Unilateral nephrectomy leads to up-regulation of syndecan-2- and TGF-beta-mediated glomerulosclerosis in syndecan-4 deficient male mice

Matrix Biology

Volumn 27, Issue 1, 2008, Pages 42-52

  Cevikbas, Ferda ^a   Schaefer, Liliana ^b   Uhlig, Philipp ^a   Robenek, Horst ^c   Theilmeier, Gregor ^a   Echtermeyer, Frank ^a   Bruckner, Peter ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Extracellular matrix; Fibrosis; Glomeruli; Kidney; Mesangium

Indexed keywords

CELL MEMBRANE PROTEIN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRONECTIN; MESSENGER RNA; PROTEOHEPARAN SULFATE; SYNDECAN 2; SYNDECAN 4; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE COURSE; EXTRACELLULAR MATRIX; FEMALE; FOCAL GLOMERULOSCLEROSIS; GLOMERULOSCLEROSIS; GLOMERULUS FILTRATION; IN VITRO STUDY; KIDNEY HYPERTROPHY; KIDNEY PARENCHYMA; KNOCKOUT MOUSE; MALE; MESANGIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UNINEPHRECTOMY; UPREGULATION;

ANIMALS; FEMALE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; IN SITU HYBRIDIZATION; KIDNEY; KIDNEY GLOMERULUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEPHRECTOMY; SYNDECAN-2; SYNDECAN-4; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

MUS;

EID: 38349151637     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2007.07.003     Document Type: Article

References (32)

1. Barratt J., and Feehally J. IgA nephropathy. J. Am. Soc. Nephrol. 16 (2005) 2088-2097
2. Bellin R., Capila I., Lincecum J., Park P.W., Reizes O., and Bernfield M.R. Unlocking the secrets of syndecans: transgenic organisms as a potential key. Glycoconj. J. 19 (2002) 295-304
3. Bottinger E.P., and Bitzer M. TGF-beta signaling in renal disease. J. Am. Soc. Nephrol. 13 (2002) 2600-2610
4. Chen L., Klass C., and Woods A. Syndecan-2 regulates transforming growth factor-β signaling. J. Biol. Chem. 279 (2004) 15715-15718
5. Chen Y., Lasaitiene D., Gabrielsson B.G., Carlsson L.M.S., Billig H., Carlsson B., Marcussen N., Sun X.-F., and Friberg P. Neonatal losartan treatment suppresses renal expression of molecules involved in cell-cell and cell-matrix interactions. J. Am. Soc. Nephrol. 15 (2004) 1232-1243
6. Chin B.Y., Mohsenin A., Li S.X., Choi A.M.K., and Choi M.E. Stimulation of pro-α1(I) collagen by TGF-β1 in mesangial cells: role of the p38 MAPK pathway. Am. J. Physiol. 280 (2001) F495-F504
7. Cizmeci-Smith G., Langan E., Youkey J., Showalter L.J., and Carey D.J. Syndecan-4 is a primary-response gene induced by basic fibroblast growth factor and arterial injury in vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 17 (1997) 172-180
8. David G., and Bernfield M. The emerging roles of cell surface heparan sulfate proteoglycans. Matrix Biol. 17 (1998) 461-463
9. David G., Bai X.M., Van der Schueren B., Marynen P., Cassiman J.J., and Van den Berghe H. Spatial and temporal changes in the expression of fibroglycan (syndecan-2) during mouse embryonic-development. Development 119 (1993) 841-854
10. Echtermeyer F., Streit M., Wilcox-Adelman S., Saoncella S., Denhez F., Detmar M., and Goetinck P. Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4. J. Clin. Invest. 107 (2001) R9-R14
11. Fleck C., Appenroth D., Jonas P., Koch M., Kundt G., Nizze H., and Stein G. Suitability of 5/6 nephrectomy (5/6NX) for the induction of interstitial renal fibrosis in rats - influence of sex, strain, and surgical procedure. Exp. Toxicol. Pathol. 57 (2006) 195-205
12. Floege J., and Feehally J. IgA nephropathy: recent developments. J. Am. Soc. Nephrol. 11 (2000) 2395-2403
13. Flyvbjerg A., Bennett W.F., Rasch R., Van Neck J.W., Groffen C.A.H., Kopchick J.J., and Scarlett J.A. Compensatory renal growth in uninephrectomized adult mice is growth hormone dependent. Kidney Int. 56 (1999) 2048-2054
14. Gagliardini E., and Benigni A. Role of anti-TGF-beta antibodies in the treatment of renal injury. Cytokine Growth Factor Rev. 17 (2006) 89-96
15. Gallo R.L., Ono M., Povsic T., Page C., Eriksson E., Klagsbrun M., and Bernfield M. Syndecans, cell surface heparan sulfate proteoglycans, and induced by a proline-rich antimicrobial peptide from wounds. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 11035-11039
16. Gressner A.M., and Weiskirchen R. Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets. J. Cell. Mol. Med. 10 (2006) 76-99
17. Hostetter T.H. Progression of renal disease and renal hypertrophy. Annu. Rev. Physiol. 57 (1995) 263-278
18. Hostetter T.H., Olson J.L., Rennke H.G., Venkatachalam M.A., and Brenner B.M. Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation. J. Am. Soc. Nephrol. 12 (2001) 1315-1325
19. Ishiguro K., Kadomatsu K., Kojima T., Muramatsu H., Tsuzuki S., Nakamura E., Kusugami K., Saito H., and Muramatsu T. Syndecan-4 deficiency impairs focal adhesion formation only under restricted conditions. J. Biol. Chem. 275 (2000) 5249-5252
20. Ishiguro K., Kadomatsu K., Kojima T., Muramatsu H., Matsuo S., Kusugami K., Saito H., and Muramatsu T. Syndecan-4 deficiency increases susceptibility to kappa-Carrageenan-induced renal damage. Lab. Invest. 81 (2001) 509-516
21. Kim C.W., Goldberger O.A., Gallo R.L., and Bernfield M. Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns. Mol. Biol. Cell 5 (1994) 797-805
22. Lovegrove A.S., Sun J., Gould K.A., Lubahn D.B., Korach K.S., and Lane P.H. Estrogen receptor α-mediated events promote sex-specific diabetic glomerular hypertrophy. Am. J. Physiol. 287 (2004) F586-F591
23. Mulroney S.E., and Pesce C. Early hyperplastic renal growth after uninephrectomy in adult female rats. Endocrinology 141 (2000) 932-937
24. Mulroney S.E., Lumpkin M.D., Roberts C.T., Leroith D., and Haramati A. Effect of a growth hormone-releasing factor antagonist on compensatory renal growth, insulin-like growth factor-I (IGF-I), and IGF-I receptor gene-expression after unilateral nephrectomy in immature rats. Endocrinology 130 (1992) 2697-2702
25. Mulroney S.E., Woda C., Johnson M., and Pesce C. Gender differences in renal growth and function after uninephrectomy in adult rats. Kidney Int. 56 (1999) 944-953
26. Pyke C., Kristensen P., Ostergaard P.B., Oturai P.S., and Romer J. Proteoglycan expression in the normal rat kidney. Nephron 77 (1997) 461-470
27. Schaefer L., Hausser H., Altenburger M., Ugorcakova J., August C., Fisher L.W., Schäfer R.M., and Kresse H. Decorin, biglycan and their endocytosis receptor in rat renal cortex. Kidney Int. 54 (1998) 1529-1541
28. Sheppard D. Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis. Proc. Am. Thorac. Soc. 3 (2006) 413-417
29. Sun J., Langer W.J., Devish K., and Lane P.H. Compensatory kidney growth in estrogen receptor-α null mice. Am. J. Physiol. 290 (2006) F319-F323
30. Woods A., and Couchman J.R. Syndecan-4 and focal adhesion function. Curr. Opin. Cell Biol. 13 (2001) 578-583
31. Yu L., Border W.A., Huang Y.F., and Noble N.A. TGF-beta isoforms in renal fibrogenesis. Kidney Int. 64 (2003) 844-856
32. Yung S., Woods A., Chan T.M., Davies M., Williams J.D., and Couchman J.R. Syndecan-4 up-regulation in proliferative renal disease is related to microfilament organization. FASEB J. 15 (2001) 1631-1633