The human neutrophil lipocalin supports the allosteric activation of matrix metalloproteinases

European Journal of Biochemistry

Volumn 268, Issue 7, 2001, Pages 1918-1928

  Tschesche, Harald ^a   Zölzer, Volker ^a   Triebel, Susanne ^a   Bartsch, Stefan ^a  

^a BIELEFELD UNIVERSITY   (Germany)

Author keywords

Activation; Human leukocytes; Lipocalin; Matrix metalloproteinases; Pichia pastoris

Indexed keywords

ENZYME PRECURSOR; GELATINASE B; LIPOCALIN; MATRIX METALLOPROTEINASE; MERCURY CHLORIDE; NEUTROPHIL COLLAGENASE; PLASMA KALLIKREIN; TRYPSIN;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME ISOLATION; ENZYME PURIFICATION; ESCHERICHIA COLI; GRANULOCYTE; LIGAND BINDING; NEUTROPHIL; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACUTE-PHASE PROTEINS; AMINO ACID SEQUENCE; CARRIER PROTEINS; COLLAGENASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ENZYME PRECURSORS; ESCHERICHIA COLI; HUMANS; KALLIKREINS; KINETICS; MATRIX METALLOPROTEINASE 8; MATRIX METALLOPROTEINASE 9; MERCURIC CHLORIDE; MOLECULAR SEQUENCE DATA; NEUTROPHILS; ONCOGENE PROTEINS; PICHIA; PROTO-ONCOGENE PROTEINS;

EID: 0034858149     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02066.x     Document Type: Article

References (44)

1. Homology of β-lactoglobulin, serum retinol-binding protein and protein HC
2. Structure and sequence relationships in the lipocalins and related proteins
3. Functional expression of the uncomplexed serum retinol-binding protein in Escherichia coli. Ligand binding and reversible unfolding characteristics
4. The lipocalin protein family: A role in cell regulation
5. Three odorant-binding proteins from rabbit nasal mucosa
6. Accumulation of apolipoproteins in the regenerating and remyelating mammalian peripheral nerve. Identification of apolipoprotein D, apolipoprotein A-IV, apolipoprotein E, and apolipoprotein A-I
7. Possible pheromone-carrier function of two lipocalin proteins in the vomeronasal organ
8. cDNA sequence and expression pattern of the putative pheromone carrier aphrodisin
9. Arachidonic acid binds to apolipoprotein D: Implications for the protein's function
10. Retinoic acid-induced expression of apolipoprotein D and concomitant growth arrest in human breast cancer cells are mediated through a retinoic acid receptor RARalpha-dependent signaling pathway
11. Isolation of an adhesion-mediating protein from chick neural retina adherons
12. A chick neural retina adhesion and survival molecule is a retinol-binding protein
13. The crystal structure of nitrophorin 4 at 1.5 Å resolution: Transport of nitric oxide by a lipocalin-based heme protein
14. Purification and characterization of rat brain prostaglandin D synthetase
15. A 25 kDa α-2-microglobulin-related protein is a component of the 125 kDa form of human gelatinase
16. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase
17. The monitoring of inflammation by specific cellular markers
18. The development of an assay for human neutrophil lipocalin (HNL) to be used as a specific marker of neutrophil activity in vivo and vitro
19. Serum measurements of human neutrophil lipocalin (HNL) discriminate between acute bacterial and viral infections
20. Leukocyte activation detected by increased plasma levels of inflammatory mediators in patients with ischemic cerebrovascular diseases
21. Leukocyte activation in atherosclerosis: Correlation with risk factors
22. Human neutrophil lipocalin (HNL) is a specific granule constituent of the neutrophil granulocyte. Studies in bronchial and lung parenchymal tissue and peripheral blood cells
23. Subcellular localization and translocation of the receptor for N-formylmethionyl-leucyl-phenylalanine in human neutrophils
24. Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases
25. Latent collagenase and gelatinase from human neutrophils and their activation
26. Cloning and expression of human neutrophil lipocalin cDNA derived from bone marrow and ovarian cancer cells
27. A sandwich enzyme immunoassay for the determination of neutrophil lipocalin in body fluids
28. Synthetic substrates for vertebrate collagenase
29. A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases
30. The reliability of molecular weight determination by sulfate-polyacrylamide gel electrophoresis
31. Mercurial activation of human PMN leukocyte type IV procollagenase (gelatinase)
32. Mercurial activation of human polymorphonuclear leucocyte procollagenase
33. Structural and functional heterogeneity among peroxidase-negative granules in human neutrophils: Identification of a distinct gelatinase-containing granule subset by combined immunocyto-chemistry and subcellular fractionation
34. Molecular cloning and expression of a cDNA encoding NGAL: A lipocalin expressed in human neutrophils
35. Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carrier proteins
36. Structural and functional significance of cysteine residues of glutathione-independent prostaglandin D synthase. Identification of Cys65 as an essential thiol
37. Glutathione-independent prostaglandin D synthase as a lead molecule for designing new functional proteins
38. Xanthophyll cycle enzymes are members of the lipocalin family, the first identified from plants
39. 73 active-site zinc complex in latency and a 'cysteine switch' mechanism for activation
40. The cysteine switch: A principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family
41. Proteolytic and non-proteolytic activation of human neutrophil progelatinase B
42. The solution structure and dynamics of human neutrophil gelatinase-associated lipocalin
43. Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin