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Volumn 794, Issue , 2017, Pages 106-114

Berberine enhances the AMPK activation and autophagy and mitigates high glucose-induced apoptosis of mouse podocytes

Author keywords

AMPK; Autophagy; Berberine; High glucose; Podocyte

Indexed keywords

BERBERINE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; TARGET OF RAPAMYCIN KINASE;

EID: 84997285833     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2016.11.037     Document Type: Article
Times cited : (108)

References (41)
  • 1
    • 85013218853 scopus 로고    scopus 로고
    • Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway
    • Ai, F., et al. Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway. Int. J. Clin. Exp. Pathol. 8 (2015), 2509–2516.
    • (2015) Int. J. Clin. Exp. Pathol. , vol.8 , pp. 2509-2516
    • Ai, F.1
  • 2
    • 84959386672 scopus 로고    scopus 로고
    • Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro
    • Cai, X., Bao, L., Ren, J., Li, Y., Zhang, Z., Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro. Food Funct. 7 (2016), 805–815.
    • (2016) Food Funct. , vol.7 , pp. 805-815
    • Cai, X.1    Bao, L.2    Ren, J.3    Li, Y.4    Zhang, Z.5
  • 3
    • 84937710222 scopus 로고    scopus 로고
    • Berberine as a therapy for type 2 diabetes and its complications: from mechanism of action to clinical studies
    • Chang, W., Chen, L., Hatch, G.M., Berberine as a therapy for type 2 diabetes and its complications: from mechanism of action to clinical studies. Biochem. Cell Biol. 1 (2014), 1–8.
    • (2014) Biochem. Cell Biol. , vol.1 , pp. 1-8
    • Chang, W.1    Chen, L.2    Hatch, G.M.3
  • 4
    • 84938741299 scopus 로고    scopus 로고
    • Heat shock response and autophagy-cooperation and control
    • Dokladny, K., Myers, O.B., Moseley, P.L., Heat shock response and autophagy-cooperation and control. Autophagy 11 (2015), 200–213.
    • (2015) Autophagy , vol.11 , pp. 200-213
    • Dokladny, K.1    Myers, O.B.2    Moseley, P.L.3
  • 5
    • 84940896336 scopus 로고    scopus 로고
    • Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis
    • Dong, C., et al. Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis. Exp. Cell Res. 337 (2015), 146–159.
    • (2015) Exp. Cell Res. , vol.337 , pp. 146-159
    • Dong, C.1
  • 6
    • 84891689987 scopus 로고    scopus 로고
    • Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury
    • Eid, A.A., et al. Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury. Diabetes 62 (2013), 2935–2947.
    • (2013) Diabetes , vol.62 , pp. 2935-2947
    • Eid, A.A.1
  • 7
    • 84925046323 scopus 로고    scopus 로고
    • Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
    • Fan, X., et al. Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway. J. Transl. Med., 13, 2015, 92.
    • (2015) J. Transl. Med. , vol.13 , pp. 92
    • Fan, X.1
  • 8
    • 84960153111 scopus 로고    scopus 로고
    • Berberine ameliorates hepatic steatosis and suppresses liver and adipose tissue inflammation in mice with diet-induced obesity
    • Guo, T., et al. Berberine ameliorates hepatic steatosis and suppresses liver and adipose tissue inflammation in mice with diet-induced obesity. Sci. Rep., 6, 2016, 2612.
    • (2016) Sci. Rep. , vol.6 , pp. 2612
    • Guo, T.1
  • 9
    • 79951670729 scopus 로고    scopus 로고
    • Amelioration effects of berberine on diabetic microendothelial injury model by the combination of high glucose and advanced glycation end products in vitro
    • Hao, M., et al. Amelioration effects of berberine on diabetic microendothelial injury model by the combination of high glucose and advanced glycation end products in vitro. Eur. J. Pharmacol. 654 (2011), 320–325.
    • (2011) Eur. J. Pharmacol. , vol.654 , pp. 320-325
    • Hao, M.1
  • 10
    • 84893388961 scopus 로고    scopus 로고
    • mTOR signaling in autophagy regulation in the kidney
    • Inoki, K., mTOR signaling in autophagy regulation in the kidney. Semin. Nephrol. 34 (2014), 2–8.
    • (2014) Semin. Nephrol. , vol.34 , pp. 2-8
    • Inoki, K.1
  • 11
    • 84919815912 scopus 로고    scopus 로고
    • Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: role of AMPK-dependent autophagy
    • Kandadi, M.R., et al. Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: role of AMPK-dependent autophagy. Biochim. Biophys. Acta 1852 (2015), 299–309.
    • (2015) Biochim. Biophys. Acta , vol.1852 , pp. 299-309
    • Kandadi, M.R.1
  • 12
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • Kim, J., Kundu, M., Viollet, B., Guan, K.L., AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13 (2011), 132–141.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3    Guan, K.L.4
  • 13
    • 84992448510 scopus 로고    scopus 로고
    • Metformin modulates apoptosis and cell signaling of human podocytes under high glucose conditions
    • Langer, S., Kreutz, R., Eisenreich, A., Metformin modulates apoptosis and cell signaling of human podocytes under high glucose conditions. J. Nephrol. 29 (2016), 765–773.
    • (2016) J. Nephrol. , vol.29 , pp. 765-773
    • Langer, S.1    Kreutz, R.2    Eisenreich, A.3
  • 14
    • 84929224373 scopus 로고    scopus 로고
    • Tadalafil integrates nitric oxide-hydrogen sulfide signaling to inhibit high glucose-induced matrix protein synthesis in podocytes
    • Lee, H.J., et al. Tadalafil integrates nitric oxide-hydrogen sulfide signaling to inhibit high glucose-induced matrix protein synthesis in podocytes. J. Biol. Chem. 290 (2015), 12014–12026.
    • (2015) J. Biol. Chem. , vol.290 , pp. 12014-12026
    • Lee, H.J.1
  • 15
    • 84923324365 scopus 로고    scopus 로고
    • A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine
    • Lee, K.H., Lo, H.L., Tang, W.C., Hsiao, H.H., Yang, P.M., A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine. Sci. Rep., 4, 2014, 6394.
    • (2014) Sci. Rep. , vol.4 , pp. 6394
    • Lee, K.H.1    Lo, H.L.2    Tang, W.C.3    Hsiao, H.H.4    Yang, P.M.5
  • 16
    • 33749336146 scopus 로고    scopus 로고
    • Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
    • Lee, Y.S., et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 55 (2006), 2256–2264.
    • (2006) Diabetes , vol.55 , pp. 2256-2264
    • Lee, Y.S.1
  • 17
    • 84942250072 scopus 로고    scopus 로고
    • Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis
    • Lenoir, O., et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy 11 (2015), 1130–1145.
    • (2015) Autophagy , vol.11 , pp. 1130-1145
    • Lenoir, O.1
  • 19
    • 84875258906 scopus 로고    scopus 로고
    • High glucose induces autophagy in podocytes
    • Ma, T., et al. High glucose induces autophagy in podocytes. Exp. Cell Res. 319 (2013), 779–789.
    • (2013) Exp. Cell Res. , vol.319 , pp. 779-789
    • Ma, T.1
  • 20
    • 84907874514 scopus 로고    scopus 로고
    • Diabetic kidney disease: from physiology to therapeutics
    • Mora-Fernández, C., et al. Diabetic kidney disease: from physiology to therapeutics. J. Physiol. 592 (2014), 3997–4012.
    • (2014) J. Physiol. , vol.592 , pp. 3997-4012
    • Mora-Fernández, C.1
  • 21
    • 0031563832 scopus 로고    scopus 로고
    • Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cells lines
    • Mundel, P., et al. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cells lines. Exp. Cell Res. 236 (1997), 248–258.
    • (1997) Exp. Cell Res. , vol.236 , pp. 248-258
    • Mundel, P.1
  • 22
    • 84946073493 scopus 로고    scopus 로고
    • Berberine, a plant alkaloid with lipid- and glucose-lowering properties: from in vitro evidence to clinical studies
    • Pirillo, A., Catapano, A.L., Berberine, a plant alkaloid with lipid- and glucose-lowering properties: from in vitro evidence to clinical studies. Atherosclerosis 243 (2015), 449–461.
    • (2015) Atherosclerosis , vol.243 , pp. 449-461
    • Pirillo, A.1    Catapano, A.L.2
  • 24
    • 84948577375 scopus 로고    scopus 로고
    • Overview of data concerning the safe use of antihyperglycemic medications in type 2 diabetes mellitus and chronic kidney disease
    • Roussel, R., Lorraine, J., Rodriguez, A., Salaun-Martin, C., Overview of data concerning the safe use of antihyperglycemic medications in type 2 diabetes mellitus and chronic kidney disease. Adv. Ther. 32 (2015), 1029–1064.
    • (2015) Adv. Ther. , vol.32 , pp. 1029-1064
    • Roussel, R.1    Lorraine, J.2    Rodriguez, A.3    Salaun-Martin, C.4
  • 25
    • 84969897779 scopus 로고    scopus 로고
    • The histone methyltransferase enzyme enhancer of zeste homolog 2 protects against podocyte oxidative stress and renal injury in diabetes
    • Siddiqi, F.S., et al. The histone methyltransferase enzyme enhancer of zeste homolog 2 protects against podocyte oxidative stress and renal injury in diabetes. J. Am. Soc. Nephrol., 2015, 2014090898.
    • (2015) J. Am. Soc. Nephrol. , pp. 2014090898
    • Siddiqi, F.S.1
  • 26
    • 84938589035 scopus 로고    scopus 로고
    • (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose
    • Li, C., Siragy, H.M., (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am. J. Physiol. Endocrino. Metab. 309 (2015), E302–E310.
    • (2015) Am. J. Physiol. Endocrino. Metab. , vol.309 , pp. E302-E310
    • Li, C.1    Siragy, H.M.2
  • 27
    • 79952180728 scopus 로고    scopus 로고
    • The role of metabolic and haemodynamic factors in podocyte injury in diabetes
    • Stieger, N., Worthmann, K., Schiffer, M., The role of metabolic and haemodynamic factors in podocyte injury in diabetes. Diabetes Metab. Res. Rev. 27 (2011), 207–215.
    • (2011) Diabetes Metab. Res. Rev. , vol.27 , pp. 207-215
    • Stieger, N.1    Worthmann, K.2    Schiffer, M.3
  • 28
    • 84930358147 scopus 로고    scopus 로고
    • Renoprotective effect of berberine on type 2 diabetic nephropathy in rats
    • Sun, S.F., et al. Renoprotective effect of berberine on type 2 diabetic nephropathy in rats. Clin. Exp. Pharmacol. Physiol. 42 (2015), 662–670.
    • (2015) Clin. Exp. Pharmacol. Physiol. , vol.42 , pp. 662-670
    • Sun, S.F.1
  • 29
    • 84856116373 scopus 로고    scopus 로고
    • Pathophysiology of the diabetic kidney
    • Vallon, V., Komers, R., Pathophysiology of the diabetic kidney. Compr. Physiol. 1 (2011), 1175–1232.
    • (2011) Compr. Physiol. , vol.1 , pp. 1175-1232
    • Vallon, V.1    Komers, R.2
  • 30
    • 84976349724 scopus 로고    scopus 로고
    • G Protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes
    • Wang, X.X., et al. G Protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes. J. Am. Soc. Nephrol. 27 (2016), 1362–1378.
    • (2016) J. Am. Soc. Nephrol. , vol.27 , pp. 1362-1378
    • Wang, X.X.1
  • 31
    • 84955714890 scopus 로고    scopus 로고
    • Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury
    • Wei, M., Li, Z., Xiao, L., Yang, Z., Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury. Mol. Immunol. 68:2Pt A (2015), 261–271.
    • (2015) Mol. Immunol. , vol.68 , Issue.2Pt A , pp. 261-271
    • Wei, M.1    Li, Z.2    Xiao, L.3    Yang, Z.4
  • 32
    • 84995492614 scopus 로고    scopus 로고
    • Berberine attenuates development of the hepatic gluconeogenesis and lipid metabolism disorder in type 2 diabetic mice and in palmitate-incubated hepG2 cells through suppression of the HNF-4α miR122 pathway
    • Wei, S., et al. Berberine attenuates development of the hepatic gluconeogenesis and lipid metabolism disorder in type 2 diabetic mice and in palmitate-incubated hepG2 cells through suppression of the HNF-4α miR122 pathway. PLoS One, 11, 2016, e0152097.
    • (2016) PLoS One , vol.11 , pp. e0152097
    • Wei, S.1
  • 33
    • 79751496044 scopus 로고    scopus 로고
    • Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis
    • Xia, X., et al. Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis. PLoS One, 6, 2011, e16556.
    • (2011) PLoS One , vol.6 , pp. e16556
    • Xia, X.1
  • 34
    • 84997484478 scopus 로고    scopus 로고
    • HGSD attenuates neuronal apoptosis through enhancing neuronal autophagy in the brain of diabetic mice: the role of AMP-activated protein kinase
    • Xue, H., et al. HGSD attenuates neuronal apoptosis through enhancing neuronal autophagy in the brain of diabetic mice: the role of AMP-activated protein kinase. Life Sci. 3205 (2016), 30223–30225.
    • (2016) Life Sci. , vol.3205 , pp. 30223-30225
    • Xue, H.1
  • 35
    • 84893744708 scopus 로고    scopus 로고
    • The role of autophagy in the pathogenesis of diabetes nephropathy
    • Yamahara, K., et al. The role of autophagy in the pathogenesis of diabetes nephropathy. J. Diabetes Res., 2013, 193757.
    • (2013) J. Diabetes Res. , pp. 193757
    • Yamahara, K.1
  • 36
    • 84971554164 scopus 로고    scopus 로고
    • 5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetesand diabetic complications
    • Yao, F., Zhang, M., Chen, L., 5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetesand diabetic complications. Acta Pharm. Sin. B 6 (2016), 20–25.
    • (2016) Acta Pharm. Sin. B , vol.6 , pp. 20-25
    • Yao, F.1    Zhang, M.2    Chen, L.3
  • 37
    • 38349006242 scopus 로고    scopus 로고
    • Berberine improves glucose metabolism through induction of glycolysis
    • Yin, J., Gao, Z., Liu, D., Liu, Z., Ye, J., Berberine improves glucose metabolism through induction of glycolysis. Am. J. Physiol. Endocrinol. Metab. 294 (2008), E148–E156.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.294 , pp. E148-E156
    • Yin, J.1    Gao, Z.2    Liu, D.3    Liu, Z.4    Ye, J.5
  • 38
    • 84903785419 scopus 로고    scopus 로고
    • Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
    • Yu, R., et al. Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation. Cancer Cell Int., 14, 2014, 49.
    • (2014) Cancer Cell Int. , vol.14 , pp. 49
    • Yu, R.1
  • 39
    • 0037969021 scopus 로고    scopus 로고
    • Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • Zeng, X.H., Zeng, X.J., Li, Y.Y., Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am. J. Cardiol. 92 (2003), 173–176.
    • (2003) Am. J. Cardiol. , vol.92 , pp. 173-176
    • Zeng, X.H.1    Zeng, X.J.2    Li, Y.Y.3
  • 40
    • 84866917266 scopus 로고    scopus 로고
    • Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis
    • Zhang, M., et al. Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis. Mol. Cell Endocrinol. 363 (2012), 122–130.
    • (2012) Mol. Cell Endocrinol. , vol.363 , pp. 122-130
    • Zhang, M.1
  • 41
    • 84893849206 scopus 로고    scopus 로고
    • Berberine protects against palmitate-induced endothelial dysfunction: involvements of upregulation of AMPK and eNOS and downregulation of NOX4
    • Zhang, M., et al. Berberine protects against palmitate-induced endothelial dysfunction: involvements of upregulation of AMPK and eNOS and downregulation of NOX4. Mediat. Inflamm., 2013, 2013, 260464.
    • (2013) Mediat. Inflamm. , vol.2013 , pp. 260464
    • Zhang, M.1


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