Fumarate modulates the immune/inflammatory response and rescues nerve cells and neurological function after stroke in rats

Journal of Neuroinflammation

Volumn 13, Issue 1, 2016, Pages

  Lin, Ruihe ^a   Cai, Jingli ^a   Kostuk, Eric W ^a   Rosenwasser, Robert ^a   Iacovitti, Lorraine ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Dimethyl fumarate; Inflammation; Stroke

Indexed keywords

FUMARIC ACID; LACTATE DEHYDROGENASE; AUTACOID; FUMARIC ACID DIMETHYL ESTER;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BEHAVIOR DISORDER; BRAIN INFARCTION SIZE; CELL ACTIVATION; CELL COUNTING; CELL INFILTRATION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; IMMUNOMODULATION ACTIVITY; IN VITRO STUDY; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL CULTURE; NERVE CELL RESCUE; NERVOUS SYSTEM FUNCTION; NERVOUS SYSTEM PARAMETERS; NEUTROPHIL; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; RAT; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELLULAR IMMUNITY; CONVALESCENCE; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STROKE;

ANIMALS; CELLS, CULTURED; DIMETHYL FUMARATE; IMMUNITY, CELLULAR; INFLAMMATION MEDIATORS; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; STROKE;

EID: 84994884880     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-016-0733-1     Document Type: Article

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