-
1
-
-
84918815964
-
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
-
Ferlay, J., I. Soerjomataram, R. Dikshit, et al. 2014. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer 136: E359-E386.
-
(2014)
Int. J. Cancer
, vol.136
, pp. E359-E386
-
-
Ferlay, J.1
Soerjomataram, I.2
Dikshit, R.3
-
2
-
-
84876395218
-
Evolution of disease phenotype in adult and pediatric onset Crohn's disease in a population-based cohort
-
Lovasz, B.D., L. Lakatos, A. Horvath, et al. 2013. Evolution of disease phenotype in adult and pediatric onset Crohn's disease in a population-based cohort. World J. Gastroenterol. 19: 2217-2226.
-
(2013)
World J. Gastroenterol.
, vol.19
, pp. 2217-2226
-
-
Lovasz, B.D.1
Lakatos, L.2
Horvath, A.3
-
3
-
-
84905833585
-
Colorectal cancer in inflammatory bowel disease: the risk, pathogenesis, prevention and diagnosis
-
Kim, E.R. & D.K. Chang. 2014. Colorectal cancer in inflammatory bowel disease: the risk, pathogenesis, prevention and diagnosis. World J. Gastroenterol. 20: 9872-9881.
-
(2014)
World J. Gastroenterol.
, vol.20
, pp. 9872-9881
-
-
Kim, E.R.1
Chang, D.K.2
-
4
-
-
84882722472
-
Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets
-
Biasi, F., G. Leonarduzzi, P.I. Oteiza & G. Poli. 2013. Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets. Antioxid. Redox Signal. 19: 1711-1747.
-
(2013)
Antioxid. Redox Signal.
, vol.19
, pp. 1711-1747
-
-
Biasi, F.1
Leonarduzzi, G.2
Oteiza, P.I.3
Poli, G.4
-
5
-
-
84878691021
-
Oxidative stress in the pathogenesis of colorectal cancer: cause or consequence?
-
Open access article
-
Perše, M. 2013. Oxidative stress in the pathogenesis of colorectal cancer: cause or consequence? Biomed. Res. Int. 2013: Article ID: 725710, Open access article, doi: 10.1155/2013/725710.
-
(2013)
Biomed. Res. Int.
, vol.2013
-
-
Perše, M.1
-
6
-
-
84885919104
-
Chemistry meets biology in colitis-associated carcinogenesis
-
Mangerich, A., P.C. Dedon, J.G. Fox, et al. Chemistry meets biology in colitis-associated carcinogenesis. Free Radic. Res. 47: 958-986.
-
Free Radic. Res.
, vol.47
, pp. 958-986
-
-
Mangerich, A.1
Dedon, P.C.2
Fox, J.G.3
-
7
-
-
33749319703
-
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
-
Galon, J., A. Costes, F. Sanchez-Cabo, et al. 2006. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313: 1960-1964.
-
(2006)
Science
, vol.313
, pp. 1960-1964
-
-
Galon, J.1
Costes, A.2
Sanchez-Cabo, F.3
-
8
-
-
84872130510
-
Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Gαi2-deficient mouse
-
Götlind, Y.Y., M. Fritsch Fredin, A.K. Kumawat, et al. 2013. Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Gαi2-deficient mouse. Int. Immunol. 25: 35-44.
-
(2013)
Int. Immunol.
, vol.25
, pp. 35-44
-
-
Götlind, Y.Y.1
Fritsch Fredin, M.2
Kumawat, A.K.3
-
9
-
-
84867504992
-
The distribution of macrophages with a m1 or m2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer
-
Edin, S., M.L. Wikberg, A.M. Dahlin, et al. 2012. The distribution of macrophages with a m1 or m2 phenotype in relation to prognosis and the molecular characteristics of colorectal cancer. PLoS One 7: e47045.
-
(2012)
PLoS One
, vol.7
, pp. e47045
-
-
Edin, S.1
Wikberg, M.L.2
Dahlin, A.M.3
-
10
-
-
84875492465
-
Tumor associated macrophages and neutrophils in tumor progression
-
Galdiero, M.R., C. Garlanda, S. Jaillon, et al. 2013. Tumor associated macrophages and neutrophils in tumor progression. J. Cell Physiol. 228: 1404-1412.
-
(2013)
J. Cell Physiol.
, vol.228
, pp. 1404-1412
-
-
Galdiero, M.R.1
Garlanda, C.2
Jaillon, S.3
-
11
-
-
84871330172
-
Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice
-
Shang, K., Y.P. Bai, C. Wang, et al. 2012. Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice. PLoS One 7: e51848.
-
(2012)
PLoS One
, vol.7
, pp. e51848
-
-
Shang, K.1
Bai, Y.P.2
Wang, C.3
-
12
-
-
84881116763
-
A derived neutrophil to lymphocyte ratio predicts clinical outcome in stage II and III colon cancer patients
-
Absenger, G., J. Szkandera, M. Pichler, et al. 2013. A derived neutrophil to lymphocyte ratio predicts clinical outcome in stage II and III colon cancer patients. Br. J. Cancer 109: 395-400.
-
(2013)
Br. J. Cancer
, vol.109
, pp. 395-400
-
-
Absenger, G.1
Szkandera, J.2
Pichler, M.3
-
13
-
-
84874105786
-
Inflammation and colorectal cancer: colitis-associated neoplasia
-
Grivennikov, S.I. 2013. Inflammation and colorectal cancer: colitis-associated neoplasia. Semin. Immunopathol. 35: 229-244.
-
(2013)
Semin. Immunopathol.
, vol.35
, pp. 229-244
-
-
Grivennikov, S.I.1
-
14
-
-
76849095665
-
The role of COX-2 in intestinal inflammation and colorectal cancer
-
Wang, D. & R.N. Dubois. 2010. The role of COX-2 in intestinal inflammation and colorectal cancer. Oncogene 29: 781-788.
-
(2010)
Oncogene
, vol.29
, pp. 781-788
-
-
Wang, D.1
Dubois, R.N.2
-
15
-
-
84945198930
-
The impact of inflammatory lipid mediators on colon cancer-initiating cells
-
[Epub ahead of print].
-
Bellamkonda, K., W. Sime & A. Sjölander. 2014. The impact of inflammatory lipid mediators on colon cancer-initiating cells. Mol. Carcinog. doi: 10.1002/mc.22207. [Epub ahead of print].
-
(2014)
Mol. Carcinog.
-
-
Bellamkonda, K.1
Sime, W.2
Sjölander, A.3
-
16
-
-
85028276122
-
Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth
-
[Epub ahead of print].
-
DeSimone, V., E. Franzè, G. Ronchetti, et al. 2014. Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. Oncogene doi: 10.1038/onc.2014.286. [Epub ahead of print].
-
(2014)
Oncogene
-
-
De Simone, V.1
Franzè, E.2
Ronchetti, G.3
-
17
-
-
78649582941
-
Bacterial induction of proinflammatory cytokines in inflammatory bowel disease
-
Klapproth, J.M. & M. Sasaki. 2010. Bacterial induction of proinflammatory cytokines in inflammatory bowel disease. Inflamm. Bowel Dis. 16: 2173-2179.
-
(2010)
Inflamm. Bowel Dis.
, vol.16
, pp. 2173-2179
-
-
Klapproth, J.M.1
Sasaki, M.2
-
18
-
-
84861440163
-
Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis
-
Lee, Y.S., I. Choi, Y. Ning, et al. 2012. Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis. Br. J. Cancer 106: 1833-1841.
-
(2012)
Br. J. Cancer
, vol.106
, pp. 1833-1841
-
-
Lee, Y.S.1
Choi, I.2
Ning, Y.3
-
19
-
-
84864341712
-
Progressive increase of matrix metalloprotease-9 and interleukin-8 serum levels during carcinogenic process in human colorectal tract
-
Biasi, F., T. Guina, M. Maina, et al. 2012. Progressive increase of matrix metalloprotease-9 and interleukin-8 serum levels during carcinogenic process in human colorectal tract. PLoS One 7: e41839.
-
(2012)
PLoS One
, vol.7
, pp. e41839
-
-
Biasi, F.1
Guina, T.2
Maina, M.3
-
20
-
-
84869758362
-
Interleukin-6-a key regulator of colorectal cancer development
-
Waldner, M.J., S. Foersch & M.F. Neurath. 2012. Interleukin-6-a key regulator of colorectal cancer development. Int. J. Biol. Sci. 8: 1248-1253.
-
(2012)
Int. J. Biol. Sci.
, vol.8
, pp. 1248-1253
-
-
Waldner, M.J.1
Foersch, S.2
Neurath, M.F.3
-
21
-
-
84877330590
-
Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis
-
Yu, L.Z., H.Y. Wang, S.P. Yang, et al. 2013. Expression of interleukin-22/STAT3 signaling pathway in ulcerative colitis and related carcinogenesis. World J. Gastroenterol. 19: 2638-2649.
-
(2013)
World J. Gastroenterol.
, vol.19
, pp. 2638-2649
-
-
Yu, L.Z.1
Wang, H.Y.2
Yang, S.P.3
-
22
-
-
84893656308
-
Significant association between IL23R and IL17F polymorphisms and clinical features of colorectal cancer
-
Omrane, I., O. Baroudi, K. Bougatef, et al. 2014. Significant association between IL23R and IL17F polymorphisms and clinical features of colorectal cancer. Immunol. Lett. 158: 189-194.
-
(2014)
Immunol. Lett.
, vol.158
, pp. 189-194
-
-
Omrane, I.1
Baroudi, O.2
Bougatef, K.3
-
23
-
-
84872510974
-
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer
-
Fleming, N.I., R.N. Jorissen, D. Mouradov, et al. 2013. SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res. 73: 725-735.
-
(2013)
Cancer Res.
, vol.73
, pp. 725-735
-
-
Fleming, N.I.1
Jorissen, R.N.2
Mouradov, D.3
-
24
-
-
84857375987
-
Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon
-
Sipos, F. & O. Galamb. 2012. Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon. World J. Gastroenterol. 18: 601-608.
-
(2012)
World J. Gastroenterol.
, vol.18
, pp. 601-608
-
-
Sipos, F.1
Galamb, O.2
-
25
-
-
67650917886
-
Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues
-
Juhasz, A., Y. Ge, S. Markel, et al. 2009. Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues. Free Rad. Res. 43: 523-532.
-
(2009)
Free Rad. Res.
, vol.43
, pp. 523-532
-
-
Juhasz, A.1
Ge, Y.2
Markel, S.3
-
26
-
-
56349142515
-
Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells
-
Kuwano, Y., K. Tominaga, T. Kawahara, et al. 2008. Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells. Free Radic. Biol. Med. 45: 1642-1652.
-
(2008)
Free Radic. Biol. Med.
, vol.45
, pp. 1642-1652
-
-
Kuwano, Y.1
Tominaga, K.2
Kawahara, T.3
-
27
-
-
0034102229
-
The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats
-
Tardieu, D., J.P. Jaeg, A. Deloly, et al. 2000. The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats. Carcinogenesis 21: 973-976.
-
(2000)
Carcinogenesis
, vol.21
, pp. 973-976
-
-
Tardieu, D.1
Jaeg, J.P.2
Deloly, A.3
-
28
-
-
34249903855
-
Oxidative DNA damage and antioxidant activity in patients with inflammatory bowel disease
-
Dincer, Y., Y. Erzin, S. Himmetoglu, et al. 2007. Oxidative DNA damage and antioxidant activity in patients with inflammatory bowel disease. Dig. Dis. Sci. 52: 1636-1641.
-
(2007)
Dig. Dis. Sci.
, vol.52
, pp. 1636-1641
-
-
Dincer, Y.1
Erzin, Y.2
Himmetoglu, S.3
-
29
-
-
0346606862
-
Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease
-
Hussain, S.P., P. Amstad, K. Raja, et al. 2000. Increased p53 mutation load in noncancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res. 60: 3333-3337.
-
(2000)
Cancer Res
, vol.60
, pp. 3333-3337
-
-
Hussain, S.P.1
Amstad, P.2
Raja, K.3
-
30
-
-
25144507232
-
Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis
-
Nishikawa, M., N. Oshitani, T. Matsumoto, et al. 2005. Accumulation of mitochondrial DNA mutation with colorectal carcinogenesis in ulcerative colitis. Br. J. Cancer 93: 331-337.
-
(2005)
Br. J. Cancer
, vol.93
, pp. 331-337
-
-
Nishikawa, M.1
Oshitani, N.2
Matsumoto, T.3
-
31
-
-
45249124663
-
4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest
-
Poli, G., R.J. Schaur, W.G. Siems & G. Leonarduzzi. 2008. 4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest. Med. Res. Rev. 28: 569-631.
-
(2008)
Med. Res. Rev.
, vol.28
, pp. 569-631
-
-
Poli, G.1
Schaur, R.J.2
Siems, W.G.3
Leonarduzzi, G.4
-
32
-
-
33750912209
-
NADPH oxidases in the gastrointestinal tract: a potential role of Nox1 in innate immune response and carcinogenesis
-
Rokutan, K., T. Kawahara, Y. Kuwano, et al. 2006. NADPH oxidases in the gastrointestinal tract: a potential role of Nox1 in innate immune response and carcinogenesis. Antioxid. Redox Signal. 8: 1573-1582.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1573-1582
-
-
Rokutan, K.1
Kawahara, T.2
Kuwano, Y.3
-
33
-
-
0037154250
-
Reactive oxygen generated by Nox1 triggers the angiogenic switch
-
U.S.A.
-
Arbiser, J.L., J. Petros, R. Klafter, et al. 2002. Reactive oxygen generated by Nox1 triggers the angiogenic switch. Proc. Natl. Acad. Sci. U.S.A. 99: 715-720.
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, pp. 715-720
-
-
Arbiser, J.L.1
Petros, J.2
Klafter, R.3
-
34
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
Karin, M. 2006. Nuclear factor-kappaB in cancer development and progression. Nature 441: 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
35
-
-
84856698334
-
BCL2A1: the underdog in the BCL2 family
-
Vogler, M. 2012. BCL2A1: the underdog in the BCL2 family. Cell Death Differ. 19: 67-74.
-
(2012)
Cell Death Differ
, vol.19
, pp. 67-74
-
-
Vogler, M.1
-
36
-
-
84861344780
-
Nuclear factor-κB predicts outcome in locally advanced rectal cancer patients receiving neoadjuvant radio-chemotherapy
-
Berardi, R., E. Maccaroni, A. Mandolesi, et al. 2012. Nuclear factor-κB predicts outcome in locally advanced rectal cancer patients receiving neoadjuvant radio-chemotherapy. Dig. Liver Dis. 44: 617-622.
-
(2012)
Dig. Liver Dis.
, vol.44
, pp. 617-622
-
-
Berardi, R.1
Maccaroni, E.2
Mandolesi, A.3
-
37
-
-
84885922783
-
Redox signaling mediated by the gut microbiota
-
Neish, A.S. 2013. Redox signaling mediated by the gut microbiota. Free Radic. Res. 47: 950-957.
-
(2013)
Free Radic. Res.
, vol.47
, pp. 950-957
-
-
Neish, A.S.1
-
38
-
-
84872607437
-
JAK/STAT/SOCS-signaling pathway and colon and rectal cancer
-
Slattery, M.L., A. Lundgreen, S.A. Kadlubar, et al. 2013. JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. Mol. Carcinog. 52: 155-166.
-
(2013)
Mol. Carcinog.
, vol.52
, pp. 155-166
-
-
Slattery, M.L.1
Lundgreen, A.2
Kadlubar, S.A.3
-
39
-
-
84907286255
-
Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice
-
He, Z., X. He, Z. Chen, et al. 2014. Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice. Oncol. Rep. 32: 1873-1880.
-
(2014)
Oncol. Rep.
, vol.32
, pp. 1873-1880
-
-
He, Z.1
He, X.2
Chen, Z.3
-
40
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
-
Wu, S., K.J. Rhee, E. Albesiano, et al. 2009. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat. Med. 15: 1016-1022.
-
(2009)
Nat. Med.
, vol.15
, pp. 1016-1022
-
-
Wu, S.1
Rhee, K.J.2
Albesiano, E.3
-
42
-
-
84883736109
-
Oncogenic functions of the transcription factor Nrf2
-
Gañán-Gómez, I., Y. Wei, H. Yang, et al. 2013. Oncogenic functions of the transcription factor Nrf2. Free Radic. Biol. Med. 65: 750-764.
-
(2013)
Free Radic. Biol. Med.
, vol.65
, pp. 750-764
-
-
Gañán-Gómez, I.1
Wei, Y.2
Yang, H.3
-
43
-
-
84889575198
-
Modulation of oxidative stress as an anticancer strategy
-
Gorrini, C., I.S. Harris & T.W. Mak. 2013. Modulation of oxidative stress as an anticancer strategy. Nat. Rev. Drug Discov. 12: 931-947.
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 931-947
-
-
Gorrini, C.1
Harris, I.S.2
Mak, T.W.3
-
44
-
-
77955279350
-
A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders
-
Kim, J., Y.N. Cha & Y.J. Surh. 2010. A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders. Mutat. Res. 690: 12-23.
-
(2010)
Mutat. Res.
, vol.690
, pp. 12-23
-
-
Kim, J.1
Cha, Y.N.2
Surh, Y.J.3
-
45
-
-
84871519753
-
The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance
-
Rushworth, S.A., L. Zaitseva, M.Y. Murray, et al. 2012. The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance. Blood 120: 5188-5198.
-
(2012)
Blood
, vol.120
, pp. 5188-5198
-
-
Rushworth, S.A.1
Zaitseva, L.2
Murray, M.Y.3
-
46
-
-
84902066943
-
Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity
-
Yin, H., J. Fang, L. Liao, et al. 2014. Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity. BMC Cancer 14: 436.
-
(2014)
BMC Cancer
, vol.14
, pp. 436
-
-
Yin, H.1
Fang, J.2
Liao, L.3
-
47
-
-
79952276580
-
Heme oxygenase-1 in tumor biology and therapy
-
Was, H., J. Dulak & A. Jozkowicz. 2010. Heme oxygenase-1 in tumor biology and therapy. Curr. Drug Targets 11: 1551-1570.
-
(2010)
Curr. Drug Targets
, vol.11
, pp. 1551-1570
-
-
Was, H.1
Dulak, J.2
Jozkowicz, A.3
-
48
-
-
84907528560
-
Heme oxygenase-1 has antitumoral effects in colorectal cancer: Involvement of p53
-
Andrés, N.C., M.E. Fermento, N.A. Gandini, et al. 2014. Heme oxygenase-1 has antitumoral effects in colorectal cancer: Involvement of p53. Exp. Mol. Pathol. 97: 321-331.
-
(2014)
Exp. Mol. Pathol.
, vol.97
, pp. 321-331
-
-
Andrés, N.C.1
Fermento, M.E.2
Gandini, N.A.3
-
49
-
-
34250193619
-
Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer
-
Becker, J.C., H. Fukui, Y. Imai, et al. 2007. Colonic expression of heme oxygenase-1 is associated with a better long-term survival in patients with colorectal cancer. Scand. J. Gastroenterol. 42: 852-858.
-
(2007)
Scand. J. Gastroenterol.
, vol.42
, pp. 852-858
-
-
Becker, J.C.1
Fukui, H.2
Imai, Y.3
-
50
-
-
49149126717
-
Analysis of oxidative DNA damage in patients with colorectal cancer
-
Ribeiro, M.L., D.G. Priolli, D.D. Miranda, et al. 2008. Analysis of oxidative DNA damage in patients with colorectal cancer. Clin. Colorectal Cancer 7: 267-272.
-
(2008)
Clin. Colorectal Cancer
, vol.7
, pp. 267-272
-
-
Ribeiro, M.L.1
Priolli, D.G.2
Miranda, D.D.3
|