-
1
-
-
85013218853
-
Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway
-
Ai, F., et al. Berberine regulates proliferation, collagen synthesis and cytokine secretion of cardiac fibroblasts via AMPK-mTOR-p70S6K signaling pathway. Int. J. Clin. Exp. Pathol. 8 (2015), 2509–2516.
-
(2015)
Int. J. Clin. Exp. Pathol.
, vol.8
, pp. 2509-2516
-
-
Ai, F.1
-
2
-
-
84959386672
-
Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro
-
Cai, X., Bao, L., Ren, J., Li, Y., Zhang, Z., Grape seed procyanidin B2 protects podocytes from high glucose-induced mitochondrial dysfunction and apoptosis via the AMPK-SIRT1-PGC-1α axis in vitro. Food Funct. 7 (2016), 805–815.
-
(2016)
Food Funct.
, vol.7
, pp. 805-815
-
-
Cai, X.1
Bao, L.2
Ren, J.3
Li, Y.4
Zhang, Z.5
-
3
-
-
84937710222
-
Berberine as a therapy for type 2 diabetes and its complications: from mechanism of action to clinical studies
-
Chang, W., Chen, L., Hatch, G.M., Berberine as a therapy for type 2 diabetes and its complications: from mechanism of action to clinical studies. Biochem. Cell Biol. 1 (2014), 1–8.
-
(2014)
Biochem. Cell Biol.
, vol.1
, pp. 1-8
-
-
Chang, W.1
Chen, L.2
Hatch, G.M.3
-
4
-
-
84938741299
-
Heat shock response and autophagy-cooperation and control
-
Dokladny, K., Myers, O.B., Moseley, P.L., Heat shock response and autophagy-cooperation and control. Autophagy 11 (2015), 200–213.
-
(2015)
Autophagy
, vol.11
, pp. 200-213
-
-
Dokladny, K.1
Myers, O.B.2
Moseley, P.L.3
-
5
-
-
84940896336
-
Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis
-
Dong, C., et al. Heme oxygenase-1 enhances autophagy in podocytes as a protective mechanism against high glucose-induced apoptosis. Exp. Cell Res. 337 (2015), 146–159.
-
(2015)
Exp. Cell Res.
, vol.337
, pp. 146-159
-
-
Dong, C.1
-
6
-
-
84891689987
-
Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury
-
Eid, A.A., et al. Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury. Diabetes 62 (2013), 2935–2947.
-
(2013)
Diabetes
, vol.62
, pp. 2935-2947
-
-
Eid, A.A.1
-
7
-
-
84925046323
-
Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway
-
Fan, X., et al. Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway. J. Transl. Med., 13, 2015, 92.
-
(2015)
J. Transl. Med.
, vol.13
, pp. 92
-
-
Fan, X.1
-
8
-
-
84960153111
-
Berberine ameliorates hepatic steatosis and suppresses liver and adipose tissue inflammation in mice with diet-induced obesity
-
Guo, T., et al. Berberine ameliorates hepatic steatosis and suppresses liver and adipose tissue inflammation in mice with diet-induced obesity. Sci. Rep., 6, 2016, 2612.
-
(2016)
Sci. Rep.
, vol.6
, pp. 2612
-
-
Guo, T.1
-
9
-
-
79951670729
-
Amelioration effects of berberine on diabetic microendothelial injury model by the combination of high glucose and advanced glycation end products in vitro
-
Hao, M., et al. Amelioration effects of berberine on diabetic microendothelial injury model by the combination of high glucose and advanced glycation end products in vitro. Eur. J. Pharmacol. 654 (2011), 320–325.
-
(2011)
Eur. J. Pharmacol.
, vol.654
, pp. 320-325
-
-
Hao, M.1
-
10
-
-
84893388961
-
mTOR signaling in autophagy regulation in the kidney
-
Inoki, K., mTOR signaling in autophagy regulation in the kidney. Semin. Nephrol. 34 (2014), 2–8.
-
(2014)
Semin. Nephrol.
, vol.34
, pp. 2-8
-
-
Inoki, K.1
-
11
-
-
84919815912
-
Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: role of AMPK-dependent autophagy
-
Kandadi, M.R., et al. Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: role of AMPK-dependent autophagy. Biochim. Biophys. Acta 1852 (2015), 299–309.
-
(2015)
Biochim. Biophys. Acta
, vol.1852
, pp. 299-309
-
-
Kandadi, M.R.1
-
12
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim, J., Kundu, M., Viollet, B., Guan, K.L., AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13 (2011), 132–141.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
13
-
-
84992448510
-
Metformin modulates apoptosis and cell signaling of human podocytes under high glucose conditions
-
Langer, S., Kreutz, R., Eisenreich, A., Metformin modulates apoptosis and cell signaling of human podocytes under high glucose conditions. J. Nephrol. 29 (2016), 765–773.
-
(2016)
J. Nephrol.
, vol.29
, pp. 765-773
-
-
Langer, S.1
Kreutz, R.2
Eisenreich, A.3
-
14
-
-
84929224373
-
Tadalafil integrates nitric oxide-hydrogen sulfide signaling to inhibit high glucose-induced matrix protein synthesis in podocytes
-
Lee, H.J., et al. Tadalafil integrates nitric oxide-hydrogen sulfide signaling to inhibit high glucose-induced matrix protein synthesis in podocytes. J. Biol. Chem. 290 (2015), 12014–12026.
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 12014-12026
-
-
Lee, H.J.1
-
15
-
-
84923324365
-
A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine
-
Lee, K.H., Lo, H.L., Tang, W.C., Hsiao, H.H., Yang, P.M., A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine. Sci. Rep., 4, 2014, 6394.
-
(2014)
Sci. Rep.
, vol.4
, pp. 6394
-
-
Lee, K.H.1
Lo, H.L.2
Tang, W.C.3
Hsiao, H.H.4
Yang, P.M.5
-
16
-
-
33749336146
-
Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states
-
Lee, Y.S., et al. Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 55 (2006), 2256–2264.
-
(2006)
Diabetes
, vol.55
, pp. 2256-2264
-
-
Lee, Y.S.1
-
17
-
-
84942250072
-
Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis
-
Lenoir, O., et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy 11 (2015), 1130–1145.
-
(2015)
Autophagy
, vol.11
, pp. 1130-1145
-
-
Lenoir, O.1
-
18
-
-
85076901763
-
Current questions and possible controversies in autophagy
-
Lindqvist, L.M., Simon, A.K., Baehrecke, E.H., Current questions and possible controversies in autophagy. Cell Death Discov., 2015, 1.
-
(2015)
Cell Death Discov.
, pp. 1
-
-
Lindqvist, L.M.1
Simon, A.K.2
Baehrecke, E.H.3
-
19
-
-
84875258906
-
High glucose induces autophagy in podocytes
-
Ma, T., et al. High glucose induces autophagy in podocytes. Exp. Cell Res. 319 (2013), 779–789.
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 779-789
-
-
Ma, T.1
-
20
-
-
84907874514
-
Diabetic kidney disease: from physiology to therapeutics
-
Mora-Fernández, C., et al. Diabetic kidney disease: from physiology to therapeutics. J. Physiol. 592 (2014), 3997–4012.
-
(2014)
J. Physiol.
, vol.592
, pp. 3997-4012
-
-
Mora-Fernández, C.1
-
21
-
-
0031563832
-
Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cells lines
-
Mundel, P., et al. Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cells lines. Exp. Cell Res. 236 (1997), 248–258.
-
(1997)
Exp. Cell Res.
, vol.236
, pp. 248-258
-
-
Mundel, P.1
-
22
-
-
84946073493
-
Berberine, a plant alkaloid with lipid- and glucose-lowering properties: from in vitro evidence to clinical studies
-
Pirillo, A., Catapano, A.L., Berberine, a plant alkaloid with lipid- and glucose-lowering properties: from in vitro evidence to clinical studies. Atherosclerosis 243 (2015), 449–461.
-
(2015)
Atherosclerosis
, vol.243
, pp. 449-461
-
-
Pirillo, A.1
Catapano, A.L.2
-
23
-
-
84902195666
-
Molecular mechanisms of diabetic kidney disease
-
Reidy, K., Kang, H.M., Hostetter, T., Susztak, K., Molecular mechanisms of diabetic kidney disease. J. Clin. Investig. 124 (2014), 2333–2340.
-
(2014)
J. Clin. Investig.
, vol.124
, pp. 2333-2340
-
-
Reidy, K.1
Kang, H.M.2
Hostetter, T.3
Susztak, K.4
-
24
-
-
84948577375
-
Overview of data concerning the safe use of antihyperglycemic medications in type 2 diabetes mellitus and chronic kidney disease
-
Roussel, R., Lorraine, J., Rodriguez, A., Salaun-Martin, C., Overview of data concerning the safe use of antihyperglycemic medications in type 2 diabetes mellitus and chronic kidney disease. Adv. Ther. 32 (2015), 1029–1064.
-
(2015)
Adv. Ther.
, vol.32
, pp. 1029-1064
-
-
Roussel, R.1
Lorraine, J.2
Rodriguez, A.3
Salaun-Martin, C.4
-
25
-
-
84969897779
-
The histone methyltransferase enzyme enhancer of zeste homolog 2 protects against podocyte oxidative stress and renal injury in diabetes
-
Siddiqi, F.S., et al. The histone methyltransferase enzyme enhancer of zeste homolog 2 protects against podocyte oxidative stress and renal injury in diabetes. J. Am. Soc. Nephrol., 2015, 2014090898.
-
(2015)
J. Am. Soc. Nephrol.
, pp. 2014090898
-
-
Siddiqi, F.S.1
-
26
-
-
84938589035
-
(Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose
-
Li, C., Siragy, H.M., (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am. J. Physiol. Endocrino. Metab. 309 (2015), E302–E310.
-
(2015)
Am. J. Physiol. Endocrino. Metab.
, vol.309
, pp. E302-E310
-
-
Li, C.1
Siragy, H.M.2
-
27
-
-
79952180728
-
The role of metabolic and haemodynamic factors in podocyte injury in diabetes
-
Stieger, N., Worthmann, K., Schiffer, M., The role of metabolic and haemodynamic factors in podocyte injury in diabetes. Diabetes Metab. Res. Rev. 27 (2011), 207–215.
-
(2011)
Diabetes Metab. Res. Rev.
, vol.27
, pp. 207-215
-
-
Stieger, N.1
Worthmann, K.2
Schiffer, M.3
-
28
-
-
84930358147
-
Renoprotective effect of berberine on type 2 diabetic nephropathy in rats
-
Sun, S.F., et al. Renoprotective effect of berberine on type 2 diabetic nephropathy in rats. Clin. Exp. Pharmacol. Physiol. 42 (2015), 662–670.
-
(2015)
Clin. Exp. Pharmacol. Physiol.
, vol.42
, pp. 662-670
-
-
Sun, S.F.1
-
29
-
-
84856116373
-
Pathophysiology of the diabetic kidney
-
Vallon, V., Komers, R., Pathophysiology of the diabetic kidney. Compr. Physiol. 1 (2011), 1175–1232.
-
(2011)
Compr. Physiol.
, vol.1
, pp. 1175-1232
-
-
Vallon, V.1
Komers, R.2
-
30
-
-
84976349724
-
G Protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes
-
Wang, X.X., et al. G Protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes. J. Am. Soc. Nephrol. 27 (2016), 1362–1378.
-
(2016)
J. Am. Soc. Nephrol.
, vol.27
, pp. 1362-1378
-
-
Wang, X.X.1
-
31
-
-
84955714890
-
Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury
-
Wei, M., Li, Z., Xiao, L., Yang, Z., Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury. Mol. Immunol. 68:2Pt A (2015), 261–271.
-
(2015)
Mol. Immunol.
, vol.68
, Issue.2Pt A
, pp. 261-271
-
-
Wei, M.1
Li, Z.2
Xiao, L.3
Yang, Z.4
-
32
-
-
84995492614
-
Berberine attenuates development of the hepatic gluconeogenesis and lipid metabolism disorder in type 2 diabetic mice and in palmitate-incubated hepG2 cells through suppression of the HNF-4α miR122 pathway
-
Wei, S., et al. Berberine attenuates development of the hepatic gluconeogenesis and lipid metabolism disorder in type 2 diabetic mice and in palmitate-incubated hepG2 cells through suppression of the HNF-4α miR122 pathway. PLoS One, 11, 2016, e0152097.
-
(2016)
PLoS One
, vol.11
, pp. e0152097
-
-
Wei, S.1
-
33
-
-
79751496044
-
Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis
-
Xia, X., et al. Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis. PLoS One, 6, 2011, e16556.
-
(2011)
PLoS One
, vol.6
, pp. e16556
-
-
Xia, X.1
-
34
-
-
84997484478
-
HGSD attenuates neuronal apoptosis through enhancing neuronal autophagy in the brain of diabetic mice: the role of AMP-activated protein kinase
-
Xue, H., et al. HGSD attenuates neuronal apoptosis through enhancing neuronal autophagy in the brain of diabetic mice: the role of AMP-activated protein kinase. Life Sci. 3205 (2016), 30223–30225.
-
(2016)
Life Sci.
, vol.3205
, pp. 30223-30225
-
-
Xue, H.1
-
35
-
-
84893744708
-
The role of autophagy in the pathogenesis of diabetes nephropathy
-
Yamahara, K., et al. The role of autophagy in the pathogenesis of diabetes nephropathy. J. Diabetes Res., 2013, 193757.
-
(2013)
J. Diabetes Res.
, pp. 193757
-
-
Yamahara, K.1
-
36
-
-
84971554164
-
5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetesand diabetic complications
-
Yao, F., Zhang, M., Chen, L., 5'-Monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetesand diabetic complications. Acta Pharm. Sin. B 6 (2016), 20–25.
-
(2016)
Acta Pharm. Sin. B
, vol.6
, pp. 20-25
-
-
Yao, F.1
Zhang, M.2
Chen, L.3
-
37
-
-
38349006242
-
Berberine improves glucose metabolism through induction of glycolysis
-
Yin, J., Gao, Z., Liu, D., Liu, Z., Ye, J., Berberine improves glucose metabolism through induction of glycolysis. Am. J. Physiol. Endocrinol. Metab. 294 (2008), E148–E156.
-
(2008)
Am. J. Physiol. Endocrinol. Metab.
, vol.294
, pp. E148-E156
-
-
Yin, J.1
Gao, Z.2
Liu, D.3
Liu, Z.4
Ye, J.5
-
38
-
-
84903785419
-
Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
-
Yu, R., et al. Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation. Cancer Cell Int., 14, 2014, 49.
-
(2014)
Cancer Cell Int.
, vol.14
, pp. 49
-
-
Yu, R.1
-
39
-
-
0037969021
-
Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
-
Zeng, X.H., Zeng, X.J., Li, Y.Y., Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am. J. Cardiol. 92 (2003), 173–176.
-
(2003)
Am. J. Cardiol.
, vol.92
, pp. 173-176
-
-
Zeng, X.H.1
Zeng, X.J.2
Li, Y.Y.3
-
40
-
-
84866917266
-
Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis
-
Zhang, M., et al. Sodium caprate augments the hypoglycemic effect of berberine via AMPK in inhibiting hepatic gluconeogenesis. Mol. Cell Endocrinol. 363 (2012), 122–130.
-
(2012)
Mol. Cell Endocrinol.
, vol.363
, pp. 122-130
-
-
Zhang, M.1
-
41
-
-
84893849206
-
Berberine protects against palmitate-induced endothelial dysfunction: involvements of upregulation of AMPK and eNOS and downregulation of NOX4
-
Zhang, M., et al. Berberine protects against palmitate-induced endothelial dysfunction: involvements of upregulation of AMPK and eNOS and downregulation of NOX4. Mediat. Inflamm., 2013, 2013, 260464.
-
(2013)
Mediat. Inflamm.
, vol.2013
, pp. 260464
-
-
Zhang, M.1
|