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Volumn 257, Issue 1, 2014, Pages 72-82

TCR repertoires of intratumoral T-cell subsets

Author keywords

Cancer exome; Gene therapy; Immunotherapy; MHC multimer; T cell; TCR

Indexed keywords

EPITOPE; MINOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR ANTIGEN;

EID: 84890140713     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/imr.12140     Document Type: Article
Times cited : (57)

References (63)
  • 2
    • 84882837534 scopus 로고    scopus 로고
    • Signatures of mutational processes in human cancer
    • Alexandrov LB, et al. Signatures of mutational processes in human cancer. Nature 2013;500:415-421.
    • (2013) Nature , vol.500 , pp. 415-421
    • Alexandrov, L.B.1
  • 4
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: impact on clinical outcome
    • Fridman WH, Pages F, Sautes-Fridman C, Galon J. The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 2012;12:298-306.
    • (2012) Nat Rev Cancer , vol.12 , pp. 298-306
    • Fridman, W.H.1    Pages, F.2    Sautes-Fridman, C.3    Galon, J.4
  • 5
    • 0028316911 scopus 로고
    • Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor
    • Kawakami Y, et al. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc Natl Acad Sci USA 1994;91:3515-3519.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3515-3519
    • Kawakami, Y.1
  • 6
    • 0028298174 scopus 로고
    • Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection
    • Kawakami Y, et al. Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc Natl Acad Sci USA 1994;91:6458-6462.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6458-6462
    • Kawakami, Y.1
  • 7
    • 0028906594 scopus 로고
    • Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes
    • Wang RF, Robbins PF, Kawakami Y, Kang XQ, Rosenberg SA. Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. J Exp Med 1995;181:799-804.
    • (1995) J Exp Med , vol.181 , pp. 799-804
    • Wang, R.F.1    Robbins, P.F.2    Kawakami, Y.3    Kang, X.Q.4    Rosenberg, S.A.5
  • 9
    • 0035412374 scopus 로고    scopus 로고
    • Molecular and flow cytometric analysis of the Vbeta repertoire for clonality assessment in mature TCRalphabeta T-cell proliferations
    • Langerak AW, et al. Molecular and flow cytometric analysis of the Vbeta repertoire for clonality assessment in mature TCRalphabeta T-cell proliferations. Blood 2001;98:165-173.
    • (2001) Blood , vol.98 , pp. 165-173
    • Langerak, A.W.1
  • 10
    • 0028220953 scopus 로고
    • Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping. Correlation with immune status
    • Gorski J, et al. Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping. Correlation with immune status. J Immunol 1994;152:5109-5119.
    • (1994) J Immunol , vol.152 , pp. 5109-5119
    • Gorski, J.1
  • 11
    • 84868154295 scopus 로고    scopus 로고
    • Next generation sequencing for TCR repertoire profiling: platform-specific features and correction algorithms
    • Bolotin DA, et al. Next generation sequencing for TCR repertoire profiling: platform-specific features and correction algorithms. Eur J Immunol 2012;42:3073-3083.
    • (2012) Eur J Immunol , vol.42 , pp. 3073-3083
    • Bolotin, D.A.1
  • 12
    • 77950541195 scopus 로고    scopus 로고
    • Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells
    • Robins HS, et al. Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells. Blood 2009;114:4099-4107.
    • (2009) Blood , vol.114 , pp. 4099-4107
    • Robins, H.S.1
  • 13
    • 84875228084 scopus 로고    scopus 로고
    • Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation
    • van Heijst JW, et al. Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation. Nat Med 2013;19:372-377.
    • (2013) Nat Med , vol.19 , pp. 372-377
    • van Heijst, J.W.1
  • 14
    • 84883466251 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue
    • Sherwood AM, et al. Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue. Cancer Immunol Immunother 2013;62:1453-1461.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1453-1461
    • Sherwood, A.M.1
  • 15
    • 84887167328 scopus 로고    scopus 로고
    • High-throughput sequencing of T cell receptors reveals a homogeneous repertoire of tumor-infiltrating lymphocytes in ovarian cancer
    • doi: 10.1002/path.4260.
    • Emerson RO, et al. High-throughput sequencing of T cell receptors reveals a homogeneous repertoire of tumor-infiltrating lymphocytes in ovarian cancer. J Pathol 2013:doi: 10.1002/path.4260.
    • (2013) J Pathol
    • Emerson, R.O.1
  • 17
    • 59849100381 scopus 로고    scopus 로고
    • Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy
    • Tran KQ, et al. Minimally cultured tumor-infiltrating lymphocytes display optimal characteristics for adoptive cell therapy. J Immunother 2008;31:742-751.
    • (2008) J Immunother , vol.31 , pp. 742-751
    • Tran, K.Q.1
  • 18
    • 0024390061 scopus 로고
    • Tumor-specific cytolysis by lymphocytes infiltrating human melanomas
    • Topalian SL, Solomon D, Rosenberg SA. Tumor-specific cytolysis by lymphocytes infiltrating human melanomas. J Immunol 1989;142:3714-3725.
    • (1989) J Immunol , vol.142 , pp. 3714-3725
    • Topalian, S.L.1    Solomon, D.2    Rosenberg, S.A.3
  • 19
    • 0023093741 scopus 로고
    • Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma
    • Muul LM, Spiess PJ, Director EP, Rosenberg SA. Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma. J Immunol 1987;138:989-995.
    • (1987) J Immunol , vol.138 , pp. 989-995
    • Muul, L.M.1    Spiess, P.J.2    Director, E.P.3    Rosenberg, S.A.4
  • 20
    • 0024510298 scopus 로고
    • Tumour-infiltrating lymphocytes and interleukin-2 in treatment of advanced cancer
    • Kradin RL, et al. Tumour-infiltrating lymphocytes and interleukin-2 in treatment of advanced cancer. Lancet 1989;1:577-580.
    • (1989) Lancet , vol.1 , pp. 577-580
    • Kradin, R.L.1
  • 21
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley ME, et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 2002;298:850-854.
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1
  • 22
    • 33750324618 scopus 로고    scopus 로고
    • Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes
    • Johnson LA, et al. Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes. J Immunol 2006;177:6548-6559.
    • (2006) J Immunol , vol.177 , pp. 6548-6559
    • Johnson, L.A.1
  • 23
    • 20844448391 scopus 로고    scopus 로고
    • Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions
    • Hughes MS, et al. Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions. Hum Gene Ther 2005;16:457-472.
    • (2005) Hum Gene Ther , vol.16 , pp. 457-472
    • Hughes, M.S.1
  • 24
    • 0028815876 scopus 로고
    • Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen
    • Cole DJ, et al. Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen. Cancer Res 1995;55:748-752.
    • (1995) Cancer Res , vol.55 , pp. 748-752
    • Cole, D.J.1
  • 25
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan RA, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006;314:126-129.
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1
  • 26
    • 70149114880 scopus 로고    scopus 로고
    • Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
    • Johnson LA, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009;114:535-546.
    • (2009) Blood , vol.114 , pp. 535-546
    • Johnson, L.A.1
  • 27
    • 84876862578 scopus 로고    scopus 로고
    • MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy
    • Dossinger G, et al. MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy. PLoS ONE 2013;8:e61384.
    • (2013) PLoS ONE , vol.8
    • Dossinger, G.1
  • 28
    • 84859485913 scopus 로고    scopus 로고
    • T cell receptor alphabeta diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection
    • Wang GC, Dash P, McCullers JA, Doherty PC, Thomas PG. T cell receptor alphabeta diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection. Sci Transl Med 2012;4:128ra142.
    • (2012) Sci Transl Med , vol.4
    • Wang, G.C.1    Dash, P.2    McCullers, J.A.3    Doherty, P.C.4    Thomas, P.G.5
  • 29
    • 84887453773 scopus 로고    scopus 로고
    • High-throughput identification of antigen-specific TCRs by TCR gene capture
    • Linnemann C, et al. High-throughput identification of antigen-specific TCRs by TCR gene capture. Nat Med 2013;19:1534-1541.
    • (2013) Nat Med , vol.19 , pp. 1534-1541
    • Linnemann, C.1
  • 30
    • 84881640374 scopus 로고    scopus 로고
    • Pairing of T-cell receptor chains via emulsion PCR
    • Turchaninova MA, et al. Pairing of T-cell receptor chains via emulsion PCR. Eur J Immunol 2013;43:2507-2515.
    • (2013) Eur J Immunol , vol.43 , pp. 2507-2515
    • Turchaninova, M.A.1
  • 31
    • 84887991307 scopus 로고    scopus 로고
    • Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma
    • Dudley ME, et al. Randomized selection design trial evaluating CD8+-enriched versus unselected tumor-infiltrating lymphocytes for adoptive cell therapy for patients with melanoma. J Clin Oncol 2013;31:2152-2159.
    • (2013) J Clin Oncol , vol.31 , pp. 2152-2159
    • Dudley, M.E.1
  • 32
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • Altman JD, et al. Phenotypic analysis of antigen-specific T lymphocytes. Science 1996;274:94-96.
    • (1996) Science , vol.274 , pp. 94-96
    • Altman, J.D.1
  • 33
    • 41649096341 scopus 로고    scopus 로고
    • Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7
    • Bakker AH, et al. Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. Proc Natl Acad Sci USA 2008;105:3825-3830.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3825-3830
    • Bakker, A.H.1
  • 34
    • 32244442535 scopus 로고    scopus 로고
    • Design and use of conditional MHC class I ligands
    • Toebes M, et al. Design and use of conditional MHC class I ligands. Nat Med 2006;12:246-251.
    • (2006) Nat Med , vol.12 , pp. 246-251
    • Toebes, M.1
  • 35
    • 79956158037 scopus 로고    scopus 로고
    • An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1
    • Brackenridge S, et al. An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1. J Virol 2011;85:5415-5422.
    • (2011) J Virol , vol.85 , pp. 5415-5422
    • Brackenridge, S.1
  • 36
    • 84876427574 scopus 로고    scopus 로고
    • Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases
    • Chang CX, et al. Conditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases. Eur J Immunol 2013;43:1109-1120.
    • (2013) Eur J Immunol , vol.43 , pp. 1109-1120
    • Chang, C.X.1
  • 37
    • 67649610665 scopus 로고    scopus 로고
    • Simultaneous detection of many T-cell specificities using combinatorial tetramer staining
    • Newell EW, Klein LO, Yu W, Davis MM. Simultaneous detection of many T-cell specificities using combinatorial tetramer staining. Nat Methods 2009;6:497-499.
    • (2009) Nat Methods , vol.6 , pp. 497-499
    • Newell, E.W.1    Klein, L.O.2    Yu, W.3    Davis, M.M.4
  • 38
    • 67649616555 scopus 로고    scopus 로고
    • Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers
    • Hadrup SR, et al. Parallel detection of antigen-specific T-cell responses by multidimensional encoding of MHC multimers. Nat Methods 2009;6:520-526.
    • (2009) Nat Methods , vol.6 , pp. 520-526
    • Hadrup, S.R.1
  • 39
    • 84880289310 scopus 로고    scopus 로고
    • Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization
    • Newell EW, Sigal N, Nair N, Kidd BA, Greenberg HB, Davis MM. Combinatorial tetramer staining and mass cytometry analysis facilitate T-cell epitope mapping and characterization. Nat Biotechnol 2013;31:623-629.
    • (2013) Nat Biotechnol , vol.31 , pp. 623-629
    • Newell, E.W.1    Sigal, N.2    Nair, N.3    Kidd, B.A.4    Greenberg, H.B.5    Davis, M.M.6
  • 40
    • 84886944933 scopus 로고    scopus 로고
    • TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients
    • Kvistborg P, et al. TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients. Oncoimmunology 2012;1:409-418.
    • (2012) Oncoimmunology , vol.1 , pp. 409-418
    • Kvistborg, P.1
  • 41
    • 84859399304 scopus 로고    scopus 로고
    • Dissection of T-cell antigen specificity in human melanoma
    • Andersen RS, et al. Dissection of T-cell antigen specificity in human melanoma. Cancer Res 2012;72:1642-1650.
    • (2012) Cancer Res , vol.72 , pp. 1642-1650
    • Andersen, R.S.1
  • 42
    • 84862776855 scopus 로고    scopus 로고
    • Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
    • Matsushita H, et al. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature 2012;482:400-404.
    • (2012) Nature , vol.482 , pp. 400-404
    • Matsushita, H.1
  • 43
    • 84857725402 scopus 로고    scopus 로고
    • Exploiting the mutanome for tumor vaccination
    • Castle JC, et al. Exploiting the mutanome for tumor vaccination. Cancer Res 2012;72:1081-1091.
    • (2012) Cancer Res , vol.72 , pp. 1081-1091
    • Castle, J.C.1
  • 44
    • 84880276438 scopus 로고    scopus 로고
    • Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
    • Robbins PF, et al. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nat Med 2013;19:747-752.
    • (2013) Nat Med , vol.19 , pp. 747-752
    • Robbins, P.F.1
  • 45
    • 84872841412 scopus 로고    scopus 로고
    • Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
    • van Rooij N, et al. Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma. J Clin Oncol 2013;31:e439-e442.
    • (2013) J Clin Oncol , vol.31
    • van Rooij, N.1
  • 46
    • 84879101382 scopus 로고    scopus 로고
    • Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression
    • Lu YC, et al. Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression. J Immunol 2013;190:6034-6042.
    • (2013) J Immunol , vol.190 , pp. 6034-6042
    • Lu, Y.C.1
  • 47
    • 0036498599 scopus 로고    scopus 로고
    • Identification of BING-4 cancer antigen translated from an alternative open reading frame of a gene in the extended MHC class II region using lymphocytes from a patient with a durable complete regression following immunotherapy
    • Rosenberg SA, et al. Identification of BING-4 cancer antigen translated from an alternative open reading frame of a gene in the extended MHC class II region using lymphocytes from a patient with a durable complete regression following immunotherapy. J Immunol 2002;168:2402-2407.
    • (2002) J Immunol , vol.168 , pp. 2402-2407
    • Rosenberg, S.A.1
  • 48
    • 15844363121 scopus 로고    scopus 로고
    • A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of the N-acetylglucosaminyltransferase V gene
    • Guilloux Y, et al. A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of the N-acetylglucosaminyltransferase V gene. J Exp Med 1996;183:1173-1183.
    • (1996) J Exp Med , vol.183 , pp. 1173-1183
    • Guilloux, Y.1
  • 49
    • 9144272644 scopus 로고    scopus 로고
    • A novel HLA-A*3303-restricted minor histocompatibility antigen encoded by an unconventional open reading frame of human TMSB4Y gene
    • Torikai H, et al. A novel HLA-A*3303-restricted minor histocompatibility antigen encoded by an unconventional open reading frame of human TMSB4Y gene. J Immunol 2004;173:7046-7054.
    • (2004) J Immunol , vol.173 , pp. 7046-7054
    • Torikai, H.1
  • 50
    • 52649143709 scopus 로고    scopus 로고
    • C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients
    • Tykodi SS, et al. C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients. Clin Cancer Res 2008;14:5260-5269.
    • (2008) Clin Cancer Res , vol.14 , pp. 5260-5269
    • Tykodi, S.S.1
  • 51
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013;369:134-144.
    • (2013) N Engl J Med , vol.369 , pp. 134-144
    • Hamid, O.1
  • 52
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-2454.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1
  • 53
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010;363:711-723.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1
  • 54
    • 27644534576 scopus 로고    scopus 로고
    • The response of autologous T cells to a human melanoma is dominated by mutated neoantigens
    • Lennerz V, et al. The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. Proc Natl Acad Sci USA 2005;102:16013-16018.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 16013-16018
    • Lennerz, V.1
  • 55
    • 0036284986 scopus 로고    scopus 로고
    • Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer
    • Knabel M, et al. Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer. Nat Med 2002;8:631-637.
    • (2002) Nat Med , vol.8 , pp. 631-637
    • Knabel, M.1
  • 56
    • 58149296551 scopus 로고    scopus 로고
    • Requirements for effective antitumor responses of TCR transduced T cells
    • de Witte MA, et al. Requirements for effective antitumor responses of TCR transduced T cells. J Immunol 2008;181:5128-5136.
    • (2008) J Immunol , vol.181 , pp. 5128-5136
    • de Witte, M.A.1
  • 57
    • 67349250885 scopus 로고    scopus 로고
    • Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates
    • Mates L, et al. Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates. Nat Genet 2009;41:753-761.
    • (2009) Nat Genet , vol.41 , pp. 753-761
    • Mates, L.1
  • 58
    • 69249221308 scopus 로고    scopus 로고
    • Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity
    • Peng PD, et al. Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. Gene Ther 2009;16:1042-1049.
    • (2009) Gene Ther , vol.16 , pp. 1042-1049
    • Peng, P.D.1
  • 59
    • 84873991752 scopus 로고    scopus 로고
    • Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy
    • Morgan RA, et al. Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. J Immunother 2013;36:133-151.
    • (2013) J Immunother , vol.36 , pp. 133-151
    • Morgan, R.A.1
  • 60
    • 79952187823 scopus 로고    scopus 로고
    • T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
    • Parkhurst MR, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther 2011;19:620-626.
    • (2011) Mol Ther , vol.19 , pp. 620-626
    • Parkhurst, M.R.1
  • 61
    • 44449114273 scopus 로고    scopus 로고
    • An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease
    • de Witte MA, et al. An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease. J Immunol 2008;180:6365-6373.
    • (2008) J Immunol , vol.180 , pp. 6365-6373
    • de Witte, M.A.1
  • 62
    • 38649127824 scopus 로고    scopus 로고
    • A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer
    • Kieback E, Charo J, Sommermeyer D, Blankenstein T, Uckert W. A safeguard eliminates T cell receptor gene-modified autoreactive T cells after adoptive transfer. Proc Natl Acad Sci USA 2008;105:623-628.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 623-628
    • Kieback, E.1    Charo, J.2    Sommermeyer, D.3    Blankenstein, T.4    Uckert, W.5
  • 63
    • 84883462993 scopus 로고    scopus 로고
    • MiTCR: software for T-cell receptor sequencing data analysis
    • Bolotin DA, et al. MiTCR: software for T-cell receptor sequencing data analysis. Nat Methods 2013;10:813-814.
    • (2013) Nat Methods , vol.10 , pp. 813-814
    • Bolotin, D.A.1


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