Suppression of iNOS expression by fucoidan is mediated by regulation of p38 MAPK, JAK/STAT, AP-1 and IRF-1, and depends on up-regulation of scavenger receptor B1 expression in TNF-α- and IFN-γ-stimulated C6 glioma cells

Journal of Nutritional Biochemistry

Volumn 21, Issue 8, 2010, Pages 671-679

  Do, Hang ^a   Pyo, Suhkneung ^a   Sohn, Eun Hwa ^b  

^a Sungkyunkwan University   (South Korea)

^b Kangwon National University   (South Korea)

Author keywords

Fucoidan; Glia; INOS; P38; SRB1

Indexed keywords

AP 1 PROTEIN; FUCOIDIN; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; JANUS KINASE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; SCAVENGER RECEPTOR BI; SMALL INTERFERING RNA; STAT PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; GLIOMA CELL; MOLECULAR MECHANICS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BASE SEQUENCE; BRAIN NEOPLASMS; CELL LINE, TUMOR; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GLIOMA; INTERFERON-GAMMA; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POLYSACCHARIDES; RATS; RECEPTORS, SCAVENGER; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 77954657196     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2009.03.013     Document Type: Article

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