-
1
-
-
42149122041
-
Properties of the glomerular barrier and mechanisms of proteinuria
-
Haraldsson B., Nystrom J., and Deen W.M. Properties of the glomerular barrier and mechanisms of proteinuria. Physiol. Rev. 88 (2008) 451-487
-
(2008)
Physiol. Rev.
, vol.88
, pp. 451-487
-
-
Haraldsson, B.1
Nystrom, J.2
Deen, W.M.3
-
2
-
-
67651089928
-
Glomerular filtration is normal in the absence of both agrin and perlecan-heparan sulfate from the glomerular basement membrane
-
Goldberg S., Harvey S.J., Cunningham J., Tryggvason K., and Miner J.H. Glomerular filtration is normal in the absence of both agrin and perlecan-heparan sulfate from the glomerular basement membrane. Nephrol. Dial. Transplant. 24 (2009) 2044-2051
-
(2009)
Nephrol. Dial. Transplant.
, vol.24
, pp. 2044-2051
-
-
Goldberg, S.1
Harvey, S.J.2
Cunningham, J.3
Tryggvason, K.4
Miner, J.H.5
-
3
-
-
34547680445
-
Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity
-
Harvey S.J., Jarad G., Cunningham J., Rops A.L., van der Vlag J., Berden J.H., Moeller M.J., Holzman L.B., Burgess R.W., and Miner J.H. Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity. Am. J. Pathol. 171 (2007) 139-152
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 139-152
-
-
Harvey, S.J.1
Jarad, G.2
Cunningham, J.3
Rops, A.L.4
van der Vlag, J.5
Berden, J.H.6
Moeller, M.J.7
Holzman, L.B.8
Burgess, R.W.9
Miner, J.H.10
-
4
-
-
70349330816
-
New insights into the role of podocytes in proteinuria
-
Patrakka J., and Tryggvason K. New insights into the role of podocytes in proteinuria. Nat. Rev. Nephrol. 5 (2009) 463-468
-
(2009)
Nat. Rev. Nephrol.
, vol.5
, pp. 463-468
-
-
Patrakka, J.1
Tryggvason, K.2
-
5
-
-
40849130173
-
VEGF inhibition and renal thrombotic microangiopathy
-
Eremina V., Jefferson J.A., Kowalewska J., Hochster H., Haas M., Weisstuch J., Richardson C., Kopp J.B., Kabir M.G., Backx P.H., Gerber H.P., Ferrara N., Barisoni L., Alpers C.E., and Quaggin S.E. VEGF inhibition and renal thrombotic microangiopathy. N. Engl. J. Med. 358 (2008) 1129-1136
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1129-1136
-
-
Eremina, V.1
Jefferson, J.A.2
Kowalewska, J.3
Hochster, H.4
Haas, M.5
Weisstuch, J.6
Richardson, C.7
Kopp, J.B.8
Kabir, M.G.9
Backx, P.H.10
Gerber, H.P.11
Ferrara, N.12
Barisoni, L.13
Alpers, C.E.14
Quaggin, S.E.15
-
6
-
-
0037370325
-
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
-
Eremina V., Sood M., Haigh J., Nagy A., Lajoie G., Ferrara N., Gerber H.P., Kikkawa Y., Miner J.H., and Quaggin S.E. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J. Clin. Invest. 111 (2003) 707-716
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 707-716
-
-
Eremina, V.1
Sood, M.2
Haigh, J.3
Nagy, A.4
Lajoie, G.5
Ferrara, N.6
Gerber, H.P.7
Kikkawa, Y.8
Miner, J.H.9
Quaggin, S.E.10
-
7
-
-
0038469583
-
Alport's syndrome, Goodpasture's syndrome, and type IV collagen
-
Hudson B.G., Tryggvason K., Sundaramoorthy M., and Neilson E.G. Alport's syndrome, Goodpasture's syndrome, and type IV collagen. N. Engl. J. Med. 348 (2003) 2543-2556
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 2543-2556
-
-
Hudson, B.G.1
Tryggvason, K.2
Sundaramoorthy, M.3
Neilson, E.G.4
-
8
-
-
0029127384
-
The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1
-
Noakes P.G., Miner J.H., Gautam M., Cunningham J.M., Sanes J.R., and Merlie J.P. The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1. Nat. Genet. 10 (1995) 400-406
-
(1995)
Nat. Genet.
, vol.10
, pp. 400-406
-
-
Noakes, P.G.1
Miner, J.H.2
Gautam, M.3
Cunningham, J.M.4
Sanes, J.R.5
Merlie, J.P.6
-
9
-
-
8444221929
-
Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities
-
Zenker M., Aigner T., Wendler O., Tralau T., Muntefering H., Fenski R., Pitz S., Schumacher V., Royer-Pokora B., Wuhl E., Cochat P., Bouvier R., Kraus C., Mark K., Madlon H., Dotsch J., Rascher W., Maruniak-Chudek I., Lennert T., Neumann L.M., and Reis A. Human laminin beta2 deficiency causes congenital nephrosis with mesangial sclerosis and distinct eye abnormalities. Hum. Mol. Genet. 13 (2004) 2625-2632
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2625-2632
-
-
Zenker, M.1
Aigner, T.2
Wendler, O.3
Tralau, T.4
Muntefering, H.5
Fenski, R.6
Pitz, S.7
Schumacher, V.8
Royer-Pokora, B.9
Wuhl, E.10
Cochat, P.11
Bouvier, R.12
Kraus, C.13
Mark, K.14
Madlon, H.15
Dotsch, J.16
Rascher, W.17
Maruniak-Chudek, I.18
Lennert, T.19
Neumann, L.M.20
Reis, A.21
more..
-
10
-
-
33746730496
-
Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier
-
Jarad G., Cunningham J., Shaw A.S., and Miner J.H. Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier. J. Clin. Invest. 116 (2006) 2272-2279
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2272-2279
-
-
Jarad, G.1
Cunningham, J.2
Shaw, A.S.3
Miner, J.H.4
-
11
-
-
5744238949
-
Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line
-
Utriainen A., Sormunen R., Kettunen M., Carvalhaes L.S., Sajanti E., Eklund L., Kauppinen R., Kitten G.T., and Pihlajaniemi T. Structurally altered basement membranes and hydrocephalus in a type XVIII collagen deficient mouse line. Hum. Mol. Genet. 13 (2004) 2089-2099
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 2089-2099
-
-
Utriainen, A.1
Sormunen, R.2
Kettunen, M.3
Carvalhaes, L.S.4
Sajanti, E.5
Eklund, L.6
Kauppinen, R.7
Kitten, G.T.8
Pihlajaniemi, T.9
-
12
-
-
0019304713
-
Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion
-
Kanwar Y.S., Linker A., and Farquhar M.G. Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion. J. Cell Biol. 86 (1980) 688-693
-
(1980)
J. Cell Biol.
, vol.86
, pp. 688-693
-
-
Kanwar, Y.S.1
Linker, A.2
Farquhar, M.G.3
-
13
-
-
34848907421
-
Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton
-
Faul C., Asanuma K., Yanagida-Asanuma E., Kim K., and Mundel P. Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton. Trends Cell Biol. 17 (2007) 428-437
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 428-437
-
-
Faul, C.1
Asanuma, K.2
Yanagida-Asanuma, E.3
Kim, K.4
Mundel, P.5
-
14
-
-
0029855437
-
Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis
-
Kreidberg J.A., Donovan M.J., Goldstein S.L., Rennke H., Shepherd K., Jones R.C., and Jaenisch R. Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis. Development 122 (1996) 3537-3547
-
(1996)
Development
, vol.122
, pp. 3537-3547
-
-
Kreidberg, J.A.1
Donovan, M.J.2
Goldstein, S.L.3
Rennke, H.4
Shepherd, K.5
Jones, R.C.6
Jaenisch, R.7
-
15
-
-
33749551723
-
Kidney failure in mice lacking the tetraspanin CD151
-
Sachs N., Kreft M., van den Bergh Weerman M.A., Beynon A.J., Peters T.A., Weening J.J., and Sonnenberg A. Kidney failure in mice lacking the tetraspanin CD151. J. Cell Biol. 175 (2006) 33-39
-
(2006)
J. Cell Biol.
, vol.175
, pp. 33-39
-
-
Sachs, N.1
Kreft, M.2
van den Bergh Weerman, M.A.3
Beynon, A.J.4
Peters, T.A.5
Weening, J.J.6
Sonnenberg, A.7
-
16
-
-
41149083878
-
Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity
-
Pozzi A., Jarad G., Moeckel G.W., Coffa S., Zhang X., Gewin L., Eremina V., Hudson B.G., Borza D.B., Harris R.C., Holzman L.B., Phillips C.L., Fassler R., Quaggin S.E., Miner J.H., and Zent R. Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity. Dev. Biol. 316 (2008) 288-301
-
(2008)
Dev. Biol.
, vol.316
, pp. 288-301
-
-
Pozzi, A.1
Jarad, G.2
Moeckel, G.W.3
Coffa, S.4
Zhang, X.5
Gewin, L.6
Eremina, V.7
Hudson, B.G.8
Borza, D.B.9
Harris, R.C.10
Holzman, L.B.11
Phillips, C.L.12
Fassler, R.13
Quaggin, S.E.14
Miner, J.H.15
Zent, R.16
-
17
-
-
37849026460
-
Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus
-
Kanasaki K., Kanda Y., Palmsten K., Tanjore H., Lee S.B., Lebleu V.S., Gattone Jr. V.H., and Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev. Biol. 313 (2008) 584-593
-
(2008)
Dev. Biol.
, vol.313
, pp. 584-593
-
-
Kanasaki, K.1
Kanda, Y.2
Palmsten, K.3
Tanjore, H.4
Lee, S.B.5
Lebleu, V.S.6
Gattone Jr., V.H.7
Kalluri, R.8
-
18
-
-
17144464384
-
Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells
-
Doi M., Thyboll J., Kortesmaa J., Jansson K., Iivanainen A., Parvardeh M., Timpl R., Hedin U., Swedenborg J., and Tryggvason K. Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells. J. Biol. Chem. 277 (2002) 12741-12748
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12741-12748
-
-
Doi, M.1
Thyboll, J.2
Kortesmaa, J.3
Jansson, K.4
Iivanainen, A.5
Parvardeh, M.6
Timpl, R.7
Hedin, U.8
Swedenborg, J.9
Tryggvason, K.10
-
19
-
-
33646356720
-
Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis
-
El-Aouni C., Herbach N., Blattner S.M., Henger A., Rastaldi M.P., Jarad G., Miner J.H., Moeller M.J., St-Arnaud R., Dedhar S., Holzman L.B., Wanke R., and Kretzler M. Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis. J. Am. Soc. Nephrol. 17 (2006) 1334-1344
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 1334-1344
-
-
El-Aouni, C.1
Herbach, N.2
Blattner, S.M.3
Henger, A.4
Rastaldi, M.P.5
Jarad, G.6
Miner, J.H.7
Moeller, M.J.8
St-Arnaud, R.9
Dedhar, S.10
Holzman, L.B.11
Wanke, R.12
Kretzler, M.13
-
20
-
-
33746491157
-
Essential role of integrin-linked kinase in podocyte biology: bridging the integrin and slit diaphragm signaling
-
Dai C., Stolz D.B., Bastacky S.I., St-Arnaud R., Wu C., Dedhar S., and Liu Y. Essential role of integrin-linked kinase in podocyte biology: bridging the integrin and slit diaphragm signaling. J. Am. Soc. Nephrol. 17 (2006) 2164-2175
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 2164-2175
-
-
Dai, C.1
Stolz, D.B.2
Bastacky, S.I.3
St-Arnaud, R.4
Wu, C.5
Dedhar, S.6
Liu, Y.7
-
21
-
-
0034009952
-
Glomerular expression of dystroglycans is reduced in minimal change nephrosis but not in focal segmental glomerulosclerosis
-
Regele H.M., Fillipovic E., Langer B., Poczewki H., Kraxberger I., Bittner R.E., and Kerjaschki D. Glomerular expression of dystroglycans is reduced in minimal change nephrosis but not in focal segmental glomerulosclerosis. J. Am. Soc. Nephrol. 11 (2000) 403-412
-
(2000)
J. Am. Soc. Nephrol.
, vol.11
, pp. 403-412
-
-
Regele, H.M.1
Fillipovic, E.2
Langer, B.3
Poczewki, H.4
Kraxberger, I.5
Bittner, R.E.6
Kerjaschki, D.7
-
22
-
-
38049032013
-
Modification of kidney barrier function by the urokinase receptor
-
Wei C., Moller C.C., Altintas M.M., Li J., Schwarz K., Zacchigna S., Xie L., Henger A., Schmid H., Rastaldi M.P., Cowan P., Kretzler M., Parrilla R., Bendayan M., Gupta V., Nikolic B., Kalluri R., Carmeliet P., Mundel P., and Reiser J. Modification of kidney barrier function by the urokinase receptor. Nat. Med. 14 (2008) 55-63
-
(2008)
Nat. Med.
, vol.14
, pp. 55-63
-
-
Wei, C.1
Moller, C.C.2
Altintas, M.M.3
Li, J.4
Schwarz, K.5
Zacchigna, S.6
Xie, L.7
Henger, A.8
Schmid, H.9
Rastaldi, M.P.10
Cowan, P.11
Kretzler, M.12
Parrilla, R.13
Bendayan, M.14
Gupta, V.15
Nikolic, B.16
Kalluri, R.17
Carmeliet, P.18
Mundel, P.19
Reiser, J.20
more..
-
23
-
-
0015953201
-
Porous substructure of the glomerular slit diaphragm in the rat and mouse
-
Rodewald R., and Karnovsky M.J. Porous substructure of the glomerular slit diaphragm in the rat and mouse. J. Cell Biol. 60 (1974) 423-433
-
(1974)
J. Cell Biol.
, vol.60
, pp. 423-433
-
-
Rodewald, R.1
Karnovsky, M.J.2
-
24
-
-
22244466451
-
Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex
-
Lehtonen S., Ryan J.J., Kudlicka K., Iino N., Zhou H., and Farquhar M.G. Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex. Proc. Natl. Acad. Sci. USA 102 (2005) 9814-9819
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9814-9819
-
-
Lehtonen, S.1
Ryan, J.J.2
Kudlicka, K.3
Iino, N.4
Zhou, H.5
Farquhar, M.G.6
-
25
-
-
34548526982
-
Nephrin-a unique structural and signaling protein of the kidney filter
-
Patrakka J., and Tryggvason K. Nephrin-a unique structural and signaling protein of the kidney filter. Trends Mol. Med. 13 (2007) 396-403
-
(2007)
Trends Mol. Med.
, vol.13
, pp. 396-403
-
-
Patrakka, J.1
Tryggvason, K.2
-
26
-
-
0032015551
-
Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome
-
Kestila M., Lenkkeri U., Mannikko M., Lamerdin J., McCready P., Putaala H., Ruotsalainen V., Morita T., Nissinen M., Herva R., Kashtan C.E., Peltonen L., Holmberg C., Olsen A., and Tryggvason K. Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome. Mol. Cell 1 (1998) 575-582
-
(1998)
Mol. Cell
, vol.1
, pp. 575-582
-
-
Kestila, M.1
Lenkkeri, U.2
Mannikko, M.3
Lamerdin, J.4
McCready, P.5
Putaala, H.6
Ruotsalainen, V.7
Morita, T.8
Nissinen, M.9
Herva, R.10
Kashtan, C.E.11
Peltonen, L.12
Holmberg, C.13
Olsen, A.14
Tryggvason, K.15
-
27
-
-
33645749205
-
Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography
-
Wartiovaara J., Ofverstedt L.G., Khoshnoodi J., Zhang J., Makela E., Sandin S., Ruotsalainen V., Cheng R.H., Jalanko H., Skoglund U., and Tryggvason K. Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography. J. Clin. Invest. 114 (2004) 1475-1483
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1475-1483
-
-
Wartiovaara, J.1
Ofverstedt, L.G.2
Khoshnoodi, J.3
Zhang, J.4
Makela, E.5
Sandin, S.6
Ruotsalainen, V.7
Cheng, R.H.8
Jalanko, H.9
Skoglund, U.10
Tryggvason, K.11
-
28
-
-
33646401549
-
Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
-
Verma R., Kovari I., Soofi A., Nihalani D., Patrie K., and Holzman L.B. Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J. Clin. Invest. 116 (2006) 1346-1359
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1346-1359
-
-
Verma, R.1
Kovari, I.2
Soofi, A.3
Nihalani, D.4
Patrie, K.5
Holzman, L.B.6
-
29
-
-
33645746950
-
Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes
-
Jones N., Blasutig I.M., Eremina V., Ruston J.M., Bladt F., Li H., Huang H., Larose L., Li S.S., Takano T., Quaggin S.E., and Pawson T. Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature 440 (2006) 818-823
-
(2006)
Nature
, vol.440
, pp. 818-823
-
-
Jones, N.1
Blasutig, I.M.2
Eremina, V.3
Ruston, J.M.4
Bladt, F.5
Li, H.6
Huang, H.7
Larose, L.8
Li, S.S.9
Takano, T.10
Quaggin, S.E.11
Pawson, T.12
-
30
-
-
0033536599
-
Congenital nephrotic syndrome in mice lacking CD2-associated protein
-
Shih N.Y., Li J., Karpitskii V., Nguyen A., Dustin M.L., Kanagawa O., Miner J.H., and Shaw A.S. Congenital nephrotic syndrome in mice lacking CD2-associated protein. Science 286 (1999) 312-315
-
(1999)
Science
, vol.286
, pp. 312-315
-
-
Shih, N.Y.1
Li, J.2
Karpitskii, V.3
Nguyen, A.4
Dustin, M.L.5
Kanagawa, O.6
Miner, J.H.7
Shaw, A.S.8
-
31
-
-
67649690129
-
Nck proteins maintain the adult glomerular filtration barrier
-
Jones N., New L.A., Fortino M.A., Eremina V., Ruston J., Blasutig I.M., Aoudjit L., Zou Y., Liu X., Yu G.L., Takano T., Quaggin S.E., and Pawson T. Nck proteins maintain the adult glomerular filtration barrier. J. Am. Soc. Nephrol. 20 (2009) 1533-1543
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 1533-1543
-
-
Jones, N.1
New, L.A.2
Fortino, M.A.3
Eremina, V.4
Ruston, J.5
Blasutig, I.M.6
Aoudjit, L.7
Zou, Y.8
Liu, X.9
Yu, G.L.10
Takano, T.11
Quaggin, S.E.12
Pawson, T.13
-
32
-
-
37549036286
-
Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization
-
Garg P., Verma R., Nihalani D., Johnstone D.B., and Holzman L.B. Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization. Mol. Cell Biol. 27 (2007) 8698-8712
-
(2007)
Mol. Cell Biol.
, vol.27
, pp. 8698-8712
-
-
Garg, P.1
Verma, R.2
Nihalani, D.3
Johnstone, D.B.4
Holzman, L.B.5
-
33
-
-
0034948819
-
Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN
-
Donoviel D.B., Freed D.D., Vogel H., Potter D.G., Hawkins E., Barrish J.P., Mathur B.N., Turner C.A., Geske R., Montgomery C.A., Starbuck M., Brandt M., Gupta A., Ramirez-Solis R., Zambrowicz B.P., and Powell D.R. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol. Cell. Biol. 21 (2001) 4829-4836
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4829-4836
-
-
Donoviel, D.B.1
Freed, D.D.2
Vogel, H.3
Potter, D.G.4
Hawkins, E.5
Barrish, J.P.6
Mathur, B.N.7
Turner, C.A.8
Geske, R.9
Montgomery, C.A.10
Starbuck, M.11
Brandt, M.12
Gupta, A.13
Ramirez-Solis, R.14
Zambrowicz, B.P.15
Powell, D.R.16
-
34
-
-
0034034757
-
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome
-
Boute N., Gribouval O., Roselli S., Benessy F., Lee H., Fuchshuber A., Dahan K., Gubler M.C., Niaudet P., and Antignac C. NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome. Nat. Genet. 24 (2000) 349-354
-
(2000)
Nat. Genet.
, vol.24
, pp. 349-354
-
-
Boute, N.1
Gribouval, O.2
Roselli, S.3
Benessy, F.4
Lee, H.5
Fuchshuber, A.6
Dahan, K.7
Gubler, M.C.8
Niaudet, P.9
Antignac, C.10
-
35
-
-
0037270882
-
NEPH1 defines a novel family of podocin interacting proteins
-
Sellin L., Huber T.B., Gerke P., Quack I., Pavenstadt H., and Walz G. NEPH1 defines a novel family of podocin interacting proteins. FASEB J. 17 (2003) 115-117
-
(2003)
FASEB J.
, vol.17
, pp. 115-117
-
-
Sellin, L.1
Huber, T.B.2
Gerke, P.3
Quack, I.4
Pavenstadt, H.5
Walz, G.6
-
36
-
-
0035210324
-
Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin
-
Schwarz K., Simons M., Reiser J., Saleem M.A., Faul C., Kriz W., Shaw A.S., Holzman L.B., and Mundel P. Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin. J. Clin. Invest. 108 (2001) 1621-1629
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1621-1629
-
-
Schwarz, K.1
Simons, M.2
Reiser, J.3
Saleem, M.A.4
Faul, C.5
Kriz, W.6
Shaw, A.S.7
Holzman, L.B.8
Mundel, P.9
-
37
-
-
0347986678
-
Early glomerular filtration defect and severe renal disease in podocin-deficient mice
-
Roselli S., Heidet L., Sich M., Henger A., Kretzler M., Gubler M.C., and Antignac C. Early glomerular filtration defect and severe renal disease in podocin-deficient mice. Mol. Cell. Biol. 24 (2004) 550-560
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 550-560
-
-
Roselli, S.1
Heidet, L.2
Sich, M.3
Henger, A.4
Kretzler, M.5
Gubler, M.C.6
Antignac, C.7
-
38
-
-
22844436647
-
TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function
-
Reiser J., Polu K.R., Moller C.C., Kenlan P., Altintas M.M., Wei C., Faul C., Herbert S., Villegas I., Avila-Casado C., McGee M., Sugimoto H., Brown D., Kalluri R., Mundel P., Smith P.L., Clapham D.E., and Pollak M.R. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat. Genet. 37 (2005) 739-744
-
(2005)
Nat. Genet.
, vol.37
, pp. 739-744
-
-
Reiser, J.1
Polu, K.R.2
Moller, C.C.3
Kenlan, P.4
Altintas, M.M.5
Wei, C.6
Faul, C.7
Herbert, S.8
Villegas, I.9
Avila-Casado, C.10
McGee, M.11
Sugimoto, H.12
Brown, D.13
Kalluri, R.14
Mundel, P.15
Smith, P.L.16
Clapham, D.E.17
Pollak, M.R.18
-
39
-
-
20844461826
-
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis
-
Winn M.P., Conlon P.J., Lynn K.L., Farrington M.K., Creazzo T., Hawkins A.F., Daskalakis N., Kwan S.Y., Ebersviller S., Burchette J.L., Pericak-Vance M.A., Howell D.N., Vance J.M., and Rosenberg P.B. A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. Science 308 (2005) 1801-1804
-
(2005)
Science
, vol.308
, pp. 1801-1804
-
-
Winn, M.P.1
Conlon, P.J.2
Lynn, K.L.3
Farrington, M.K.4
Creazzo, T.5
Hawkins, A.F.6
Daskalakis, N.7
Kwan, S.Y.8
Ebersviller, S.9
Burchette, J.L.10
Pericak-Vance, M.A.11
Howell, D.N.12
Vance, J.M.13
Rosenberg, P.B.14
-
40
-
-
0038641811
-
Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype
-
Ciani L., Patel A., Allen N.D., and ffrench-Constant C. Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype. Mol. Cell. Biol. 23 (2003) 3575-3582
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 3575-3582
-
-
Ciani, L.1
Patel, A.2
Allen, N.D.3
ffrench-Constant, C.4
-
42
-
-
33947232065
-
Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, Ehd3, Sh2d4a, Plekhh2, and 2310066E14Rik
-
Patrakka J., Xiao Z., Nukui M., Takemoto M., He L., Oddsson A., Perisic L., Kaukinen A., Al-Khaliliszigyarto C., Uhlen M., Jalanko H., Betsholtz C., and Tryggvason K. Expression and subcellular distribution of novel glomerulus-associated proteins dendrin, Ehd3, Sh2d4a, Plekhh2, and 2310066E14Rik. J. Am. Soc. Nephrol. 18 (2007) 689-697
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 689-697
-
-
Patrakka, J.1
Xiao, Z.2
Nukui, M.3
Takemoto, M.4
He, L.5
Oddsson, A.6
Perisic, L.7
Kaukinen, A.8
Al-Khaliliszigyarto, C.9
Uhlen, M.10
Jalanko, H.11
Betsholtz, C.12
Tryggvason, K.13
-
43
-
-
34547213485
-
Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes
-
Asanuma K., Campbell K.N., Kim K., Faul C., and Mundel P. Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes. Proc. Natl. Acad. Sci. USA 104 (2007) 10134-10139
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 10134-10139
-
-
Asanuma, K.1
Campbell, K.N.2
Kim, K.3
Faul, C.4
Mundel, P.5
-
44
-
-
33645403170
-
Hereditary proteinuria syndromes and mechanisms of proteinuria
-
Tryggvason K., Patrakka J., and Wartiovaara J. Hereditary proteinuria syndromes and mechanisms of proteinuria. N. Engl. J. Med. 354 (2006) 1387-1401
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1387-1401
-
-
Tryggvason, K.1
Patrakka, J.2
Wartiovaara, J.3
-
45
-
-
68049146008
-
The role of podocalyxin in health and disease
-
Nielsen J.S., and McNagny K.M. The role of podocalyxin in health and disease. J. Am. Soc. Nephrol. 20 (2009) 1669-1676
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 1669-1676
-
-
Nielsen, J.S.1
McNagny, K.M.2
-
46
-
-
0035796487
-
Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin
-
Doyonnas R., Kershaw D.B., Duhme C., Merkens H., Chelliah S., Graf T., and McNagny K.M. Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin. J. Exp. Med. 194 (2001) 13-27
-
(2001)
J. Exp. Med.
, vol.194
, pp. 13-27
-
-
Doyonnas, R.1
Kershaw, D.B.2
Duhme, C.3
Merkens, H.4
Chelliah, S.5
Graf, T.6
McNagny, K.M.7
-
47
-
-
0034954343
-
Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton
-
Takeda T., McQuistan T., Orlando R.A., and Farquhar M.G. Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton. J. Clin. Invest. 108 (2001) 289-301
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 289-301
-
-
Takeda, T.1
McQuistan, T.2
Orlando, R.A.3
Farquhar, M.G.4
-
48
-
-
0028167598
-
GLEPP1, a renal glomerular epithelial cell (podocyte) membrane protein-tyrosine phosphatase. Identification, molecular cloning, and characterization in rabbit
-
Thomas P.E., Wharram B.L., Goyal M., Wiggins J.E., Holzman L.B., and Wiggins R.C. GLEPP1, a renal glomerular epithelial cell (podocyte) membrane protein-tyrosine phosphatase. Identification, molecular cloning, and characterization in rabbit. J. Biol. Chem. 269 (1994) 19953-19962
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 19953-19962
-
-
Thomas, P.E.1
Wharram, B.L.2
Goyal, M.3
Wiggins, J.E.4
Holzman, L.B.5
Wiggins, R.C.6
-
49
-
-
0033722475
-
Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate
-
Wharram B.L., Goyal M., Gillespie P.J., Wiggins J.E., Kershaw D.B., Holzman L.B., Dysko R.C., Saunders T.L., Samuelson L.C., and Wiggins R.C. Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate. J. Clin. Invest. 106 (2000) 1281-1290
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1281-1290
-
-
Wharram, B.L.1
Goyal, M.2
Gillespie, P.J.3
Wiggins, J.E.4
Kershaw, D.B.5
Holzman, L.B.6
Dysko, R.C.7
Saunders, T.L.8
Samuelson, L.C.9
Wiggins, R.C.10
-
50
-
-
0034051681
-
Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis
-
Kaplan J.M., Kim S.H., North K.N., Rennke H., Correia L.A., Tong H.Q., Mathis B.J., Rodriguez-Perez J.C., Allen P.G., Beggs A.H., and Pollak M.R. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis. Nat. Genet. 24 (2000) 251-256
-
(2000)
Nat. Genet.
, vol.24
, pp. 251-256
-
-
Kaplan, J.M.1
Kim, S.H.2
North, K.N.3
Rennke, H.4
Correia, L.A.5
Tong, H.Q.6
Mathis, B.J.7
Rodriguez-Perez, J.C.8
Allen, P.G.9
Beggs, A.H.10
Pollak, M.R.11
-
51
-
-
0037407791
-
Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4
-
Michaud J.L., Lemieux L.I., Dube M., Vanderhyden B.C., Robertson S.J., and Kennedy C.R. Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4. J. Am. Soc. Nephrol. 14 (2003) 1200-1211
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 1200-1211
-
-
Michaud, J.L.1
Lemieux, L.I.2
Dube, M.3
Vanderhyden, B.C.4
Robertson, S.J.5
Kennedy, C.R.6
-
52
-
-
36049021909
-
Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity
-
Weins A., Schlondorff J.S., Nakamura F., Denker B.M., Hartwig J.H., Stossel T.P., and Pollak M.R. Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity. Proc. Natl. Acad. Sci. USA 104 (2007) 16080-16085
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16080-16085
-
-
Weins, A.1
Schlondorff, J.S.2
Nakamura, F.3
Denker, B.M.4
Hartwig, J.H.5
Stossel, T.P.6
Pollak, M.R.7
-
53
-
-
33847001656
-
Alpha-actinin-4 is required for normal podocyte adhesion
-
Dandapani S.V., Sugimoto H., Matthews B.D., Kolb R.J., Sinha S., Gerszten R.E., Zhou J., Ingber D.E., Kalluri R., and Pollak M.R. Alpha-actinin-4 is required for normal podocyte adhesion. J. Biol. Chem. 282 (2007) 467-477
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 467-477
-
-
Dandapani, S.V.1
Sugimoto, H.2
Matthews, B.D.3
Kolb, R.J.4
Sinha, S.5
Gerszten, R.E.6
Zhou, J.7
Ingber, D.E.8
Kalluri, R.9
Pollak, M.R.10
-
54
-
-
18244384042
-
Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner
-
Asanuma K., Kim K., Oh J., Giardino L., Chabanis S., Faul C., Reiser J., and Mundel P. Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. J. Clin. Invest. 115 (2005) 1188-1198
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1188-1198
-
-
Asanuma, K.1
Kim, K.2
Oh, J.3
Giardino, L.4
Chabanis, S.5
Faul, C.6
Reiser, J.7
Mundel, P.8
-
55
-
-
51349162919
-
The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A
-
Faul C., Donnelly M., Merscher-Gomez S., Chang Y.H., Franz S., Delfgaauw J., Chang J.M., Choi H.Y., Campbell K.N., Kim K., Reiser J., and Mundel P. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat. Med. 14 (2008) 931-938
-
(2008)
Nat. Med.
, vol.14
, pp. 931-938
-
-
Faul, C.1
Donnelly, M.2
Merscher-Gomez, S.3
Chang, Y.H.4
Franz, S.5
Delfgaauw, J.6
Chang, J.M.7
Choi, H.Y.8
Campbell, K.N.9
Kim, K.10
Reiser, J.11
Mundel, P.12
-
56
-
-
33644863418
-
Large-scale identification of genes implicated in kidney glomerulus development and function
-
Takemoto M., He L., Norlin J., Patrakka J., Xiao Z., Petrova T., Bondjers C., Asp J., Wallgard E., Sun Y., Samuelsson T., Mostad P., Lundin S., Miura N., Sado Y., Alitalo K., Quaggin S.E., Tryggvason K., and Betsholtz C. Large-scale identification of genes implicated in kidney glomerulus development and function. EMBO J. 25 (2006) 1160-1174
-
(2006)
EMBO J.
, vol.25
, pp. 1160-1174
-
-
Takemoto, M.1
He, L.2
Norlin, J.3
Patrakka, J.4
Xiao, Z.5
Petrova, T.6
Bondjers, C.7
Asp, J.8
Wallgard, E.9
Sun, Y.10
Samuelsson, T.11
Mostad, P.12
Lundin, S.13
Miura, N.14
Sado, Y.15
Alitalo, K.16
Quaggin, S.E.17
Tryggvason, K.18
Betsholtz, C.19
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