메뉴 건너뛰기




Volumn 197, Issue 11, 2016, Pages 4266-4273

Suppression of IRAK1 or IRAK4 catalytic activity, but not type 1 IFN signaling, prevents lupus nephritis in mice expressing a ubiquitin binding-defective mutant of ABIN1

Author keywords

[No Author keywords available]

Indexed keywords

A20 BINDING INHIBITOR OF NUCLEAR FACTOR KAPPA B1; AUTOANTIBODY; CD135 ANTIGEN; IMMUNOGLOBULIN; INTERFERON; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MYELOID DIFFERENTIATION FACTOR 88; REGULATOR PROTEIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UBIQUITIN; UNCLASSIFIED DRUG; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK1 PROTEIN, MOUSE; IRAK4 PROTEIN, MOUSE; MEMBRANE PROTEIN; MYD88 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TLR7 PROTEIN, MOUSE; TLR9 PROTEIN, MOUSE; TNIP2 PROTEIN, MOUSE;

EID: 84996523777     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600788     Document Type: Article
Times cited : (46)

References (50)
  • 2
    • 81055141569 scopus 로고    scopus 로고
    • A20-binding inhibitor of NF-kB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein b activation and protects from inflammatory disease
    • Zhou, J., R. Wu, A. A. High, C. A. Slaughter, D. Finkelstein, J. E. Rehg, V. Redecke, and H. Häcker. 2011. A20-binding inhibitor of NF-kB (ABIN1) controls Toll-like receptor-mediated CCAAT/enhancer-binding protein b activation and protects from inflammatory disease. Proc. Natl. Acad. Sci. USA 108: E998-E1006.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. E998-E1006
    • Zhou, J.1    Wu, R.2    High, A.A.3    Slaughter, C.A.4    Finkelstein, D.5    Rehg, J.E.6    Redecke, V.7    Häcker, H.8
  • 5
    • 70350650472 scopus 로고    scopus 로고
    • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
    • Gateva, V., J. K. Sandling, G. Hom, K. E. Taylor, S. A. Chung, X. Sun, W. Ortmann, R. Kosoy, R. C. Ferreira, G. Nordmark, et al. 2009. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat. Genet. 41: 1228-1233.
    • (2009) Nat. Genet. , vol.41 , pp. 1228-1233
    • Gateva, V.1    Sandling, J.K.2    Hom, G.3    Taylor, K.E.4    Chung, S.A.5    Sun, X.6    Ortmann, W.7    Kosoy, R.8    Ferreira, R.C.9    Nordmark, G.10
  • 6
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus eryth-ematosus
    • Han, J. W., H. F. Zheng, Y. Cui, L. D. Sun, D. Q. Ye, Z. Hu, J. H. Xu, Z. M. Cai, W. Huang, G. P. Zhao, et al. 2009. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus eryth-ematosus. Nat. Genet. 41: 1234-1237.
    • (2009) Nat. Genet. , vol.41 , pp. 1234-1237
    • Han, J.W.1    Zheng, H.F.2    Cui, Y.3    Sun, L.D.4    Ye, D.Q.5    Hu, Z.6    Xu, J.H.7    Cai, Z.M.8    Huang, W.9    Zhao, G.P.10
  • 11
    • 84900454918 scopus 로고    scopus 로고
    • Association of a TNIP1 polymorphism with Vogt-Koyanagi-Harada syndrome but not with ocular Behcet's disease in Han Chinese
    • Shi, Y., Y. Jia, S. Hou, J. Fang, Y. Zhou, A. Kijlstra, and P. Yang. 2014. Association of a TNIP1 polymorphism with Vogt-Koyanagi-Harada syndrome but not with ocular Behcet's disease in Han Chinese. PLoS One 9: e95573.
    • (2014) PLoS One , vol.9 , pp. e95573
    • Shi, Y.1    Jia, Y.2    Hou, S.3    Fang, J.4    Zhou, Y.5    Kijlstra, A.6    Yang, P.7
  • 14
    • 84879467018 scopus 로고    scopus 로고
    • SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature
    • Becker, A. M., K. H. Dao, B. K. Han, R. Kornu, S. Lakhanpal, A. B. Mobley, Q. Z. Li, Y. Lian, T. Wu, A. M. Reimold, et al. 2013. SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature. PLoS One 8: e67003.
    • (2013) PLoS One , vol.8 , pp. e67003
    • Becker, A.M.1    Dao, K.H.2    Han, B.K.3    Kornu, R.4    Lakhanpal, S.5    Mobley, A.B.6    Li, Q.Z.7    Lian, Y.8    Wu, T.9    Reimold, A.M.10
  • 17
    • 0344665750 scopus 로고    scopus 로고
    • Microarray analysis of interferon-regulated genes in SLE
    • Crow, M. K., K. A. Kirou, and J. Wohlgemuth. 2003. Microarray analysis of interferon-regulated genes in SLE. Autoimmunity 36: 481-490.
    • (2003) Autoimmunity , vol.36 , pp. 481-490
    • Crow, M.K.1    Kirou, K.A.2    Wohlgemuth, J.3
  • 18
    • 80053562466 scopus 로고    scopus 로고
    • Safety profile and clinical activity of sifalimumab, a fully human anti-interferon a monoclonal antibody, in systemic lupus erythematosus: A phase I, multicentre, double-blind randomised study
    • Merrill, J. T., D. J. Wallace, M. Petri, K. A. Kirou, Y. Yao, W. I. White, G. Robbie, R. Levin, S. M. Berney, V. Chindalore, et al; Lupus Interferon Skin Activity (LISA) Study Investigators. 2011. Safety profile and clinical activity of sifalimumab, a fully human anti-interferon a monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study. Ann. Rheum. Dis. 70: 1905-1913.
    • (2011) Ann. Rheum. Dis. , vol.70 , pp. 1905-1913
    • Merrill, J.T.1    Wallace, D.J.2    Petri, M.3    Kirou, K.A.4    Yao, Y.5    White, W.I.6    Robbie, G.7    Levin, R.8    Berney, S.M.9    Chindalore, V.10
  • 19
    • 0035823645 scopus 로고    scopus 로고
    • Characterization and humanization of a monoclonal anti-body that neutralizes human leukocyte interferon: A candidate therapeutic for IDDM and SLE
    • Chuntharapai, A., J. Lai, X. Huang, V. Gibbs, K. J. Kim, L. G. Presta, and T. A. Stewart. 2001. Characterization and humanization of a monoclonal anti-body that neutralizes human leukocyte interferon: a candidate therapeutic for IDDM and SLE. Cytokine 15: 250-260.
    • (2001) Cytokine , vol.15 , pp. 250-260
    • Chuntharapai, A.1    Lai, J.2    Huang, X.3    Gibbs, V.4    Kim, K.J.5    Presta, L.G.6    Stewart, T.A.7
  • 21
    • 77953714711 scopus 로고    scopus 로고
    • Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
    • Lin, S. C., Y. C. Lo, and H. Wu. 2010. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 465: 885-890.
    • (2010) Nature , vol.465 , pp. 885-890
    • Lin, S.C.1    Lo, Y.C.2    Wu, H.3
  • 23
    • 84904128358 scopus 로고    scopus 로고
    • An un-expected twist to the activation of IKKb: TAK1 primes IKKb for activation by autophosphorylation
    • Zhang, J., K. Clark, T. Lawrence, M. W. Peggie, and P. Cohen. 2014. An un-expected twist to the activation of IKKb: TAK1 primes IKKb for activation by autophosphorylation. Biochem. J. 461: 531-537.
    • (2014) Biochem. J. , vol.461 , pp. 531-537
    • Zhang, J.1    Clark, K.2    Lawrence, T.3    Peggie, M.W.4    Cohen, P.5
  • 24
    • 84886442156 scopus 로고    scopus 로고
    • Molecular control of the NEMO family of ubiquitin-binding proteins
    • Clark, K., S. Nanda, and P. Cohen. 2013. Molecular control of the NEMO family of ubiquitin-binding proteins. Nat. Rev. Mol. Cell Biol. 14: 673-685.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 673-685
    • Clark, K.1    Nanda, S.2    Cohen, P.3
  • 25
    • 84916217073 scopus 로고    scopus 로고
    • Protein kinase IKKb-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells
    • Lopez-Pelaez, M., D. J. Lamont, M. Peggie, N. Shpiro, N. S. Gray, and P. Cohen. 2014. Protein kinase IKKb-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells. Proc. Natl. Acad. Sci. USA 111: 17432-17437.
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 17432-17437
    • Lopez-Pelaez, M.1    Lamont, D.J.2    Peggie, M.3    Shpiro, N.4    Gray, N.S.5    Cohen, P.6
  • 26
    • 84916201016 scopus 로고    scopus 로고
    • IKKb is an IRF5 kinase that instigates inflammation
    • Ren, J., X. Chen, and Z. J. Chen. 2014. IKKb is an IRF5 kinase that instigates inflammation. Proc. Natl. Acad. Sci. USA 111: 17438-17443.
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 17438-17443
    • Ren, J.1    Chen, X.2    Chen, Z.J.3
  • 27
    • 84055219427 scopus 로고    scopus 로고
    • Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system
    • Goh, E. T., J. S. Arthur, P. C. Cheung, S. Akira, R. Toth, and P. Cohen. 2012. Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system. Biochem. J. 441: 339-346.
    • (2012) Biochem. J. , vol.441 , pp. 339-346
    • Goh, E.T.1    Arthur, J.S.2    Cheung, P.C.3    Akira, S.4    Toth, R.5    Cohen, P.6
  • 28
    • 84883406297 scopus 로고    scopus 로고
    • Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice
    • Pauls, E., S. K. Nanda, H. Smith, R. Toth, J. S. Arthur, and P. Cohen. 2013. Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice. J. Immunol. 191: 2717-2730.
    • (2013) J. Immunol. , vol.191 , pp. 2717-2730
    • Pauls, E.1    Nanda, S.K.2    Smith, H.3    Toth, R.4    Arthur, J.S.5    Cohen, P.6
  • 29
    • 84971201127 scopus 로고    scopus 로고
    • Striking immune phenotypes in gene-targeted mice are driven by a copy-number variant originating from a commercially available C57BL/6 strain
    • Mahajan, V. S., E. Demissie, H. Mattoo, V. Viswanadham, A. Varki, R. Morris, and S. Pillai. 2016. Striking immune phenotypes in gene-targeted mice are driven by a copy-number variant originating from a commercially available C57BL/6 strain. Cell Rep. 15: 1901-1909.
    • (2016) Cell Rep. , vol.15 , pp. 1901-1909
    • Mahajan, V.S.1    Demissie, E.2    Mattoo, H.3    Viswanadham, V.4    Varki, A.5    Morris, R.6    Pillai, S.7
  • 30
    • 84890098871 scopus 로고    scopus 로고
    • Influenza A virus impairs control of Mycobac-terium tuberculosis coinfection through a type i interferon receptor-dependent pathway
    • Redford, P. S., K. D. Mayer-Barber, F. W. McNab, E. Stavropoulos, A. Wack, A. Sher, and A. O'Garra. 2014. Influenza A virus impairs control of Mycobac-terium tuberculosis coinfection through a type I interferon receptor-dependent pathway. J. Infect. Dis. 209: 270-274.
    • (2014) J. Infect. Dis. , vol.209 , pp. 270-274
    • Redford, P.S.1    Mayer-Barber, K.D.2    McNab, F.W.3    Stavropoulos, E.4    Wack, A.5    Sher, A.6    O'Garra, A.7
  • 31
    • 84898655870 scopus 로고    scopus 로고
    • Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner
    • Cushing, L., W. Stochaj, M. Siegel, R. Czerwinski, K. Dower, Q. Wright, M. Hirschfield, J. L. Casanova, C. Picard, A. Puel, et al. 2014. Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner. J. Biol. Chem. 289: 10865-10875.
    • (2014) J. Biol. Chem. , vol.289 , pp. 10865-10875
    • Cushing, L.1    Stochaj, W.2    Siegel, M.3    Czerwinski, R.4    Dower, K.5    Wright, Q.6    Hirschfield, M.7    Casanova, J.L.8    Picard, C.9    Puel, A.10
  • 32
    • 84887527334 scopus 로고    scopus 로고
    • Principles for valid histopathologic scoring in research
    • Gibson-Corley, K. N., A. K. Olivier, and D. K. Meyerholz. 2013. Principles for valid histopathologic scoring in research. Vet. Pathol. 50: 1007-1015.
    • (2013) Vet. Pathol. , vol.50 , pp. 1007-1015
    • Gibson-Corley, K.N.1    Olivier, A.K.2    Meyerholz, D.K.3
  • 33
    • 84861728909 scopus 로고    scopus 로고
    • Essential role for IKKb in production of type 1 interferons by plasmacytoid dendritic cells
    • Pauls, E., N. Shpiro, M. Peggie, E. R. Young, R. J. Sorcek, L. Tan, H. G. Choi, and P. Cohen. 2012. Essential role for IKKb in production of type 1 interferons by plasmacytoid dendritic cells. J. Biol. Chem. 287: 19216-19228.
    • (2012) J. Biol. Chem. , vol.287 , pp. 19216-19228
    • Pauls, E.1    Shpiro, N.2    Peggie, M.3    Young, E.R.4    Sorcek, R.J.5    Tan, L.6    Choi, H.G.7    Cohen, P.8
  • 35
    • 0026342401 scopus 로고
    • Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
    • Knighton, D. R., J. H. Zheng, L. F. Ten Eyck, V. A. Ashford, N. H. Xuong, S. S. Taylor, and J. M. Sowadski. 1991. Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science 253: 407-414.
    • (1991) Science , vol.253 , pp. 407-414
    • Knighton, D.R.1    Zheng, J.H.2    Ten Eyck, L.F.3    Ashford, V.A.4    Xuong, N.H.5    Taylor, S.S.6    Sowadski, J.M.7
  • 37
    • 34249095729 scopus 로고    scopus 로고
    • Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling
    • Kawagoe, T., S. Sato, A. Jung, M. Yamamoto, K. Matsui, H. Kato, S. Uematsu, O. Takeuchi, and S. Akira. 2007. Essential role of IRAK-4 protein and its kinase activity in Toll-like receptor-mediated immune responses but not in TCR signaling. J. Exp. Med. 204: 1013-1024.
    • (2007) J. Exp. Med. , vol.204 , pp. 1013-1024
    • Kawagoe, T.1    Sato, S.2    Jung, A.3    Yamamoto, M.4    Matsui, K.5    Kato, H.6    Uematsu, S.7    Takeuchi, O.8    Akira, S.9
  • 38
    • 75749083254 scopus 로고    scopus 로고
    • Deficiency of type i IFN receptor in lupus-prone New Zealand mixed 2328 mice decreases dendritic cell numbers and activation and protects from disease
    • Agrawal, H., N. Jacob, E. Carreras, S. Bajana, C. Putterman, S. Turner, B. Neas, A. Mathian, M. N. Koss, W. Stohl, et al. 2009. Deficiency of type I IFN receptor in lupus-prone New Zealand mixed 2328 mice decreases dendritic cell numbers and activation and protects from disease. J. Immunol. 183: 6021-6029.
    • (2009) J. Immunol. , vol.183 , pp. 6021-6029
    • Agrawal, H.1    Jacob, N.2    Carreras, E.3    Bajana, S.4    Putterman, C.5    Turner, S.6    Neas, B.7    Mathian, A.8    Koss, M.N.9    Stohl, W.10
  • 40
    • 0027930909 scopus 로고
    • Interleukin 6 promotes murine lupus in NZB/NZW F1 mice
    • Finck, B. K., B. Chan, and D. Wofsy. 1994. Interleukin 6 promotes murine lupus in NZB/NZW F1 mice. J. Clin. Invest. 94: 585-591.
    • (1994) J. Clin. Invest. , vol.94 , pp. 585-591
    • Finck, B.K.1    Chan, B.2    Wofsy, D.3
  • 41
    • 0031861643 scopus 로고    scopus 로고
    • IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice
    • Mihara, M., N. Takagi, Y. Takeda, and Y. Ohsugi. 1998. IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice. Clin. Exp. Immunol. 112: 397-402.
    • (1998) Clin. Exp. Immunol. , vol.112 , pp. 397-402
    • Mihara, M.1    Takagi, N.2    Takeda, Y.3    Ohsugi, Y.4
  • 42
    • 80054774247 scopus 로고    scopus 로고
    • The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling
    • Clark, K., O. Takeuchi, S. Akira, and P. Cohen. 2011. The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling. Proc. Natl. Acad. Sci. USA 108: 17093-17098.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 17093-17098
    • Clark, K.1    Takeuchi, O.2    Akira, S.3    Cohen, P.4
  • 43
    • 69049086481 scopus 로고    scopus 로고
    • TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
    • Kawagoe, T., O. Takeuchi, Y. Takabatake, H. Kato, Y. Isaka, T. Tsujimura, and S. Akira. 2009. TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat. Immunol. 10: 965-972.
    • (2009) Nat. Immunol. , vol.10 , pp. 965-972
    • Kawagoe, T.1    Takeuchi, O.2    Takabatake, Y.3    Kato, H.4    Isaka, Y.5    Tsujimura, T.6    Akira, S.7
  • 44
    • 84962128086 scopus 로고    scopus 로고
    • Personalized immu-nomonitoring uncovers molecular networks that stratify lupus patients. [Published erratum appears in 2016 Cell 165: 1548-1550]
    • Banchereau, R., S. Hong, B. Cantarel, N. Baldwin, J. Baisch, M. Edens, A. M. Cepika, P. Acs, J. Turner, E. Anguiano, et al. 2016. Personalized immu-nomonitoring uncovers molecular networks that stratify lupus patients. [Published erratum appears in 2016 Cell 165: 1548-1550] Cell 165: 551-565.
    • (2016) Cell , vol.165 , pp. 551-565
    • Banchereau, R.1    Hong, S.2    Cantarel, B.3    Baldwin, N.4    Baisch, J.5    Edens, M.6    Cepika, A.M.7    Acs, P.8    Turner, J.9    Anguiano, E.10
  • 46
    • 84878190840 scopus 로고    scopus 로고
    • Immune sensing of DNA
    • Paludan, S. R., and A. G. Bowie. 2013. Immune sensing of DNA. Immunity 38: 870-880.
    • (2013) Immunity , vol.38 , pp. 870-880
    • Paludan, S.R.1    Bowie, A.G.2
  • 47
    • 79960121968 scopus 로고    scopus 로고
    • Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IkBa deficiency
    • Picard, C., J. L. Casanova, and A. Puel. 2011. Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IkBa deficiency. Clin. Microbiol. Rev. 24: 490-497.
    • (2011) Clin. Microbiol. Rev. , vol.24 , pp. 490-497
    • Picard, C.1    Casanova, J.L.2    Puel, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.