Antioxidant and hepatoprotective effect of polyphenols from apple pomace extract via apoptosis inhibition and Nrf2 activation in mice

Human and Experimental Toxicology

Volumn 35, Issue 12, 2016, Pages 1264-1275

  Sharma, S ^a,b   Rana, S ^b,c   Patial, V ^a,b   Gupta, M ^b,d   Bhushan, S ^b,c   Padwad, Y S ^a,b  

^a CSIR INSTITUTE OF HIMALAYAN BIORESOURCE TECHNOLOGY   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

^c I H B T (CSIR)   (India)

^d Food and Nutraceutical Laboratory   (India)

Author keywords

apoptosis; Apple pomace; CCl4; hepatoprotective; Nrf2

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTIOXIDANT; APPLE POMACE EXTRACT; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; FLAVONOID; GLUTATHIONE; LIVER PROTECTIVE AGENT; PLANT EXTRACT; POLYPHENOL DERIVATIVE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; NFE2L2 PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; APPLE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DPPH RADICAL SCAVENGING ASSAY; EXPERIMENTAL LIVER INJURY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; KUPFFER CELL; LIPID PEROXIDATION; LIVER; LIVER CELL; LIVER HOMOGENATE; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUNEL ASSAY; ANIMAL; CHEMICAL AND DRUG INDUCED LIVER INJURY; CHEMISTRY; DRUG EFFECTS; FRUIT; LIVER FUNCTION TEST; MALUS; METABOLISM; PATHOLOGY;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CARBON TETRACHLORIDE; CHEMICAL AND DRUG INDUCED LIVER INJURY; DOSE-RESPONSE RELATIONSHIP, DRUG; FRUIT; LIVER; LIVER FUNCTION TESTS; MALE; MALUS; MICE; NF-E2-RELATED FACTOR 2; PLANT EXTRACTS;

EID: 84994558646     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327115627689     Document Type: Article

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