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Volumn 27, Issue 3, 2011, Pages 207-215

The role of metabolic and haemodynamic factors in podocyte injury in diabetes

Author keywords

Apoptosis; Glucose; Nephropathy; Podocytes; Type 1 diabetes; Type 2 diabetes

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; CHEMOKINE RECEPTOR CXCR4; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYTOKINE; GLUCOSE; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GLUCOSE TRANSPORTER 4; GLUCOSE TRANSPORTER 8; OSTEOGENIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 79952180728     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.1164     Document Type: Review
Times cited : (50)

References (109)
  • 1
    • 76749103329 scopus 로고    scopus 로고
    • Diabetic kidney disease: act now or pay later
    • Atkins RC, Zimmet P. Diabetic kidney disease: act now or pay later. Kidney Int 2010; 77(5): 375-377.
    • (2010) Kidney Int , vol.77 , Issue.5 , pp. 375-377
    • Atkins, R.1    Zimmet, P.2
  • 2
    • 73949101249 scopus 로고    scopus 로고
    • Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD
    • Freedman BI, Hicks PJ, Bostrom MA, et al. Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD. Nephrol Dial Transplant 2009; 24(11): 3366-3371.
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.11 , pp. 3366-3371
    • Freedman, B.1    Hicks, P.2    Bostrom, M.3
  • 3
    • 0033772073 scopus 로고    scopus 로고
    • Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
    • Horikawa Y, Oda N, Cox NJ, et al. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet 2000; 26(2): 163-175.
    • (2000) Nat Genet , vol.26 , Issue.2 , pp. 163-175
    • Horikawa, Y.1    Oda, N.2    Cox, N.3
  • 4
    • 1842422877 scopus 로고    scopus 로고
    • A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population
    • Love-Gregory LD, Wasson J, Ma J, et al. A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population. Diabetes 2004; 53(4): 1134-1140.
    • (2004) Diabetes , vol.53 , Issue.4 , pp. 1134-1140
    • Love-Gregory, L.1    Wasson, J.2    Ma, J.3
  • 5
    • 7044229728 scopus 로고    scopus 로고
    • Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population
    • Weedon MN, Owen KR, Shields B, et al. Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population. Diabetes 2004; 53(11): 3002-3006.
    • (2004) Diabetes , vol.53 , Issue.11 , pp. 3002-3006
    • Weedon, M.1    Owen, K.2    Shields, B.3
  • 6
    • 70350774088 scopus 로고    scopus 로고
    • Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes
    • Craig DW, Millis MP, DiStefano JK. Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes. Diabet Med 2009; 26(11): 1090-1098.
    • (2009) Diabet Med , vol.26 , Issue.11 , pp. 1090-1098
    • Craig, D.1    Millis, M.2    Distefano, J.3
  • 7
    • 70149124506 scopus 로고    scopus 로고
    • Evaluation of gremlin 1 (GREM1) as a candidate susceptibility gene for albuminuria-related traits in Mexican Americans with type 2 diabetes mellitus
    • Thameem F, Puppala S, He X, et al. Evaluation of gremlin 1 (GREM1) as a candidate susceptibility gene for albuminuria-related traits in Mexican Americans with type 2 diabetes mellitus. Metabolism 2009; 58(10): 1496-1502.
    • (2009) Metabolism , vol.58 , Issue.10 , pp. 1496-1502
    • Thameem, F.1    Puppala, S.2    He, X.3
  • 8
    • 68949215691 scopus 로고    scopus 로고
    • The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans
    • McDonough CW, Hicks PJ, Lu L, et al. The influence of carnosinase gene polymorphisms on diabetic nephropathy risk in African-Americans. Hum Genet 2009; 126(2): 265-275.
    • (2009) Hum Genet , vol.126 , Issue.2 , pp. 265-275
    • Mcdonough, C.1    Hicks, P.2    Lu, L.3
  • 9
    • 12444302841 scopus 로고    scopus 로고
    • Podocytes that detach in experimental membranous nephropathy are viable
    • Petermann AT, Krofft R, Blonski M, et al. Podocytes that detach in experimental membranous nephropathy are viable. Kidney Int 2003; 64(4): 1222-1231.
    • (2003) Kidney Int , vol.64 , Issue.4 , pp. 1222-1231
    • Petermann, A.1    Krofft, R.2    Blonski, M.3
  • 10
    • 0038045430 scopus 로고    scopus 로고
    • Urinary excretion of viable podocytes in health and renal disease
    • Vogelmann SU, Nelson WJ, Myers BD, et al. Urinary excretion of viable podocytes in health and renal disease. Am J Physiol Renal Physiol 2003; 285(1): F40-F48.
    • (2003) Am J Physiol Renal Physiol , vol.285 , Issue.1
    • Vogelmann, S.1    Nelson, W.2    Myers, B.3
  • 11
    • 0034836835 scopus 로고    scopus 로고
    • Apoptosis in podocytes induced by TGF-beta and Smad7
    • Schiffer M, Bitzer M, Roberts IS, et al. Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest 2001; 108(6): 807-816.
    • (2001) J Clin Invest , vol.108 , Issue.6 , pp. 807-816
    • Schiffer, M.1    Bitzer, M.2    Roberts, I.3
  • 12
    • 0038788840 scopus 로고    scopus 로고
    • Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling
    • Huber TB, Hartleben B, Kim J, et al. Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Mol Cell Biol 2003; 23(14): 4917-4928.
    • (2003) Mol Cell Biol , vol.23 , Issue.14 , pp. 4917-4928
    • Huber, T.1    Hartleben, B.2    Kim, J.3
  • 13
    • 0035720564 scopus 로고    scopus 로고
    • Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat
    • Kim YH, Goyal M, Kurnit D, et al. Podocyte depletion and glomerulosclerosis have a direct relationship in the PAN-treated rat. Kidney Int 2001; 60(3): 957-968.
    • (2001) Kidney Int , vol.60 , Issue.3 , pp. 957-968
    • Kim, Y.1    Goyal, M.2    Kurnit, D.3
  • 14
    • 0035008793 scopus 로고    scopus 로고
    • Glomerular cell number in normal subjects and in type 1 diabetic patients
    • Steffes MW, Schmidt D, McCrery R, et al. Glomerular cell number in normal subjects and in type 1 diabetic patients. Kidney Int 2001; 59(6): 2104-2113.
    • (2001) Kidney Int , vol.59 , Issue.6 , pp. 2104-2113
    • Steffes, M.1    Schmidt, D.2    Mccrery, R.3
  • 15
    • 0036789206 scopus 로고    scopus 로고
    • Podocyte number in normotensive type 1 diabetic patients with albuminuria 25
    • White KE, Bilous RW, Marshall SM, et al. Podocyte number in normotensive type 1 diabetic patients with albuminuria 25. Diabetes 2002; 51(10): 3083-3089.
    • (2002) Diabetes , vol.51 , Issue.10 , pp. 3083-3089
    • White, K.1    Bilous, R.2    Marshall, S.3
  • 16
    • 0031029379 scopus 로고    scopus 로고
    • Podocyte loss and progressive glomerular injury in type II diabetes
    • Pagtalunan ME, Miller PL, Jumping-Eagle S, et al. Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest 1997; 99(2): 342-348.
    • (1997) J Clin Invest , vol.99 , Issue.2 , pp. 342-348
    • Pagtalunan, M.1    Miller, P.2    Jumping-Eagle, S.3
  • 17
    • 0032710966 scopus 로고    scopus 로고
    • Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria
    • Meyer TW, Bennett PH, Nelson RG. Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria. Diabetologia 1999; 42(11): 1341-1344.
    • (1999) Diabetologia , vol.42 , Issue.11 , pp. 1341-1344
    • Meyer, T.1    Bennett, P.2    Nelson, R.3
  • 18
    • 0037381607 scopus 로고    scopus 로고
    • Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes
    • Dalla VM, Masiero A, Roiter AM, et al. Is podocyte injury relevant in diabetic nephropathy? Studies in patients with type 2 diabetes. Diabetes 2003; 52(4): 1031-1035.
    • (2003) Diabetes , vol.52 , Issue.4 , pp. 1031-1035
    • Dalla, V.1    Masiero, A.2    Roiter, A.3
  • 19
    • 33644783770 scopus 로고    scopus 로고
    • Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
    • Susztak K, Raff AC, Schiffer M, et al. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 2006; 55(1): 225-233.
    • (2006) Diabetes , vol.55 , Issue.1 , pp. 225-233
    • Susztak, K.1    Raff, A.2    Schiffer, M.3
  • 20
    • 0033998369 scopus 로고    scopus 로고
    • Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes
    • Coimbra TM, Janssen U, Grone HJ, et al. Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes. Kidney Int 2000; 57(1): 167-182.
    • (2000) Kidney Int , vol.57 , Issue.1 , pp. 167-182
    • Coimbra, T.1    Janssen, U.2    Grone, H.3
  • 21
    • 35848931880 scopus 로고    scopus 로고
    • Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: role in the development of diabetic glomerular disease
    • Menini S, Iacobini C, Oddi G, et al. Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes mellitus: role in the development of diabetic glomerular disease. Diabetologia 2007; 50(12): 2591-2599.
    • (2007) Diabetologia , vol.50 , Issue.12 , pp. 2591-2599
    • Menini, S.1    Iacobini, C.2    Oddi, G.3
  • 22
    • 33645808515 scopus 로고    scopus 로고
    • Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment
    • Siu B, Saha J, Smoyer WE, et al. Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment. 2006; 7: 6.
    • (2006) , vol.7 , pp. 6
    • Siu, B.1    Saha, J.2    Smoyer, W.3
  • 23
    • 2442652562 scopus 로고    scopus 로고
    • Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy
    • Benigni A, Gagliardini E, Tomasoni S, et al. Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy. Kidney Int 2004; 65(6): 2193-2200.
    • (2004) Kidney Int , vol.65 , Issue.6 , pp. 2193-2200
    • Benigni, A.1    Gagliardini, E.2    Tomasoni, S.3
  • 24
    • 0345505674 scopus 로고    scopus 로고
    • Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II
    • Doublier S, Salvidio G, Lupia E, et al. Nephrin expression is reduced in human diabetic nephropathy: evidence for a distinct role for glycated albumin and angiotensin II. Diabetes 2003; 52(4): 1023-1030.
    • (2003) Diabetes , vol.52 , Issue.4 , pp. 1023-1030
    • Doublier, S.1    Salvidio, G.2    Lupia, E.3
  • 25
    • 33749515477 scopus 로고    scopus 로고
    • Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo
    • Menne J, Meier M, Park JK, et al. Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo. Kidney Int 2006; 70(8): 1456-1462.
    • (2006) Kidney Int , vol.70 , Issue.8 , pp. 1456-1462
    • Menne, J.1    Meier, M.2    Park, J.3
  • 26
    • 0036080664 scopus 로고    scopus 로고
    • Podocyte slit-diaphragm protein nephrin is linked to the actin cytoskeleton
    • Yuan H, Takeuchi E, Salant DJ. Podocyte slit-diaphragm protein nephrin is linked to the actin cytoskeleton. Am J Physiol Renal Physiol 2002; 282(4): F585-F591.
    • (2002) Am J Physiol Renal Physiol , vol.282 , Issue.4
    • Yuan, H.1    Takeuchi, E.2    Salant, D.3
  • 27
    • 34047099749 scopus 로고    scopus 로고
    • Nephrin is critical for the action of insulin on human glomerular podocytes
    • Coward RJ, Welsh GI, Koziell A, et al. Nephrin is critical for the action of insulin on human glomerular podocytes. Diabetes 2007; 56(4): 1127-1135.
    • (2007) Diabetes , vol.56 , Issue.4 , pp. 1127-1135
    • Coward, R.1    Welsh, G.2    Koziell, A.3
  • 28
    • 70450240920 scopus 로고    scopus 로고
    • PKC-alpha modulates TGF-beta signaling and impairs podocyte survival
    • Tossidou I, Starker G, Kruger J, et al. PKC-alpha modulates TGF-beta signaling and impairs podocyte survival. Cell Physiol Biochem 2009; 24(5-6): 627-634.
    • (2009) Cell Physiol Biochem , vol.24 , Issue.5-6 , pp. 627-634
    • Tossidou, I.1    Starker, G.2    Kruger, J.3
  • 29
    • 19944428477 scopus 로고    scopus 로고
    • Characterization of glucose uptake by cultured rat podocytes
    • Lewko B, Bryl E, Witkowski JM, et al. Characterization of glucose uptake by cultured rat podocytes. Kidney Blood Press Res 2005; 28(1): 1-7.
    • (2005) Kidney Blood Press Res , vol.28 , Issue.1 , pp. 1-7
    • Lewko, B.1    Bryl, E.2    Witkowski, J.3
  • 30
    • 41149083878 scopus 로고    scopus 로고
    • Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity
    • Pozzi A, Jarad G, Moeckel GW, et al. Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev Biol 2008; 316(2): 288-301.
    • (2008) Dev Biol , vol.316 , Issue.2 , pp. 288-301
    • Pozzi, A.1    Jarad, G.2    Moeckel, G.3
  • 31
    • 0031033557 scopus 로고    scopus 로고
    • Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus
    • Regoli M, Bendayan M. Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus. Diabetologia 1997; 40(1): 15-22.
    • (1997) Diabetologia , vol.40 , Issue.1 , pp. 15-22
    • Regoli, M.1    Bendayan, M.2
  • 32
    • 0034730249 scopus 로고    scopus 로고
    • Altering expression of alpha3beta1 integrin on podocytes of human and rats with diabetes
    • Chen HC, Chen CA, Guh JY, et al. Altering expression of alpha3beta1 integrin on podocytes of human and rats with diabetes. Life Sci 2000; 67(19): 2345-2353.
    • (2000) Life Sci , vol.67 , Issue.19 , pp. 2345-2353
    • Chen, H.1    Chen, C.2    Guh, J.3
  • 33
    • 50649092654 scopus 로고    scopus 로고
    • Astragaloside IV improves high glucose-induced podocyte adhesion dysfunction via alpha3beta1 integrin upregulation and integrin-linked kinase inhibition
    • Chen J, Gui D, Chen Y, et al. Astragaloside IV improves high glucose-induced podocyte adhesion dysfunction via alpha3beta1 integrin upregulation and integrin-linked kinase inhibition. Biochem Pharmacol 2008; 76(6): 796-804.
    • (2008) Biochem Pharmacol , vol.76 , Issue.6 , pp. 796-804
    • Chen, J.1    Gui, D.2    Chen, Y.3
  • 34
    • 0035210580 scopus 로고    scopus 로고
    • Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis
    • Kerjaschki D. Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis. J Clin Invest 2001; 108(11): 1583-1587.
    • (2001) J Clin Invest , vol.108 , Issue.11 , pp. 1583-1587
    • Kerjaschki, D.1
  • 35
    • 69249117313 scopus 로고    scopus 로고
    • Mechanical forces and TGF{beta}1 reduce podocyte adhesion through {alpha}3{beta}1 integrin downregulation
    • Dessapt C, Baradez MO, Hayward A, et al. Mechanical forces and TGF{beta}1 reduce podocyte adhesion through {alpha}3{beta}1 integrin downregulation. Nephrol Dial Transplant 2009; 24(9): 2645-2655.
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.9 , pp. 2645-2655
    • Dessapt, C.1    Baradez, M.2    Hayward, A.3
  • 36
    • 30744434618 scopus 로고    scopus 로고
    • High glucose and angiotensin II increase beta1 integrin and integrin-linked kinase synthesis in cultured mouse podocytes
    • Han SY, Kang YS, Jee YH, et al. High glucose and angiotensin II increase beta1 integrin and integrin-linked kinase synthesis in cultured mouse podocytes. Cell Tissue Res 2006; 323(2): 321-332.
    • (2006) Cell Tissue Res , vol.323 , Issue.2 , pp. 321-332
    • Han, S.1    Kang, Y.2    Jee, Y.3
  • 37
    • 0034601436 scopus 로고    scopus 로고
    • The integrin-linked kinase (ILK) suppresses anoikis
    • Attwell S, Roskelley C, Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene 2000; 19(33): 3811-3815.
    • (2000) Oncogene , vol.19 , Issue.33 , pp. 3811-3815
    • Attwell, S.1    Roskelley, C.2    Dedhar, S.3
  • 38
    • 77955172248 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria
    • Kang YS, Li Y, Dai C, et al. Inhibition of integrin-linked kinase blocks podocyte epithelial-mesenchymal transition and ameliorates proteinuria. Kidney Int 2010; 78(4): 363-373.
    • (2010) Kidney Int , vol.78 , Issue.4 , pp. 363-373
    • Kang, Y.1    Li, Y.2    Dai, C.3
  • 39
    • 33847001656 scopus 로고    scopus 로고
    • Alpha-actinin-4 is required for normal podocyte adhesion
    • Dandapani SV, Sugimoto H, Matthews BD, et al. Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem 2007; 282(1): 467-477.
    • (2007) J Biol Chem , vol.282 , Issue.1 , pp. 467-477
    • Dandapani, S.1    Sugimoto, H.2    Matthews, B.3
  • 40
    • 33749120097 scopus 로고    scopus 로고
    • High glucose and advanced glycosylated end-products affect the expression of alpha-actinin-4 in glomerular epithelial cells
    • Ha TS. High glucose and advanced glycosylated end-products affect the expression of alpha-actinin-4 in glomerular epithelial cells. Nephrology (Carlton) 2006; 11(5): 435-441.
    • (2006) Nephrology (Carlton) , vol.11 , Issue.5 , pp. 435-441
    • Ha, T.1
  • 41
    • 70350246106 scopus 로고    scopus 로고
    • Alterations of the podocyte proteome in response to high glucose concentrations
    • Schordan S, Schordan E, Endlich N, et al. Alterations of the podocyte proteome in response to high glucose concentrations. Proteomics 2009; 9(19): 4519-4528.
    • (2009) Proteomics , vol.9 , Issue.19 , pp. 4519-4528
    • Schordan, S.1    Schordan, E.2    Endlich, N.3
  • 42
    • 77955919466 scopus 로고    scopus 로고
    • Sodium-glucose transport: role in diabetes mellitus and potential clinical implications
    • Vallon V, Sharma K. Sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Curr Opin Nephrol Hypertens 2010; 19(5): 425-431.
    • (2010) Curr Opin Nephrol Hypertens , vol.19 , Issue.5 , pp. 425-431
    • Vallon, V.1    Sharma, K.2
  • 43
    • 20844450765 scopus 로고    scopus 로고
    • Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions
    • Schiffer M, Susztak K, Ranalletta M, et al. Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions. Am J Physiol Renal Physiol 2005; 289(1): F186-F193.
    • (2005) Am J Physiol Renal Physiol , vol.289 , Issue.1
    • Schiffer, M.1    Susztak, K.2    Ranalletta, M.3
  • 44
    • 77956308889 scopus 로고    scopus 로고
    • Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms
    • Csibi A, Communi D, Muller N, et al. Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms. PLoS One 2010; 5(4): e10070.
    • (2010) PLoS One , vol.5 , Issue.4
    • Csibi, A.1    Communi, D.2    Muller, N.3
  • 45
    • 68449093090 scopus 로고    scopus 로고
    • Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1
    • Lennon R, Welsh GI, Singh A, et al. Rosiglitazone enhances glucose uptake in glomerular podocytes using the glucose transporter GLUT1. Diabetologia 2009; 52(9): 1944-1952.
    • (2009) Diabetologia , vol.52 , Issue.9 , pp. 1944-1952
    • Lennon, R.1    Welsh, G.2    Singh, A.3
  • 46
    • 15344345378 scopus 로고    scopus 로고
    • Glucose transporters in diabetic nephropathy
    • Brosius FC, Heilig CW. Glucose transporters in diabetic nephropathy. Pediatr Nephrol 2005; 20(4): 447-451.
    • (2005) Pediatr Nephrol , vol.20 , Issue.4 , pp. 447-451
    • Brosius, F.1    Heilig, C.2
  • 47
    • 0030979315 scopus 로고    scopus 로고
    • D-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: implications for diabetic nephropathy
    • Heilig CW, Liu Y, England RL, et al. D-glucose stimulates mesangial cell GLUT1 expression and basal and IGF-I-sensitive glucose uptake in rat mesangial cells: implications for diabetic nephropathy. Diabetes 1997; 46(6): 1030-1039.
    • (1997) Diabetes , vol.46 , Issue.6 , pp. 1030-1039
    • Heilig, C.1    Liu, Y.2    England, R.3
  • 48
    • 77953833285 scopus 로고    scopus 로고
    • Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis
    • Wang Y, Heilig K, Saunders T, et al. Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis. Am J Physiol Renal Physiol 2010; 299(1): F99-F111.
    • (2010) Am J Physiol Renal Physiol , vol.299 , Issue.1
    • Wang, Y.1    Heilig, K.2    Saunders, T.3
  • 49
    • 77953858179 scopus 로고    scopus 로고
    • Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice
    • Zhang H, Schin M, Saha J, et al. Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice. Am J Physiol Renal Physiol 2010; 299(1): F91-F98.
    • (2010) Am J Physiol Renal Physiol , vol.299 , Issue.1
    • Zhang, H.1    Schin, M.2    Saha, J.3
  • 50
    • 33750919240 scopus 로고    scopus 로고
    • NADPH oxidases in the kidney
    • Gill PS, Wilcox CS. NADPH oxidases in the kidney. Antioxid Redox Signal 2006; 8(9-10): 1597-1607.
    • (2006) Antioxid Redox Signal , vol.8 , Issue.9-10 , pp. 1597-1607
    • Gill, P.1    Wilcox, C.2
  • 51
    • 28044455523 scopus 로고    scopus 로고
    • Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney
    • Gorin Y, Block K, Hernandez J, et al. Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. J Biol Chem 2005; 280(47): 39616-39626.
    • (2005) J Biol Chem , vol.280 , Issue.47 , pp. 39616-39626
    • Gorin, Y.1    Block, K.2    Hernandez, J.3
  • 52
    • 44449087889 scopus 로고    scopus 로고
    • Adrenomedullin protects against oxidative stress-induced podocyte injury as an endogenous antioxidant
    • Oba S, Hino M, Fujita T. Adrenomedullin protects against oxidative stress-induced podocyte injury as an endogenous antioxidant. Nephrol Dial Transplant 2008; 23(2): 510-517.
    • (2008) Nephrol Dial Transplant , vol.23 , Issue.2 , pp. 510-517
    • Oba, S.1    Hino, M.2    Fujita, T.3
  • 53
    • 70450230598 scopus 로고    scopus 로고
    • NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury
    • Wang Z, Wei X, Zhang Y, et al. NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury. Cell Physiol Biochem 2009; 24(5-6): 619-626.
    • (2009) Cell Physiol Biochem , vol.24 , Issue.5-6 , pp. 619-626
    • Wang, Z.1    Wei, X.2    Zhang, Y.3
  • 54
    • 65549157823 scopus 로고    scopus 로고
    • Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases
    • Eid AA, Gorin Y, Fagg BM, et al. Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases. Diabetes 2009; 58(5): 1201-1211.
    • (2009) Diabetes , vol.58 , Issue.5 , pp. 1201-1211
    • Eid, A.1    Gorin, Y.2    Fagg, B.3
  • 55
    • 0032999788 scopus 로고    scopus 로고
    • Poly (ADP-ribose) polymerase, nitric oxide and cell death
    • Pieper AA, Verma A, Zhang J, et al. Poly (ADP-ribose) polymerase, nitric oxide and cell death. Trends Pharmacol Sci 1999; 20(4): 171-181.
    • (1999) Trends Pharmacol Sci , vol.20 , Issue.4 , pp. 171-181
    • Pieper, A.1    Verma, A.2    Zhang, J.3
  • 56
    • 33845529318 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic Leprdb/db mice
    • Szabo C, Biser A, Benko R, et al. Poly(ADP-ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic Leprdb/db mice. Diabetes 2006; 55(11): 3004-3012.
    • (2006) Diabetes , vol.55 , Issue.11 , pp. 3004-3012
    • Szabo, C.1    Biser, A.2    Benko, R.3
  • 57
    • 31644445070 scopus 로고    scopus 로고
    • p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency
    • Wolf G, Schanze A, Stahl RA, et al. p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency. Kidney Int 2005; 68(4): 1583-1589.
    • (2005) Kidney Int , vol.68 , Issue.4 , pp. 1583-1589
    • Wolf, G.1    Schanze, A.2    Stahl, R.3
  • 58
    • 34248352591 scopus 로고    scopus 로고
    • Activation of the renin-angiotensin system within podocytes in diabetes
    • Yoo TH, Li JJ, Kim JJ, et al. Activation of the renin-angiotensin system within podocytes in diabetes. Kidney Int 2007; 71(10): 1019-1027.
    • (2007) Kidney Int , vol.71 , Issue.10 , pp. 1019-1027
    • Yoo, T.1    Li, J.2    Kim, J.3
  • 59
    • 41849096667 scopus 로고    scopus 로고
    • Angiotensin II infusion induces nephrin expression changes and podocyte apoptosis
    • Jia J, Ding G, Zhu J, et al. Angiotensin II infusion induces nephrin expression changes and podocyte apoptosis. Am J Nephrol 2008; 28(3): 500-507.
    • (2008) Am J Nephrol , vol.28 , Issue.3 , pp. 500-507
    • Jia, J.1    Ding, G.2    Zhu, J.3
  • 60
    • 77952373578 scopus 로고    scopus 로고
    • The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase
    • Godin CM, Ferguson SS. The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase. Mol Pharmacol 2010; 77(6): 903-911.
    • (2010) Mol Pharmacol , vol.77 , Issue.6 , pp. 903-911
    • Godin, C.1    Ferguson, S.2
  • 61
    • 40949137434 scopus 로고    scopus 로고
    • Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control
    • Kolavennu V, Zeng L, Peng H, et al. Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes 2008; 57(3): 714-723.
    • (2008) Diabetes , vol.57 , Issue.3 , pp. 714-723
    • Kolavennu, V.1    Zeng, L.2    Peng, H.3
  • 62
    • 60549084867 scopus 로고    scopus 로고
    • Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers
    • De Felice FG, Vieira MN, Bomfim TR, et al. Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. Proc Natl Acad Sci U S A 2009; 106(6): 1971-1976.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.6 , pp. 1971-1976
    • De Felice, F.1    Vieira, M.2    Bomfim, T.3
  • 63
    • 0141674628 scopus 로고    scopus 로고
    • Protection of myocardium by cyclosporin A and insulin: in vitro simulated ischemia study in human myocardium
    • Schneider A, Ad N, Izhar U, et al. Protection of myocardium by cyclosporin A and insulin: in vitro simulated ischemia study in human myocardium. Ann Thorac Surg 2003; 76(4): 1240-1245.
    • (2003) Ann Thorac Surg , vol.76 , Issue.4 , pp. 1240-1245
    • Schneider, A.1    Ad, N.2    Izhar, U.3
  • 64
    • 77649198940 scopus 로고    scopus 로고
    • Protective effects of continue insulin infusion on liver mitochondrion in the early stage of septic rats
    • Zeng QY, Zhang CM, Qian XH. Protective effects of continue insulin infusion on liver mitochondrion in the early stage of septic rats. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2009; 25(6): 525-528.
    • (2009) Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi , vol.25 , Issue.6 , pp. 525-528
    • Zeng, Q.1    Zhang, C.2    Qian, X.3
  • 65
    • 0018904662 scopus 로고
    • The acute effect of insulin on heart rate, blood pressure, plasma noradrenaline and urinary albumin excretion. The role of changes in blood glucose
    • Mogensen CE, Christensen NJ, Gundersen HJ. The acute effect of insulin on heart rate, blood pressure, plasma noradrenaline and urinary albumin excretion. The role of changes in blood glucose. Diabetologia 1980; 18(6): 453-457.
    • (1980) Diabetologia , vol.18 , Issue.6 , pp. 453-457
    • Mogensen, C.1    Christensen, N.2    Gundersen, H.3
  • 66
    • 73349123852 scopus 로고    scopus 로고
    • Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria
    • Jauregui A, Mintz DH, Mundel P, et al. Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria. Curr Opin Nephrol Hypertens 2009; 18(6): 539-545.
    • (2009) Curr Opin Nephrol Hypertens , vol.18 , Issue.6 , pp. 539-545
    • Jauregui, A.1    Mintz, D.2    Mundel, P.3
  • 67
    • 32244446658 scopus 로고    scopus 로고
    • The human glomerular podocyte is a novel target for insulin action
    • Coward RJ, Welsh GI, Yang J, et al. The human glomerular podocyte is a novel target for insulin action. Diabetes 2005; 54(11): 3095-3102.
    • (2005) Diabetes , vol.54 , Issue.11 , pp. 3095-3102
    • Coward, R.1    Welsh, G.2    Yang, J.3
  • 68
    • 34250013383 scopus 로고    scopus 로고
    • PPAR-gamma agonist protects podocytes from injury
    • Kanjanabuch T, Ma LJ, Chen J, et al. PPAR-gamma agonist protects podocytes from injury. Kidney Int 2007; 71(12): 1232-1239.
    • (2007) Kidney Int , vol.71 , Issue.12 , pp. 1232-1239
    • Kanjanabuch, T.1    Ma, L.2    Chen, J.3
  • 69
    • 33646686362 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis
    • Yang HC, Ma LJ, Ma J, et al. Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis. Kidney Int 2006; 69(10): 1756-1764.
    • (2006) Kidney Int , vol.69 , Issue.10 , pp. 1756-1764
    • Yang, H.1    Ma, L.2    Ma, J.3
  • 70
    • 36249006990 scopus 로고    scopus 로고
    • Rosiglitazone decreases albuminuria in type 2 diabetic patients
    • Miyazaki Y, Cersosimo E, Triplitt C, et al. Rosiglitazone decreases albuminuria in type 2 diabetic patients. Kidney Int 2007; 72(11): 1367-1373.
    • (2007) Kidney Int , vol.72 , Issue.11 , pp. 1367-1373
    • Miyazaki, Y.1    Cersosimo, E.2    Triplitt, C.3
  • 71
    • 70449707755 scopus 로고    scopus 로고
    • Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes
    • Kim MK, Ko SH, Baek KH, et al. Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes. Korean J Intern Med 2009; 24(3): 227-232.
    • (2009) Korean J Intern Med , vol.24 , Issue.3 , pp. 227-232
    • Kim, M.1    Ko, S.2    Baek, K.3
  • 72
    • 21344466513 scopus 로고    scopus 로고
    • Rosiglitazone improves glomerular hyperfiltration, renal endothelial dysfunction, and microalbuminuria of incipient diabetic nephropathy in patients
    • Pistrosch F, Herbrig K, Kindel B, et al. Rosiglitazone improves glomerular hyperfiltration, renal endothelial dysfunction, and microalbuminuria of incipient diabetic nephropathy in patients. Diabetes 2005; 54(7): 2206-2211.
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 2206-2211
    • Pistrosch, F.1    Herbrig, K.2    Kindel, B.3
  • 73
    • 43049095682 scopus 로고    scopus 로고
    • Adiponectin regulates albuminuria and podocyte function in mice
    • Sharma K, Ramachandrarao S, Qiu G, et al. Adiponectin regulates albuminuria and podocyte function in mice. J Clin Invest 2008; 118(5): 1645-1656.
    • (2008) J Clin Invest , vol.118 , Issue.5 , pp. 1645-1656
    • Sharma, K.1    Ramachandrarao, S.2    Qiu, G.3
  • 74
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002; 8(11): 1288-1295.
    • (2002) Nat Med , vol.8 , Issue.11 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3
  • 75
    • 0032792665 scopus 로고    scopus 로고
    • AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes
    • Winder WW, Hardie DG. AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes. Am J Physiol 1999; 277(1Pt1): E1-E10.
    • (1999) Am J Physiol , vol.277 , Issue.1 PART 1
    • Winder, W.1    Hardie, D.2
  • 76
    • 1842484296 scopus 로고    scopus 로고
    • AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
    • Minokoshi Y, Alquier T, Furukawa N, et al. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 2004; 428(6982): 569-574.
    • (2004) Nature , vol.428 , Issue.6982 , pp. 569-574
    • Minokoshi, Y.1    Alquier, T.2    Furukawa, N.3
  • 77
    • 73949137331 scopus 로고    scopus 로고
    • Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy
    • Lennon R, Pons D, Sabin MA, et al. Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy. Nephrol Dial Transplant 2009; 24(11): 3288-3296.
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.11 , pp. 3288-3296
    • Lennon, R.1    Pons, D.2    Sabin, M.3
  • 78
    • 19944429000 scopus 로고    scopus 로고
    • Prevention and reversal of renal injury by leptin in a new mouse model of diabetic nephropathy
    • Suganami T, Mukoyama M, Mori K, et al. Prevention and reversal of renal injury by leptin in a new mouse model of diabetic nephropathy. FASEB J 2005; 19(1): 127-129.
    • (2005) FASEB J , vol.19 , Issue.1 , pp. 127-129
    • Suganami, T.1    Mukoyama, M.2    Mori, K.3
  • 79
    • 77957229010 scopus 로고    scopus 로고
    • Insulin signaling meets mitochondria in metabolism
    • Cheng Z, Tseng Y, White MF. Insulin signaling meets mitochondria in metabolism. Trends Endocrinol Metab 2010; 21(10): 589-598.
    • (2010) Trends Endocrinol Metab , vol.21 , Issue.10 , pp. 589-598
    • Cheng, Z.1    Tseng, Y.2    White, M.3
  • 80
    • 44449119048 scopus 로고    scopus 로고
    • Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death
    • Tejada T, Catanuto P, Ijaz A, et al. Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death. Kidney Int 2008; 73(12): 1385-1393.
    • (2008) Kidney Int , vol.73 , Issue.12 , pp. 1385-1393
    • Tejada, T.1    Catanuto, P.2    Ijaz, A.3
  • 81
    • 77956340732 scopus 로고    scopus 로고
    • Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes
    • Hyvonen ME, Saurus P, Wasik A, et al. Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes. Mol Cell Endocrinol 2010; 328(1-2): 70-79.
    • (2010) Mol Cell Endocrinol , vol.328 , Issue.1-2 , pp. 70-79
    • Hyvonen, M.1    Saurus, P.2    Wasik, A.3
  • 82
    • 0035126234 scopus 로고    scopus 로고
    • Podocytes respond to mechanical stress in vitro
    • Endlich N, Kress KR, Reiser J, et al. Podocytes respond to mechanical stress in vitro. J Am Soc Nephrol 2001; 12(3): 413-422.
    • (2001) J Am Soc Nephrol , vol.12 , Issue.3 , pp. 413-422
    • Endlich, N.1    Kress, K.2    Reiser, J.3
  • 83
    • 33748864204 scopus 로고    scopus 로고
    • Podocytes are sensitive to fluid shear stress in vitro
    • Friedrich C, Endlich N, Kriz W, et al. Podocytes are sensitive to fluid shear stress in vitro. Am J Physiol Renal Physiol 2006; 291(4): F856-F865.
    • (2006) Am J Physiol Renal Physiol , vol.291 , Issue.4
    • Friedrich, C.1    Endlich, N.2    Kriz, W.3
  • 84
    • 0036149007 scopus 로고    scopus 로고
    • Mechanical stress reduces podocyte proliferation in vitro
    • Petermann AT, Hiromura K, Blonski M, et al. Mechanical stress reduces podocyte proliferation in vitro. Kidney Int 2002; 61(1): 40-50.
    • (2002) Kidney Int , vol.61 , Issue.1 , pp. 40-50
    • Petermann, A.1    Hiromura, K.2    Blonski, M.3
  • 85
    • 0037377697 scopus 로고    scopus 로고
    • RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy
    • Wendt TM, Tanji N, Guo J, et al. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy. Am J Pathol 2003; 162(4): 1123-1137.
    • (2003) Am J Pathol , vol.162 , Issue.4 , pp. 1123-1137
    • Wendt, T.1    Tanji, N.2    Guo, J.3
  • 86
    • 34948906839 scopus 로고    scopus 로고
    • Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor
    • Chuang PY, Yu Q, Fang W, et al. Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor. Kidney Int 2007; 72(8): 965-976.
    • (2007) Kidney Int , vol.72 , Issue.8 , pp. 965-976
    • Chuang, P.1    Yu, Q.2    Fang, W.3
  • 87
    • 46849090102 scopus 로고    scopus 로고
    • Advanced glycation end-products induce cell cycle arrest and hypertrophy in podocytes
    • Ruster C, Bondeva T, Franke S, et al. Advanced glycation end-products induce cell cycle arrest and hypertrophy in podocytes. Nephrol Dial Transplant 2008; 23(7): 2179-2191.
    • (2008) Nephrol Dial Transplant , vol.23 , Issue.7 , pp. 2179-2191
    • Ruster, C.1    Bondeva, T.2    Franke, S.3
  • 88
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • Puthalakath H, Huang DC, O'Reilly LA, et al. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 1999; 3(3): 287-296.
    • (1999) Mol Cell , vol.3 , Issue.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.2    O'Reilly, L.3
  • 89
    • 0036786834 scopus 로고    scopus 로고
    • TGF-beta signaling in renal disease
    • Bottinger EP, Bitzer M. TGF-beta signaling in renal disease. J Am Soc Nephrol 2002; 13(10): 2600-2610.
    • (2002) J Am Soc Nephrol , vol.13 , Issue.10 , pp. 2600-2610
    • Bottinger, E.1    Bitzer, M.2
  • 90
    • 33644877366 scopus 로고    scopus 로고
    • TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes
    • Wu DT, Bitzer M, Ju W, et al. TGF-beta concentration specifies differential signaling profiles of growth arrest/differentiation and apoptosis in podocytes. J Am Soc Nephrol 2005; 16(11): 3211-3221.
    • (2005) J Am Soc Nephrol , vol.16 , Issue.11 , pp. 3211-3221
    • Wu, D.1    Bitzer, M.2    Ju, W.3
  • 91
    • 33646918846 scopus 로고    scopus 로고
    • IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes
    • Peters I, Tossidou I, Achenbach J, et al. IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes. J Am Soc Nephrol 2006; 17(6): 1644-1656.
    • (2006) J Am Soc Nephrol , vol.17 , Issue.6 , pp. 1644-1656
    • Peters, I.1    Tossidou, I.2    Achenbach, J.3
  • 92
    • 71449099347 scopus 로고    scopus 로고
    • The balance of autocrine VEGF-A and VEGF-C determines podocyte survival
    • Mueller-Deile J, Worthmann K, Saleem MA, et al. The balance of autocrine VEGF-A and VEGF-C determines podocyte survival. Am J Physiol Renal Physiol 2009; 297(6): F1656-F1667.
    • (2009) Am J Physiol Renal Physiol , vol.297 , Issue.6
    • Mueller-Deile, J.1    Worthmann, K.2    Saleem, M.3
  • 93
    • 4344685529 scopus 로고    scopus 로고
    • A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis
    • Schiffer M, Mundel P, Shaw AS, et al. A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis. J Biol Chem 2004; 279(35): 37004-37012.
    • (2004) J Biol Chem , vol.279 , Issue.35 , pp. 37004-37012
    • Schiffer, M.1    Mundel, P.2    Shaw, A.3
  • 94
    • 40449112321 scopus 로고    scopus 로고
    • The Notch pathway in podocytes plays a role in the development of glomerular disease
    • Niranjan T, Bielesz B, Gruenwald A, et al. The Notch pathway in podocytes plays a role in the development of glomerular disease. Nat Med 2008; 14(3): 290-298.
    • (2008) Nat Med , vol.14 , Issue.3 , pp. 290-298
    • Niranjan, T.1    Bielesz, B.2    Gruenwald, A.3
  • 95
    • 0037097517 scopus 로고    scopus 로고
    • Expression of functional CCR and CXCR chemokine receptors in podocytes
    • Huber TB, Reinhardt HC, Exner M, et al. Expression of functional CCR and CXCR chemokine receptors in podocytes. J Immunol 2002; 168(12): 6244-6252.
    • (2002) J Immunol , vol.168 , Issue.12 , pp. 6244-6252
    • Huber, T.1    Reinhardt, H.2    Exner, M.3
  • 96
    • 8544275794 scopus 로고    scopus 로고
    • Podocytes are the major source of IL-1 alpha and IL-1 beta in human glomerulonephritides
    • Niemir ZI, Stein H, Dworacki G, et al. Podocytes are the major source of IL-1 alpha and IL-1 beta in human glomerulonephritides. Kidney Int 1997; 52(2): 393-403.
    • (1997) Kidney Int , vol.52 , Issue.2 , pp. 393-403
    • Niemir, Z.1    Stein, H.2    Dworacki, G.3
  • 97
    • 20144367843 scopus 로고    scopus 로고
    • Expression and regulation of adrenomedullin in renal glomerular podocytes
    • Hino M, Nagase M, Kaname S, et al. Expression and regulation of adrenomedullin in renal glomerular podocytes. Biochem Biophys Res Commun 2005; 330(1): 178-185.
    • (2005) Biochem Biophys Res Commun , vol.330 , Issue.1 , pp. 178-185
    • Hino, M.1    Nagase, M.2    Kaname, S.3
  • 98
    • 70349882090 scopus 로고    scopus 로고
    • Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes
    • Sayyed SG, Hagele H, Kulkarni OP, et al. Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes. Diabetologia 2009; 52(11): 2445-2454.
    • (2009) Diabetologia , vol.52 , Issue.11 , pp. 2445-2454
    • Sayyed, S.1    Hagele, H.2    Kulkarni, O.3
  • 99
    • 70349149467 scopus 로고    scopus 로고
    • Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes
    • Tarabra E, Giunti S, Barutta F, et al. Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. Diabetes 2009; 58(9): 2109-2118.
    • (2009) Diabetes , vol.58 , Issue.9 , pp. 2109-2118
    • Tarabra, E.1    Giunti, S.2    Barutta, F.3
  • 100
    • 59949089766 scopus 로고    scopus 로고
    • The MIF receptor CD74 in diabetic podocyte injury
    • Sanchez-Nino MD, Sanz AB, Ihalmo P, et al. The MIF receptor CD74 in diabetic podocyte injury. J Am Soc Nephrol 2009; 20(2): 353-362.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.2 , pp. 353-362
    • Sanchez-Nino, M.1    Sanz, A.2    Ihalmo, P.3
  • 101
    • 44049096503 scopus 로고    scopus 로고
    • The death ligand TRAIL in diabetic nephropathy
    • Lorz C, Benito-Martin A, Boucherot A, et al. The death ligand TRAIL in diabetic nephropathy. J Am Soc Nephrol 2008; 19(5): 904-914.
    • (2008) J Am Soc Nephrol , vol.19 , Issue.5 , pp. 904-914
    • Lorz, C.1    Benito-Martin, A.2    Boucherot, A.3
  • 102
    • 36749101547 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 delays podocyte injury due to high glucose
    • De Petris L, Hruska KA, Chiechio S, et al. Bone morphogenetic protein-7 delays podocyte injury due to high glucose. Nephrol Dial Transplant 2007; 22(12): 3442-3450.
    • (2007) Nephrol Dial Transplant , vol.22 , Issue.12 , pp. 3442-3450
    • De Petris, L.1    Hruska, K.2    Chiechio, S.3
  • 103
    • 67651149607 scopus 로고    scopus 로고
    • BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression
    • Turk T, Leeuwis JW, Gray J, et al. BMP signaling and podocyte markers are decreased in human diabetic nephropathy in association with CTGF overexpression. J Histochem Cytochem 2009; 57(7): 623-631.
    • (2009) J Histochem Cytochem , vol.57 , Issue.7 , pp. 623-631
    • Turk, T.1    Leeuwis, J.2    Gray, J.3
  • 104
    • 33748062324 scopus 로고    scopus 로고
    • Renal bone morphogenetic protein-7 protects against diabetic nephropathy
    • Wang S, de Caestecker M, Kopp J, et al. Renal bone morphogenetic protein-7 protects against diabetic nephropathy. J Am Soc Nephrol 2006; 17(9): 2504-2512.
    • (2006) J Am Soc Nephrol , vol.17 , Issue.9 , pp. 2504-2512
    • Wang, S.1    de Caestecker, M.2    Kopp, J.3
  • 105
    • 36049022526 scopus 로고    scopus 로고
    • BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury
    • Mitu GM, Wang S, Hirschberg R. BMP7 is a podocyte survival factor and rescues podocytes from diabetic injury. Am J Physiol Renal Physiol 2007; 293(5): F1641-F1648.
    • (2007) Am J Physiol Renal Physiol , vol.293 , Issue.5
    • Mitu, G.1    Wang, S.2    Hirschberg, R.3
  • 106
    • 1642379154 scopus 로고    scopus 로고
    • The role of epithelial-to-mesenchymal transition in renal fibrosis
    • Zeisberg M, Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med 2004; 82(3): 175-181.
    • (2004) J Mol Med , vol.82 , Issue.3 , pp. 175-181
    • Zeisberg, M.1    Kalluri, R.2
  • 107
    • 70349263307 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy
    • Yamaguchi Y, Iwano M, Suzuki D, et al. Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy. Am J Kidney Dis 2009; 54(4): 653-664.
    • (2009) Am J Kidney Dis , vol.54 , Issue.4 , pp. 653-664
    • Yamaguchi, Y.1    Iwano, M.2    Suzuki, D.3
  • 108
    • 59949092665 scopus 로고    scopus 로고
    • Recruitment of podocytes from glomerular parietal epithelial cells
    • Appel D, Kershaw DB, Smeets B, et al. Recruitment of podocytes from glomerular parietal epithelial cells. J Am Soc Nephrol 2009; 20(2): 333-343.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.2 , pp. 333-343
    • Appel, D.1    Kershaw, D.2    Smeets, B.3
  • 109
    • 33644503909 scopus 로고    scopus 로고
    • Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients
    • Fioretto P, Sutherland DE, Najafian B, et al. Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients. Kidney Int 2006; 69(5): 907-912.
    • (2006) Kidney Int , vol.69 , Issue.5 , pp. 907-912
    • Fioretto, P.1    Sutherland, D.2    Najafian, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.