Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: Role of AMPK-dependent autophagy

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 2, 2015, Pages 299-309

  Kandadi, Machender R ^a   Panzhinskiy, Evgeniy ^a   Roe, Nathan D ^a   Nair, Sreejayan ^a   Hu, Dahai ^b   Sun, Aijun ^a,c  

^a UNIVERSITY OF WYOMING COLLEGE OF HEALTH SCIENCES   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

Autophagy; Cardiac; Contraction; High fat diet; PTP1B

Indexed keywords

BECLIN 1; CALCIUM ION; FAT; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P62; PROTEIN TYROSINE PHOSPHATASE 1B; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR GATA 4; PTPN1 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CARDIOMYOPATHY; DIET INDUCED OBESITY; ECHOCARDIOGRAPH; ECHOCARDIOGRAPHY; FAT INTAKE; FATTY ACID METABOLISM; FEEDING; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HEART CONTRACTION; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HIGH FAT DIET INDUCED CARDIAC ANOMALY; INSULIN BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CARDIOMEGALY; COMPLICATION; DEFICIENCY; ENZYMOLOGY; FEEDING BEHAVIOR; GENE DELETION; HEART MUSCLE; HEART MUSCLE CELL; KNOCKOUT MOUSE; MALE; METABOLISM; OBESITY; PATHOLOGY; PATHOPHYSIOLOGY; WESTERN BLOTTING;

MUS; RAPTORES;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; AUTOPHAGY; BLOTTING, WESTERN; CARDIOMEGALY; DIET, HIGH-FAT; FEEDING BEHAVIOR; GENE DELETION; LIPID METABOLISM; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOCYTES, CARDIAC; OBESITY; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; TOR SERINE-THREONINE KINASES;

EID: 84919815912     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.07.004     Document Type: Article

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