Blocking the interaction between EphB2 and ADDLs by a small peptide rescues impaired synaptic plasticity and memory deficits in a mouse model of Alzheimer’s disease

Journal of Neuroscience

Volumn 36, Issue 47, 2016, Pages 11959-11973

  Shi, Xiao Dong ^a   Sun, Kai ^a   Hu, Rui ^a   Liu, Xiao Ya ^a   Hu, Qiu Mei ^a   Sun, Xiao Yu ^a   Yao, Bin ^a   Sun, Nan ^a   Hao, Jing Ru ^a   Wei, Pan ^a   Han, Yuan ^a   Gao, Can ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer s disease; EphB2; Interfering peptides; Memory deficits; NMDA receptor trafficking; Synaptic plasticity

Indexed keywords

AMYLOID BETA PROTEIN; EPHRIN RECEPTOR B2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PEPTIDE; PRESENILIN 1; EPHB2 PROTEIN, MOUSE; LIGAND; PROTEIN BINDING;

ALZHEIMER DISEASE; AMNESIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BIOTINYLATION; CANNULATION; CONTROLLED STUDY; CROSS LINKING; EMBRYO; FEAR CONDITIONING TEST; HIPPOCAMPAL NEURONAL CULTURE; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; MALE; MORRIS WATER MAZE TEST; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; ANIMAL; DISEASE COURSE; DRUG EFFECTS; MEMORY; MEMORY DISORDERS; METABOLISM; PATHOPHYSIOLOGY; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; DISEASE PROGRESSION; LIGANDS; MALE; MEMORY; MEMORY DISORDERS; MICE; MICE, TRANSGENIC; NEURONAL PLASTICITY; PEPTIDES; PROTEIN BINDING; RECEPTOR, EPHB2; SYNAPTIC TRANSMISSION;

EID: 84997428713     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1327-16.2016     Document Type: Article

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