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Volumn 311, Issue 5, 2016, Pages F831-F843

Rethinking glomerular basement membrane thickening in diabetic nephropathy: Adaptive or pathogenic?

Author keywords

Glomerular filtration barrier; Podocyte; Podocyte glomerular basement membrane interface

Indexed keywords

COLLAGEN TYPE 17; DYSTROGLYCAN; INTEGRIN; LAMININ; MATRIX METALLOPROTEINASE; PROTEOGLYCAN; PROTEOHEPARAN SULFATE; SYNDECAN 1; SYNDECAN 4; TETRASPANIN; VERY LATE ACTIVATION ANTIGEN 3;

EID: 84994662886     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00313.2016     Document Type: Review
Times cited : (95)

References (198)
  • 1
    • 65949118275 scopus 로고    scopus 로고
    • Development of kidney glomerular endothelial cells and their role in basement membrane assembly
    • Abrahamson DR. Development of kidney glomerular endothelial cells and their role in basement membrane assembly. Organogenesis 5: 275-287, 2009.
    • (2009) Organogenesis , vol.5 , pp. 275-287
    • Abrahamson, D.R.1
  • 2
    • 0025826207 scopus 로고
    • Glomerulogenesis in the developing kidney
    • Abrahamson DR. Glomerulogenesis in the developing kidney. Semin Nephrol 11: 375-389, 1991.
    • (1991) Semin Nephrol , vol.11 , pp. 375-389
    • Abrahamson, D.R.1
  • 3
    • 84865707513 scopus 로고    scopus 로고
    • Role of the podocyte (and glomerular endothelium) in building the GBM
    • Abrahamson DR. Role of the podocyte (and glomerular endothelium) in building the GBM. Semin Nephrol 32: 342-349, 2012.
    • (2012) Semin Nephrol , vol.32 , pp. 342-349
    • Abrahamson, D.R.1
  • 4
  • 5
    • 0037213037 scopus 로고    scopus 로고
    • Development and progression of nephropathy in type 2 diabetes: The United Kingdom Prospective Diabetes Study (UKPDS 64)
    • Adler AI, Stevens RJ, Manley SE, Bilous RW, Cull CA, Holman RR, Ukpds G. Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64). Kidney Int 63: 225-232, 2003.
    • (2003) Kidney Int , vol.63 , pp. 225-232
    • Adler, A.I.1    Stevens, R.J.2    Manley, S.E.3    Bilous, R.W.4    Cull, C.A.5    Holman, R.R.6    Ukpds, G.7
  • 6
    • 0026757674 scopus 로고
    • Characterization of glomerular epithelial cell matrix receptors
    • Adler S. Characterization of glomerular epithelial cell matrix receptors. Am J Pathol 141: 571-578, 1992.
    • (1992) Am J Pathol , vol.141 , pp. 571-578
    • Adler, S.1
  • 7
    • 0028545769 scopus 로고
    • Structure-function relationships associated with extracellular matrix alterations in diabetic glomerulopathy
    • Adler S. Structure-function relationships associated with extracellular matrix alterations in diabetic glomerulopathy. J Am Soc Nephrol 5:1165-1172, 1994.
    • (1994) J Am Soc Nephrol , vol.5 , pp. 1165-1172
    • Adler, S.1
  • 8
    • 0029823195 scopus 로고    scopus 로고
    • A steady-state labelling approach to the measurement of proteoglycan turnover in vivo and its application to glomerular proteoglycans
    • Akuffo EL, Hunt JR, Moss J, Woodrow D, Davies M, Mason RM. A steady-state labelling approach to the measurement of proteoglycan turnover in vivo and its application to glomerular proteoglycans. Biochem J 320: 301-308, 1996.
    • (1996) Biochem J , vol.320 , pp. 301-308
    • Akuffo, E.L.1    Hunt, J.R.2    Moss, J.3    Woodrow, D.4    Davies, M.5    Mason, R.M.6
  • 9
    • 84987837603 scopus 로고    scopus 로고
    • Molecular and cellular events mediating glomerular podocyte dysfunction and depletion in diabetes mellitus
    • Anil Kumar P, Welsh GI, Saleem MA, Menon RK. Molecular and cellular events mediating glomerular podocyte dysfunction and depletion in diabetes mellitus. Front Endocrinol (Lausanne) 5:151, 2014.
    • (2014) Front Endocrinol (Lausanne) , vol.5 , pp. 151
    • Anil Kumar, P.1    Welsh, G.I.2    Saleem, M.A.3    Menon, R.K.4
  • 10
    • 33750212860 scopus 로고    scopus 로고
    • Molecular basis of inherited skin-blistering disorders, and therapeutic implications
    • Aumailley M, Has C, Tunggal L, Bruckner-Tuderman L. Molecular basis of inherited skin-blistering disorders, and therapeutic implications. Expert Rev Mol Med 8: 1-21, 2006.
    • (2006) Expert Rev Mol Med , vol.8 , pp. 1-21
    • Aumailley, M.1    Has, C.2    Tunggal, L.3    Bruckner-Tuderman, L.4
  • 12
    • 33644995630 scopus 로고    scopus 로고
    • High ambient glucose levels modulates the production of MMP-9 and alpha5(IV) collagen by cultured podocytes
    • Bai Y, Wang L, Li Y, Liu S, Li J, Wang H, Huang H. High ambient glucose levels modulates the production of MMP-9 and alpha5(IV) collagen by cultured podocytes. Cell Physiol Biochem 17: 57-68, 2006.
    • (2006) Cell Physiol Biochem , vol.17 , pp. 57-68
    • Bai, Y.1    Wang, L.2    Li, Y.3    Liu, S.4    Li, J.5    Wang, H.6    Huang, H.7
  • 13
    • 53149111544 scopus 로고    scopus 로고
    • Deletion of CD151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane
    • Baleato RM, Guthrie PL, Gubler MC, Ashman LK, Roselli S. Deletion of CD151 results in a strain-dependent glomerular disease due to severe alterations of the glomerular basement membrane. Am J Pathol 173: 927-937, 2008.
    • (2008) Am J Pathol , vol.173 , pp. 927-937
    • Baleato, R.M.1    Guthrie, P.L.2    Gubler, M.C.3    Ashman, L.K.4    Roselli, S.5
  • 14
    • 0026476115 scopus 로고
    • Very late activation-3 integrin is the dominant beta 1-integrin on the glomerular capillary wall: An immunofluorescence study in nephrotic syndrome
    • Baraldi A, Furci L, Zambruno G, Rubbiani E, Annessi G, Lusvarghi E. Very late activation-3 integrin is the dominant beta 1-integrin on the glomerular capillary wall: an immunofluorescence study in nephrotic syndrome. Nephron 62: 382-388, 1992.
    • (1992) Nephron , vol.62 , pp. 382-388
    • Baraldi, A.1    Furci, L.2    Zambruno, G.3    Rubbiani, E.4    Annessi, G.5    Lusvarghi, E.6
  • 15
    • 0027976552 scopus 로고
    • Beta-1 integrins in the normal human glomerular capillary wall: An immunoelectron microscopy study
    • Baraldi A, Zambruno G, Furci L, Manca V, Vaschieri C, Lusvarghi E. Beta-1 integrins in the normal human glomerular capillary wall: an immunoelectron microscopy study. Nephron 66: 295-301, 1994.
    • (1994) Nephron , vol.66 , pp. 295-301
    • Baraldi, A.1    Zambruno, G.2    Furci, L.3    Manca, V.4    Vaschieri, C.5    Lusvarghi, E.6
  • 17
    • 0024503512 scopus 로고
    • In vivo turnover of the basement membrane and other heparan sulfate proteoglycans of rat glomerulus
    • Beavan LA, Davies M, Couchman JR, Williams MA, Mason RM. In vivo turnover of the basement membrane and other heparan sulfate proteoglycans of rat glomerulus. Arch Biochem Biophys 269: 576-585, 1989.
    • (1989) Arch Biochem Biophys , vol.269 , pp. 576-585
    • Beavan, L.A.1    Davies, M.2    Couchman, J.R.3    Williams, M.A.4    Mason, R.M.5
  • 18
    • 0021876578 scopus 로고
    • Alteration in the distribution of type IV collagen in glomerular basal laminae in diabetic rats as revealed by immunocytochemistry and morphometrical approach
    • Bendayan M. Alteration in the distribution of type IV collagen in glomerular basal laminae in diabetic rats as revealed by immunocytochemistry and morphometrical approach. Diabetologia 28: 373-378, 1985.
    • (1985) Diabetologia , vol.28 , pp. 373-378
    • Bendayan, M.1
  • 19
    • 0035207920 scopus 로고    scopus 로고
    • Complexes of tetraspanins with integrins: More than meets the eye
    • Berditchevski F. Complexes of tetraspanins with integrins: more than meets the eye. J Cell Sci 114: 4143-4151, 2001.
    • (2001) J Cell Sci , vol.114 , pp. 4143-4151
    • Berditchevski, F.1
  • 20
    • 0023094924 scopus 로고
    • Polycation binding to glomerular basement membrane. Effect of biochemical modification
    • Bertolatus JA, Hunsicker LG. Polycation binding to glomerular basement membrane. Effect of biochemical modification. Lab Invest 56:170-179, 1987.
    • (1987) Lab Invest , vol.56 , pp. 170-179
    • Bertolatus, J.A.1    Hunsicker, L.G.2
  • 23
    • 0020132520 scopus 로고
    • 35S-glycosaminoglycan and 35S-glycopeptide metabolism by diabetic glomeruli and aorta
    • Brown DM, Klein DJ, Michael AF, Oegema TR. 35S-glycosaminoglycan and 35S-glycopeptide metabolism by diabetic glomeruli and aorta. Diabetes 31: 418-425, 1982.
    • (1982) Diabetes , vol.31 , pp. 418-425
    • Brown, D.M.1    Klein, D.J.2    Michael, A.F.3    Oegema, T.R.4
  • 24
    • 0018342568 scopus 로고
    • Glomerular basement membrane metabolism in the diabetic rat. In vivo studies
    • Brownlee M, Spiro RG. Glomerular basement membrane metabolism in the diabetic rat. In vivo studies. Diabetes 28: 121-125, 1979.
    • (1979) Diabetes , vol.28 , pp. 121-125
    • Brownlee, M.1    Spiro, R.G.2
  • 26
    • 0345505677 scopus 로고    scopus 로고
    • Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients: An indicator of more advanced glomerular lesions
    • Caramori ML, Fioretto P, Mauer M. Low glomerular filtration rate in normoalbuminuric type 1 diabetic patients: an indicator of more advanced glomerular lesions. Diabetes 52: 1036-1040, 2003.
    • (2003) Diabetes , vol.52 , pp. 1036-1040
    • Caramori, M.L.1    Fioretto, P.2    Mauer, M.3
  • 27
    • 0036068369 scopus 로고    scopus 로고
    • Cellular basis of diabetic nephropathy. 1. Study design and renal structural-functional relationships in patients with longstanding type 1 diabetes
    • Caramori ML, Kim Y, Huang C, Fish AJ, Rich SS, Miller ME, Russell G, Mauer M. Cellular basis of diabetic nephropathy. 1. Study design and renal structural-functional relationships in patients with longstanding type 1 diabetes. Diabetes 51: 506-513, 2002.
    • (2002) Diabetes , vol.51 , pp. 506-513
    • Caramori, M.L.1    Kim, Y.2    Huang, C.3    Fish, A.J.4    Rich, S.S.5    Miller, M.E.6    Russell, G.7    Mauer, M.8
  • 28
    • 84879979804 scopus 로고    scopus 로고
    • Renal lesions predict progression of diabetic nephropathy in type 1 diabetes
    • Caramori ML, Parks A, Mauer M. Renal lesions predict progression of diabetic nephropathy in type 1 diabetes. J Am Soc Nephrol 24: 1175-1181, 2013.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1175-1181
    • Caramori, M.L.1    Parks, A.2    Mauer, M.3
  • 29
    • 33847788654 scopus 로고    scopus 로고
    • Role of matrix metalloproteinases in renal pathophysiologies
    • Catania JM, Chen G, Parrish AR. Role of matrix metalloproteinases in renal pathophysiologies. Am J Physiol Renal Physiol 292:F905-F911, 2007.
    • (2007) Am J Physiol Renal Physiol , vol.292 , pp. F905-F911
    • Catania, J.M.1    Chen, G.2    Parrish, A.R.3
  • 30
    • 38349151637 scopus 로고    scopus 로고
    • Unilateral nephrectomy leads to up-regulation of syndecan-2- and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice
    • Cevikbas F, Schaefer L, Uhlig P, Robenek H, Theilmeier G, Echtermeyer F, Bruckner P. Unilateral nephrectomy leads to up-regulation of syndecan-2- and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice. Matrix Biol 27: 42-52, 2008.
    • (2008) Matrix Biol , vol.27 , pp. 42-52
    • Cevikbas, F.1    Schaefer, L.2    Uhlig, P.3    Robenek, H.4    Theilmeier, G.5    Echtermeyer, F.6    Bruckner, P.7
  • 31
    • 0027239814 scopus 로고
    • The basement membranes of cryofixed or aldehyde-fixed, freeze-substituted tissues are composed of a lamina densa and do not contain a lamina lucida
    • Chan FL, Inoue S, Leblond CP. The basement membranes of cryofixed or aldehyde-fixed, freeze-substituted tissues are composed of a lamina densa and do not contain a lamina lucida. Cell Tissue Res 273: 41-52, 1993.
    • (1993) Cell Tissue Res , vol.273 , pp. 41-52
    • Chan, F.L.1    Inoue, S.2    Leblond, C.P.3
  • 32
    • 0016753740 scopus 로고
    • Permselectivity of the glomerular capillary wall. III. Restricted transport of polyanions
    • Chang RL, Deen WM, Robertson CR, Brenner BM. Permselectivity of the glomerular capillary wall. III. Restricted transport of polyanions. Kidney Int 8: 212-218, 1975.
    • (1975) Kidney Int , vol.8 , pp. 212-218
    • Chang, R.L.1    Deen, W.M.2    Robertson, C.R.3    Brenner, B.M.4
  • 33
    • 0034730249 scopus 로고    scopus 로고
    • Altering expression of alpha3beta1 integrin on podocytes of human and rats with diabetes
    • Chen HC, Chen CA, Guh JY, Chang JM, Shin SJ, Lai YH. Altering expression of alpha3beta1 integrin on podocytes of human and rats with diabetes. Life Sci 67: 2345-2353, 2000.
    • (2000) Life Sci , vol.67 , pp. 2345-2353
    • Chen, H.C.1    Chen, C.A.2    Guh, J.Y.3    Chang, J.M.4    Shin, S.J.5    Lai, Y.H.6
  • 36
    • 77955093872 scopus 로고    scopus 로고
    • The glomerulus-a view from the outside-the podocyte
    • Cheng H, Harris RC. The glomerulus-a view from the outside-the podocyte. Int J Biochem Cell Biol 42: 1380-1387, 2010.
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1380-1387
    • Cheng, H.1    Harris, R.C.2
  • 37
    • 0018756482 scopus 로고
    • Glomerulopathy in rats with streptozotocin diabetes. Accumulation of glomerular basement membrane analogous to human diabetic nephropathy
    • Cohen MP, Klein CV. Glomerulopathy in rats with streptozotocin diabetes. Accumulation of glomerular basement membrane analogous to human diabetic nephropathy. J Exp Med 149: 623-631, 1979.
    • (1979) J Exp Med , vol.149 , pp. 623-631
    • Cohen, M.P.1    Klein, C.V.2
  • 38
    • 0024202717 scopus 로고
    • Undersulfation of glomerular basement membrane heparan sulfate in experimental diabetes and lack of correction with aldose reductase inhibition
    • Cohen MP, Klepser H, Wu VY. Undersulfation of glomerular basement membrane heparan sulfate in experimental diabetes and lack of correction with aldose reductase inhibition. Diabetes 37: 1324-1327, 1988.
    • (1988) Diabetes , vol.37 , pp. 1324-1327
    • Cohen, M.P.1    Klepser, H.2    Wu, V.Y.3
  • 39
    • 0019730380 scopus 로고
    • [(35)S]sulfate incorporation into glomerular basement membrane glycosaminoglycans is decreased in experimental diabetes
    • Cohen MP, Surma ML. [(35)S]sulfate incorporation into glomerular basement membrane glycosaminoglycans is decreased in experimental diabetes. J Lab Clin Med 98: 715-722, 1981.
    • (1981) J Lab Clin Med , vol.98 , pp. 715-722
    • Cohen, M.P.1    Surma, M.L.2
  • 41
    • 0036840074 scopus 로고    scopus 로고
    • Glomerular hypertrophy is associated with hyperinsulinemia and precedes overt diabetes in aging rhesus monkeys
    • Cusumano AM, Bodkin NL, Hansen BC, Iotti R, Owens J, Klotman PE, Kopp JB. Glomerular hypertrophy is associated with hyperinsulinemia and precedes overt diabetes in aging rhesus monkeys. Am J Kidney Dis 40: 1075-1085, 2002.
    • (2002) Am J Kidney Dis , vol.40 , pp. 1075-1085
    • Cusumano, A.M.1    Bodkin, N.L.2    Hansen, B.C.3    Iotti, R.4    Owens, J.5    Klotman, P.E.6    Kopp, J.B.7
  • 44
    • 0025435526 scopus 로고
    • Ultrastructural distribution of glomerular basement membrane components in experimental diabetes
    • Desjardins M, Bendayan M. Ultrastructural distribution of glomerular basement membrane components in experimental diabetes. Diabetes Res 14: 65-73, 1990.
    • (1990) Diabetes Res , vol.14 , pp. 65-73
    • Desjardins, M.1    Bendayan, M.2
  • 45
    • 0034913347 scopus 로고    scopus 로고
    • Elevated matrix metalloproteinase-2 and -9 in urine, but not in serum, are markers of type 1 diabetic nephropathy
    • Diamant M, Hanemaaijer R, Verheijen JH, Smit JW, Radder JK, Lemkes HH. Elevated matrix metalloproteinase-2 and -9 in urine, but not in serum, are markers of type 1 diabetic nephropathy. Diabet Med 18:423-424, 2001.
    • (2001) Diabet Med , vol.18 , pp. 423-424
    • Diamant, M.1    Hanemaaijer, R.2    Verheijen, J.H.3    Smit, J.W.4    Radder, J.K.5    Lemkes, H.H.6
  • 46
    • 80053052721 scopus 로고    scopus 로고
    • Podocytopathy in diabetes: A metabolic and endocrine disorder
    • Diez-Sampedro A, Lenz O, Fornoni A. Podocytopathy in diabetes: a metabolic and endocrine disorder. Am J Kidney Dis 58: 637-646, 2011.
    • (2011) Am J Kidney Dis , vol.58 , pp. 637-646
    • Diez-Sampedro, A.1    Lenz, O.2    Fornoni, A.3
  • 48
    • 33644766738 scopus 로고    scopus 로고
    • Assessment of 115 candidate genes for diabetic nephropathy by transmission/ disequilibrium test
    • Ewens KG, George RA, Sharma K, Ziyadeh FN, Spielman RS. Assessment of 115 candidate genes for diabetic nephropathy by transmission/ disequilibrium test. Diabetes 54: 3305-3318, 2005.
    • (2005) Diabetes , vol.54 , pp. 3305-3318
    • Ewens, K.G.1    George, R.A.2    Sharma, K.3    Ziyadeh, F.N.4    Spielman, R.S.5
  • 49
    • 33746770477 scopus 로고    scopus 로고
    • The glomerular basement membrane: Not gone, just forgotten
    • Farquhar MG. The glomerular basement membrane: not gone, just forgotten. J Clin Invest 116: 2090-2093, 2006.
    • (2006) J Clin Invest , vol.116 , pp. 2090-2093
    • Farquhar, M.G.1
  • 50
    • 84950383730 scopus 로고
    • Diabetic glomerulosclerosis:Electron and light microscopic studies
    • Farquhar MG, Hopper J Jr, Moon HD. Diabetic glomerulosclerosis:electron and light microscopic studies. Am J Pathol 35: 721-753, 1959.
    • (1959) Am J Pathol , vol.35 , pp. 721-753
    • Farquhar, M.G.1    Hopper Jr, J.2    Moon, H.D.3
  • 51
    • 0034672644 scopus 로고    scopus 로고
    • Generation and degradation of human endostatin proteins by various proteinases
    • Ferreras M, Felbor U, Lenhard T, Olsen BR, Delaisse J. Generation and degradation of human endostatin proteins by various proteinases. FEBS Lett 486: 247-251, 2000.
    • (2000) FEBS Lett , vol.486 , pp. 247-251
    • Ferreras, M.1    Felbor, U.2    Lenhard, T.3    Olsen, B.R.4    Delaisse, J.5
  • 53
    • 0028556832 scopus 로고
    • Glomerular structure in nonproteinuric IDDM patients with various levels of albuminuria
    • Fioretto P, Steffes MW, Mauer M. Glomerular structure in nonproteinuric IDDM patients with various levels of albuminuria. Diabetes 43:1358-1364, 1994.
    • (1994) Diabetes , vol.43 , pp. 1358-1364
    • Fioretto, P.1    Steffes, M.W.2    Mauer, M.3
  • 54
    • 84872313601 scopus 로고    scopus 로고
    • Mechanisms of diabetic complications
    • Forbes JM, Cooper ME. Mechanisms of diabetic complications. Physiol Rev 93: 137-188, 2013.
    • (2013) Physiol Rev , vol.93 , pp. 137-188
    • Forbes, J.M.1    Cooper, M.E.2
  • 56
    • 38949210220 scopus 로고    scopus 로고
    • Effect of a multifactorial intervention on mortality in type 2 diabetes
    • Gaede P, Lund-Andersen H, Parving HH, Pedersen O. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med 358: 580-591, 2008.
    • (2008) N Engl J Med , vol.358 , pp. 580-591
    • Gaede, P.1    Lund-Andersen, H.2    Parving, H.H.3    Pedersen, O.4
  • 57
    • 67651089928 scopus 로고    scopus 로고
    • Glomerular filtration is normal in the absence of both agrin and perlecanheparan sulfate from the glomerular basement membrane
    • Goldberg S, Harvey SJ, Cunningham J, Tryggvason K, Miner JH. Glomerular filtration is normal in the absence of both agrin and perlecanheparan sulfate from the glomerular basement membrane. Nephrol Dial Transplant 24: 2044-2051, 2009.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2044-2051
    • Goldberg, S.1    Harvey, S.J.2    Cunningham, J.3    Tryggvason, K.4    Miner, J.H.5
  • 58
    • 84857243208 scopus 로고    scopus 로고
    • Cell biology and pathology of podocytes
    • Greka A, Mundel P. Cell biology and pathology of podocytes. Ann Rev Physiol 74: 299-323, 2012.
    • (2012) Ann Rev Physiol , vol.74 , pp. 299-323
    • Greka, A.1    Mundel, P.2
  • 60
    • 0032815533 scopus 로고    scopus 로고
    • Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane
    • Groffen AJ, Veerkamp JH, Monnens LA, van den Heuvel LP. Recent insights into the structure and functions of heparan sulfate proteoglycans in the human glomerular basement membrane. Nephrol Dial Transplant 14: 2119-2129, 1999.
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 2119-2129
    • Groffen, A.J.1    Veerkamp, J.H.2    Monnens, L.A.3    Van Den Heuvel, L.P.4
  • 61
    • 37349123995 scopus 로고    scopus 로고
    • Inherited diseases of the glomerular basement membrane
    • Gubler MC. Inherited diseases of the glomerular basement membrane. Nat Clin Pract Nephrol 4: 24-37, 2008.
    • (2008) Nat Clin Pract Nephrol , vol.4 , pp. 24-37
    • Gubler, M.C.1
  • 62
    • 0035152114 scopus 로고    scopus 로고
    • The distribution and regulation of integrin-linked kinase in normal and diabetic kidneys
    • Guo L, Sanders PW, Woods A, Wu C. The distribution and regulation of integrin-linked kinase in normal and diabetic kidneys. Am J Pathol 159: 1735-1742, 2001.
    • (2001) Am J Pathol , vol.159 , pp. 1735-1742
    • Guo, L.1    Sanders, P.W.2    Woods, A.3    Wu, C.4
  • 63
    • 33750121618 scopus 로고    scopus 로고
    • An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy
    • Han SY, Jee YH, Han KH, Kang YS, Kim HK, Han JY, Kim YS, Cha DR. An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy. Nephrol Dial Transplant 21: 2406-2416, 2006.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 2406-2416
    • Han, S.Y.1    Jee, Y.H.2    Han, K.H.3    Kang, Y.S.4    Kim, H.K.5    Han, J.Y.6    Kim, Y.S.7    Cha, D.R.8
  • 64
    • 42149122041 scopus 로고    scopus 로고
    • Properties of the glomerular barrier and mechanisms of proteinuria
    • Haraldsson B, Nystrom J, Deen WM. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88: 451-487, 2008.
    • (2008) Physiol Rev , vol.88 , pp. 451-487
    • Haraldsson, B.1    Nystrom, J.2    Deen, W.M.3
  • 66
    • 28444441957 scopus 로고    scopus 로고
    • Tetraspanin functions and associated microdomains
    • Hemler ME. Tetraspanin functions and associated microdomains. Nat Rev Mol Cell Biol 6: 801-811, 2005.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 801-811
    • Hemler, M.E.1
  • 67
    • 0027209657 scopus 로고
    • Pores in the glomerular basement membrane revealed by ultrahigh-resolution scanning electron microscopy
    • Hironaka K, Makino H, Yamasaki Y, Ota Z. Pores in the glomerular basement membrane revealed by ultrahigh-resolution scanning electron microscopy. Nephron 64: 647-649, 1993.
    • (1993) Nephron , vol.64 , pp. 647-649
    • Hironaka, K.1    Makino, H.2    Yamasaki, Y.3    Ota, Z.4
  • 70
    • 70849099495 scopus 로고    scopus 로고
    • The extracellular matrix: Not just pretty fibrils
    • Hynes RO. The extracellular matrix: not just pretty fibrils. Science 326:1216-1219, 2009.
    • (2009) Science , vol.326 , pp. 1216-1219
    • Hynes, R.O.1
  • 71
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 110: 673-687, 2002.
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 72
    • 0036420353 scopus 로고    scopus 로고
    • Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes
    • Iglesias-de la Cruz MC, Ziyadeh FN, Isono M, Kouahou M, Han DC, Kalluri R, Mundel P, Chen S. Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes. Kidney Int 62: 901-913, 2002.
    • (2002) Kidney Int , vol.62 , pp. 901-913
    • Iglesias-de La Cruz, M.C.1    Ziyadeh, F.N.2    Isono, M.3    Kouahou, M.4    Han, D.C.5    Kalluri, R.6    Mundel, P.7    Chen, S.8
  • 74
    • 0029782089 scopus 로고    scopus 로고
    • High-resolution ultrastructural study of the rat glomerular basement membrane in aminonucleoside nephrosis
    • Inoue S, Bendayan M. High-resolution ultrastructural study of the rat glomerular basement membrane in aminonucleoside nephrosis. Ultrastruct Pathol 20: 409-416, 1996.
    • (1996) Ultrastruct Pathol , vol.20 , pp. 409-416
    • Inoue, S.1    Bendayan, M.2
  • 75
    • 33746730496 scopus 로고    scopus 로고
    • Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier
    • Jarad G, Cunningham J, Shaw AS, Miner JH. Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier. J Clin Invest 116: 2272-2279, 2006.
    • (2006) J Clin Invest , vol.116 , pp. 2272-2279
    • Jarad, G.1    Cunningham, J.2    Shaw, A.S.3    Miner, J.H.4
  • 76
    • 79954504238 scopus 로고    scopus 로고
    • Dystroglycan does not contribute significantly to kidney development or function, in health or after injury
    • Jarad G, Pippin JW, Shankland SJ, Kreidberg JA, Miner JH. Dystroglycan does not contribute significantly to kidney development or function, in health or after injury. Am J Physiol Renal Physiol 300:F811-F820, 2011.
    • (2011) Am J Physiol Renal Physiol , vol.300 , pp. F811-F820
    • Jarad, G.1    Pippin, J.W.2    Shankland, S.J.3    Kreidberg, J.A.4    Miner, J.H.5
  • 77
    • 45249108429 scopus 로고    scopus 로고
    • Proteinuria in diabetic kidney disease: A mechanistic viewpoint
    • Jefferson JA, Shankland SJ, Pichler RH. Proteinuria in diabetic kidney disease: a mechanistic viewpoint. Kidney Int 74: 22-36, 2008.
    • (2008) Kidney Int , vol.74 , pp. 22-36
    • Jefferson, J.A.1    Shankland, S.J.2    Pichler, R.H.3
  • 78
    • 37849026460 scopus 로고    scopus 로고
    • Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus
    • Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH Jr, Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev Biol 313: 584-593, 2008.
    • (2008) Dev Biol , vol.313 , pp. 584-593
    • Kanasaki, K.1    Kanda, Y.2    Palmsten, K.3    Tanjore, H.4    Lee, S.B.5    Lebleu, V.S.6    Gattone Jr, V.H.7    Kalluri, R.8
  • 79
    • 84924083288 scopus 로고    scopus 로고
    • Continuum of historical controversies regarding the structural- functional relationship of the glomerular ultrafiltration unit
    • Kanwar YS. Continuum of historical controversies regarding the structural- functional relationship of the glomerular ultrafiltration unit. Am J Physiol Renal Physiol 308:F420-F424, 2015.
    • (2015) Am J Physiol Renal Physiol , vol.308 , pp. F420-F424
    • Kanwar, Y.S.1
  • 80
    • 34547669237 scopus 로고    scopus 로고
    • Contribution of proteoglycans towards the integrated functions of renal glomerular capillaries: A historical perspective
    • Kanwar YS, Danesh FR, Chugh SS. Contribution of proteoglycans towards the integrated functions of renal glomerular capillaries: a historical perspective. Am J Pathol 171: 9-13, 2007.
    • (2007) Am J Pathol , vol.171 , pp. 9-13
    • Kanwar, Y.S.1    Danesh, F.R.2    Chugh, S.S.3
  • 81
    • 0020287270 scopus 로고
    • Clogging of the glomerular basement membrane
    • Kanwar YS, Rosenzweig LJ. Clogging of the glomerular basement membrane. J Cell Biol 93: 489-494, 1982.
    • (1982) J Cell Biol , vol.93 , pp. 489-494
    • Kanwar, Y.S.1    Rosenzweig, L.J.2
  • 82
    • 79751477368 scopus 로고    scopus 로고
    • A glimpse of various pathogenetic mechanisms of diabetic nephropathy
    • Kanwar YS, Sun L, Xie P, Liu FY, Chen S. A glimpse of various pathogenetic mechanisms of diabetic nephropathy. Annu Rev Pathol 6:395-423, 2011.
    • (2011) Annu Rev Pathol , vol.6 , pp. 395-423
    • Kanwar, Y.S.1    Sun, L.2    Xie, P.3    Liu, F.Y.4    Chen, S.5
  • 83
    • 4944239350 scopus 로고    scopus 로고
    • CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin
    • Karamatic Crew V, Burton N, Kagan A, Green CA, Levene C, Flinter F, Brady RL, Daniels G, Anstee DJ. CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin. Blood 104: 2217-2223, 2004.
    • (2004) Blood , vol.104 , pp. 2217-2223
    • Karamatic Crew, V.1    Burton, N.2    Kagan, A.3    Green, C.A.4    Levene, C.5    Flinter, F.6    Brady, R.L.7    Daniels, G.8    Anstee, D.J.9
  • 85
    • 0028831889 scopus 로고
    • Podocytes loose their adhesive phenotype in focal segmental glomerulosclerosis
    • Kemeny E, Mihatsch MJ, Durmuller U, Gudat F. Podocytes loose their adhesive phenotype in focal segmental glomerulosclerosis. Clin Nephrol 43: 71-83, 1995.
    • (1995) Clin Nephrol , vol.43 , pp. 71-83
    • Kemeny, E.1    Mihatsch, M.J.2    Durmuller, U.3    Gudat, F.4
  • 86
    • 0034307327 scopus 로고    scopus 로고
    • Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase
    • Kim YM, Jang JW, Lee OH, Yeon J, Choi EY, Kim KW, Lee ST, Kwon YG. Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res 60: 5410-5413, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5410-5413
    • Kim, Y.M.1    Jang, J.W.2    Lee, O.H.3    Yeon, J.4    Choi, E.Y.5    Kim, K.W.6    Lee, S.T.7    Kwon, Y.G.8
  • 87
    • 79953149683 scopus 로고    scopus 로고
    • Lack of collagen XVIII long isoforms affects kidney podocytes, whereas the short form is needed in the proximal tubular basement membrane
    • Kinnunen AI, Sormunen R, Elamaa H, Seppinen L, Miller RT, Ninomiya Y, Janmey PA, Pihlajaniemi T. Lack of collagen XVIII long isoforms affects kidney podocytes, whereas the short form is needed in the proximal tubular basement membrane. J Biol Chem 286: 7755-7764, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 7755-7764
    • Kinnunen, A.I.1    Sormunen, R.2    Elamaa, H.3    Seppinen, L.4    Miller, R.T.5    Ninomiya, Y.6    Janmey, P.A.7    Pihlajaniemi, T.8
  • 88
    • 0026000263 scopus 로고
    • Distribution of the alpha 1-alpha 6 integrin subunits in human developing and term placenta
    • Korhonen M, Ylanne J, Laitinen L, Cooper HM, Quaranta V, Virtanen I. Distribution of the alpha 1-alpha 6 integrin subunits in human developing and term placenta. Lab Invest 65: 347-356, 1991.
    • (1991) Lab Invest , vol.65 , pp. 347-356
    • Korhonen, M.1    Ylanne, J.2    Laitinen, L.3    Cooper, H.M.4    Quaranta, V.5    Virtanen, I.6
  • 89
    • 0025345399 scopus 로고
    • Distribution of beta 1 and beta 3 integrins in human fetal and adult kidney
    • Korhonen M, Ylanne J, Laitinen L, Virtanen I. Distribution of beta 1 and beta 3 integrins in human fetal and adult kidney. Lab Invest 62:616-625, 1990.
    • (1990) Lab Invest , vol.62 , pp. 616-625
    • Korhonen, M.1    Ylanne, J.2    Laitinen, L.3    Virtanen, I.4
  • 92
    • 0022363373 scopus 로고
    • Ultrastructural organization of the glomerular basement membrane as revealed by a deep-etch replica method
    • Kubosawa H, Kondo Y. Ultrastructural organization of the glomerular basement membrane as revealed by a deep-etch replica method. Cell Tissue Res 242: 33-39, 1985.
    • (1985) Cell Tissue Res , vol.242 , pp. 33-39
    • Kubosawa, H.1    Kondo, Y.2
  • 97
  • 98
    • 33845998580 scopus 로고    scopus 로고
    • ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome
    • Liu G, Clement LC, Kanwar YS, Avila-Casado C, Chugh SS. ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. J Biol Chem 281: 39681-39692, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 39681-39692
    • Liu, G.1    Clement, L.C.2    Kanwar, Y.S.3    Avila-Casado, C.4    Chugh, S.S.5
  • 100
    • 84858307317 scopus 로고    scopus 로고
    • Signaling mechanisms in the regulation of renal matrix metabolism in diabetes
    • Mariappan MM. Signaling mechanisms in the regulation of renal matrix metabolism in diabetes. Exp Diabetes Res 2012:749812, 2012.
    • (2012) Exp Diabetes Res , vol.2012 , pp. 749812
    • Mariappan, M.M.1
  • 101
    • 34447116931 scopus 로고    scopus 로고
    • Cell cycle regulatory proteins in podocyte health and disease
    • Marshall CB, Shankland SJ. Cell cycle regulatory proteins in podocyte health and disease. Nephron Exp Nephrol 106:e51-e59, 2007.
    • (2007) Nephron Exp Nephrol , vol.106 , pp. e51-e59
    • Marshall, C.B.1    Shankland, S.J.2
  • 102
    • 34548723974 scopus 로고    scopus 로고
    • The podocyte: A potential therapeutic target in diabetic nephropathy?
    • Marshall SM. The podocyte: a potential therapeutic target in diabetic nephropathy? Curr Pharm Des 13: 2713-2720, 2007.
    • (2007) Curr Pharm Des , vol.13 , pp. 2713-2720
    • Marshall, S.M.1
  • 104
    • 0018126607 scopus 로고
    • Effects of pancreatic islet transplantation on the increased urinary albumin excretion rates in intact and uninephrectomized rats with diabetes mellitus
    • Mauer SM, Brown DM, Matas AJ, Steffes MW. Effects of pancreatic islet transplantation on the increased urinary albumin excretion rates in intact and uninephrectomized rats with diabetes mellitus. Diabetes 27:959-964, 1978.
    • (1978) Diabetes , vol.27 , pp. 959-964
    • Mauer, S.M.1    Brown, D.M.2    Matas, A.J.3    Steffes, M.W.4
  • 106
    • 0032960244 scopus 로고    scopus 로고
    • Glomerular capillary wall basement membrane really does have laminae lucidae: A defense
    • McAdams AJ. Glomerular capillary wall basement membrane really does have laminae lucidae: A defense. Pediatr Dev Pathol 2: 260-263, 1999.
    • (1999) Pediatr Dev Pathol , vol.2 , pp. 260-263
    • McAdams, A.J.1
  • 107
    • 0030717738 scopus 로고    scopus 로고
    • Morphogenesis of the glomerular filter: The synchronous assembly and maturation of two distinct extracellular matrices
    • McCarthy KJ. Morphogenesis of the glomerular filter: the synchronous assembly and maturation of two distinct extracellular matrices. Microsc Res Tech 39: 233-253, 1997.
    • (1997) Microsc Res Tech , vol.39 , pp. 233-253
    • McCarthy, K.J.1
  • 108
    • 84856017650 scopus 로고    scopus 로고
    • The glomerular basement membrane as a model system to study the bioactivity of heparan sulfate glycosaminoglycans
    • McCarthy KJ, Wassenhove-McCarthy DJ. The glomerular basement membrane as a model system to study the bioactivity of heparan sulfate glycosaminoglycans. Microsc Microanal 18: 3-21, 2012.
    • (2012) Microsc Microanal , vol.18 , pp. 3-21
    • McCarthy, K.J.1    Wassenhove-McCarthy, D.J.2
  • 109
    • 34547348003 scopus 로고    scopus 로고
    • Immunopathology and molecular diagnosis of autoimmune bullous diseases
    • Mihai S, Sitaru C. Immunopathology and molecular diagnosis of autoimmune bullous diseases. J Cell Mol Med 11: 462-481, 2007.
    • (2007) J Cell Mol Med , vol.11 , pp. 462-481
    • Mihai, S.1    Sitaru, C.2
  • 110
    • 84859814741 scopus 로고    scopus 로고
    • The glomerular basement membrane
    • Miner JH. The glomerular basement membrane. Exp Cell Res 318:973-978, 2012.
    • (2012) Exp Cell Res , vol.318 , pp. 973-978
    • Miner, J.H.1
  • 111
    • 47349130832 scopus 로고    scopus 로고
    • Glomerular filtration: The charge debate charges ahead
    • Miner JH. Glomerular filtration: the charge debate charges ahead. Kidney Int 74: 259-261, 2008.
    • (2008) Kidney Int , vol.74 , pp. 259-261
    • Miner, J.H.1
  • 112
    • 79957565394 scopus 로고    scopus 로고
    • Organogenesis of the kidney glomerulus: Focus on the glomerular basement membrane
    • Miner JH. Organogenesis of the kidney glomerulus: focus on the glomerular basement membrane. Organogenesis 7: 75-82, 2011.
    • (2011) Organogenesis , vol.7 , pp. 75-82
    • Miner, J.H.1
  • 113
    • 0033460287 scopus 로고    scopus 로고
    • Renal basement membrane components
    • Miner JH. Renal basement membrane components. Kidney Int 56:2016-2024, 1999.
    • (1999) Kidney Int , vol.56 , pp. 2016-2024
    • Miner, J.H.1
  • 114
    • 0034650304 scopus 로고    scopus 로고
    • Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane
    • Miner JH, Li C. Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol 217: 278-289, 2000.
    • (2000) Dev Biol , vol.217 , pp. 278-289
    • Miner, J.H.1    Li, C.2
  • 115
    • 0037369808 scopus 로고    scopus 로고
    • The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo
    • Miosge N, Simniok T, Sprysch P, Herken R. The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo. J Histochem Cytochem 51: 285-296, 2003.
    • (2003) J Histochem Cytochem , vol.51 , pp. 285-296
    • Miosge, N.1    Simniok, T.2    Sprysch, P.3    Herken, R.4
  • 116
    • 0141678253 scopus 로고    scopus 로고
    • Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury
    • Mishra J, Ma Q, Prada A, Mitsnefes M, Zahedi K, Yang J, Barasch J, Devarajan P. Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J Am Soc Nephrol 14: 2534-2543, 2003.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2534-2543
    • Mishra, J.1    Ma, Q.2    Prada, A.3    Mitsnefes, M.4    Zahedi, K.5    Yang, J.6    Barasch, J.7    Devarajan, P.8
  • 117
    • 0021322084 scopus 로고
    • Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes
    • Mogensen CE. Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. N Engl J Med 310: 356-360, 1984.
    • (1984) N Engl J Med , vol.310 , pp. 356-360
    • Mogensen, C.E.1
  • 118
    • 0032989007 scopus 로고    scopus 로고
    • Microalbuminuria, blood pressure and diabetic renal disease: Origin and development of ideas
    • Mogensen CE. Microalbuminuria, blood pressure and diabetic renal disease: origin and development of ideas. Diabetologia 42: 263-285, 1999.
    • (1999) Diabetologia , vol.42 , pp. 263-285
    • Mogensen, C.E.1
  • 121
    • 38149079892 scopus 로고    scopus 로고
    • The role of heparan sulfate in the glomerular basement membrane
    • Morita H, Yoshimura A, Kimata K. The role of heparan sulfate in the glomerular basement membrane. Kidney Int 73: 247-248, 2008.
    • (2008) Kidney Int , vol.73 , pp. 247-248
    • Morita, H.1    Yoshimura, A.2    Kimata, K.3
  • 122
    • 0030658055 scopus 로고    scopus 로고
    • Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility
    • Mott JD, Khalifah RG, Nagase H, Shield CF, 3rd Hudson JK, Hudson BG. Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility. Kidney Int 52: 1302-1312, 1997.
    • (1997) Kidney Int , vol.52 , pp. 1302-1312
    • Mott, J.D.1    Khalifah, R.G.2    Nagase, H.3    Shield, C.F.4    Hudson, J.K.5    Hudson, B.G.6
  • 124
    • 84867347643 scopus 로고    scopus 로고
    • Morphologic features of declining renal function in type 1 diabetes
    • Najafian B, Mauer M. Morphologic features of declining renal function in type 1 diabetes. Semin Nephrol 32: 415-422, 2012.
    • (2012) Semin Nephrol , vol.32 , pp. 415-422
    • Najafian, B.1    Mauer, M.2
  • 125
    • 0033855993 scopus 로고    scopus 로고
    • Effect of the antiplatelet drug dilazep dihydrochloride on urinary podocytes in patients in the early stage of diabetic nephropathy
    • Nakamura T, Ushiyama C, Shimada N, Sekizuka K, Ebihara I, Hara M, Koide H. Effect of the antiplatelet drug dilazep dihydrochloride on urinary podocytes in patients in the early stage of diabetic nephropathy. Diabetes Care 23: 1168-1171, 2000.
    • (2000) Diabetes Care , vol.23 , pp. 1168-1171
    • Nakamura, T.1    Ushiyama, C.2    Shimada, N.3    Sekizuka, K.4    Ebihara, I.5    Hara, M.6    Koide, H.7
  • 127
    • 0025943567 scopus 로고
    • Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions
    • Nerlich A, Schleicher E. Immunohistochemical localization of extracellular matrix components in human diabetic glomerular lesions. Am J Pathol 139: 889-899, 1991.
    • (1991) Am J Pathol , vol.139 , pp. 889-899
    • Nerlich, A.1    Schleicher, E.2
  • 129
    • 0029127384 scopus 로고
    • The renal glomerulus of mice lacking s-laminin/laminin beta 2: Nephrosis despite molecular compensation by laminin beta 1
    • Noakes PG, Miner JH, Gautam M, Cunningham JM, Sanes JR, Merlie JP. The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat Genet 10: 400-406, 1995.
    • (1995) Nat Genet , vol.10 , pp. 400-406
    • Noakes, P.G.1    Miner, J.H.2    Gautam, M.3    Cunningham, J.M.4    Sanes, J.R.5    Merlie, J.P.6
  • 130
    • 0037590989 scopus 로고    scopus 로고
    • Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13
    • Nyberg P, Heikkila P, Sorsa T, Luostarinen J, Heljasvaara R, Stenman UH, Pihlajaniemi T, Salo T. Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13. J Biol Chem 278: 22404-22411, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 22404-22411
    • Nyberg, P.1    Heikkila, P.2    Sorsa, T.3    Luostarinen, J.4    Heljasvaara, R.5    Stenman, U.H.6    Pihlajaniemi, T.7    Salo, T.8
  • 132
    • 0016709830 scopus 로고
    • Glomerular size and structure in diabetes mellitus. I. Early abnormalities
    • Osterby R, Gundersen HJ. Glomerular size and structure in diabetes mellitus. I. Early abnormalities. Diabetologia 11: 225-229, 1975.
    • (1975) Diabetologia , vol.11 , pp. 225-229
    • Osterby, R.1    Gundersen, H.J.2
  • 134
    • 0019952941 scopus 로고
    • Effect of diabetes on the glycosaminoglycan component of the human glomerular basement membrane
    • Parthasarathy N, Spiro RG. Effect of diabetes on the glycosaminoglycan component of the human glomerular basement membrane. Diabetes 31: 738-741, 1982.
    • (1982) Diabetes , vol.31 , pp. 738-741
    • Parthasarathy, N.1    Spiro, R.G.2
  • 136
    • 77952305808 scopus 로고    scopus 로고
    • Molecular make-up of the glomerular filtration barrier
    • Patrakka J, Tryggvason K. Molecular make-up of the glomerular filtration barrier. Biochem Biophys Res Commun 396: 164-169, 2010.
    • (2010) Biochem Biophys Res Commun , vol.396 , pp. 164-169
    • Patrakka, J.1    Tryggvason, K.2
  • 137
    • 0037207471 scopus 로고    scopus 로고
    • Cell biology of the glomerular podocyte
    • Pavenstadt H, Kriz W, Kretzler M. Cell biology of the glomerular podocyte. Physiol Rev 83: 253-307, 2003.
    • (2003) Physiol Rev , vol.83 , pp. 253-307
    • Pavenstadt, H.1    Kriz, W.2    Kretzler, M.3
  • 138
    • 32544436771 scopus 로고    scopus 로고
    • The course of diabetic glomerulopathy in patients with type I diabetes: A 6-year follow-up with serial biopsies
    • Perrin NE, Torbjornsdotter TB, Jaremko GA, Berg UB. The course of diabetic glomerulopathy in patients with type I diabetes: a 6-year follow-up with serial biopsies. Kidney Int 69: 699-705, 2006.
    • (2006) Kidney Int , vol.69 , pp. 699-705
    • Perrin, N.E.1    Torbjornsdotter, T.B.2    Jaremko, G.A.3    Berg, U.B.4
  • 140
    • 4744349621 scopus 로고
    • An unusual congenital and familial congenital malformative combination involving the eye and kidney
    • Pierson M, Cordier J, Hervouuet F, Rauber G. An unusual congenital and familial congenital malformative combination involving the eye and kidney. J Genet Hum 12: 184-213, 1963.
    • (1963) J Genet Hum , vol.12 , pp. 184-213
    • Pierson, M.1    Cordier, J.2    Hervouuet, F.3    Rauber, G.4
  • 141
    • 0036724859 scopus 로고    scopus 로고
    • Anti-glomerular basement membrane nephritis and bullous pemphigoid caused by distinct anti-alpha 3(IV)NC1 and anti-BP180 antibodies in a patient with Crohn’s disease
    • Plaisier E, Borradori L, Hellmark T, Wattiaux MJ, Flageul B, Mougenot B, Ronco P. Anti-glomerular basement membrane nephritis and bullous pemphigoid caused by distinct anti-alpha 3(IV)NC1 and anti-BP180 antibodies in a patient with Crohn’s disease. Am J Kidney Dis 40: 649-654, 2002.
    • (2002) Am J Kidney Dis , vol.40 , pp. 649-654
    • Plaisier, E.1    Borradori, L.2    Hellmark, T.3    Wattiaux, M.J.4    Flageul, B.5    Mougenot, B.6    Ronco, P.7
  • 142
    • 84880133356 scopus 로고    scopus 로고
    • Temporal profile of diabetic nephropathy pathologic changes
    • Ponchiardi C, Mauer M, Najafian B. Temporal profile of diabetic nephropathy pathologic changes. Curr Diab Rep 13: 592-599, 2013.
    • (2013) Curr Diab Rep , vol.13 , pp. 592-599
    • Ponchiardi, C.1    Mauer, M.2    Najafian, B.3
  • 145
    • 84855454846 scopus 로고    scopus 로고
    • Hold tight or you’ll fall off: CD151 helps podocytes stick in high-pressure situations
    • Pozzi A, Zent R. Hold tight or you’ll fall off: CD151 helps podocytes stick in high-pressure situations. J Clin Invest 122: 13-16, 2012.
    • (2012) J Clin Invest , vol.122 , pp. 13-16
    • Pozzi, A.1    Zent, R.2
  • 146
    • 84879967784 scopus 로고    scopus 로고
    • Integrins in kidney disease
    • Pozzi A, Zent R. Integrins in kidney disease. J Am Soc Nephrol 24:1034-1039, 2013.
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1034-1039
    • Pozzi, A.1    Zent, R.2
  • 147
    • 0017660779 scopus 로고
    • Studies on the metabolism of the renal glomerular basement membrane. Turnover measurements in the rat with the use of radiolabeled amino acids
    • Price RG, Spiro RG. Studies on the metabolism of the renal glomerular basement membrane. Turnover measurements in the rat with the use of radiolabeled amino acids. J Biol Chem 252: 8597-8602, 1977.
    • (1977) J Biol Chem , vol.252 , pp. 8597-8602
    • Price, R.G.1    Spiro, R.G.2
  • 149
    • 0025618250 scopus 로고
    • The laminae rarae of the glomerular basement membrane. Their manifestation depends on the histochemical and histological techniques
    • Reale E, Luciano L. The laminae rarae of the glomerular basement membrane. Their manifestation depends on the histochemical and histological techniques. Contrib Nephrol 80: 32-40, 1990.
    • (1990) Contrib Nephrol , vol.80 , pp. 32-40
    • Reale, E.1    Luciano, L.2
  • 150
    • 0019302981 scopus 로고
    • Assembly of the glomerular filtration surface. Differentiation of anionic sites in glomerular capillaries of newborn rat kidney
    • Reeves WH, Kanwar YS, Farquhar MG. Assembly of the glomerular filtration surface. Differentiation of anionic sites in glomerular capillaries of newborn rat kidney. J Cell Biol 85: 735-753, 1980.
    • (1980) J Cell Biol , vol.85 , pp. 735-753
    • Reeves, W.H.1    Kanwar, Y.S.2    Farquhar, M.G.3
  • 151
    • 0031033557 scopus 로고    scopus 로고
    • Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus
    • Regoli M, Bendayan M. Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus. Diabetologia 40: 15-22, 1997.
    • (1997) Diabetologia , vol.40 , pp. 15-22
    • Regoli, M.1    Bendayan, M.2
  • 152
    • 0024419983 scopus 로고
    • Bullous pemphigoid-associated nephropathy:Report of two cases and review of the literature
    • Ross EA, Ahmed AR. Bullous pemphigoid-associated nephropathy:report of two cases and review of the literature. Am J Kidney Dis 14:225-229, 1989.
    • (1989) Am J Kidney Dis , vol.14 , pp. 225-229
    • Ross, E.A.1    Ahmed, A.R.2
  • 155
    • 84875702158 scopus 로고    scopus 로고
    • Cell-matrix adhesion of podocytes in physiology and disease
    • Sachs N, Sonnenberg A. Cell-matrix adhesion of podocytes in physiology and disease. Nat Rev Nephrol 9: 200-210, 2013.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 200-210
    • Sachs, N.1    Sonnenberg, A.2
  • 156
    • 0032479999 scopus 로고    scopus 로고
    • Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin
    • Sasaki T, Fukai N, Mann K, Gohring W, Olsen BR, Timpl R. Structure, function and tissue forms of the C-terminal globular domain of collagen XVIII containing the angiogenesis inhibitor endostatin. EMBO J 17: 4249-4256, 1998.
    • (1998) EMBO J , vol.17 , pp. 4249-4256
    • Sasaki, T.1    Fukai, N.2    Mann, K.3    Gohring, W.4    Olsen, B.R.5    Timpl, R.6
  • 157
    • 0036785584 scopus 로고    scopus 로고
    • Gene structure and functional analysis of the mouse nidogen-2 gene: Nidogen-2 is not essential for basement membrane formation in mice
    • Schymeinsky J, Nedbal S, Miosge N, Poschl E, Rao C, Beier DR, Skarnes WC, Timpl R, Bader BL. Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice. Mol Cell Biol 22: 6820-6830, 2002.
    • (2002) Mol Cell Biol , vol.22 , pp. 6820-6830
    • Schymeinsky, J.1    Nedbal, S.2    Miosge, N.3    Poschl, E.4    Rao, C.5    Beier, D.R.6    Skarnes, W.C.7    Timpl, R.8    Bader, B.L.9
  • 158
    • 79952104610 scopus 로고    scopus 로고
    • The multiple functions of collagen XVIII in development and disease
    • Seppinen L, Pihlajaniemi T. The multiple functions of collagen XVIII in development and disease. Matrix Biol 30: 83-92, 2011.
    • (2011) Matrix Biol , vol.30 , pp. 83-92
    • Seppinen, L.1    Pihlajaniemi, T.2
  • 159
    • 0037389827 scopus 로고    scopus 로고
    • Why the kidney glomerulus does not clog: A gel permeation/ diffusion hypothesis of renal function
    • Smithies O. Why the kidney glomerulus does not clog: a gel permeation/ diffusion hypothesis of renal function. Proc Natl Acad Sci USA 100:4108-4113, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4108-4113
    • Smithies, O.1
  • 160
    • 0035722242 scopus 로고    scopus 로고
    • Glomerular endothelial cells and podocytes jointly synthesize laminin-1 and -11 chains
    • St. John PL, Abrahamson DR. Glomerular endothelial cells and podocytes jointly synthesize laminin-1 and -11 chains. Kidney Int 60: 1037-1046, 2001.
    • (2001) Kidney Int , vol.60 , pp. 1037-1046
    • John, P.L.1    Abrahamson, D.R.2
  • 161
    • 0035008793 scopus 로고    scopus 로고
    • Glomerular cell number in normal subjects and in type 1 diabetic patients
    • Steffes MW, Schmidt D, McCrery R, Basgen JM, International Diabetic Nephropathy Study Group. Glomerular cell number in normal subjects and in type 1 diabetic patients. Kidney Int 59: 2104-2113, 2001.
    • (2001) Kidney Int , vol.59 , pp. 2104-2113
    • Steffes, M.W.1    Schmidt, D.2    McCrery, R.3    Basgen, J.M.4
  • 163
    • 0037087710 scopus 로고    scopus 로고
    • Association of the tetraspanin CD151 with the lamininbinding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo
    • Sterk LM, Geuijen CA, van den Berg JG, Claessen N, Weening JJ, Sonnenberg A. Association of the tetraspanin CD151 with the lamininbinding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo. J Cell Sci 115: 1161-1173, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 1161-1173
    • Sterk, L.M.1    Geuijen, C.A.2    Van Den Berg, J.G.3    Claessen, N.4    Weening, J.J.5    Sonnenberg, A.6
  • 164
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteinases regulate cell behavior
    • Sternlicht MD, Werb Z. How matrix metalloproteinases regulate cell behavior. Annu Rev Cell Dev Biol 17: 463-516, 2001.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 165
    • 79952180728 scopus 로고    scopus 로고
    • The role of metabolic and haemodynamic factors in podocyte injury in diabetes
    • Stieger N, Worthmann K, Schiffer M. The role of metabolic and haemodynamic factors in podocyte injury in diabetes. Diabetes Metab Res Rev 27: 207-215, 2011.
    • (2011) Diabetes Metab Res Rev , vol.27 , pp. 207-215
    • Stieger, N.1    Worthmann, K.2    Schiffer, M.3
  • 168
    • 84880925050 scopus 로고    scopus 로고
    • The glomerular basement membrane as a barrier to albumin
    • Suh JH, Miner JH. The glomerular basement membrane as a barrier to albumin. Nat Rev Nephrol 9: 470-477, 2013.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 470-477
    • Suh, J.H.1    Miner, J.H.2
  • 170
    • 33744474294 scopus 로고    scopus 로고
    • Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats
    • Sun SZ, Wang Y, Li Q, Tian YJ, Liu MH, Yu YH. Effects of benazepril on renal function and kidney expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in diabetic rats. Chin Med J (Engl) 119: 814-821, 2006.
    • (2006) Chin Med J (Engl) , vol.119 , pp. 814-821
    • Sun, S.Z.1    Wang, Y.2    Li, Q.3    Tian, Y.J.4    Liu, M.H.5    Yu, Y.H.6
  • 171
    • 33644783770 scopus 로고    scopus 로고
    • Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy
    • Susztak K, Raff AC, Schiffer M, Bottinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 55: 225-233, 2006.
    • (2006) Diabetes , vol.55 , pp. 225-233
    • Susztak, K.1    Raff, A.C.2    Schiffer, M.3    Bottinger, E.P.4
  • 172
    • 84856514036 scopus 로고    scopus 로고
    • Acute and sustained actions of hyperglycaemia on endothelial and glomerular barrier permeability
    • Sward P, Rippe B. Acute and sustained actions of hyperglycaemia on endothelial and glomerular barrier permeability. Acta Physiol (Oxf) 204:294-307, 2012.
    • (2012) Acta Physiol (Oxf) , vol.204 , pp. 294-307
    • Sward, P.1    Rippe, B.2
  • 175
    • 84861850705 scopus 로고    scopus 로고
    • Matrix metalloproteinases in kidney homeostasis and diseases
    • Tan RJ, Liu Y. Matrix metalloproteinases in kidney homeostasis and diseases. Am J Physiol Renal Physiol 302:F1351-F1361, 2012.
    • (2012) Am J Physiol Renal Physiol , vol.302 , pp. F1351-F1361
    • Tan, R.J.1    Liu, Y.2
  • 177
    • 63449086757 scopus 로고    scopus 로고
    • Matrix metalloproteinases:Their potential role in the pathogenesis of diabetic nephropathy
    • Thrailkill KM, Clay Bunn R, Fowlkes JL. Matrix metalloproteinases:their potential role in the pathogenesis of diabetic nephropathy. Endocrine 35: 1-10, 2009.
    • (2009) Endocrine , vol.35 , pp. 1-10
    • Thrailkill, K.M.1    Clay Bunn, R.2    Fowlkes, J.L.3
  • 178
    • 0034858149 scopus 로고    scopus 로고
    • The human neutrophil lipocalin supports the allosteric activation of matrix metalloproteinases
    • Tschesche H, Zolzer V, Triebel S, Bartsch S. The human neutrophil lipocalin supports the allosteric activation of matrix metalloproteinases. Eur J Biochem 268: 1918-1928, 2001.
    • (2001) Eur J Biochem , vol.268 , pp. 1918-1928
    • Tschesche, H.1    Zolzer, V.2    Triebel, S.3    Bartsch, S.4
  • 180
    • 0642368050 scopus 로고    scopus 로고
    • BP180 (type XVII collagen) and its role in cutaneous biology and disease
    • Van den Bergh F, Giudice GJ. BP180 (type XVII collagen) and its role in cutaneous biology and disease. Adv Dermatol 19: 37-71, 2003.
    • (2003) Adv Dermatol , vol.19 , pp. 37-71
    • Van Den Bergh, F.1    Giudice, G.J.2
  • 184
    • 0015867765 scopus 로고
    • The origin, turnover and removal of glomerular basementmembrane
    • Walker F. The origin, turnover and removal of glomerular basementmembrane. J Pathol 110: 233-244, 1973.
    • (1973) J Pathol , vol.110 , pp. 233-244
    • Walker, F.1
  • 193
    • 65449170025 scopus 로고    scopus 로고
    • Rosiglitazone protects diabetic rats against kidney injury through the suppression of renal matrix metalloproteinase-9 expression
    • Yao XM, Ye SD, Chen Y, Zai ZM, Li XC, Wang YX, Chen K. Rosiglitazone protects diabetic rats against kidney injury through the suppression of renal matrix metalloproteinase-9 expression. Diabetes Obes Metab 11: 519-522, 2009.
    • (2009) Diabetes Obes Metab , vol.11 , pp. 519-522
    • Yao, X.M.1    Ye, S.D.2    Chen, Y.3    Zai, Z.M.4    Li, X.C.5    Wang, Y.X.6    Chen, K.7
  • 194
    • 77954195454 scopus 로고    scopus 로고
    • Simvastatin protects diabetic rats against kidney injury through the suppression of renal matrix metalloproteinase-9 expression
    • Yao XM, Ye SD, Zai Z, Chen Y, Li XC, Yang GW, Wang YX, Chen K. Simvastatin protects diabetic rats against kidney injury through the suppression of renal matrix metalloproteinase-9 expression. J Endocrinol Invest 33: 292-296, 2010.
    • (2010) J Endocrinol Invest , vol.33 , pp. 292-296
    • Yao, X.M.1    Ye, S.D.2    Zai, Z.3    Chen, Y.4    Li, X.C.5    Yang, G.W.6    Wang, Y.X.7    Chen, K.8
  • 195
    • 0031660652 scopus 로고    scopus 로고
    • Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration
    • Yauch RL, Berditchevski F, Harler MB, Reichner J, Hemler ME. Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration. Mol Biol Cell 9: 2751-2765, 1998.
    • (1998) Mol Biol Cell , vol.9 , pp. 2751-2765
    • Yauch, R.L.1    Berditchevski, F.2    Harler, M.B.3    Reichner, J.4    Hemler, M.E.5
  • 198
    • 38949151661 scopus 로고    scopus 로고
    • Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy
    • Ziyadeh FN, Wolf G. Pathogenesis of the podocytopathy and proteinuria in diabetic glomerulopathy. Curr Diabetes Rev 4: 39-45, 2008.
    • (2008) Curr Diabetes Rev , vol.4 , pp. 39-45
    • Ziyadeh, F.N.1    Wolf, G.2


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