Oxymatrine triggers apoptosis by regulating Bcl-2 family proteins and activating caspase-3/caspase-9 pathway in human leukemia HL-60 cells

Tumor Biology

Volumn 35, Issue 6, 2014, Pages 5409-5415

  Liu, Jun ^a   Yao, Yazhou ^b   Ding, Huifang ^c   Chen, Renan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b Baoji Center Hospital of Shanxi Province   (China)

^c Department of Otolaryngology   (China)

Author keywords

Apoptosis; Bax Bcl 2; Caspase; HL 60; Oxymatrine

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OXYMATRINE; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DOSE TIME EFFECT RELATION; DOWN REGULATION; ENZYME ACTIVATION; G2 PHASE CELL CYCLE CHECKPOINT; HL 60 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; S PHASE CELL CYCLE CHECKPOINT; UPREGULATION; WESTERN BLOTTING;

ALKALOIDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CELL CYCLE CHECKPOINTS; HL-60 CELLS; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; QUINOLIZINES; SIGNAL TRANSDUCTION;

EID: 84904765047     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1705-7     Document Type: Article

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