-
1
-
-
0017130525
-
Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors
-
[PubMed PMID: 820877]
-
[1] Morales, A., Eidinger, D., Bruce, A.W., Intracavitary Bacillus Calmette-Guerin in the treatment of superficial bladder tumors. J Urol 116 (1976), 180–183 [PubMed PMID: 820877].
-
(1976)
J Urol
, vol.116
, pp. 180-183
-
-
Morales, A.1
Eidinger, D.2
Bruce, A.W.3
-
2
-
-
0033973840
-
Efficacy and safety of valrubicin for the treatment of Bacillus Calmette-Guerin refractory carcinoma in situ of the bladder. The Valrubicin Study Group
-
[PubMed PMID: 10687972]
-
[2] Steinberg, G., Bahnson, R., Brosman, S., Middleton, R., Wajsman, Z., Wehle, M., Efficacy and safety of valrubicin for the treatment of Bacillus Calmette-Guerin refractory carcinoma in situ of the bladder. The Valrubicin Study Group. J Urol 163 (2000), 761–767 [PubMed PMID: 10687972].
-
(2000)
J Urol
, vol.163
, pp. 761-767
-
-
Steinberg, G.1
Bahnson, R.2
Brosman, S.3
Middleton, R.4
Wajsman, Z.5
Wehle, M.6
-
3
-
-
84918815964
-
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
-
[PubMed PMID: 25220842]
-
[3] Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 136 (2015), E359–E386, 10.1002/ijc.29210 [PubMed PMID: 25220842].
-
(2015)
Int J Cancer
, vol.136
, pp. E359-E386
-
-
Ferlay, J.1
Soerjomataram, I.2
Dikshit, R.3
Eser, S.4
Mathers, C.5
Rebelo, M.6
-
4
-
-
84897114969
-
The mechanism of action of BCG therapy for bladder cancer—a current perspective
-
[PubMed PMID: 24492433]
-
[4] Redelman-Sidi, G., Glickman, M.S., Bochner, B.H., The mechanism of action of BCG therapy for bladder cancer—a current perspective. Nat Rev Urol 11 (2014), 153–162, 10.1038/nrurol.2014.15 [PubMed PMID: 24492433].
-
(2014)
Nat Rev Urol
, vol.11
, pp. 153-162
-
-
Redelman-Sidi, G.1
Glickman, M.S.2
Bochner, B.H.3
-
5
-
-
84923078390
-
MPDL32.8.0. A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
-
[PubMed PMID: 25428503]
-
[5] Powles, T., Eder, J.P., Fine, G.D., Braiteh, F.S., Loriot, Y., Cruz, C., et al. MPDL32.8.0. A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 515 (2014), 558–562, 10.1038/nature13904 [PubMed PMID: 25428503].
-
(2014)
Nature
, vol.515
, pp. 558-562
-
-
Powles, T.1
Eder, J.P.2
Fine, G.D.3
Braiteh, F.S.4
Loriot, Y.5
Cruz, C.6
-
6
-
-
84929150634
-
Immunologic checkpoints blockade in renal cell, prostate, and urothelial malignancies
-
[PubMed PMID: 25965369]
-
[6] Bracarda, S., Altavilla, A., Hamzaj, A., Sisani, M., Marrocolo, F., Del Buono, S., et al. Immunologic checkpoints blockade in renal cell, prostate, and urothelial malignancies. Semin Oncol 42 (2015), 495–505, 10.1053/j.seminoncol.2015.02.004 [PubMed PMID: 25965369].
-
(2015)
Semin Oncol
, vol.42
, pp. 495-505
-
-
Bracarda, S.1
Altavilla, A.2
Hamzaj, A.3
Sisani, M.4
Marrocolo, F.5
Del Buono, S.6
-
7
-
-
84937516588
-
A systematic review of immunotherapy in urologic cancer: evolving roles for targeting of CTLA-4, PD-1/PD-L1, and HLA-G
-
[PubMed PMID: 2582472]
-
[7] Carosella, E.D., Ploussard, G., LeMaoult, J., Desgrandchamps, F., A systematic review of immunotherapy in urologic cancer: evolving roles for targeting of CTLA-4, PD-1/PD-L1, and HLA-G. Eur Urol 68 (2015), 267–279, 10.1016/j.eururo.2015.02.032 [PubMed PMID: 2582472].
-
(2015)
Eur Urol
, vol.68
, pp. 267-279
-
-
Carosella, E.D.1
Ploussard, G.2
LeMaoult, J.3
Desgrandchamps, F.4
-
8
-
-
84928468444
-
Emerging immunotherapies for bladder cancer
-
[PubMed PMID: 25811346]
-
[8] Kim, J.W., Tomita, Y., Trepel, J., Apolo, A.B., Emerging immunotherapies for bladder cancer. Curr Opin Oncol 27 (2015), 191–200, 10.1097/CCO.0000000000000177 [PubMed PMID: 25811346].
-
(2015)
Curr Opin Oncol
, vol.27
, pp. 191-200
-
-
Kim, J.W.1
Tomita, Y.2
Trepel, J.3
Apolo, A.B.4
-
9
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
[PubMed PMID: 25838375]
-
[9] Schumacher, T.N., Schreiber, R.D., Neoantigens in cancer immunotherapy. Science 348 (2015), 69–74, 10.1126/science.aaa4971 [PubMed PMID: 25838375].
-
(2015)
Science
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
10
-
-
84873111794
-
Type I interferon response and innate immune sensing of cancer
-
[PubMed PMID: 23122052; PMCID: PMC3565059]
-
[10] Fuertes, M.B., Woo, S.R., Burnett, B., Fu, Y.X., Gajewski, T.F., Type I interferon response and innate immune sensing of cancer. Trends Immunol 34 (2013), 67–73, 10.1016/j.it.2012.10.004 [PubMed PMID: 23122052; PMCID: PMC3565059].
-
(2013)
Trends Immunol
, vol.34
, pp. 67-73
-
-
Fuertes, M.B.1
Woo, S.R.2
Burnett, B.3
Fu, Y.X.4
Gajewski, T.F.5
-
11
-
-
80355147292
-
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
-
[PubMed PMID: 21930769; PMCID: PMC3182061]
-
[11] Diamond, M.S., Kinder, M., Matsushita, H., Mashayekhi, M., Dunn, G.P., Archambault, J.M., et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J Exp Med 208 (2011), 1989–2003, 10.1084/jem.20101158 [PubMed PMID: 21930769; PMCID: PMC3182061].
-
(2011)
J Exp Med
, vol.208
, pp. 1989-2003
-
-
Diamond, M.S.1
Kinder, M.2
Matsushita, H.3
Mashayekhi, M.4
Dunn, G.P.5
Archambault, J.M.6
-
12
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
[PubMed PMID: 23945592; PMCID: PMC3776390]
-
[12] Alexandrov, L.B., Nik-Zainal, S., Wedge, D.C., Aparicio, S.A., Behjati, S., Biankin, A.V., et al. Signatures of mutational processes in human cancer. Nature 500 (2013), 415–421, 10.1038/nature12477 [PubMed PMID: 23945592; PMCID: PMC3776390].
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
Biankin, A.V.6
-
13
-
-
84899833582
-
Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden
-
[PubMed PMID: 24777035; PMCID: PMC4010643]
-
[13] Cazier, J.B., Rao, S.R., McLean, C.M., Walker, A.K., Walker, A.L., Wright, B.J., et al. Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden. Nat Commun, 5, 2014, 3756, 10.1038/ncomms4756 [PubMed PMID: 24777035; PMCID: PMC4010643].
-
(2014)
Nat Commun
, vol.5
, pp. 3756
-
-
Cazier, J.B.1
Rao, S.R.2
McLean, C.M.3
Walker, A.K.4
Walker, A.L.5
Wright, B.J.6
-
14
-
-
84897022815
-
Comprehensive molecular characterization of urothelial bladder carcinoma
-
[PubMed PMID: 24476821; PMCID: PMC3962515]
-
[14] Network CGAR, Comprehensive molecular characterization of urothelial bladder carcinoma. Nature 507 (2014), 315–322, 10.1038/nature12965 [PubMed PMID: 24476821; PMCID: PMC3962515].
-
(2014)
Nature
, vol.507
, pp. 315-322
-
-
Network CGAR1
-
15
-
-
0036484220
-
The B7-CD28 superfamily
-
[PubMed PMID: 11910893]
-
[15] Sharpe, A.H., Freeman, G.J., The B7-CD28 superfamily. Nat Rev Immunol 2 (2002), 116–126, 10.1038/nri727 [PubMed PMID: 11910893].
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 116-126
-
-
Sharpe, A.H.1
Freeman, G.J.2
-
16
-
-
0029944533
-
CD28/B7 system of T cell costimulation
-
[PubMed PMID: 8717514]
-
[16] Lenschow, D.J., Walunas, T.L., Bluestone, J.A., CD28/B7 system of T cell costimulation. Annu Rev Immunol 14 (1996), 233–258, 10.1146/annurev.immunol.14.1.233 [PubMed PMID: 8717514].
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 233-258
-
-
Lenschow, D.J.1
Walunas, T.L.2
Bluestone, J.A.3
-
17
-
-
79954459308
-
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family
-
[PubMed PMID: 21488898; PMCID: PMC3077803]
-
[17] Bour-Jordan, H., Esensten, J.H., Martinez-Llordella, M., Penaranda, C., Stumpf, M., Bluestone, J.A., Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family. Immunol Rev 241 (2011), 180–205, 10.1111/j.1600-065X.2011.01011.x [PubMed PMID: 21488898; PMCID: PMC3077803].
-
(2011)
Immunol Rev
, vol.241
, pp. 180-205
-
-
Bour-Jordan, H.1
Esensten, J.H.2
Martinez-Llordella, M.3
Penaranda, C.4
Stumpf, M.5
Bluestone, J.A.6
-
18
-
-
17644389199
-
TNF/TNFR family members in costimulation of T cell responses
-
[PubMed PMID: 15771565]
-
[18] Watts, T.H., TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol 23 (2005), 23–68, 10.1146/annurev.immunol.23.021704.115839 [PubMed PMID: 15771565].
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 23-68
-
-
Watts, T.H.1
-
19
-
-
65349156913
-
Costimulatory and coinhibitory receptors in anti-tumor immunity
-
[PubMed PMID: 19426219; PMCID: PMC3278040]
-
[19] Driessens, G., Kline, J., Gajewski, T.F., Costimulatory and coinhibitory receptors in anti-tumor immunity. Immunol Rev 229 (2009), 126–244, 10.1111/j.1600-065X.2009.00771.x [PubMed PMID: 19426219; PMCID: PMC3278040].
-
(2009)
Immunol Rev
, vol.229
, pp. 126-244
-
-
Driessens, G.1
Kline, J.2
Gajewski, T.F.3
-
20
-
-
0036909587
-
Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses
-
[PubMed PMID: 12516549]
-
[20] Taraban, V.Y., Rowley, T.F., O'Brien, L., Chan, H.T., Haswell, L.E., Green, M.H., et al. Expression and costimulatory effects of the TNF receptor superfamily members CD134 (OX40) and CD137 (4-1BB), and their role in the generation of anti-tumor immune responses. Eur J Immunol 32 (2002), 3617–3627, 10.1002/1521-4141(200212)32:12<3617::AID-IMMU3617>3.0.CO;2-M [PubMed PMID: 12516549].
-
(2002)
Eur J Immunol
, vol.32
, pp. 3617-3627
-
-
Taraban, V.Y.1
Rowley, T.F.2
O'Brien, L.3
Chan, H.T.4
Haswell, L.E.5
Green, M.H.6
-
21
-
-
85029266334
-
LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control
-
[PubMed PMID: PMC4649320]
-
[21] Williams, J.B., Horton, B., Zheng, Y., Gajewski, T.F., LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control. J Immunother Cancer, 3(Suppl 2), 2015, P328-P, 10.1186/2051-1426-3-S2-P328 [PubMed PMID: PMC4649320].
-
(2015)
J Immunother Cancer
, vol.3
, pp. P328-P
-
-
Williams, J.B.1
Horton, B.2
Zheng, Y.3
Gajewski, T.F.4
-
22
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
[PubMed PMID: 22437870]
-
[22] Pardoll, D.M., The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12 (2012), 252–264, 10.1038/nrc3239 [PubMed PMID: 22437870].
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
23
-
-
84942295671
-
T-cell immunoglobulin mucin-3 expression in bladder urothelial carcinoma: clinicopathologic correlations and association with survival
-
[PubMed PMID: 26265374]
-
[23] Yang, M., Yu, Q., Liu, J., Fu, W., Cao, Y., Yu, L., et al. T-cell immunoglobulin mucin-3 expression in bladder urothelial carcinoma: clinicopathologic correlations and association with survival. J Surg Oncol 112 (2015), 430–435, 10.1002/jso.24012 [PubMed PMID: 26265374].
-
(2015)
J Surg Oncol
, vol.112
, pp. 430-435
-
-
Yang, M.1
Yu, Q.2
Liu, J.3
Fu, W.4
Cao, Y.5
Yu, L.6
-
24
-
-
84960413790
-
Programmed death-ligand 1 expression in muscle-invasive bladder cancer cystectomy specimens and lymph node metastasis: a reliable treatment selection biomarker?
-
[PubMed PMID: 26775720]
-
[24] Mukherji, D., Jabbour, M.N., Saroufim, M., Temraz, S., Nasr, R., Charafeddine, M., et al. Programmed death-ligand 1 expression in muscle-invasive bladder cancer cystectomy specimens and lymph node metastasis: a reliable treatment selection biomarker?. Clin Genitourin Cancer, 2015, 10.1016/j.clgc.2015.12.002 [PubMed PMID: 26775720].
-
(2015)
Clin Genitourin Cancer
-
-
Mukherji, D.1
Jabbour, M.N.2
Saroufim, M.3
Temraz, S.4
Nasr, R.5
Charafeddine, M.6
-
25
-
-
84925969186
-
Association of PD-L1 expression on tumor-infiltrating mononuclear cells and overall survival in patients with urothelial carcinoma
-
[PubMed PMID: 25600565]
-
[25] Bellmunt, J., Mullane, S.A., Werner, L., Fay, A.P., Callea, M., Leow, J.J., et al. Association of PD-L1 expression on tumor-infiltrating mononuclear cells and overall survival in patients with urothelial carcinoma. Ann Oncol 26 (2015), 812–817, 10.1093/annonc/mdv009 [PubMed PMID: 25600565].
-
(2015)
Ann Oncol
, vol.26
, pp. 812-817
-
-
Bellmunt, J.1
Mullane, S.A.2
Werner, L.3
Fay, A.P.4
Callea, M.5
Leow, J.J.6
-
26
-
-
51049096135
-
T-cell coregulatory molecule expression in urothelial cell carcinoma: clinicopathologic correlations and association with survival
-
[PubMed PMID: 18676751]
-
[26] Boorjian, S.A., Sheinin, Y., Crispen, P.L., Farmer, S.A., Lohse, C.M., Kuntz, S.M., et al. T-cell coregulatory molecule expression in urothelial cell carcinoma: clinicopathologic correlations and association with survival. Clin Cancer Res 14 (2008), 4800–4808, 10.1158/1078-0432.CCR-08-0731 [PubMed PMID: 18676751].
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4800-4808
-
-
Boorjian, S.A.1
Sheinin, Y.2
Crispen, P.L.3
Farmer, S.A.4
Lohse, C.M.5
Kuntz, S.M.6
-
27
-
-
77952337834
-
Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial
-
[PubMed PMID: 20460488; PMCID: PMC2919850]
-
[27] Carthon, B.C., Wolchok, J.D., Yuan, J., Kamat, A., Ng Tang, D.S., Sun, J., et al. Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res 16 (2010), 2861–2871, 10.1158/1078-0432.CCR-10-0569 [PubMed PMID: 20460488; PMCID: PMC2919850].
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2861-2871
-
-
Carthon, B.C.1
Wolchok, J.D.2
Yuan, J.3
Kamat, A.4
Ng Tang, D.S.5
Sun, J.6
-
28
-
-
84979763259
-
Molecular drivers of the non-T Cell-inflamed tumor microenvironment in urothelial bladder cancer
-
[PubMed PMID: 27197067]
-
[28] Sweis, R.F., Spranger, S., Bao, R., Paner, G.P., Stadler, W.M., Steinberg, G.D., et al. Molecular drivers of the non-T Cell-inflamed tumor microenvironment in urothelial bladder cancer. Cancer Immunol Res, 2016, 10.1158/2326-6066.CIR-15-0274 [PubMed PMID: 27197067].
-
(2016)
Cancer Immunol Res
-
-
Sweis, R.F.1
Spranger, S.2
Bao, R.3
Paner, G.P.4
Stadler, W.M.5
Steinberg, G.D.6
-
29
-
-
34247271873
-
CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma
-
[PubMed PMID: 17360461; PMCID: PMC1820692]
-
[29] Sharma, P., Shen, Y., Wen, S., Yamada, S., Jungbluth, A.A., Gnjatic, S., et al. CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma. Proc Natl Acad Sci U S A 104 (2007), 3967–3972, 10.1073/pnas.0611618104 [PubMed PMID: 17360461; PMCID: PMC1820692].
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3967-3972
-
-
Sharma, P.1
Shen, Y.2
Wen, S.3
Yamada, S.4
Jungbluth, A.A.5
Gnjatic, S.6
-
30
-
-
85047692172
-
Therapeutic vaccines for cancer: an overview of clinical trials
-
[PubMed PMID: 25001465]
-
[30] Melero, I., Gaudernack, G., Gerritsen, W., Huber, C., Parmiani, G., Scholl, S., et al. Therapeutic vaccines for cancer: an overview of clinical trials. Nat Rev Clin Oncol 11 (2014), 509–524, 10.1038/nrclinonc.2014.111 [PubMed PMID: 25001465].
-
(2014)
Nat Rev Clin Oncol
, vol.11
, pp. 509-524
-
-
Melero, I.1
Gaudernack, G.2
Gerritsen, W.3
Huber, C.4
Parmiani, G.5
Scholl, S.6
-
31
-
-
85029267560
-
Phase I study of patients with non-muscle invasive bladder cancer (NMIBC) treated with vesigenurtacel-L (HS-410) after Bacillus Calmette-Guérin (BCG)
-
[PubMed PMID: PMC4652496]
-
[31] Steinberg, G., Shore, N., Karsh, L., Bailen, J., Woods, M., Schreiber, T., et al. Phase I study of patients with non-muscle invasive bladder cancer (NMIBC) treated with vesigenurtacel-L (HS-410) after Bacillus Calmette-Guérin (BCG). J Immunother Cancer, 3(Suppl 2), 2015, P447, 10.1186/2051-1426-3-S2-P447 [PubMed PMID: PMC4652496].
-
(2015)
J Immunother Cancer
, vol.3
, pp. P447
-
-
Steinberg, G.1
Shore, N.2
Karsh, L.3
Bailen, J.4
Woods, M.5
Schreiber, T.6
-
32
-
-
84954493535
-
An open-label, randomized phase II trial of personalized peptide vaccination in patients with bladder cancer that progressed after platinum-based chemotherapy
-
[PubMed PMID: 26581246]
-
[32] Noguchi, M., Matsumoto, K., Uemura, H., Arai, G., Eto, M., Naito, S., et al. An open-label, randomized phase II trial of personalized peptide vaccination in patients with bladder cancer that progressed after platinum-based chemotherapy. Clin Cancer Res 22 (2016), 54–60, 10.1158/1078-0432.CCR-15-1265 [PubMed PMID: 26581246].
-
(2016)
Clin Cancer Res
, vol.22
, pp. 54-60
-
-
Noguchi, M.1
Matsumoto, K.2
Uemura, H.3
Arai, G.4
Eto, M.5
Naito, S.6
-
33
-
-
84938331362
-
Adoptive T cell immunotherapy for cancer
-
[PubMed PMID: 25717386; PMCID: PMC4327320]
-
[33] Perica, K., Varela, J.C., Oelke, M., Schneck, J., Adoptive T cell immunotherapy for cancer. Rambam Maimonides Med J, 6, 2015, e0004, 10.5041/RMMJ.10179 [PubMed PMID: 25717386; PMCID: PMC4327320].
-
(2015)
Rambam Maimonides Med J
, vol.6
, pp. e0004
-
-
Perica, K.1
Varela, J.C.2
Oelke, M.3
Schneck, J.4
-
34
-
-
84947577809
-
Pilot study of adoptive immunotherapy with sentinel node-derived T cells in muscle-invasive urinary bladder cancer
-
[PubMed PMID: 26144252
-
[34] Sherif, A., Hasan, M.N., Radecka, E., Rodriguez, A.L., Shabo, S., Karlsson, M., et al. Pilot study of adoptive immunotherapy with sentinel node-derived T cells in muscle-invasive urinary bladder cancer. Scand J Urol, 2015, 1–10, 10.3109/21681805.2015.1059880 [PubMed PMID: 26144252.
-
(2015)
Scand J Urol
, pp. 1-10
-
-
Sherif, A.1
Hasan, M.N.2
Radecka, E.3
Rodriguez, A.L.4
Shabo, S.5
Karlsson, M.6
-
35
-
-
84933510694
-
CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia
-
[PubMed PMID: 25999455; PMCID: PMC4481592]
-
[35] Maude, S.L., Teachey, D.T., Porter, D.L., Grupp, S.A., CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia. Blood 125 (2015), 4017–4023, 10.1182/blood-2014-12-580068 [PubMed PMID: 25999455; PMCID: PMC4481592].
-
(2015)
Blood
, vol.125
, pp. 4017-4023
-
-
Maude, S.L.1
Teachey, D.T.2
Porter, D.L.3
Grupp, S.A.4
-
36
-
-
84894459822
-
Diverse solid tumors expressing a restricted epitope of L1-CAM can be targeted by chimeric antigen receptor redirected T lymphocytes
-
[PubMed PMID: 24509172]
-
[36] Hong, H., Stastny, M., Brown, C., Chang, W.C., Ostberg, J.R., Forman, S.J., et al. Diverse solid tumors expressing a restricted epitope of L1-CAM can be targeted by chimeric antigen receptor redirected T lymphocytes. J Immunother 37 (2014), 93–104, 10.1097/CJI.0000000000000018 [PubMed PMID: 24509172].
-
(2014)
J Immunother
, vol.37
, pp. 93-104
-
-
Hong, H.1
Stastny, M.2
Brown, C.3
Chang, W.C.4
Ostberg, J.R.5
Forman, S.J.6
-
37
-
-
80051875696
-
Engineered T cells for pancreatic cancer treatment
-
[PubMed PMID: 21843265; PMCID: PMC3183449]
-
[37] Katari, U.L., Keirnan, J.M., Worth, A.C., Hodges, S.E., Leen, A.M., Fisher, W.E., et al. Engineered T cells for pancreatic cancer treatment. HPB (Oxford), 13, 2011, 643–650, 10.1111/j.1477–2574.2011.00344.x [PubMed PMID: 21843265; PMCID: PMC3183449].
-
(2011)
HPB (Oxford)
, vol.13
, pp. 643-650
-
-
Katari, U.L.1
Keirnan, J.M.2
Worth, A.C.3
Hodges, S.E.4
Leen, A.M.5
Fisher, W.E.6
-
38
-
-
84940824279
-
Oncolytic viruses: a new class of immunotherapy drugs
-
[PubMed PMID: 26323545]
-
[38] Kaufman, H.L., Kohlhapp, F.J., Zloza, A., Oncolytic viruses: a new class of immunotherapy drugs. Nat Rev Drug Discov 14 (2015), 642–662, 10.1038/nrd4663 [PubMed PMID: 26323545].
-
(2015)
Nat Rev Drug Discov
, vol.14
, pp. 642-662
-
-
Kaufman, H.L.1
Kohlhapp, F.J.2
Zloza, A.3
-
39
-
-
84869095632
-
A first in human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer
-
[PubMed PMID: 23088985]
-
[39] Burke, J.M., Lamm, D.L., Meng, M.V., Nemunaitis, J.J., Stephenson, J.J., Arseneau, J.C., et al. A first in human phase 1 study of CG0070, a GM-CSF expressing oncolytic adenovirus, for the treatment of nonmuscle invasive bladder cancer. J Urol 188 (2012), 2391–2397, 10.1016/j.juro.2012.07.097 [PubMed PMID: 23088985].
-
(2012)
J Urol
, vol.188
, pp. 2391-2397
-
-
Burke, J.M.1
Lamm, D.L.2
Meng, M.V.3
Nemunaitis, J.J.4
Stephenson, J.J.5
Arseneau, J.C.6
-
40
-
-
0031953814
-
p53 and RB expression predict progression in T1 bladder cancer
-
[PubMed PMID: 9563875]
-
[40] Grossman, H.B., Liebert, M., Antelo, M., Dinney, C.P., Hu, S.X., Palmer, J.L., et al. p53 and RB expression predict progression in T1 bladder cancer. Clin Cancer Res 4 (1998), 829–834 [PubMed PMID: 9563875].
-
(1998)
Clin Cancer Res
, vol.4
, pp. 829-834
-
-
Grossman, H.B.1
Liebert, M.2
Antelo, M.3
Dinney, C.P.4
Hu, S.X.5
Palmer, J.L.6
-
41
-
-
84918529219
-
In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer
-
[PubMed PMID: 25252918; PMCID: PMC4233185]
-
[41] Santos, M., Martínez-Fernández, M., Dueñas, M., García-Escudero, R., Alfaya, B., Villacampa, F., et al. In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer. Cancer Res 74 (2014), 6565–6577, 10.1158/0008-5472.CAN-14-1218 [PubMed PMID: 25252918; PMCID: PMC4233185].
-
(2014)
Cancer Res
, vol.74
, pp. 6565-6577
-
-
Santos, M.1
Martínez-Fernández, M.2
Dueñas, M.3
García-Escudero, R.4
Alfaya, B.5
Villacampa, F.6
-
42
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
[PubMed PMID: 8596936]
-
[42] Leach, D.R., Krummel, M.F., Allison, J.P., Enhancement of antitumor immunity by CTLA-4 blockade. Science 271 (1996), 1734–1736 [PubMed PMID: 8596936].
-
(1996)
Science
, vol.271
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
43
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
[PubMed PMID: 20525992; PMCID: PMC3549297]
-
[43] Hodi, F.S., O'Day, S.J., McDermott, D.F., Weber, R.W., Sosman, J.A., Haanen, J.B., et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363 (2010), 711–723, 10.1056/NEJMoa1003466 [PubMed PMID: 20525992; PMCID: PMC3549297].
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
44
-
-
84928917822
-
Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma
-
[PubMed PMID: 25667295]
-
[44] Schadendorf, D., Hodi, F.S., Robert, C., Weber, J.S., Margolin, K., Hamid, O., et al. Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma. J Clin Oncol 33 (2015), 1889–1894, 10.1200/JCO.2014.56.2736 [PubMed PMID: 25667295].
-
(2015)
J Clin Oncol
, vol.33
, pp. 1889-1894
-
-
Schadendorf, D.1
Hodi, F.S.2
Robert, C.3
Weber, J.S.4
Margolin, K.5
Hamid, O.6
-
45
-
-
84859153479
-
Raising the bar: the curative potential of human cancer immunotherapy
-
[PubMed PMID: 22461638]
-
[45] Rosenberg, S.A., Raising the bar: the curative potential of human cancer immunotherapy. Sci Transl Med, 4, 2012, 127ps8, 10.1126/scitranslmed.3003634 [PubMed PMID: 22461638].
-
(2012)
Sci Transl Med
, vol.4
, pp. 127ps8
-
-
Rosenberg, S.A.1
-
46
-
-
54449091476
-
CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients
-
[PubMed PMID: 18818309; PMCID: PMC2567480]
-
[46] Liakou, C.I., Kamat, A., Tang, D.N., Chen, H., Sun, J., Troncoso, P., et al. CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients. Proc Natl Acad Sci U S A 105 (2008), 14987–14992, 10.1073/pnas.0806075105 [PubMed PMID: 18818309; PMCID: PMC2567480].
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14987-14992
-
-
Liakou, C.I.1
Kamat, A.2
Tang, D.N.3
Chen, H.4
Sun, J.5
Troncoso, P.6
-
47
-
-
84928774156
-
The future of immune checkpoint therapy
-
[PubMed PMID: 25838373]
-
[47] Sharma, P., Allison, J.P., The future of immune checkpoint therapy. Science 348 (2015), 56–61, 10.1126/science.aaa8172 [PubMed PMID: 25838373].
-
(2015)
Science
, vol.348
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
-
48
-
-
85029269598
-
Efficacy of anti-ICOS agonist monoclonal antibodies in preclinical tumor models provides a rationale for clinical development as cancer immunotherapeutics
-
[PubMed PMID: PMC4645516]
-
[48] Harvey, C., Elpek, K., Duong, E., Simpson, T., Shu, C.J., Shallberg, L., et al. Efficacy of anti-ICOS agonist monoclonal antibodies in preclinical tumor models provides a rationale for clinical development as cancer immunotherapeutics. J Immunother Cancer, 3(Suppl 2), 2015, O9, 10.1186/2051-1426-3-S2-O9 [PubMed PMID: PMC4645516].
-
(2015)
J Immunother Cancer
, vol.3
, pp. O9
-
-
Harvey, C.1
Elpek, K.2
Duong, E.3
Simpson, T.4
Shu, C.J.5
Shallberg, L.6
-
49
-
-
84959224461
-
Phase II trial of gemcitabine+cisplatin+ipilimumab in patients with metastatic urothelial cancer
-
[49] Galsky, M.D., Hahn, N.M., Albany, C., Fleming, M.T., Starodub, A., Twardowski, P., et al. Phase II trial of gemcitabine+cisplatin+ipilimumab in patients with metastatic urothelial cancer. ASCO Meet Abstr, 34(Suppl 2), 2016, 357.
-
(2016)
ASCO Meet Abstr
, vol.34
, pp. 357
-
-
Galsky, M.D.1
Hahn, N.M.2
Albany, C.3
Fleming, M.T.4
Starodub, A.5
Twardowski, P.6
-
50
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
[PubMed PMID: 23724846; PMCID: PMC4126516]
-
[50] Hamid, O., Robert, C., Daud, A., Hodi, F.S., Hwu, W.J., Kefford, R., et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med. 369 (2013), 134–144, 10.1056/NEJMoa1305133 [PubMed PMID: 23724846; PMCID: PMC4126516].
-
(2013)
N Engl J Med.
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
51
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
[PubMed PMID: 26028407]
-
[51] Brahmer, J., Reckamp, K.L., Baas, P., Crinò, L., Eberhardt, W.E., Poddubskaya, E., et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med 373 (2015), 123–135, 10.1056/NEJMoa1504627 [PubMed PMID: 26028407].
-
(2015)
N Engl J Med
, vol.373
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
Crinò, L.4
Eberhardt, W.E.5
Poddubskaya, E.6
-
52
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
[PubMed PMID: 26406148]
-
[52] Motzer, R.J., Escudier, B., McDermott, D.F., George, S., Hammers, H.J., Srinivas, S., et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N Engl J Med 373 (2015), 1803–1813, 10.1056/NEJMoa1510665 [PubMed PMID: 26406148].
-
(2015)
N Engl J Med
, vol.373
, pp. 1803-1813
-
-
Motzer, R.J.1
Escudier, B.2
McDermott, D.F.3
George, S.4
Hammers, H.J.5
Srinivas, S.6
-
53
-
-
84947267135
-
Pembrolizumab (MK-3475) for advanced urothelial cancer: updated results and biomarker analysis from KEYNOTE-012
-
[53] Plimack, E.R., Bellmunt, J., Gupta, S., Berger, R., Montgomery, R.B., Heath, K., et al. Pembrolizumab (MK-3475) for advanced urothelial cancer: updated results and biomarker analysis from KEYNOTE-012. ASCO Meet Abstr, 33(Suppl 15), 2015, 4502.
-
(2015)
ASCO Meet Abstr
, vol.33
, pp. 4502
-
-
Plimack, E.R.1
Bellmunt, J.2
Gupta, S.3
Berger, R.4
Montgomery, R.B.5
Heath, K.6
-
54
-
-
84959577118
-
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial
-
[PubMed PMID: 26952546]
-
[54] Rosenberg, J.E., Hoffman-Censits, J., Powles, T., van der Heijden, M.S., Balar, A.V., Necchi, A., et al. Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial. Lancet, 2016, 10.1016/S0140-6736(16)00561-4 [PubMed PMID: 26952546].
-
(2016)
Lancet
-
-
Rosenberg, J.E.1
Hoffman-Censits, J.2
Powles, T.3
van der Heijden, M.S.4
Balar, A.V.5
Necchi, A.6
-
55
-
-
84925545111
-
Clinical blockade of PD1 and LAG3—potential mechanisms of action
-
[PubMed PMID: 25534622]
-
[55] Nguyen, L.T., Ohashi, P.S., Clinical blockade of PD1 and LAG3—potential mechanisms of action. Nat Rev Immunol 15 (2015), 45–56, 10.1038/nri3790 [PubMed PMID: 25534622].
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 45-56
-
-
Nguyen, L.T.1
Ohashi, P.S.2
-
56
-
-
84922391334
-
Tim-3: an emerging target in the cancer immunotherapy landscape
-
[PubMed PMID: 24795351]
-
[56] Anderson, A.C., Tim-3: an emerging target in the cancer immunotherapy landscape. Cancer Immunol Res 2 (2014), 393–398, 10.1158/2326-6066.CIR-14-0039 [PubMed PMID: 24795351].
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 393-398
-
-
Anderson, A.C.1
-
57
-
-
84863393290
-
CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1
-
[PubMed PMID: 22205715; PMCID: PMC3288235]
-
[57] Fourcade, J., Sun, Z., Pagliano, O., Guillaume, P., Luescher, I.F., Sander, C., et al. CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1. Cancer Res 72 (2012), 887–896, 10.1158/0008-5472.CAN-11-2637 [PubMed PMID: 22205715; PMCID: PMC3288235].
-
(2012)
Cancer Res
, vol.72
, pp. 887-896
-
-
Fourcade, J.1
Sun, Z.2
Pagliano, O.3
Guillaume, P.4
Luescher, I.F.5
Sander, C.6
-
58
-
-
84990001695
-
VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy
-
[PubMed PMID: 24894088; PMCID: PMC4085258]
-
[58] Lines, J.L., Sempere, L.F., Broughton, T., Wang, L., Noelle, R., VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy. Cancer Immunol Res 2 (2014), 510–517, 10.1158/2326-6066.CIR-14-0072 [PubMed PMID: 24894088; PMCID: PMC4085258].
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 510-517
-
-
Lines, J.L.1
Sempere, L.F.2
Broughton, T.3
Wang, L.4
Noelle, R.5
-
59
-
-
84940378016
-
Agonists of co-stimulation in cancer immunotherapy directed against CD137, OX40, GITR, CD27, CD28, and ICOS
-
[PubMed PMID: 26320067]
-
[59] Sanmamed, M.F., Pastor, F., Rodriguez, A., Perez-Gracia, J.L., Rodriguez-Ruiz, M.E., Jure-Kunkel, M., et al. Agonists of co-stimulation in cancer immunotherapy directed against CD137, OX40, GITR, CD27, CD28, and ICOS. Semin Oncol 42 (2015), 640–655, 10.1053/j.seminoncol.2015.05.014 [PubMed PMID: 26320067].
-
(2015)
Semin Oncol
, vol.42
, pp. 640-655
-
-
Sanmamed, M.F.1
Pastor, F.2
Rodriguez, A.3
Perez-Gracia, J.L.4
Rodriguez-Ruiz, M.E.5
Jure-Kunkel, M.6
-
60
-
-
77955515915
-
Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy
-
[PubMed PMID: 20480365]
-
[60] Coe, D., Begom, S., Addey, C., White, M., Dyson, J., Chai, J.G., Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy. Cancer Immunol Immunother 59 (2010), 1367–1377, 10.1007/s00262-010-0866-5 [PubMed PMID: 20480365].
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1367-1377
-
-
Coe, D.1
Begom, S.2
Addey, C.3
White, M.4
Dyson, J.5
Chai, J.G.6
-
61
-
-
0142137237
-
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
-
[PubMed PMID: 14502282]
-
[61] Uyttenhove, C., Pilotte, L., Théate, I., Stroobant, V., Colau, D., Parmentier, N., et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med 9 (2003), 1269–1274, 10.1038/nm934 [PubMed PMID: 14502282].
-
(2003)
Nat Med
, vol.9
, pp. 1269-1274
-
-
Uyttenhove, C.1
Pilotte, L.2
Théate, I.3
Stroobant, V.4
Colau, D.5
Parmentier, N.6
-
62
-
-
84954093852
-
Molecular pathways: targeting IDO1 and other tryptophan dioxygenases for cancer immunotherapy
-
[PubMed PMID: 26519060; PMCID: PMC4681601]
-
[62] Zhai, L., Spranger, S., Binder, D.C., Gritsina, G., Lauing, K.L., Giles, F.J., et al. Molecular pathways: targeting IDO1 and other tryptophan dioxygenases for cancer immunotherapy. Clin Cancer Res 21 (2015), 5427–5433, 10.1158/1078-0432.CCR-15-0420 [PubMed PMID: 26519060; PMCID: PMC4681601].
-
(2015)
Clin Cancer Res
, vol.21
, pp. 5427-5433
-
-
Zhai, L.1
Spranger, S.2
Binder, D.C.3
Gritsina, G.4
Lauing, K.L.5
Giles, F.J.6
-
63
-
-
84995684655
-
Preliminary results from a Phase I/II study of epacadostat (incb024360) in combination with pembrolizumab in patients with selected advanced cancers
-
[PubMed PMID: PMC4645566]
-
[63] Gangadhar, T.C., Hamid, O., Smith, D.C., Bauer, T.M., Wasser, J.S., Luke, J.J., et al. Preliminary results from a Phase I/II study of epacadostat (incb024360) in combination with pembrolizumab in patients with selected advanced cancers. J Immunother Cancer, 3(Suppl 2), 2015, O7, 10.1186/2051-1426-3-S2-O7 [PubMed PMID: PMC4645566].
-
(2015)
J Immunother Cancer
, vol.3
, pp. O7
-
-
Gangadhar, T.C.1
Hamid, O.2
Smith, D.C.3
Bauer, T.M.4
Wasser, J.S.5
Luke, J.J.6
-
64
-
-
84883863501
-
Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells
-
[PubMed PMID: 23986400; PMCID: PMC4136707]
-
[64] Spranger, S., Spaapen, R.M., Zha, Y., Williams, J., Meng, Y., Ha, T.T., et al. Up-regulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8(+) T cells. Sci Transl Med, 5, 2013, 200ra116, 10.1126/scitranslmed.3006504 [PubMed PMID: 23986400; PMCID: PMC4136707].
-
(2013)
Sci Transl Med
, vol.5
, pp. 200ra116
-
-
Spranger, S.1
Spaapen, R.M.2
Zha, Y.3
Williams, J.4
Meng, Y.5
Ha, T.T.6
-
65
-
-
84886698315
-
Innate and adaptive immune cells in the tumor microenvironment
-
[PubMed PMID: 24048123; PMCID: PMC4118725]
-
[65] Gajewski, T.F., Schreiber, H., Fu, Y.X., Innate and adaptive immune cells in the tumor microenvironment. Nat Immunol 14 (2013), 1014–1022, 10.1038/ni.2703 [PubMed PMID: 24048123; PMCID: PMC4118725].
-
(2013)
Nat Immunol
, vol.14
, pp. 1014-1022
-
-
Gajewski, T.F.1
Schreiber, H.2
Fu, Y.X.3
-
66
-
-
77958012775
-
Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy
-
[PubMed PMID: 20693853]
-
[66] Gajewski, T.F., Louahed, J., Brichard, V.G., Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy. Cancer J 16 (2010), 399–403, 10.1097/PPO.0b013e3181eacbd8 [PubMed PMID: 20693853].
-
(2010)
Cancer J
, vol.16
, pp. 399-403
-
-
Gajewski, T.F.1
Louahed, J.2
Brichard, V.G.3
-
67
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
[PubMed PMID: 25428505; PMCID: PMC4246418]
-
[67] Tumeh, P.C., Harview, C.L., Yearley, J.H., Shintaku, I.P., Taylor, E.J., Robert, L., et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 515 (2014), 568–571, 10.1038/nature13954 [PubMed PMID: 25428505; PMCID: PMC4246418].
-
(2014)
Nature
, vol.515
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
Shintaku, I.P.4
Taylor, E.J.5
Robert, L.6
-
68
-
-
84936953099
-
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
-
[PubMed PMID: 25970248]
-
[68] Spranger, S., Bao, R., Gajewski, T.F., Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity. Nature 523 (2015), 231–235, 10.1038/nature14404 [PubMed PMID: 25970248].
-
(2015)
Nature
, vol.523
, pp. 231-235
-
-
Spranger, S.1
Bao, R.2
Gajewski, T.F.3
-
69
-
-
84957093642
-
Loss of PTEN promotes resistance to T Cell-mediated immunotherapy
-
[PubMed PMID: 26645196; PMCID: PMC4744499]
-
[69] Peng, W., Chen, J.Q., Liu, C., Malu, S., Creasy, C., Tetzlaff, M.T., et al. Loss of PTEN promotes resistance to T Cell-mediated immunotherapy. Cancer Discov 6 (2016), 202–216, 10.1158/2159-8290.CD-15-0283 [PubMed PMID: 26645196; PMCID: PMC4744499].
-
(2016)
Cancer Discov
, vol.6
, pp. 202-216
-
-
Peng, W.1
Chen, J.Q.2
Liu, C.3
Malu, S.4
Creasy, C.5
Tetzlaff, M.T.6
-
70
-
-
84912120595
-
STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors
-
[PubMed PMID: 25517615; PMCID: PMC4384884]
-
[70] Woo, S.R., Fuertes, M.B., Corrales, L., Spranger, S., Furdyna, M.J., Leung, M.Y., et al. STING-dependent cytosolic DNA sensing mediates innate immune recognition of immunogenic tumors. Immunity 41 (2014), 830–842, 10.1016/j.immuni.2014.10.017 [PubMed PMID: 25517615; PMCID: PMC4384884].
-
(2014)
Immunity
, vol.41
, pp. 830-842
-
-
Woo, S.R.1
Fuertes, M.B.2
Corrales, L.3
Spranger, S.4
Furdyna, M.J.5
Leung, M.Y.6
-
71
-
-
84947217032
-
Molecular pathways: targeting the stimulator of interferon genes (STING) in the immunotherapy of cancer
-
[PubMed PMID: 26373573; PMCID: PMC4750108]
-
[71] Corrales, L., Gajewski, T.F., Molecular pathways: targeting the stimulator of interferon genes (STING) in the immunotherapy of cancer. Clin Cancer Res 21 (2015), 4774–4779, 10.1158/1078-0432.CCR-15-1362 [PubMed PMID: 26373573; PMCID: PMC4750108].
-
(2015)
Clin Cancer Res
, vol.21
, pp. 4774-4779
-
-
Corrales, L.1
Gajewski, T.F.2
-
72
-
-
84926528926
-
The STING pathway and the T cell-inflamed tumor microenvironment
-
[PubMed PMID: 25758021; PMCID: PMC4393801]
-
[72] Woo, S.R., Corrales, L., Gajewski, T.F., The STING pathway and the T cell-inflamed tumor microenvironment. Trends Immunol 36 (2015), 250–256, 10.1016/j.it.2015.02.003 [PubMed PMID: 25758021; PMCID: PMC4393801].
-
(2015)
Trends Immunol
, vol.36
, pp. 250-256
-
-
Woo, S.R.1
Corrales, L.2
Gajewski, T.F.3
-
73
-
-
84948451779
-
Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
-
[PubMed PMID: 26541606]
-
[73] Sivan, A., Corrales, L., Hubert, N., Williams, J.B., Aquino-Michaels, K., Earley, Z.M., et al. Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy. Science 350 (2015), 1084–1089, 10.1126/science.aac4255 [PubMed PMID: 26541606].
-
(2015)
Science
, vol.350
, pp. 1084-1089
-
-
Sivan, A.1
Corrales, L.2
Hubert, N.3
Williams, J.B.4
Aquino-Michaels, K.5
Earley, Z.M.6
-
74
-
-
84940372582
-
The next hurdle in cancer immunotherapy: overcoming the non-T-cell-inflamed tumor microenvironment
-
[PubMed PMID: 26320069; PMCID: PMC4555998]
-
[74] Gajewski, T.F., The next hurdle in cancer immunotherapy: overcoming the non-T-cell-inflamed tumor microenvironment. Semin Oncol 42 (2015), 663–671, 10.1053/j.seminoncol.2015.05.011 [PubMed PMID: 26320069; PMCID: PMC4555998].
-
(2015)
Semin Oncol
, vol.42
, pp. 663-671
-
-
Gajewski, T.F.1
-
75
-
-
84989918072
-
Safety and efficacy of durvalumab (MEDI4736), an anti-programmed cell death ligand-1 immune checkpoint inhibitor, in patients with advanced urothelial bladder cancer
-
[PubMed PMID: 27269937]
-
[75] Massard, C., Gordon, M.S., Sharma, S., Rafii, S., Wainberg, Z.A., Luke, J., et al. Safety and efficacy of durvalumab (MEDI4736), an anti-programmed cell death ligand-1 immune checkpoint inhibitor, in patients with advanced urothelial bladder cancer. J Clin Oncol, 2016, 10.1200/JCO.2016.67.9761 [PubMed PMID: 27269937].
-
(2016)
J Clin Oncol
-
-
Massard, C.1
Gordon, M.S.2
Sharma, S.3
Rafii, S.4
Wainberg, Z.A.5
Luke, J.6
-
76
-
-
84936821508
-
Association of response to programmed death receptor 1 (PD-1) blockade with pembrolizumab (MK-3475) with an interferon-inflammatory immune gene signature
-
[76] Ribas, A., Robert, C., Hodi, F.S., Wolchok, J.D., Joshua, A.M., Hwu, W.-J., et al. Association of response to programmed death receptor 1 (PD-1) blockade with pembrolizumab (MK-3475) with an interferon-inflammatory immune gene signature. ASCO Meet Abstr, 33(Suppl 15), 2015, 3001.
-
(2015)
ASCO Meet Abstr
, vol.33
, pp. 3001
-
-
Ribas, A.1
Robert, C.2
Hodi, F.S.3
Wolchok, J.D.4
Joshua, A.M.5
Hwu, W.-J.6
-
77
-
-
84941108977
-
Inflamed-phenotype gene expression signatures to predict benefit from the anti-PD-1 antibody pembrolizumab in PD-L1+head and neck cancer patients
-
[77] Seiwert, T.Y., Burtness, B., Weiss, J., Eder, J.P., Yearley, J., Murphy, E., et al. Inflamed-phenotype gene expression signatures to predict benefit from the anti-PD-1 antibody pembrolizumab in PD-L1+head and neck cancer patients. ASCO Meet Abstr, 33(Suppl 15), 2015, 6017.
-
(2015)
ASCO Meet Abstr
, vol.33
, pp. 6017
-
-
Seiwert, T.Y.1
Burtness, B.2
Weiss, J.3
Eder, J.P.4
Yearley, J.5
Murphy, E.6
-
78
-
-
84918828514
-
Genetic basis for clinical response to CTLA-4 blockade in melanoma
-
[PubMed PMID: 25409260; PMCID: PMC4315319]
-
[78] Snyder, A., Makarov, V., Merghoub, T., Yuan, J., Zaretsky, J.M., Desrichard, A., et al. Genetic basis for clinical response to CTLA-4 blockade in melanoma. N Engl J Med 371 (2014), 2189–2399, 10.1056/NEJMoa1406498 [PubMed PMID: 25409260; PMCID: PMC4315319].
-
(2014)
N Engl J Med
, vol.371
, pp. 2189-2399
-
-
Snyder, A.1
Makarov, V.2
Merghoub, T.3
Yuan, J.4
Zaretsky, J.M.5
Desrichard, A.6
-
79
-
-
84928761118
-
Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
-
[PubMed PMID: 25765070]
-
[79] Rizvi, N.A., Hellmann, M.D., Snyder, A., Kvistborg, P., Makarov, V., Havel, J.J., et al. Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer. Science 348 (2015), 124–128, 10.1126/science.aaa1348 [PubMed PMID: 25765070].
-
(2015)
Science
, vol.348
, pp. 124-128
-
-
Rizvi, N.A.1
Hellmann, M.D.2
Snyder, A.3
Kvistborg, P.4
Makarov, V.5
Havel, J.J.6
-
80
-
-
84932628341
-
PD-1 blockade in tumors with mismatch-repair deficiency
-
[PubMed PMID: 26028255; PMCID: PMC4481136]
-
[80] Le, D.T., Uram, J.N., Wang, H., Bartlett, B.R., Kemberling, H., Eyring, A.D., et al. PD-1 blockade in tumors with mismatch-repair deficiency. N Engl J Med 372 (2015), 2509–2520, 10.1056/NEJMoa1500596 [PubMed PMID: 26028255; PMCID: PMC4481136].
-
(2015)
N Engl J Med
, vol.372
, pp. 2509-2520
-
-
Le, D.T.1
Uram, J.N.2
Wang, H.3
Bartlett, B.R.4
Kemberling, H.5
Eyring, A.D.6
-
81
-
-
84920921528
-
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
-
[PubMed PMID: 25428507; PMCID: PMC4279952]
-
[81] Gubin, M.M., Zhang, X., Schuster, H., Caron, E., Ward, J.P., Noguchi, T., et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 515 (2014), 577–581, 10.1038/nature13988 [PubMed PMID: 25428507; PMCID: PMC4279952].
-
(2014)
Nature
, vol.515
, pp. 577-581
-
-
Gubin, M.M.1
Zhang, X.2
Schuster, H.3
Caron, E.4
Ward, J.P.5
Noguchi, T.6
-
82
-
-
84920956731
-
Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
-
[PubMed PMID: 25428506]
-
[82] Yadav, M., Jhunjhunwala, S., Phung, Q.T., Lupardus, P., Tanguay, J., Bumbaca, S., et al. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature 515 (2014), 572–576, 10.1038/nature14001 [PubMed PMID: 25428506].
-
(2014)
Nature
, vol.515
, pp. 572-576
-
-
Yadav, M.1
Jhunjhunwala, S.2
Phung, Q.T.3
Lupardus, P.4
Tanguay, J.5
Bumbaca, S.6
-
83
-
-
84885340198
-
Immunosequencing: applications of immune repertoire deep sequencing
-
[PubMed PMID: 24140071]
-
[83] Robins, H., Immunosequencing: applications of immune repertoire deep sequencing. Curr Opin Immunol 25 (2013), 646–652, 10.1016/j.coi.2013.09.017 [PubMed PMID: 24140071].
-
(2013)
Curr Opin Immunol
, vol.25
, pp. 646-652
-
-
Robins, H.1
-
84
-
-
84890140713
-
TCR repertoires of intratumoral T-cell subsets
-
[PubMed PMID: 24329790]
-
[84] Linnemann, C., Mezzadra, R., Schumacher, T.N., TCR repertoires of intratumoral T-cell subsets. Immunol Rev 257 (2014), 72–82, 10.1111/imr.12140 [PubMed PMID: 24329790].
-
(2014)
Immunol Rev
, vol.257
, pp. 72-82
-
-
Linnemann, C.1
Mezzadra, R.2
Schumacher, T.N.3
-
85
-
-
84952637397
-
T-cell receptor profiling in cancer
-
[PubMed PMID: 26404496]
-
[85] Kirsch, I., Vignali, M., Robins, H., T-cell receptor profiling in cancer. Mol Oncol 9 (2015), 2063–2070, 10.1016/j.molonc.2015.09.003 [PubMed PMID: 26404496].
-
(2015)
Mol Oncol
, vol.9
, pp. 2063-2070
-
-
Kirsch, I.1
Vignali, M.2
Robins, H.3
-
86
-
-
84995387448
-
Low T-cell receptor diversity, high somatic mutation burden, and high neoantigen load as predictors of clinical outcome in muscle-invasive bladder cancer
-
[86] Choudhury, N.J., Kiyotani, K., Yap, K.L., et al. Low T-cell receptor diversity, high somatic mutation burden, and high neoantigen load as predictors of clinical outcome in muscle-invasive bladder cancer. Eur Urol Focus 2 (2016), 445–452, 10.1016/j.euf.2015.09.007.
-
(2016)
Eur Urol Focus
, vol.2
, pp. 445-452
-
-
Choudhury, N.J.1
Kiyotani, K.2
Yap, K.L.3
-
87
-
-
84893520397
-
Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy
-
[PubMed PMID: 24525232; PMCID: PMC4011497]
-
[87] Choi, W., Porten, S., Kim, S., Willis, D., Plimack, E.R., Hoffman-Censits, J., et al. Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell 25 (2014), 152–165, 10.1016/j.ccr.2014.01.009 [PubMed PMID: 24525232; PMCID: PMC4011497].
-
(2014)
Cancer Cell
, vol.25
, pp. 152-165
-
-
Choi, W.1
Porten, S.2
Kim, S.3
Willis, D.4
Plimack, E.R.5
Hoffman-Censits, J.6
-
88
-
-
84896844735
-
Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology
-
[PubMed PMID: 24520177; PMCID: PMC3939870]
-
[88] Damrauer, J.S., Hoadley, K.A., Chism, D.D., Fan, C., Tiganelli, C.J., Wobker, S.E., et al. Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology. Proc Natl Acad Sci U S A 111 (2014), 3110–3115, 10.1073/pnas.1318376111 [PubMed PMID: 24520177; PMCID: PMC3939870].
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 3110-3115
-
-
Damrauer, J.S.1
Hoadley, K.A.2
Chism, D.D.3
Fan, C.4
Tiganelli, C.J.5
Wobker, S.E.6
-
89
-
-
84927130807
-
Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential
-
[PubMed PMID: 25860605]
-
[89] Sharma, P., Allison, J.P., Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential. Cell 161 (2015), 205–214, 10.1016/j.cell.2015.03.030 [PubMed PMID: 25860605].
-
(2015)
Cell
, vol.161
, pp. 205-214
-
-
Sharma, P.1
Allison, J.P.2
|