-
1
-
-
84902993335
-
Estimating the heritability of colorectal cancer
-
Jiao, S., Peters, U., Berndt, S., Brenner, H., Butterbach, K., Caan, B.J., Carlson, C.S., Chan, A.T., Chang-Claude, J., Chanock, S. et al. (2014) Estimating the heritability of colorectal cancer. Hum. Mol. Genet., 23, 3898-3905.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 3898-3905
-
-
Jiao, S.1
Peters, U.2
Berndt, S.3
Brenner, H.4
Butterbach, K.5
Caan, B.J.6
Carlson, C.S.7
Chan, A.T.8
Chang-Claude, J.9
Chanock, S.10
-
2
-
-
84875253066
-
Identification of genetic susceptibility loci for colorectal tumors in a genome-wide metaanalysis
-
Peters, U., Jiao, S., Schumacher, F.R., Hutter, C.M., Aragaki, A.K., Baron, J.A., Berndt, S.I., Bezieau, S., Brenner, H., Butterbach, K. et al. (2013) Identification of genetic susceptibility loci for colorectal tumors in a genome-wide metaanalysis. Gastroenterology, 144, 799-807. e724.
-
(2013)
Gastroenterology
, vol.144
-
-
Peters, U.1
Jiao, S.2
Schumacher, F.R.3
Hutter, C.M.4
Aragaki, A.K.5
Baron, J.A.6
Berndt, S.I.7
Bezieau, S.8
Brenner, H.9
Butterbach, K.10
-
3
-
-
84897427369
-
Architecture of inherited susceptibility to colorectal cancer: A voyage of discovery
-
Whiffin, N. and Houlston, R.S. (2014) Architecture of inherited susceptibility to colorectal cancer: a voyage of discovery. Genes, 5, 270-284.
-
(2014)
Genes
, vol.5
, pp. 270-284
-
-
Whiffin, N.1
Houlston, R.S.2
-
4
-
-
79959851441
-
Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer
-
Tomlinson, I.P., Carvajal-Carmona, L.G., Dobbins, S.E., Tenesa, A., Jones, A.M., Howarth, K., Palles, C., Broderick, P., Jaeger, E.E., Farrington, S. et al. (2011) Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PLoS Genet., 7, e1002105.
-
(2011)
PLoS Genet.
, vol.7
, pp. e1002105
-
-
Tomlinson, I.P.1
Carvajal-Carmona, L.G.2
Dobbins, S.E.3
Tenesa, A.4
Jones, A.M.5
Howarth, K.6
Palles, C.7
Broderick, P.8
Jaeger, E.E.9
Farrington, S.10
-
5
-
-
35648937584
-
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk
-
Broderick, P., Carvajal-Carmona, L., Pittman, A.M., Webb, E., Howarth, K., Rowan, A., Lubbe, S., Spain, S., Sullivan, K., Fielding, S. et al. (2007) A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat. Genet., 39, 1315-1317.
-
(2007)
Nat. Genet.
, vol.39
, pp. 1315-1317
-
-
Broderick, P.1
Carvajal-Carmona, L.2
Pittman, A.M.3
Webb, E.4
Howarth, K.5
Rowan, A.6
Lubbe, S.7
Spain, S.8
Sullivan, K.9
Fielding, S.10
-
6
-
-
84863005628
-
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
-
Dunlop, M.G., Dobbins, S.E., Farrington, S.M., Jones, A.M., Palles, C., Whiffin, N., Tenesa, A., Spain, S., Broderick, P., Ooi, L.Y. et al. (2012) Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat. Genet., 44, 770-776.
-
(2012)
Nat. Genet.
, vol.44
, pp. 770-776
-
-
Dunlop, M.G.1
Dobbins, S.E.2
Farrington, S.M.3
Jones, A.M.4
Palles, C.5
Whiffin, N.6
Tenesa, A.7
Spain, S.8
Broderick, P.9
Ooi, L.Y.10
-
7
-
-
78049353079
-
Meta-analysis of three genomewide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
-
Houlston, R.S., Cheadle, J., Dobbins, S.E., Tenesa, A., Jones, A.M., Howarth, K., Spain, S.L., Broderick, P., Domingo, E., Farrington, S. et al. (2010) Meta-analysis of three genomewide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nat. Genet., 42, 973-977.
-
(2010)
Nat. Genet.
, vol.42
, pp. 973-977
-
-
Houlston, R.S.1
Cheadle, J.2
Dobbins, S.E.3
Tenesa, A.4
Jones, A.M.5
Howarth, K.6
Spain, S.L.7
Broderick, P.8
Domingo, E.9
Farrington, S.10
-
8
-
-
79955564023
-
Intestinal inflammation and cancer
-
Ullman, T.A. and Itzkowitz, S.H. (2011) Intestinal inflammation and cancer. Gastroenterology, 140, 1807-1816.
-
(2011)
Gastroenterology
, vol.140
, pp. 1807-1816
-
-
Ullman, T.A.1
Itzkowitz, S.H.2
-
9
-
-
79961047053
-
Intestinal inflammation and colorectal cancer: A doubleedged sword? World J
-
Rizzo, A., Pallone, F., Monteleone, G. and Fantini, M.C. (2011) Intestinal inflammation and colorectal cancer: a doubleedged sword? World J. Gastroenterol., 17, 3092-3100.
-
(2011)
Gastroenterol.
, vol.17
, pp. 3092-3100
-
-
Rizzo, A.1
Pallone, F.2
Monteleone, G.3
Fantini, M.C.4
-
10
-
-
77955279767
-
Mechanisms by which inflammation may increase intestinal cancer risk in inflammatory bowel disease
-
O'Connor, P.M., Lapointe, T.K., Beck, P.L. and Buret, A.G. (2010) Mechanisms by which inflammation may increase intestinal cancer risk in inflammatory bowel disease. Inflamm. Bowel Dis., 16, 1411-1420.
-
(2010)
Inflamm. Bowel Dis.
, vol.16
, pp. 1411-1420
-
-
O'Connor, P.M.1
Lapointe, T.K.2
Beck, P.L.3
Buret, A.G.4
-
11
-
-
40049091475
-
Cancer in inflammatory bowel disease
-
Xie, J. and Itzkowitz, S.H. (2008) Cancer in inflammatory bowel disease. World J. Gastroenterol., 14, 378-389.
-
(2008)
World J. Gastroenterol.
, vol.14
, pp. 378-389
-
-
Xie, J.1
Itzkowitz, S.H.2
-
12
-
-
67349129707
-
Familial aggregation in Crohn's disease and ulcerative colitis in a Norwegian population-based cohort followed for ten years
-
Bengtson, M.B., Solberg, C., Aamodt, G., Sauar, J., Jahnsen, J., Moum, B., Lygren, I. and Vatn, M.H. (2009) Familial aggregation in Crohn's disease and ulcerative colitis in a Norwegian population-based cohort followed for ten years. J. Crohn's Colitis, 3, 92-99.
-
(2009)
J. Crohn's Colitis
, vol.3
, pp. 92-99
-
-
Bengtson, M.B.1
Solberg, C.2
Aamodt, G.3
Sauar, J.4
Jahnsen, J.5
Moum, B.6
Lygren, I.7
Vatn, M.H.8
-
13
-
-
84959893914
-
Implications of polygenic risk for personalised colorectal cancer screening
-
Frampton, M.J., Law, P., Litchfield, K., Morris, E.J., Kerr, D., Turnbull, C., Tomlinson, I.P. and Houlston, R.S. (2015) Implications of polygenic risk for personalised colorectal cancer screening. Ann. Oncol., 27, 429-434.
-
(2015)
Ann. Oncol.
, vol.27
, pp. 429-434
-
-
Frampton, M.J.1
Law, P.2
Litchfield, K.3
Morris, E.J.4
Kerr, D.5
Turnbull, C.6
Tomlinson, I.P.7
Houlston, R.S.8
-
14
-
-
84930225190
-
A new GWAS and metaanalysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer
-
Al-Tassan, N.A., Whiffin, N., Hosking, F.J., Palles, C., Farrington, S.M., Dobbins, S.E., Harris, R., Gorman, M., Tenesa, A., Meyer, B.F. et al. (2015) A new GWAS and metaanalysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer. Sci. Rep., 5, 10442.
-
(2015)
Sci. Rep.
, vol.5
, pp. 10442
-
-
Al-Tassan, N.A.1
Whiffin, N.2
Hosking, F.J.3
Palles, C.4
Farrington, S.M.5
Dobbins, S.E.6
Harris, R.7
Gorman, M.8
Tenesa, A.9
Meyer, B.F.10
-
15
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
Jostins, L., Ripke, S., Weersma, R.K., Duerr, R.H., McGovern, D.P., Hui, K.Y., Lee, J.C., Schumm, L.P., Sharma, Y., Anderson, C.A. et al. (2012) Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature, 491, 119-124.
-
(2012)
Nature
, vol.491
, pp. 119-124
-
-
Jostins, L.1
Ripke, S.2
Weersma, R.K.3
Duerr, R.H.4
McGovern, D.P.5
Hui, K.Y.6
Lee, J.C.7
Schumm, L.P.8
Sharma, Y.9
Anderson, C.A.10
-
16
-
-
84940771118
-
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
-
Liu, J.Z., van Sommeren, S., Huang, H., Ng, S.C., Alberts, R., Takahashi, A., Ripke, S., Lee, J.C., Jostins, L., Shah, T. et al. (2015) Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. Nat. Genet., 47, 979-986.
-
(2015)
Nat. Genet.
, vol.47
, pp. 979-986
-
-
Liu, J.Z.1
van Sommeren, S.2
Huang, H.3
Ng, S.C.4
Alberts, R.5
Takahashi, A.6
Ripke, S.7
Lee, J.C.8
Jostins, L.9
Shah, T.10
-
17
-
-
40649127731
-
Wnt4 inhibits beta-catenin/TCF signalling by redirecting beta-catenin to the cell membrane
-
Bernard, P., Fleming, A., Lacombe, A., Harley, V.R. and Vilain, E. (2008) Wnt4 inhibits beta-catenin/TCF signalling by redirecting beta-catenin to the cell membrane. Biol. Cell, 100, 167-177.
-
(2008)
Biol. Cell
, vol.100
, pp. 167-177
-
-
Bernard, P.1
Fleming, A.2
Lacombe, A.3
Harley, V.R.4
Vilain, E.5
-
18
-
-
79951472912
-
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis
-
Kress, T.R., Cannell, I.G., Brenkman, A.B., Samans, B., Gaestel, M., Roepman, P., Burgering, B.M., Bushell, M., Rosenwald, A. and Eilers, M. (2011) The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis. Mol. Cell, 41, 445-457.
-
(2011)
Mol. Cell
, vol.41
, pp. 445-457
-
-
Kress, T.R.1
Cannell, I.G.2
Brenkman, A.B.3
Samans, B.4
Gaestel, M.5
Roepman, P.6
Burgering, B.M.7
Bushell, M.8
Rosenwald, A.9
Eilers, M.10
-
19
-
-
84916226950
-
MicroRNA-96 promotes the proliferation of colorectal cancer cells and targets tumor protein p53 inducible nuclear protein 1, forkhead box protein O1 (FOXO1) and FOXO3a
-
Gao, F. and Wang, W. (2015) MicroRNA-96 promotes the proliferation of colorectal cancer cells and targets tumor protein p53 inducible nuclear protein 1, forkhead box protein O1 (FOXO1) and FOXO3a. Mol. Med. Rep., 11, 1200-1206.
-
(2015)
Mol. Med. Rep.
, vol.11
, pp. 1200-1206
-
-
Gao, F.1
Wang, W.2
-
20
-
-
79958772180
-
Cdc42 in oncogenic transformation, invasion, and tumorigenesis
-
Stengel, K. and Zheng, Y. (2011) Cdc42 in oncogenic transformation, invasion, and tumorigenesis. Cell. Signal., 23, 1415-1423.
-
(2011)
Cell. Signal.
, vol.23
, pp. 1415-1423
-
-
Stengel, K.1
Zheng, Y.2
-
21
-
-
34547643060
-
Phosphoprotein Keratin 23 accumulates in MSS but not MSI colon cancers in vivo and impacts viability and proliferation in vitro
-
Birkenkamp-Demtroder, K., Mansilla, F., Sorensen, F.B., Kruhoffer, M., Cabezon, T., Christensen, L.L., Aaltonen, L.A., Verspaget, H.W. and Orntoft, T.F. (2007) Phosphoprotein Keratin 23 accumulates in MSS but not MSI colon cancers in vivo and impacts viability and proliferation in vitro. Mol. Oncol., 1, 181-195.
-
(2007)
Mol. Oncol.
, vol.1
, pp. 181-195
-
-
Birkenkamp-Demtroder, K.1
Mansilla, F.2
Sorensen, F.B.3
Kruhoffer, M.4
Cabezon, T.5
Christensen, L.L.6
Aaltonen, L.A.7
Verspaget, H.W.8
Orntoft, T.F.9
-
22
-
-
84962448950
-
LENS: Web-based lens for enrichment and network studies of human proteins
-
Handen, A. and Ganapathiraju, M.K. (2015) LENS: web-based lens for enrichment and network studies of human proteins. BMC Med. Genom., 8(Suppl 4), S2.
-
(2015)
BMC Med. Genom
, vol.8
, pp. S2
-
-
Handen, A.1
Ganapathiraju, M.K.2
-
23
-
-
79957489941
-
Mutations in PNKD causing paroxysmal dyskinesia alters protein cleavage and stability
-
Shen, Y., Lee, H.Y., Rawson, J., Ojha, S., Babbitt, P., Fu, Y.H. and Ptacek, L.J. (2011) Mutations in PNKD causing paroxysmal dyskinesia alters protein cleavage and stability. Hum. Mol. Genet., 20, 2322-2332.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2322-2332
-
-
Shen, Y.1
Lee, H.Y.2
Rawson, J.3
Ojha, S.4
Babbitt, P.5
Fu, Y.H.6
Ptacek, L.J.7
-
24
-
-
78049370987
-
Oxidative stress, inflammation, and cancer: How are they linked? Free Radic
-
Reuter, S., Gupta, S.C., Chaturvedi, M.M. and Aggarwal, B.B. (2010) Oxidative stress, inflammation, and cancer: how are they linked? Free Radic. Biol. Med., 49, 1603-1616.
-
(2010)
Biol. Med.
, vol.49
, pp. 1603-1616
-
-
Reuter, S.1
Gupta, S.C.2
Chaturvedi, M.M.3
Aggarwal, B.B.4
-
25
-
-
84894263970
-
TMBIM protein family: Ancestral regulators of cell death
-
Rojas-Rivera, D. and Hetz, C. (2015) TMBIM protein family: ancestral regulators of cell death. Oncogene, 34, 269-280.
-
(2015)
Oncogene
, vol.34
, pp. 269-280
-
-
Rojas-Rivera, D.1
Hetz, C.2
-
26
-
-
79951579431
-
A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface
-
Shukla, S., Fujita, K., Xiao, Q., Liao, Z., Garfield, S. and Srinivasula, S.M. (2011) A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface. Apoptosis, 16, 162-173.
-
(2011)
Apoptosis
, vol.16
, pp. 162-173
-
-
Shukla, S.1
Fujita, K.2
Xiao, Q.3
Liao, Z.4
Garfield, S.5
Srinivasula, S.M.6
-
27
-
-
0035102552
-
Immune privilege or inflammation? Insights into the Fas ligand enigma
-
O'Connell, J., Houston, A., Bennett, M.W., O'Sullivan, G.C. and Shanahan, F. (2001) Immune privilege or inflammation? Insights into the Fas ligand enigma. Nat. Med., 7, 271-274.
-
(2001)
Nat. Med.
, vol.7
, pp. 271-274
-
-
O'Connell, J.1
Houston, A.2
Bennett, M.W.3
O'Sullivan, G.C.4
Shanahan, F.5
-
28
-
-
84940654101
-
Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer
-
Khalili, H., Gong, J., Brenner, H., Austin, T.R., Hutter, C.M., Baba, Y., Baron, J.A., Berndt, S.I., Bezieau, S., Caan, B. et al. (2015) Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer. Carcinogenesis, 36, 999-1007.
-
(2015)
Carcinogenesis
, vol.36
, pp. 999-1007
-
-
Khalili, H.1
Gong, J.2
Brenner, H.3
Austin, T.R.4
Hutter, C.M.5
Baba, Y.6
Baron, J.A.7
Berndt, S.I.8
Bezieau, S.9
Caan, B.10
-
29
-
-
84963955533
-
Inflammatory and redox reactions in colorectal carcinogenesis
-
Guina, T., Biasi, F., Calfapietra, S., Nano, M. and Poli, G. (2015) Inflammatory and redox reactions in colorectal carcinogenesis. Ann. N. Y. Acad. Sci., 1340, 95-103.
-
(2015)
Ann. N. Y. Acad. Sci.
, vol.1340
, pp. 95-103
-
-
Guina, T.1
Biasi, F.2
Calfapietra, S.3
Nano, M.4
Poli, G.5
-
30
-
-
77955398591
-
Fucosyltransferase 2 (FUT2) nonsecretor status is associated with Crohn's disease
-
McGovern, D.P., Jones, M.R., Taylor, K.D., Marciante, K., Yan, X., Dubinsky, M., Ippoliti, A., Vasiliauskas, E., Berel, D., Derkowski, C. et al. (2010) Fucosyltransferase 2 (FUT2) nonsecretor status is associated with Crohn's disease. Hum. Mol. Genet., 19, 3468-3476.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3468-3476
-
-
McGovern, D.P.1
Jones, M.R.2
Taylor, K.D.3
Marciante, K.4
Yan, X.5
Dubinsky, M.6
Ippoliti, A.7
Vasiliauskas, E.8
Berel, D.9
Derkowski, C.10
-
31
-
-
84896461847
-
Interactions between the dietary polyunsaturated fatty acid ratio and genetic factors determine susceptibility to pediatric Crohn's disease
-
Costea, I., Mack, D.R., Lemaitre, R.N., Israel, D., Marcil, V., Ahmad, A. and Amre, D.K. (2014) Interactions between the dietary polyunsaturated fatty acid ratio and genetic factors determine susceptibility to pediatric Crohn's disease. Gastroenterology, 146, 929-931.
-
(2014)
Gastroenterology
, vol.146
, pp. 929-931
-
-
Costea, I.1
Mack, D.R.2
Lemaitre, R.N.3
Israel, D.4
Marcil, V.5
Ahmad, A.6
Amre, D.K.7
-
32
-
-
83755219473
-
Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
-
Molodecky, N.A., Soon, I.S., Rabi, D.M., Ghali, W.A., Ferris, M., Chernoff, G., Benchimol, E.I., Panaccione, R., Ghosh, S., Barkema, H.W. et al. (2012) Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology, 142, 46-54. e42.
-
(2012)
Gastroenterology
, vol.142
-
-
Molodecky, N.A.1
Soon, I.S.2
Rabi, D.M.3
Ghali, W.A.4
Ferris, M.5
Chernoff, G.6
Benchimol, E.I.7
Panaccione, R.8
Ghosh, S.9
Barkema, H.W.10
-
33
-
-
0032555020
-
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease
-
Aaltonen, L.A., Salovaara, R., Kristo, P., Canzian, F., Hemminki, A., Peltomaki, P., Chadwick, R.B., Kaariainen, H., Eskelinen, M., Jarvinen, H. et al. (1998) Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N. Engl. J. Med., 338, 1481-1487.
-
(1998)
N. Engl. J. Med.
, vol.338
, pp. 1481-1487
-
-
Aaltonen, L.A.1
Salovaara, R.2
Kristo, P.3
Canzian, F.4
Hemminki, A.5
Peltomaki, P.6
Chadwick, R.B.7
Kaariainen, H.8
Eskelinen, M.9
Jarvinen, H.10
-
34
-
-
84867594453
-
Cohort profile: The corogene study
-
Vaara, S., Nieminen, M.S., Lokki, M.L., Perola, M., Pussinen, P.J., Allonen, J., Parkkonen, O. and Sinisalo, J. (2012) Cohort profile: the corogene study. Int. J. Epidemiol., 41, 1265-1271.
-
(2012)
Int. J. Epidemiol.
, vol.41
, pp. 1265-1271
-
-
Vaara, S.1
Nieminen, M.S.2
Lokki, M.L.3
Perola, M.4
Pussinen, P.J.5
Allonen, J.6
Parkkonen, O.7
Sinisalo, J.8
-
35
-
-
84860814711
-
Genome-wide screen for metabolic syndrome susceptibility loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits
-
Kristiansson, K., Perola, M., Tikkanen, E., Kettunen, J., Surakka, I., Havulinna, A.S., Stancakova, A., Barnes, C., Widen, E., Kajantie, E. et al. (2012) Genome-wide screen for metabolic syndrome susceptibility loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. Circ. Cardiovasc. Genet., 5, 242-249.
-
(2012)
Circ. Cardiovasc. Genet.
, vol.5
, pp. 242-249
-
-
Kristiansson, K.1
Perola, M.2
Tikkanen, E.3
Kettunen, J.4
Surakka, I.5
Havulinna, A.S.6
Stancakova, A.7
Barnes, C.8
Widen, E.9
Kajantie, E.10
-
36
-
-
84857648463
-
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
-
Kettunen, J., Tukiainen, T., Sarin, A.P., Ortega-Alonso, A., Tikkanen, E., Lyytikainen, L.P., Kangas, A.J., Soininen, P., Wurtz, P., Silander, K. et al. (2012) Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nat. Genet., 44, 269-276.
-
(2012)
Nat. Genet.
, vol.44
, pp. 269-276
-
-
Kettunen, J.1
Tukiainen, T.2
Sarin, A.P.3
Ortega-Alonso, A.4
Tikkanen, E.5
Lyytikainen, L.P.6
Kangas, A.J.7
Soininen, P.8
Wurtz, P.9
Silander, K.10
-
37
-
-
82355190923
-
Early growth and coronary heart disease and type 2 diabetes: Findings from the Helsinki Birth Cohort Study (HBCS)
-
Eriksson, J.G. (2011) Early growth and coronary heart disease and type 2 diabetes: findings from the Helsinki Birth Cohort Study (HBCS). Am. J. Clin. Nutr., 94, 1799S-1802S.
-
(2011)
Am. J. Clin. Nutr.
, vol.94
, pp. 1799S-1802S
-
-
Eriksson, J.G.1
-
38
-
-
78049523725
-
Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: Final results of the VICTOR trial
-
Midgley, R.S., McConkey, C.C., Johnstone, E.C., Dunn, J.A., Smith, J.L., Grumett, S.A., Julier, P., Iveson, C., Yanagisawa, Y., Warren, B. et al. (2010) Phase III randomized trial assessing rofecoxib in the adjuvant setting of colorectal cancer: final results of the VICTOR trial. J. Clin. Oncol., 28, 4575-4580.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 4575-4580
-
-
Midgley, R.S.1
McConkey, C.C.2
Johnstone, E.C.3
Dunn, J.A.4
Smith, J.L.5
Grumett, S.A.6
Julier, P.7
Iveson, C.8
Yanagisawa, Y.9
Warren, B.10
-
39
-
-
32144461525
-
Cohort profile: 1958 British birth cohort (National Child Development Study)
-
Power, C. and Elliott, J. (2006) Cohort profile: 1958 British birth cohort (National Child Development Study). Int. J. Epidemiol., 35, 34-41.
-
(2006)
Int. J. Epidemiol.
, vol.35
, pp. 34-41
-
-
Power, C.1
Elliott, J.2
-
40
-
-
38849170356
-
Colon Cancer Family Registry: An international resource for studies of the genetic epidemiology of colon cancer
-
Newcomb, P.A., Baron, J., Cotterchio, M., Gallinger, S., Grove, J., Haile, R., Hall, D., Hopper, J.L., Jass, J., Le Marchand, L. et al. (2007) Colon Cancer Family Registry: an international resource for studies of the genetic epidemiology of colon cancer. Cancer Epidemiol. Biomark. Prev., 16, 2331-2343.
-
(2007)
Cancer Epidemiol. Biomark. Prev.
, vol.16
, pp. 2331-2343
-
-
Newcomb, P.A.1
Baron, J.2
Cotterchio, M.3
Gallinger, S.4
Grove, J.5
Haile, R.6
Hall, D.7
Hopper, J.L.8
Jass, J.9
Le Marchand, L.10
-
41
-
-
34250001297
-
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
-
Hunter, D.J., Kraft, P., Jacobs, K.B., Cox, D.G., Yeager, M., Hankinson, S.E., Wacholder, S., Wang, Z., Welch, R., Hutchinson, A. et al. (2007) A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat. Genet., 39, 870-874.
-
(2007)
Nat. Genet.
, vol.39
, pp. 870-874
-
-
Hunter, D.J.1
Kraft, P.2
Jacobs, K.B.3
Cox, D.G.4
Yeager, M.5
Hankinson, S.E.6
Wacholder, S.7
Wang, Z.8
Welch, R.9
Hutchinson, A.10
-
42
-
-
34247548755
-
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
-
Yeager, M., Orr, N., Hayes, R.B., Jacobs, K.B., Kraft, P., Wacholder, S., Minichiello, M.J., Fearnhead, P., Yu, K., Chatterjee, N. et al. (2007) Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat. Genet., 39, 645-649.
-
(2007)
Nat. Genet.
, vol.39
, pp. 645-649
-
-
Yeager, M.1
Orr, N.2
Hayes, R.B.3
Jacobs, K.B.4
Kraft, P.5
Wacholder, S.6
Minichiello, M.J.7
Fearnhead, P.8
Yu, K.9
Chatterjee, N.10
-
43
-
-
79959337678
-
Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: Results of the randomised phase 3 MRC COIN trial
-
Maughan, T.S., Adams, R.A., Smith, C.G., Meade, A.M., Seymour, M.T., Wilson, R.H., Idziaszczyk, S., Harris, R., Fisher, D., Kenny, S.L. et al. (2011) Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial. Lancet, 377, 2103-2114.
-
(2011)
Lancet
, vol.377
, pp. 2103-2114
-
-
Maughan, T.S.1
Adams, R.A.2
Smith, C.G.3
Meade, A.M.4
Seymour, M.T.5
Wilson, R.H.6
Idziaszczyk, S.7
Harris, R.8
Fisher, D.9
Kenny, S.L.10
-
44
-
-
27644546712
-
Population structure, differential bias and genomic control in a large-scale, case-control association study
-
Clayton, D.G., Walker, N.M., Smyth, D.J., Pask, R., Cooper, J.D., Maier, L.M., Smink, L.J., Lam, A.C., Ovington, N.R., Stevens, H.E. et al. (2005) Population structure, differential bias and genomic control in a large-scale, case-control association study. Nat. Genet., 37, 1243-1246.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1243-1246
-
-
Clayton, D.G.1
Walker, N.M.2
Smyth, D.J.3
Pask, R.4
Cooper, J.D.5
Maier, L.M.6
Smink, L.J.7
Lam, A.C.8
Ovington, N.R.9
Stevens, H.E.10
-
45
-
-
35648977025
-
National study of colorectal cancer genetics
-
Penegar, S., Wood, W., Lubbe, S., Chandler, I., Broderick, P., Papaemmanuil, E., Sellick, G., Gray, R., Peto, J. and Houlston, R. (2007) National study of colorectal cancer genetics. Br. J. Cancer, 97, 1305-1309.
-
(2007)
Br. J. Cancer
, vol.97
, pp. 1305-1309
-
-
Penegar, S.1
Wood, W.2
Lubbe, S.3
Chandler, I.4
Broderick, P.5
Papaemmanuil, E.6
Sellick, G.7
Gray, R.8
Peto, J.9
Houlston, R.10
-
46
-
-
52049111037
-
Identification of low penetrance alleles for lung cancer: The GEnetic Lung CAncer Predisposition Study (GELCAPS)
-
Eisen, T., Matakidou, A., Houlston, R. and Consortium, G. (2008) Identification of low penetrance alleles for lung cancer: the GEnetic Lung CAncer Predisposition Study (GELCAPS). BMC Cancer, 8, 244.
-
(2008)
BMC Cancer
, vol.8
, pp. 244
-
-
Eisen, T.1
Matakidou, A.2
Houlston, R.3
Consortium, G.4
-
47
-
-
79961135005
-
-
Vienna, Austria. R Foundation for Statistical Computing
-
R Development Core Team. (2011). R: a Language and Environment for Statistical Computing. Vienna, Austria. R Foundation for Statistical Computing. ISBN: 3-900051-07-0.
-
(2011)
R: A Language and Environment for Statistical Computing
-
-
-
48
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M.A., Bender, D., Maller, J., Sklar, P., de Bakker, P.I., Daly, M.J. et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet., 81, 559-575.
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
Maller, J.7
Sklar, P.8
de Bakker, P.I.9
Daly, M.J.10
-
49
-
-
84856478855
-
A linear complexity phasing method for thousands of genomes
-
Delaneau, O., Marchini, J. and Zagury, J.F. (2012) A linear complexity phasing method for thousands of genomes. Nat. Methods, 9, 179-181.
-
(2012)
Nat. Methods
, vol.9
, pp. 179-181
-
-
Delaneau, O.1
Marchini, J.2
Zagury, J.F.3
-
50
-
-
67651222400
-
A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
-
Howie, B.N., Donnelly, P. and Marchini, J. (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet., 5, e1000529.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000529
-
-
Howie, B.N.1
Donnelly, P.2
Marchini, J.3
-
51
-
-
84975795680
-
The 1000 Genomes Project Consortium(2012) An integrated map of genetic variation from 1,092 human genomes
-
The 1000 Genomes Project Consortium(2012) An integrated map of genetic variation from 1,092 human genomes. Nature, 491, 56-65.
-
Nature
, vol.491
, pp. 56-65
-
-
-
52
-
-
34347344976
-
A new multipoint method for genome-wide association studies by imputation of genotypes
-
Marchini, J., Howie, B., Myers, S., McVean, G. and Donnelly, P. (2007) A new multipoint method for genome-wide association studies by imputation of genotypes. Nat. Genet., 39, 906-913.
-
(2007)
Nat. Genet.
, vol.39
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
-
53
-
-
77951751034
-
Meta-analysis and imputation refines the association of 15q25 with smoking quantity
-
Liu, J.Z., Tozzi, F., Waterworth, D.M., Pillai, S.G., Muglia, P., Middleton, L., Berrettini, W., Knouff, C.W., Yuan, X., Waeber, G. et al. (2010) Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat. Genet., 42, 436-440.
-
(2010)
Nat. Genet.
, vol.42
, pp. 436-440
-
-
Liu, J.Z.1
Tozzi, F.2
Waterworth, D.M.3
Pillai, S.G.4
Muglia, P.5
Middleton, L.6
Berrettini, W.7
Knouff, C.W.8
Yuan, X.9
Waeber, G.10
-
54
-
-
0037098199
-
Quantifying heterogeneity in a meta-analysis
-
Higgins, J.P. and Thompson, S.G. (2002) Quantifying heterogeneity in a meta-analysis. Stat. Med., 21, 1539-1558.
-
(2002)
Stat. Med.
, vol.21
, pp. 1539-1558
-
-
Higgins, J.P.1
Thompson, S.G.2
-
55
-
-
0032534069
-
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
-
Boland, C.R., Thibodeau, S.N., Hamilton, S.R., Sidransky, D., Eshleman, J.R., Burt, R.W., Meltzer, S.J., Rodriguez-Bigas, M.A., Fodde, R., Ranzani, G.N. et al. (1998) A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res., 58, 5248-5257.
-
(1998)
Cancer Res.
, vol.58
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
Sidransky, D.4
Eshleman, J.R.5
Burt, R.W.6
Meltzer, S.J.7
Rodriguez-Bigas, M.A.8
Fodde, R.9
Ranzani, G.N.10
-
56
-
-
84881255039
-
Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy +/-cetuximab
-
Smith, C.G., Fisher, D., Claes, B., Maughan, T.S., Idziaszczyk, S., Peuteman, G., Harris, R., James, M.D., Meade, A., Jasani, B. et al. (2013) Somatic profiling of the epidermal growth factor receptor pathway in tumors from patients with advanced colorectal cancer treated with chemotherapy +/-cetuximab. Clin. Cancer Res., 19, 4104-4113.
-
(2013)
Clin. Cancer Res.
, vol.19
, pp. 4104-4113
-
-
Smith, C.G.1
Fisher, D.2
Claes, B.3
Maughan, T.S.4
Idziaszczyk, S.5
Peuteman, G.6
Harris, R.7
James, M.D.8
Meade, A.9
Jasani, B.10
-
57
-
-
84865712382
-
Annotation of functional variation in personal genomes using RegulomeDB
-
Boyle, A.P., Hong, E.L., Hariharan, M., Cheng, Y., Schaub, M.A., Kasowski, M., Karczewski, K.J., Park, J., Hitz, B.C., Weng, S. et al. (2012) Annotation of functional variation in personal genomes using RegulomeDB. Genome Res., 22, 1790-1797.
-
(2012)
Genome Res.
, vol.22
, pp. 1790-1797
-
-
Boyle, A.P.1
Hong, E.L.2
Hariharan, M.3
Cheng, Y.4
Schaub, M.A.5
Kasowski, M.6
Karczewski, K.J.7
Park, J.8
Hitz, B.C.9
Weng, S.10
-
58
-
-
84858779229
-
HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
-
Ward, L.D. and Kellis, M. (2012) HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res., 40, D930-D934.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. D930-D934
-
-
Ward, L.D.1
Kellis, M.2
-
59
-
-
84882738244
-
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites
-
Yan, J., Enge, M., Whitington, T., Dave, K., Liu, J., Sur, I., Schmierer, B., Jolma, A., Kivioja, T., Taipale, M. et al. (2013) Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. Cell, 154, 801-813.
-
(2013)
Cell
, vol.154
, pp. 801-813
-
-
Yan, J.1
Enge, M.2
Whitington, T.3
Dave, K.4
Liu, J.5
Sur, I.6
Schmierer, B.7
Jolma, A.8
Kivioja, T.9
Taipale, M.10
-
60
-
-
84923378921
-
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci
-
Jager, R., Migliorini, G., Henrion, M., Kandaswamy, R., Speedy, H.E., Heindl, A., Whiffin, N., Carnicer, M.J., Broome, L., Dryden, N. et al. (2015) Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci. Nat. Commun., 6, 6178.
-
(2015)
Nat. Commun.
, vol.6
, pp. 6178
-
-
Jager, R.1
Migliorini, G.2
Henrion, M.3
Kandaswamy, R.4
Speedy, H.E.5
Heindl, A.6
Whiffin, N.7
Carnicer, M.J.8
Broome, L.9
Dryden, N.10
-
61
-
-
84857707318
-
ChromHMM: Automating chromatin-state discovery and characterization
-
Ernst, J. and Kellis, M. (2012) ChromHMM: automating chromatin-state discovery and characterization. Nat. Methods, 9, 215-216.
-
(2012)
Nat. Methods
, vol.9
, pp. 215-216
-
-
Ernst, J.1
Kellis, M.2
-
62
-
-
70350236484
-
Biased gene conversion and the evolution of mammalian genomic landscapes
-
Duret, L. and Galtier, N. (2009) Biased gene conversion and the evolution of mammalian genomic landscapes. Ann. Rev. Genom. Hum. Genet., 10, 285-311.
-
(2009)
Ann. Rev. Genom. Hum. Genet.
, vol.10
, pp. 285-311
-
-
Duret, L.1
Galtier, N.2
-
63
-
-
78651237647
-
Identifying a high fraction of the human genome to be under selective constraint using GERP
-
Davydov, E.V., Goode, D.L., Sirota, M., Cooper, G.M., Sidow, A. and Batzoglou, S. (2010) Identifying a high fraction of the human genome to be under selective constraint using GERP. PLoS Comput. Biol., 6, e1001025.
-
(2010)
PLoS Comput. Biol.
, vol.6
, pp. e1001025
-
-
Davydov, E.V.1
Goode, D.L.2
Sirota, M.3
Cooper, G.M.4
Sidow, A.5
Batzoglou, S.6
-
64
-
-
84923324232
-
visPIG-a web tool for producing multiregion, multi-track, multi-scale plots of genetic data
-
Scales, M., Jager, R., Migliorini, G., Houlston, R.S. and Henrion, M.Y. (2014) visPIG-a web tool for producing multiregion, multi-track, multi-scale plots of genetic data. PLoS One, 9, e107497.
-
(2014)
PLoS One
, vol.9
, pp. e107497
-
-
Scales, M.1
Jager, R.2
Migliorini, G.3
Houlston, R.S.4
Henrion, M.Y.5
-
65
-
-
84884994218
-
The Cancer Genome Atlas Pan-Cancer analysis project
-
The Cancer Genome Atlas Research, N., Weinstein, J.N., Collisson, E. A, Mills, G.B., Shaw, K.R.M., Ozenberger, B.A., Ellrott, K., Shmulevich, I., Sander, C. and Stuart, J.M. (2013) The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet, 45, 1113-1120.
-
(2013)
Nat Genet
, vol.45
, pp. 1113-1120
-
-
Weinstein, J.N.1
Collisson, E.A.2
Mills, G.B.3
Shaw, K.R.M.4
Ozenberger, B.A.5
Ellrott, K.6
Shmulevich, I.7
Sander, C.8
Stuart, J.M.9
-
66
-
-
84890172667
-
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
-
Grundberg, E., Meduri, E., Sandling, J.K., Hedman, A.K., Keildson, S., Buil, A., Busche, S., Yuan, W., Nisbet, J., Sekowska, M. et al. (2013) Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements. Am. J. Hum. Genet., 93, 876-890.
-
(2013)
Am. J. Hum. Genet.
, vol.93
, pp. 876-890
-
-
Grundberg, E.1
Meduri, E.2
Sandling, J.K.3
Hedman, A.K.4
Keildson, S.5
Buil, A.6
Busche, S.7
Yuan, W.8
Nisbet, J.9
Sekowska, M.10
-
67
-
-
84885018609
-
Systematic identification of trans eQTLs as putative drivers of known disease associations
-
Westra, H.J., Peters, M.J., Esko, T., Yaghootkar, H., Schurmann, C., Kettunen, J., Christiansen, M.W., Fairfax, B.P., Schramm, K., Powell, J.E. et al. (2013) Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat. Genet., 45, 1238-1243.
-
(2013)
Nat. Genet.
, vol.45
, pp. 1238-1243
-
-
Westra, H.J.1
Peters, M.J.2
Esko, T.3
Yaghootkar, H.4
Schurmann, C.5
Kettunen, J.6
Christiansen, M.W.7
Fairfax, B.P.8
Schramm, K.9
Powell, J.E.10
-
68
-
-
84929001104
-
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
-
The GTEx Consortium(2015) The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. Science, 348, 648-660.
-
(2015)
Science
, vol.348
, pp. 648-660
-
-
-
69
-
-
84885645853
-
Transcriptome and genome sequencing uncovers functional variation in humans
-
Lappalainen, T., Sammeth, M., Friedlander, M.R., 't Hoen, P.A., Monlong, J., Rivas, M.A., Gonzalez-Porta, M., Kurbatova, N., Griebel, T., Ferreira, P.G. et al. (2013) Transcriptome and genome sequencing uncovers functional variation in humans. Nature, 501, 506-511.
-
(2013)
Nature
, vol.501
, pp. 506-511
-
-
Lappalainen, T.1
Sammeth, M.2
Friedlander, M.R.3
't Hoen, P.A.4
Monlong, J.5
Rivas, M.A.6
Gonzalez-Porta, M.7
Kurbatova, N.8
Griebel, T.9
Ferreira, P.G.10
-
70
-
-
84861153094
-
Matrix eQTL: Ultra fast eQTL analysis via large matrix operations
-
Shabalin, A.A. (2012) Matrix eQTL: ultra fast eQTL analysis via large matrix operations. Bioinformatics, 28, 1353-1358.
-
(2012)
Bioinformatics
, vol.28
, pp. 1353-1358
-
-
Shabalin, A.A.1
-
71
-
-
58149193222
-
Human protein reference database-2009 update
-
Keshava Prasad, T.S., Goel, R., Kandasamy, K., Keerthikumar, S., Kumar, S., Mathivanan, S., Telikicherla, D., Raju, R., Shafreen, B., Venugopal, A. et al. (2009) Human protein reference database-2009 update. Nucleic Acids Res., 37, D767-D772.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. D767-D772
-
-
Keshava Prasad, T.S.1
Goel, R.2
Kandasamy, K.3
Keerthikumar, S.4
Kumar, S.5
Mathivanan, S.6
Telikicherla, D.7
Raju, R.8
Shafreen, B.9
Venugopal, A.10
-
72
-
-
84874947727
-
The BioGRID interaction database: 2013 update
-
Chatr-Aryamontri, A., Breitkreutz, B.J., Heinicke, S., Boucher, L., Winter, A., Stark, C., Nixon, J., Ramage, L., Kolas, N., O'Donnell, L. et al. (2013) The BioGRID interaction database: 2013 update. Nucleic Acids Res., 41, D816-D823.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D816-D823
-
-
Chatr-Aryamontri, A.1
Breitkreutz, B.J.2
Heinicke, S.3
Boucher, L.4
Winter, A.5
Stark, C.6
Nixon, J.7
Ramage, L.8
Kolas, N.9
O'Donnell, L.10
-
73
-
-
84891753483
-
The Reactome pathway knowledgebase
-
Croft, D., Mundo, A.F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M.R. et al. (2014) The Reactome pathway knowledgebase. Nucleic Acids Res., 42, D472-D477.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D472-D477
-
-
Croft, D.1
Mundo, A.F.2
Haw, R.3
Milacic, M.4
Weiser, J.5
Wu, G.6
Caudy, M.7
Garapati, P.8
Gillespie, M.9
Kamdar, M.R.10
-
74
-
-
79551587720
-
Cytoscape 2.8: New features for data integration and network visualization
-
Smoot, M.E., Ono, K., Ruscheinski, J., Wang, P.L. and Ideker, T. (2011) Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics, 27, 431-432.
-
(2011)
Bioinformatics
, vol.27
, pp. 431-432
-
-
Smoot, M.E.1
Ono, K.2
Ruscheinski, J.3
Wang, P.L.4
Ideker, T.5
|