Kinetic analysis of heparin and glucan sulfates binding to P-selectin and its impact on the general understanding of selectin inhibition

Biochemistry

Volumn 46, Issue 20, 2007, Pages 6156-6164

  Simonis, Dirk ^a   Fritzsche, Juliane ^a   Alban, Susanne ^b   Bendas, Gerd ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAN SULFATES; HEPARIN; PHYSIOLOGICAL LIGANDS; SELECTIN INHIBITION;

BIOSENSORS; CELL ADHESION; DRUG THERAPY; KINETIC THEORY; PLATELETS; POLYSACCHARIDES; QUARTZ CRYSTAL MICROBALANCES; TUMORS;

DRUG PRODUCTS;

GLUCAN; GLUCAN SULFATE; HEPARIN; HEPARIN CALCIUM; LIQUEMIN N; MONOCLONAL ANTIBODY; PADGEM PROTEIN; POLYSACCHARIDE SULFATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; BIOSENSOR; CELL CULTURE; CELL MOTION; CELL ROLLING; CELL STRAIN U937; CORRELATION ANALYSIS; CULTURE MEDIUM; HUMAN; HUMAN CELL; KINETICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN IMMOBILIZATION; PROTEIN PROTEIN INTERACTION; QUARTZ CRYSTAL MICROBALANCE BIOSENSOR; SULFATION;

BINDING SITES; BIOSENSING TECHNIQUES; CELL ADHESION; CELL MIGRATION INHIBITION; CELL MOVEMENT; GLUCANS; HEPARIN; HUMANS; KINETICS; LIGANDS; MEMBRANE GLYCOPROTEINS; P-SELECTIN; PROTEIN BINDING; PROTEOGLYCANS; QUARTZ; RECOMBINANT PROTEINS; U937 CELLS;

EID: 34249075408     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi602347g     Document Type: Article

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