Uspekhi Sovr Biol. 131:503-517 (in Russian).
    • (2011) Uspekhi Sovr Biol , vol.131 , pp. 503-517
    • Besednova, N.N.1    Zaporozhets, T.S.2    Makarenkova, I.D.3    Ermakova, S.P.4    Zvyagintseva, T.N.5
  • 5
    • 77956404514 scopus 로고    scopus 로고
    • Further studies on the composition and structur e of a fucoidan preparation from the brown alga saccharina latissima
    • Bilan MI, Grachev AA, Shashkov AS, Kelly M, Sanderson CJ, Nifantiev NE, Usov AI. 2010. Further studies on the composition and structur e of a fucoidan preparation from the brown alga Saccharina latissima. Carbohydr Res. 345:2038-2047.
    • (2010) Carbohydr Res , vol.345 , pp. 2038-2047
    • Bilan, M.I.1    Grachev, A.A.2    Shashkov, A.S.3    Kelly, M.4    Sanderson, C.J.5    Nifantiev, N.E.6    Usov, A.I.7
  • 10
    • 84901651405 scopus 로고    scopus 로고
    • Structure of a sulfated xylofucan from the brown alga punctaria plantaginea
    • Bilan MI, Shashkov AS, Usov AI. 2014. Structure of a sulfated xylofucan from the brown alga Punctaria plantaginea. Carbohydr Res. 393:1-8.
    • (2014) Carbohydr Res , vol.393 , pp. 1-8
    • Bilan, M.I.1    Shashkov, A.S.2    Usov, A.I.3
  • 11
    • 73349132434 scopus 로고    scopus 로고
    • Structural analysis of fucoidans
    • Bilan MI, Usov AI. 2008. Structural analysis of fucoidans. Nat Prod Commun. 3:1639-1648.
    • (2008) Nat Prod Commun , vol.3 , pp. 1639-1648
    • Bilan, M.I.1    Usov, A.I.2
  • 13
    • 33847296319 scopus 로고    scopus 로고
    • Polysaccharides of algae. 60. Fucoidan from the pacific brown alga analipus japonicus (harv.) winne (ectocarpales, scytosiphonaceae)
    • Bilan MI, Zakharova A N, Grachev AA, Shashkov AS, Nifantiev NE, Usov AI. 2007. Polysaccharides of algae. 60. Fucoidan from the Pacific brown alga Analipus japonicus (Harv.) Winne (Ectocarpales, Scytosiphonaceae). Russ J Bioorg Chem. 33:38-46.
    • (2007) Russ J Bioorg Chem , vol.33 , pp. 38-46
    • Bilan, M.I.1    Zakharova, A.N.2    Grachev, A.A.3    Shashkov, A.S.4    Nifantiev, N.E.5    Usov, A.I.6
  • 15
    • 77958161326 scopus 로고    scopus 로고
    • Heparin as an inhibitor of cancer progression
    • Borsig L. 2010. Heparin as an inhibitor of cancer progression. Prog Mol Biol Transl Sci. 93:335-349.
    • (2010) Prog Mol Biol Transl Sci , vol.93 , pp. 335-349
    • Borsig, L.1
  • 16
    • 84876372433 scopus 로고    scopus 로고
    • Cooperative heparinmediated oligomerization of fibroblast growth factor-1 (fgf1) precedes recruitment of f gfr2 to ternary complexes
    • Brown A, Robinson CJ, Gallagher JT, Blundell TL. 2013. Cooperative heparinmediated oligomerization of fibroblast growth factor-1 (FGF1) precedes recruitment of F GFR2 to ternary complexes. Biophys J. 104:1720-1730.
    • (2013) Biophys J , vol.104 , pp. 1720-1730
    • Brown, A.1    Robinson, C.J.2    Gallagher, J.T.3    Blundell, T.L.4
  • 17
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. 2000. Angiogenesis in cancer and other diseases. Nature. 407(6801):249-257.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 18
    • 77956485588 scopus 로고    scopus 로고
    • Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer
    • Casu B, Naggi A, T orri G. 2010. Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer. Matrix Biol. 29:442-452.
    • (2010) Matrix Biol , vol.29 , pp. 442-452
    • Casu, B.1    Naggi, A.2    Orri G, T.3
  • 19
    • 0041854298 scopus 로고    scopus 로고
    • Low molecular weight fucoidan and heparin enhance the basic fibroblast growth factor-induced tube formation of endothelial cells through heparan sulfate-dependent alpha6 overexpression
    • Chabout D, Fischer AM, Colliec-Jouault S, Laurendeau I, Matou S, Le Bonniec B, Helley D. 2003. Low molecular weight fucoidan and heparin enhance the basic fibroblast growth factor-induced tube formation of endothelial cells through heparan sulfate-dependent alpha6 overexpression. Mol P harmacol. 64:696-702.
    • (2003) Mol Pharmacol , vol.64 , pp. 696-702
    • Chabout, D.1    Fischer, A.M.2    Colliec-Jouault, S.3    Laurendeau, I.4    Matou, S.5    Le Bonniec, B.6    Helley, D.7
  • 20
    • 39449090403 scopus 로고    scopus 로고
    • Characterization of a fucoidan from lessonia vadosa (phaeophyta) and its anticoagulant and elicitor properties
    • Chandia NP, Matsuhiro B. 2008. Characterization of a fucoidan from Lessonia vadosa (Phaeophyta) and its anticoagulant and elicitor properties. Int J Biol Macromol. 42:235-240.
    • (2008) Int J Biol Macromol , vol.42 , pp. 235-240
    • Chandia, N.P.1    Matsuhiro, B.2
  • 21
    • 0035961371 scopus 로고    scopus 로고
    • A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae
    • Chevolot L, Mulloy B, Ratiskol J, Foucault A, Colliec-Jouault S. 2001. A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae. Carbohydr Res. 330:529-535.
    • (2001) Carbohydr Res , vol.330 , pp. 529-535
    • Chevolot, L.1    Mulloy, B.2    Ratiskol, J.3    Foucault, A.4    Colliec-Jouault, S.5
  • 23
    • 0002464983 scopus 로고
    • Fucoidin. Part II. Hydrolysis of a methylated fucoidin prepared from fucus vesiculosus
    • Conchie J, Percival EGV. 1950. Fucoidin. Part II. Hydrolysis of a methylated fucoidin prepared from Fucus vesiculosus. J. Chem. Soc. 827-832.
    • (1950) J. Chem. Soc , pp. 827-832
    • Conchie, J.1    Percival, E.G.V.2
  • 25
    • 41149139565 scopus 로고    scopus 로고
    • Oligosaccharides as anti-Angiogenic agents
    • Cole CL, Jayson GC. 2008. Oligosaccharides as anti-Angiogenic agents. Expert Opin Biol Ther. 8:351-362.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 351-362
    • Cole, C.L.1    Jayson, G.C.2
  • 29
    • 84896754447 scopus 로고    scopus 로고
    • Fucoidan reduces secretion and expression of vascular endothelial growth factor in the retinal pigment epithelium and reduces angiogenesis in vitro
    • Dithmer M, Fuchs S, Shi Y, Schmidt H, Richert E, Roider J, Klettner A. 2014. Fucoidan reduces secretion and expression of vascular endothelial growth factor in the retinal pigment epithelium and reduces angiogenesis in vitro. PLoS ONE. 9:e89150. doi: 10.1371/journal.pone.0089150
    • (2014) PLoS ONE , vol.9 , pp. e89150
    • Dithmer, M.1    Fuchs, S.2    Shi, Y.3    Schmidt, H.4    Richert, E.5    Roider, J.6    Klettner, A.7
  • 30
    • 0035913184 scopus 로고    scopus 로고
    • Structural studies on fucoidans from the brown seaweed sargassum stenophyllum
    • Duarte MER,Cardoso MA,Noseda MD,Cerezo AS 2001 Structural studies on fucoidans from the brown seaweed Sargassum stenophyllum Carbohydr Res. 333 281-293.
    • (2001) Carbohydr Res , vol.333 , pp. 281-293
    • Duarte, M.E.R.1    Cardoso, M.A.2    Noseda, M.D.3    Cerezo, A.S.4
  • 31
    • 80054900219 scopus 로고    scopus 로고
    • Therapies from fucoidan; Multifunctional marine polymers
    • Fitton JH. 2011. Therapies from fucoidan; multifunctional marine polymers. Mar Drugs. 9:1731-1760.
    • (2011) Mar Drugs , vol.9 , pp. 1731-1760
    • Fitton, J.H.1
  • 32
    • 57349089536 scopus 로고    scopus 로고
    • Toxicological evaluation of fucoidan from cladosiphon okamuranus
    • Gideon TP, Rengasamy R. 2 008. Toxicological evaluation of fucoidan from Cladosiphon okamuranus. J Med Food. 11:638-642.
    • (2008) J Med Food , vol.11 , pp. 638-642
    • Gideon, T.P.1    Rengasamy, R.2
  • 35
    • 33747502160 scopus 로고    scopus 로고
    • St ructure and antiviral activity of the galactofucan sulfates extracted from undaria pinnatifida (phaeophyta)
    • Hemmingson JA, Falshaw R, Furneaux RH, Thompson K. 2006. St ructure and antiviral activity of the galactofucan sulfates extracted from Undaria pinnatifida (Phaeophyta). J Appl Phycol. 18:185-193.
    • (2006) J Appl Phycol , vol.18 , pp. 185-193
    • Hemmingson, J.A.1    Falshaw, R.2    Furneaux, R.H.3    Thompson, K.4
  • 36
    • 58549097653 scopus 로고    scopus 로고
    • Fucoidans and fucoida nases-focus on techniques for molecular structure elucidation and modification of marine polysaccharides
    • Holtkamp AD, Kelly S, Ulber R, Lang S. 2009. Fucoidans and fucoida nases-Focus on techniques for molecular structure elucidation and modification of marine polysaccharides. Appl Microbiol Biotechnol. 82:1-11.
    • (2009) Appl Microbiol Biotechnol , vol.82 , pp. 1-11
    • Holtkamp, A.D.1    Kelly, S.2    Ulber, R.3    Lang, S.4
  • 37
    • 84897426924 scopus 로고    scopus 로고
    • Structural investigation and immunological activity of a heteropolysaccharide from sargassum fusiforme
    • Hu P, Xue R, Li Z, Chen M, Sun Z, Jiang J, Huang C. 2014. Structural investigation and immunological activity of a heteropolysaccharide from Sargassum fusiforme. Carbohydr Res. 390:28-32.
    • (2014) Carbohydr Res , vol.390 , pp. 28-32
    • Hu, P.1    Xue, R.2    Li, Z.3    Chen, M.4    Sun, Z.5    Jiang, J.6    Huang, C.7
  • 38
    • 77953121878 scopus 로고    scopus 로고
    • Effect of sulfated fucan, ascophyllan, from the brown alga ascophyllum nodosum on various cell lines: A comparative study on ascophyllan and fucoidan
    • Jiang Z, Okimura T, Yokose T, Yamasaki Y, Yamaguchi K, Oda T. 2010. Effect of sulfated fucan, ascophyllan, from the brown alga Ascophyllum nodosum on various cell lines: A comparative study on ascophyllan and fucoidan. J Biosci Bioeng. 110:113-117.
    • J Biosci Bioeng , vol.2010 , Issue.110 , pp. 113-117
    • Jiang, Z.1    Okimura, T.2    Yokose, T.3    Yamasaki, Y.4    Yamaguchi, K.5    Oda, T.6
  • 39
    • 84883644769 scopus 로고    scopus 로고
    • Importance of sulfate groups for the macrophage-stimulating activities of ascophyllan isolated from the brown alga ascophyllum nodosum
    • Jiang Z, Ueno M, Nishiguchi T, Abu R, Isaka S, Okimura T, Yamaguchi K, Oda T. 2013. Importance of sulfate groups for the macrophage-stimulating activities of ascophyllan isolated from the brown alga Ascophyllum nodosum. Carbohydr Res. 380:124-129 .
    • (2013) Carbohydr Res , vol.380 , pp. 124-129
    • Jiang, Z.1    Ueno, M.2    Nishiguchi, T.3    Abu, R.4    Isaka, S.5    Okimura, T.6    Yamaguchi, K.7    Oda, T.8
  • 40
    • 79851484446 scopus 로고    scopus 로고
    • Chemical structures and bioactivities of sulfated polysaccharides from marine algae
    • Jiao G, Yu G, Zhang J, Ewart HS. 2011. Chemical structures and bioactivities of sulfated polysaccharides from marine algae. Mar Drugs. 9:196-223.
    • (2011) Mar Drugs , vol.9 , pp. 196-223
    • Jiao, G.1    Yu, G.2    Zhang, J.3    Ewart, H.S.4
  • 41
    • 0002608771 scopus 로고    scopus 로고
    • Synthesis, nmr and conformational studies of fucoidan fragments 1: Desulfated 2,3-And 3,4-branched trisaccharide fragments and constituting disaccharides
    • Khatuntseva EA, Ustuzhanina NE, Zatonski i GV, Shashkov AS, Usov AI, Nifant'ev NE. 2000. Synthesis, NMR and conformational studies of fucoidan fragments 1: Desulfated 2,3-And 3,4-branched trisaccharide fragments and constituting disaccharides. J Carbohydr Chem. 19 :1151-1167.
    • (2000) J Carbohydr Chem , vol.19 , pp. 1151-1167
    • Khatuntseva, E.A.1    Ustuzhanina, N.E.2    Zatonskii, G.V.3    Shashkov, A.S.4    Usov, A.I.5    Nifant'Ev, N.E.6
  • 43
    • 0037437728 scopus 로고    scopus 로고
    • Oversulfation of fucoidan enhances its anti-Angiogenic and antitumor activities
    • Koyanagi S, Tanigawa N, Nakagawa H, Soeda S, Shimeno H. 2003. Oversulfation of fucoidan enhances its anti-Angiogenic and antitumor activities. Biochem Pharmacol. 65:173-179.
    • (2003) Biochem Pharmacol , vol.65 , pp. 173-179
    • Koyanagi, S.1    Tanigawa, N.2    Nakagawa, H.3    Soeda, S.4    Shimeno, H.5
  • 48
    • 84896717589 scopus 로고    scopus 로고
    • Fucoidan as a marine anticancer agent in preclinical development
    • Kwak JY. 2014. Fucoidan as a marine anticancer agent in preclinical development. Mar Drugs. 12:851-870.
    • (2014) Mar Drugs , vol.12 , pp. 851-870
    • Kwak, J.Y.1
  • 49
    • 33845995846 scopus 로고    scopus 로고
    • Low molecular weight fucoidan increases vegf165-induced endothelial cell migration by enhancing vegf165 binding to vegfr-2 and nrp1
    • Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D. 2006. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1. J Biol Chem. 28 1:37844-37852.
    • (2006) J Biol Chem , vol.281 , pp. 37844-37852
    • Lake, A.C.1    Vassy, R.2    Di Benedetto, M.3    Lavigne, D.4    Le Visage, C.5    Perret, G.Y.6    Letourneur, D.7
  • 50
    • 0004447619 scopus 로고
    • Sulphated polysaccharides in brown algae. I. Isolation and preliminary characterization of three sulphated polysaccharides from ascophyllum nodosum (l.) le jol
    • Larsen B, Haug A, Painter TJ. 1966. Sulphated polysaccharides in brown algae. I. Isolation and preliminary characterization of three sulphated polysaccharides from Ascophyllum nodosum (L.) Le Jol. Acta Chem Scand. 20:219-230.
    • (1966) Acta Chem Scand , vol.20 , pp. 219-230
    • Larsen, B.1    Haug, A.2    Painter, T.J.3
  • 51
    • 0014911268 scopus 로고
    • Sulphated polysaccharides in brown algae. III. The native state of fucoidan in ascophyllum nodosum and fucus vesiculosus
    • Larsen B,Haug A,Painter TJ 1970 Sulphated polysaccharides in brown algae. III. The native state of fucoidan in Ascophyllum nodosum and Fucus vesiculosus. Acta Chem Scand. 24 3339-3352.
    • (1970) Acta Chem Scand , vol.24 , pp. 3339-3352
    • Larsen, B.1    Haug, A.2    Painter, T.J.3
  • 52
    • 16644376647 scopus 로고    scopus 로고
    • Novel antiviral fucoidan from sporophyll of undaria pinnatifida (mekabu)
    • Lee JB, Hayashi K, Hashimoto M, Nakano T, Hayashi T. 2004. Novel antiviral fucoidan from sporophyll of Undaria pinnatifida (Mekabu). Chem Pharm Bull. 52:1091-1094.
    • (2004) Chem Pharm Bull , vol.52 , pp. 1091-1094
    • Lee, J.B.1    Hayashi, K.2    Hashimoto, M.3    Nakano, T.4    Hayashi, T.5
  • 54
    • 50949098274 scopus 로고    scopus 로고
    • Fucoidan: Structure and bioactivity
    • Li B, Lu F, Wei X, Zhao R. 2008. Fucoidan: Structure and bioactivity. Molecules. 13:1671-1695.
    • (2008) Molecules , vol.13 , pp. 1671-1695
    • Li, B.1    Lu, F.2    Wei, X.3    Zhao, R.4
  • 55
    • 33646522690 scopus 로고    scopus 로고
    • Structural investigation of a fucoidan containing a fucose-free core from the brown seaweed, hizikia fusiforme
    • Li B, Wei XJ, Sun JL, Xu SY. 2006. Structural investigation of a fucoidan containing a fucose-free core from the brown seaweed, Hizikia fusiforme. Carbohydr Res. 341:1135-1146.
    • (2006) Carbohydr Res , vol.341 , pp. 1135-1146
    • Li, B.1    Wei, X.J.2    Sun, J.L.3    Xu, S.Y.4
  • 56
    • 12844262857 scopus 로고    scopus 로고
    • Toxicological evaluation of fucoidan extracted from laminaria japonica inwistar rats
    • Li N, Zhang Q, Song J. 2005. Toxicological evaluation of fucoidan extracted from Laminaria japonica inWistar rats. Food Chem Toxicol. 43:421-426.
    • (2005) Food Chem Toxicol , vol.43 , pp. 421-426
    • Li, N.1    Zhang, Q.2    Song, J.3
  • 57
    • 84861818270 scopus 로고    scopus 로고
    • Fucoidan extract derived from undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells
    • Liu F, Wang J, Chang AK, Liu B, Yan g L, Li Q, Wang P, Zou X. 2012. Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells. Phytomedicine. 19:797-803.
    • (2012) Phytomedicine , vol.19 , pp. 797-803
    • Liu, F.1    Wang, J.2    Chang, A.K.3    Liu, B.4    Yang, L.5    Li, Q.6    Wang, P.7    Zou, X.8
  • 59
    • 84862815238 scopus 로고    scopus 로고
    • Comparison of the effects of marchantin c and fucoidan on sflt-1 and a ngiogenesis in glioma microenvironment
    • Lv Y, Song Q, Shao Q, Gao W, Mao H, Lou H, Qu X, Li X. 2012. Comparison of the effects of marchantin C and fucoidan on sFlt-1 and a ngiogenesis in glioma microenvironment. J Pharm Pharmacol. 64:604-609.
    • J Pharm Pharmacol , vol.2012 , Issue.64 , pp. 604-609
    • Lv, Y.1    Song, Q.2    Shao, Q.3    Gao, W.4    Mao, H.5    Lou, H.6    Qu, X.7    Li, X.8
  • 60
    • 0035829321 scopus 로고    scopus 로고
    • A fucoidan fraction from ascophyllum nodosum
    • Marais MF, Joseleau JP. 2001. A fucoidan fraction from Ascophyllum nodosum. Carbohydr Res. 336:155-159.
    • (2001) Carbohydr Res , vol.336 , pp. 155-159
    • Marais, M.F.1    Joseleau, J.P.2
  • 61
    • 0037092631 scopus 로고    scopus 로고
    • Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro
    • Ma tou S, Helley D, Chabut D, Bros A, Fischer AM. 2002. Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro. Thromb Res. 106:213-221.
    • (2002) Thromb Res , vol.106 , pp. 213-221
    • Matou, S.1    Helley, D.2    Chabut, D.3    Bros, A.4    Fischer, A.M.5
  • 62
    • 23044495371 scopus 로고    scopus 로고
    • Effects of middle molecular weight fucoidans on in vitro and ex vivo angiogenesis of endothelial cells
    • Matsubara K, Xue C, Zhao X, Mori M, Sugawara T, Hirata T. 2005. Effects of middle molecular weight fucoidans on in vitro and ex vivo angiogenesis of endothelial cells. Int J Mol Med. 15:695-699.
    • (2005) Int J Mol Med , vol.15 , pp. 695-699
    • Matsubara, K.1    Xue, C.2    Zhao, X.3    Mori, M.4    Sugawara, T.5    Hirata, T.6
  • 63
    • 33745478458 scopus 로고    scopus 로고
    • Cytokines and proteoglycans: An introductory overview
    • Mulloy B, Rider CC. 2006. Cytokines and proteoglycans: An introductory overview. Biochem Soc Trans. 34:409-413.
    • (2006) Biochem Soc Trans , vol.34 , pp. 409-413
    • Mulloy, B.1    Rider, C.C.2
  • 64
    • 1642265920 scopus 로고    scopus 로고
    • Use of sulfated fucans as anticoagulant and antithrombotic agents: Future perspectives
    • Mourã o PAS. 2004. Use of sulfated fucans as anticoagulant and antithrombotic agents: Future perspectives. Curr Pharm Design. 10:967-981.
    • (2004) Curr Pharm Design , vol.10 , pp. 967-981
    • Mourã, O.P.A.S.1
  • 66
    • 85052592429 scopus 로고    scopus 로고
    • Fucan sulfates and their anticoagulant activities
    • In Dumitriu S, editor. New York Marcel Dekker
    • Nagumo T, Nishino T. 1996. Fucan sulfates and their anticoagulant activities. In: Dumitriu S, editor. Polysaccharides in Medicinal Applications. New York: Marcel Dekker. p. 545-574.
    • (1996) Polysaccharides in Medicinal Applications , pp. 545-574
    • Nagumo, T.1    Nishino, T.2
  • 67
    • 0029791908 scopus 로고    scopus 로고
    • Anticoagulant low molecular weight fucans produced by radical process and ion exchange chromatography of high molecular weight fucans extracted from the brown seaweed ascophyllum nodosum
    • Nardella A, Chaubet F, Boisson-Vidal C, Blondin C, Durand P, Jozefonvicz J. 1996. Anticoagulant low molecular weight fucans produced by radical process and ion exchange chromatography of high molecular weight fucans extracted from the brown seaweed Ascophyllum nodosum. Carbohydr Res. 289:201-208.
    • (1996) Carbohydr Res , vol.289 , pp. 201-208
    • Nardella, A.1    Chaubet, F.2    Boisson-Vidal, C.3    Blondin, C.4    Durand, P.5    Jozefonvicz, J.6
  • 68
    • 0026413056 scopus 로고
    • Structural characterization of a new anticoagul ant fucan sulfate from the brown seaweed ecklonia kurome
    • Nishino T, Nagumo T, Kiyohara H, Yamada H. 1991. Structural characterization of a new anticoagul ant fucan sulfate from the brown seaweed Ecklonia kurome. Carbohydr Res. 211:77-90.
    • (1991) Carbohydr Res , vol.211 , pp. 77-90
    • Nishino, T.1    Nagumo, T.2    Kiyohara, H.3    Yamada, H.4
  • 69
    • 0028763775 scopus 로고
    • Isolation and partial characterization of a novel amino sugar-containing fucan sulfate from commercial fucus vesiculosus fucoidan
    • Nishino T, Nishioka C, Ura H, Nagumo T. 1994. Isolation and partial characterization of a novel amino sugar-containing fucan sulfate from commercial Fucus vesiculosus fucoidan. Carbohydr Res. 255:213-224.
    • (1994) Carbohydr Res , vol.255 , pp. 213-224
    • Nishino, T.1    Nishioka, C.2    Ura, H.3    Nagumo, T.4
  • 70
    • 0028062517 scopus 로고
    • Isolation and partial characterization of a novel ?-d-galactan sulfate from the brown seaweed laminaria angustata var. Longissima
    • Nishino T, Takabe Y, Nagumo T. 1994. Isolation and partial characterization of a novel ?-D-galactan sulfate from the brown seaweed Laminaria angustata var. longissima. Carbohydr Polym. 23:165-173.
    • (1994) Carbohydr Polym , vol.23 , pp. 165-173
    • Nishino, T.1    Takabe, Y.2    Nagumo, T.3
  • 71
    • 0001004230 scopus 로고
    • Algal polysaccharides
    • In Aspinall GO editor. New York Academic Press
    • Painter TJ. 1983. Algal polysaccharides. In: Aspinall GO, editor. The Polysaccharides, Vol. 2. New York: Academic Press. p. 195-285.
    • (1983) The Polysaccharides , vol.2 , pp. 195-285
    • Painter, T.J.1
  • 72
    • 0027494436 scopus 로고
    • A revised structure for fucoidan may explain some of its biological activities
    • Patankar MS, Oehninger S, Barnett T, Williams RL, Clark GF. 1993. A revised structure for fucoidan may explain some of its biological activities. J Bi ol Chem. 268:21770-21776.
    • (1993) J Biol Chem , vol.268 , pp. 21770-21776
    • Patankar, M.S.1    Oehninger, S.2    Barnett, T.3    Williams, R.L.4    Clark, G.F.5
  • 74
    • 57149087953 scopus 로고    scopus 로고
    • Structure, biology, evolution, and medical importance of sulfated fucans and galactans
    • Pomin VH, Mourã o PAS. 2008. Structure, biology, evolution, and medical importance of sulfated fucans and galactans. Glycobiology. 18:1016-1027.
    • (2008) Glycobiology , vol.18 , pp. 1016-1027
    • Pomin, V.H.1    Mourã, O.P.A.S.2
  • 75
    • 0347927250 scopus 로고    scopus 로고
    • Fucoidans from the brown seaw eed adenocystis utricularis: Extraction methods, antiviral activity and structural studies
    • Ponce NMA, Pujol CA, Damonte EB, Flores ML, Stortz CA. 2003. Fucoidans from the brown seaw eed Adenocystis utricularis: Extraction methods, antiviral activity and structural studies. Carbohydr Res. 338:153-165.
    • (2003) Carbohydr Res , vol.338 , pp. 153-165
    • Ponce, N.M.A.1    Pujol, C.A.2    Damonte, E.B.3    Flores, M.L.4    Stortz, C.A.5
  • 76
    • 80052933197 scopus 로고    scopus 로고
    • Basic and therapeutic aspects of angiogenesis
    • Potente M, Gerhardt H, Carmeliet P. 2011. Basic and therapeutic aspects of angiogenesis. Cell. 146:873-887.
    • (2011) Cell , vol.146 , pp. 873-887
    • Potente, M.1    Gerhardt, H.2    Carmeliet, P.3
  • 77
    • 0032483520 scopus 로고    scopus 로고
    • Heparan sulfate oligosaccharides require 6-o-sulfation for promotion of basic fibroblast growth factor mitogenic activity
    • Pye DA, Vives RR, Turnbull JE, Hyde P, Gallagher JT. 1998. Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity. J Biol Chem. 273:22936-22942.
    • (1998) J Biol Chem , vol.273 , pp. 22936-22942
    • Pye, D.A.1    Vives, R.R.2    Turnbull, J.E.3    Hyde, P.4    Gallagher, J.T.5
  • 78
    • 13444261932 scopus 로고    scopus 로고
    • The crucial role of vascular permeability factor/vascular endothelial growth factor in angiogenesis: A historical review
    • Ribatti D. 2005. The crucial role of vascular permeability factor/vascular endothelial growth factor in angiogenesis: A historical review. Br J Haematol. 128:303-309.
    • (2005) Br J Haematol , vol.128 , pp. 303-309
    • Ribatti, D.1
  • 79
    • 33644977975 scopus 로고    scopus 로고
    • Vegf165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by k5 lyase
    • Robinson CJ, Mulloy B, Gallagher JT, Stringer SE. 2006. VEGF165-binding sites within heparan sulfate encompass two highly sulfated domains and can be liberated by K5 lyase. J Biol Chem. 281:1731-1740.
    • (2006) J Biol Chem , vol.281 , pp. 1731-1740
    • Robinson, C.J.1    Mulloy, B.2    Gallagher, J.T.3    Stringer, S.E.4
  • 81
    • 0346052506 scopus 로고    scopus 로고
    • Structures of oligosaccharides derived from cladosiphon okamuranus fucoidan by digestion with marine bacterial enzymes
    • Sakai T, Ishizuka K, Shimanaka K, Ikai K, Kato I. 2003. Structures of oligosaccharides derived from Cladosiphon okamuranus fucoidan by digestion with marine bacterial enzymes. Mar Biotechnol. 5:536-544.
    • (2003) Mar Biotechnol , vol.5 , pp. 536-544
    • Sakai, T.1    Ishizuka, K.2    Shimanaka, K.3    Ikai, K.4    Kato, I.5
  • 82
    • 0037218267 scopus 로고    scopus 로고
    • Marine bacterial sulfa ted fucoglucuronomannan (sfgm) lyase digests brown algal sfgm into trisaccharides
    • Sakai T, Kimura H, Kojima K, Shimanaka K, Ikai K, Kato I. 2003. Marine bacterial sulfa ted fucoglucuronomannan (SFGM) lyase digests brown algal SFGM into trisaccharides. Mar Biotechnol. 5:70-78.
    • (2003) Mar Biotechnol , vol.5 , pp. 70-78
    • Sakai, T.1    Kimura, H.2    Kojima, K.3    Shimanaka, K.4    Ikai, K.5    Kato, I.6
  • 86
    • 0034595587 scopus 로고    scopus 로고
    • Oversulfated fucoidan inhibits the basic fibroblast growth factor-induced tube formation by human umbilical vein endothelial cells: Its possible mechanism of action
    • Soeda S, Kozako T, Iwata K, Shimeno H. 2000. Oversulfated fucoidan inhibits the basic fibroblast growth factor-induced tube formation by human umbilical vein endothelial cells: Its possible mechanism of action. Biochim Bi ophys Acta. 1497:127-134.
    • (2000) Biochim Bi Ophys Acta , vol.1497 , pp. 127-134
    • Soeda, S.1    Kozako, T.2    Iwata, K.3    Shimeno, H.4
  • 87
    • 0031390070 scopus 로고    scopus 로고
    • Inhibitory effect of oversulfated fucoidan on tube formation by human vascular endothelial cells
    • Soeda S, Shibata Y, Shimeno H. 1997. Inhibitory effect of oversulfated fucoidan on tube formation by human vascular endothelial cells. Biol Pharm Bull. 20:1131-1135.
    • (1997) Biol Pharm Bull , vol.20 , pp. 1131-1135
    • Soeda, S.1    Shibata, Y.2    Shimeno, H.3
  • 88
    • 33745441066 scopus 로고    scopus 로고
    • The role of heparan sulphate proteoglycans in angiogenesis
    • Stringer S. 2006. The role of heparan sulphate proteoglycans in angiogenesis. Biochem Soc Trans. 34:451-453.
    • (2006) Biochem Soc Trans , vol.34 , pp. 451-453
    • Stringer, S.1
  • 89
    • 77950863237 scopus 로고    scopus 로고
    • Structure and antitumor activity of fucoidan isolated from sporophyll of Korean brown seaweed undaria pinnatifida
    • Synytsya A, KimWJ, Kim SM, Pohl R, Kvasnika F, ?opíkováJ, Park YI. 2010 . Structure and antitumor activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida. Carbohydr Polym. 81:41-48.
    • (2010) Carbohydr Polym , Issue.81 , pp. 41-48
    • Synytsya, A.1    Kim, W.J.2    Kim, S.M.3    Pohl, R.4    Kvasnika, F.5    Opíková, J.6    Park, Y.I.7
  • 90
    • 84869026979 scopus 로고    scopus 로고
    • A review on angiogenesis and its assays
    • Tahergorabi Z, Khazaei M. 2012. A review on angiogenesis and its assays. Iran J Basic Med Sci. 15:1110-1126.
    • (2012) Iran J Basic Med Sci , vol.15 , pp. 1110-1126
    • Tahergorabi, Z.1    Khazaei, M.2
  • 91
    • 70350722239 scopus 로고    scopus 로고
    • Fucoidans-sulfated polysaccharides of brown algae
    • Usov AI, Bilan MI. 2009. Fucoidans-Sulfated polysaccharides of brown algae. Russ Chem Rev. 78:785-799.
    • (2009) Russ Chem Rev , vol.78 , pp. 785-799
    • Usov, A.I.1    Bilan, M.I.2
  • 92
    • 22044455930 scopus 로고    scopus 로고
    • Polysaccharides of algae. 53. Brown alga laminaria saccharina (l.) lam. As a source of fucoidan
    • Usov AI, Smirnova GP, Bilan MI, Shashkov AS. 1998. Polysaccharides of algae. 53. Brown alga Laminaria saccharina (L.) Lam. as a source of fucoidan. Russ J Bioorg Chem. 24:382-389.
    • (1998) Russ J Bioorg Chem , vol.24 , pp. 382-389
    • Usov, A.I.1    Smirnova, G.P.2    Bilan, M.I.3    Shashkov, A.S.4
  • 93
    • 28444488348 scopus 로고    scopus 로고
    • Polysaccharides of algae. 58. The polysaccharide composition of the pacific brown alga alaria fistulosa p. et r. (Alariaceae, laminariales)
    • Usov AI, Smirnova GP, Klochkova NG. 2005 . Polysaccharides of algae. 58. The polysaccharide composition of the Pacific brown alga Alaria fistulosa P. et R. (Alariaceae, Laminariales). Russ Chem Bull Int Ed. 54:1282-1286.
    • (2005) Russ Chem Bull Int Ed , vol.54 , pp. 1282-1286
    • Usov, A.I.1    Smirnova, G.P.2    Klochkova, N.G.3
  • 94
    • 33845633244 scopus 로고    scopus 로고
    • Synthesis nmr and conformational studies of fucoidan fragments. 8. Convergent synthesis of branched and linear oligosaccharides
    • Ustyuzhanina N,Krylov V,Grachev A,Gerbst A,Nifantiev N 2006 Synthesis NMR and conformational studies of fucoidan fragments. 8. Convergent synthesis of branched and linear oligosaccharides Synthesis. 23 4017-4031.
    • (2006) Synthesis , Issue.23 , pp. 4017-4031
    • Ustyuzhanina, N.1    Krylov, V.2    Grachev, A.3    Gerbst, A.4    Nifantiev, N.5
  • 97
    • 81455158705 scopus 로고    scopus 로고
    • Sulfated polysaccharides from brown seaweeds s accharina japonica and undaria pinnatifida: Isolation, structural characteristics, and antitumor activity
    • Vishchuk OS, Ermakova SP, Zvyagintseva TN. 2011. Sulfated polysaccharides from brown seaweeds S accharina japonica and Undaria pinnatifida: Isolation, structural characteristics, and antitumor activity. Carbohydr Res. 345:2769-2776.
    • (2011) Carbohydr Res , vol.345 , pp. 2769-2776
    • Vishchuk, O.S.1    Ermakova, S.P.2    Zvyagintseva, T.N.3
  • 98
    • 38349164399 scopus 로고    scopus 로고
    • Antioxidant activity of sulfated polysaccharide fractions extracted from laminaria japonica
    • Wang J, Zhang Q, Zhang Z, Li Z. 2008. Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica. Int J Biol Macromol. 42:127-132.
    • (2008) Int J Biol Macromol , vol.42 , pp. 127-132
    • Wang, J.1    Zhang, Q.2    Zhang, Z.3    Li, Z.4
  • 99
    • 77954145175 scopus 로고    scopus 로고
    • Structural studies on a novel fucogalact an sulfate extracted from the brown seaweed laminaria japonica
    • Wang J, Zhang Q, Zhang Z, Zhang H, Niu X. 2010. Structural studies on a novel fucogalact an sulfate extracted from the brown seaweed Laminaria japonica. Int J Biol Macromol. 47:126-131.
    • (2010) Int J Biol Macromol , vol.47 , pp. 126-131
    • Wang, J.1    Zhang, Q.2    Zhang, Z.3    Zhang, H.4    Niu, X.5
  • 100
    • 84875784589 scopus 로고    scopus 로고
    • Marine-derived angiogenesis inhibitors for cancer therapy
    • Wang YQ, Miao ZH. 2013. Marine-derived angiogenesis inhibitors for cancer therapy. Mar Drugs. 11:903-933.
    • (2013) Mar Drugs , Issue.11 , pp. 903-933
    • Wang, Y.Q.1    Miao, Z.H.2
  • 101
    • 84855987713 scopus 로고    scopus 로고
    • Biological activities and potential industrial applications of fucose rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: A review
    • Wijesinghe WAJP, Jeon YJ. 2012. Biological activities and potential industrial applications of fucose rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: A review. Carbohydr Polym. 88:13-20.
    • (2012) Carbohydr Polym , vol.88 , pp. 13-20
    • Wajp, W.1    Jeon, Y.J.2
  • 102
    • 0035124240 scopus 로고    scopus 로고
    • Chemical characters and antioxidative properties of sulfated polysaccharides from laminaria japonica
    • Xue CH, Fang Y, Lin H, Chen L, Li ZJ, Deng D, Lu CX. 2001. Chemical characters and antioxidative properties of sulfated polysaccharides from Laminaria japonica. J Appl Phycol. 13:67-70.
    • (2001) J Appl Phycol , vol.13 , pp. 67-70
    • Xue, C.H.1    Fang, Y.2    Lin, H.3    Chen, L.4    Li, Z.J.5    Deng, D.6    Lu, C.X.7
  • 103
    • 84865175152 scopus 로고    scopus 로고
    • Anticancer properties and mechanisms of fucoidan on mouse breast cancer in vitro and in vivo
    • Xue M, Ge Y, Zhang J, Wang Q, Hou L, Liu Y, Sun L, Li Q. 2012. Anticancer properties and mechanisms of fucoidan on mouse breast cancer in vitro and in vivo. PLoS ONE. 7:e43483.
    • (2012) PLoS ONE , vol.7 , pp. e43483
    • Xue, M.1    Ge, Y.2    Zhang, J.3    Wang, Q.4    Hou, L.5    Liu, Y.6    Sun, L.7    Li, Q.8
  • 104
    • 28944446844 scopus 로고    scopus 로고
    • Enzyme-digested fucoidan extracts derived from seaweed mozuku of cladosiphon novae-caledoniae kylin inhibit invasion a nd angiogenesis of tumor cells
    • Ye J, L i Y, Teruya K, Katakura Y, Ichikawa A, Eto H, Hosoi M, Hosoi M, Nishimoto S, Shirahata S. 2005. Enzyme-digested fucoidan extracts derived from seaweed Mozuku of Cladosiphon novae-caledoniae kylin inhibit invasion a nd angiogenesis of tumor cells. Cytotechnology. 47:117-126.
    • (2005) Cytotechnology , vol.47 , pp. 117-126
    • Ye, J.1    Li, Y.2    Teruya, K.3    Katakura, Y.4    Ichikawa, A.5    Eto, H.6    Hosoi, M.7    Hosoi, M.8    Nishimoto, S.9    Shirahata, S.10
  • 105
    • 34548207829 scopus 로고    scopus 로고
    • A sulfated fucan from the brown alga laminaria cichorioides has mainly heparin cofactor II-depend ent anticoagulant activity
    • Yoon SJ, Pyun YR, Hwang JK, Mourão PAS. 2007. A sulfated fucan from the brown alga Laminaria cichorioides has mainly heparin cofactor II-depend ent anticoagulant activity. Carbohydr Res. 342:2326-2330.
    • (2007) Carbohydr Res , vol.342 , pp. 2326-2330
    • Yoon, S.J.1    Pyun, Y.R.2    Hwang, J.K.3    Mourão, P.A.S.4
  • 106
    • 77951667889 scopus 로고    scopus 로고
    • Higher specificity of the activity of low molecular weight fucoidan for thromb in-induced platelet aggregation
    • Zhu Z, Zhang Q, Chen L, Ren S, Xu P, Tang Y, Luo D. 2010. Higher specificity of the activity of low molecular weight fucoidan for thromb in-induced platelet aggregation. Thromb Res. 125:419-426.
    • (2010) Thromb Res , vol.125 , pp. 419-426
    • Zhu, Z.1    Zhang, Q.2    Chen, L.3    Ren, S.4    Xu, P.5    Tang, Y.6    Luo, D.7
  • 107
    • 0042734561 scopus 로고    scopus 로고
    • Water-soluble polysaccharides of some far-eastern bro wn seaweeds. Distribution, structure, and their dependence on the developmental conditions
    • Zvyagintseva TN, Shevchenko NM, Chizhov AO, Krupnova TN, Sundukova EV, Isakov VV. 2003. Water-soluble polysaccharides of some far-eastern bro wn seaweeds. Distribution, structure, and their dependence on the developmental conditions. J Exp Mar Biol Ecol. 294:1-13.
    • (2003) J Exp Mar Biol Ecol , vol.294 , pp. 1-13
    • Zvyagintseva, T.N.1    Shevchenko, N.M.2    Chizhov, A.O.3    Krupnova, T.N.4    Sundukova, E.V.5    Isakov, V.V.6


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