Efficacy and safety of berberine for congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

American Journal of Cardiology

Volumn 92, Issue 2, 2003, Pages 173-176

  Zeng, Xiang Hong ^a   Zeng, Xiang Ji ^b   Li, Yun Yun ^b  

^a Chengdu Second Municipal Hospital   (China)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BERBERINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; NITRATE; PLACEBO; SPIRONOLACTONE;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONGESTIVE CARDIOMYOPATHY; CONGESTIVE HEART FAILURE; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFICACY; DRUG SAFETY; DYSPNEA; EXERCISE; FATIGUE; FEMALE; FOLLOW UP; GASTROINTESTINAL SYMPTOM; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PROARRHYTHMIA; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE TACHYCARDIA; HOLTER MONITORING; HUMAN; ISCHEMIC HEART DISEASE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; SYMPTOM; TREATMENT OUTCOME; VOMITING; WALKING;

EID: 0037969021     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(03)00533-2     Document Type: Article

References (19)

1. Marin-Neto J.A., Maciel B.C., Secches A.L., Gallo L. Cardiovascular effects of berberine in patients with severe congestive heart failure. Clin Cardiol. 11:1988;253-260.
2. Liu J.C., Chan P., Chen Y.J., Tomlinson B., Hong S.F., Cheng J.T. The antihypertensive effect of berberine derivative 6-protoberberine in spontaneously hypertensive rats. Pharmacology. 59:1999;283-289.
3. Chun Y.T., Yip T.T., Lau K.L., Kong Y.C. A biochemical study on the hypotensive effect of berberine in rats. Gen Pharmac. 10:1978;177-182.
4. Wang Y.X., Yao X.J., Tan Y.H. Effects of berberine on delayed after-depolarizations in ventricular muscles in vitro and vivo. J Cardiovasc Pharmacol. 23:1994;716-722.
5. Zeng X.H., Li Y.Y. Clinical observations of the effect of berberine for congestive heart failure. US Chinese J Angiocardiomyopathy. 6:2001;308-311.
6. Zeng X.H., Li Y.Y., Zeng X.J. Beneficial effects of berberine in ischemic heart failure. J Qianna Medical College Nationalities. 3:2000;132-134.
7. Wong M., Bruce S., Joseph D., Lively H. Estimating left ventricular ejection fraction from two dimension echocardiograms visual and computer processed interpretations . Echocardiography. 8:1991;1-8.
8. Zeng X. HPLC determination of berberine in plasma of patients with ischemic heart failure. Chromatographia. 48:1998;589-590.
9. Feinstein A.R., Fisher M.B., Pigeon J.G. Changes in dyspnea-fatigue ratings as indicators of quality of life in the treatment of congestive heart failure. Am J Cardiol. 64:1989;50-55.
10. Thomas S., Cohn J.N. Assessment of patients' outcome with the Minnesota Living with Heart Failure questionnaire reliability and validity during a randomized, double-blind, placebo-controlled trial of pimobendan . Am Heart J. 124:1992;1017-1024.
11. Wang K.K. Mechanism of the aortic relaxation induced by low concentration of berberine. Planta Medica. 64:1998;756-757.
12. Benfey B.G. Mini review. Function of myocardial alpha-adrenoreceptors. Life Sci. 31:1982;101-106.
13. Greco R.J. Actions of new inotropic agents. The effects of berberine on vascular smooth muscle. IRCS Med Sci. 11:1983;570-575.
14. Zeng X.J., Zeng H.-X. Relationship between the clinical effects of berberine in severe congestive heart failure and its concentration in plasma studied by HPLC. Biomed Chromatogr. 13:1999;442-444.
15. Birdsall T.C., Kally G.S. Berberine. Potential of an alkaloid found in several medicinal plants. Altern Med Review. 2:1997;94. 103.
16. Ko S.T., Lim D.Y. Influence of berberine on the blood pressure of rabbits. Arch Pharmacol Res. 3:1980;23-30.
17. Chun YT, Yip TT, Lau KL, Kong YC, Sankawa U. A biochemical study on the hypotensive effect of berberine in rats. Gen Pharmacol 1979;10:177-182.
18. Sun F.L. Chinese herbs for diabetic mellitus. Chinese Prescription Drug. 7:2002;86-89.
19. Hua Z., Wang X.L. Inhibitory effect of berberine on potassium channels in guinea pig ventricular myocytes. Yao Hsueh Hsueh Pao. 29:1994;576-580.